- Must visit
Smithsonian National Museum of Natural History
One of the world’s most visited natural history museums, known for dinosaur fossils, the Hope Diamond, and broad family-friendly exhibits.
Cheapest price
$306
Average price
$343
Fastest journey
2 d 19 h 5 m
Average duration
2 d 19 h 5 m
Buses per day
2
Distance
3922 km
The best way to find a cheap bus ticket from South San Francisco, CA to Washington, DC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from South San Francisco, CA to Washington, DC will cost around $343 if you buy it on the day, but the cheapest tickets can be found for only $306.
Of the 2 buses that leave South San Francisco, CA for Washington, DC on Thu, Jul 09, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jul 09 the direct buses cover the 3922 km distance in an average of 2 d 19 h 5 m but if you time it right, some buses will get you there in just 2 d 19 h 5 m .
On Thu, Jul 09 the slowest buses will take 2 d 19 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from South San Francisco, CA to Washington, DC among Omio's users. If you are prioritising price take the flight with prices starting from $159. For those with little time consider booking a flight which can get you there in 5h 15m. The ticket price range depends on the travel mode: a flight costs an average of $159, and a train costs an average of $252.
Distance: 2437 miles (3922 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$323 Average price | $828 Average price | $259 Average price Cheapest | $662 Average price (fuel + tolls) |
72h 12m Average total duration 71h 42m Onboard + 30m Additional time* | 70h 19m Average total duration 69h 49m Onboard + 30m Additional time* | 8h 15m Average total duration Fastest 5h 15m Onboard + 3h 0m Additional time* | 41h 22m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from South San Francisco, CA to Washington, DC:
A flight is $64 (€53) less than a bus for this route with tickets for a bus from South San Francisco, CA to Washington, DC costing on average $323 (€266).
A flight is $569 (€468) less than a train for this route with tickets for a train from South San Francisco, CA to Washington, DC costing on average $828 (€681).
Other travel options to Washington, DC take longer:
Train takes on average 69h 49m.
Bus takes on average 71h 42m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 05:40AM | Arrival Time 04:20PM | Duration 82h40 | Departure days Mon, Wed, Thu | Cheapest price $166 |
Operator Greyhound | Departure Time 06:25AM | Arrival Time 04:20PM | Duration 81h55 | Departure days Thu | Cheapest price $409 |
Operator Greyhound | Departure Time 06:40AM | Arrival Time 05:20PM | Duration 82h40 | Departure days Tue, Wed, Thu | Cheapest price $326 |
Operator Greyhound | Departure Time 02:30PM | Arrival Time 03:20PM | Duration 72h50 | Departure days Mon, Sun | Cheapest price $236 |
Operator Greyhound | Departure Time 08:30PM | Arrival Time 03:30PM | Duration 67h00 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $160 |
Operator Greyhound | Departure Time 09:30PM | Arrival Time 03:35PM | Duration 66h05 | Departure days Thu, Fri, Sat, Sun | Cheapest price $272 |
The table below shows live departures for South San Francisco, CA to Washington, DC buses for today, Wednesday, July 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:40 AM South San Francisco, CA | 76h05 | 9:45 AM Washington, DC | 0 transfersDirect | |
![]() | 6:25 AM South San Francisco, CA | 81h55 | 4:20 PM Washington, DC | 0 transfersDirect | |
![]() | 6:40 AM South San Francisco, CA | 75h55 | 10:35 AM Washington, DC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from South San Francisco, CA to Washington, DC run on average 15 times per day, taking around 71h 42m. Cheap bus tickets for this journey start at $121 (€100) if you book in advance.
The earliest bus runs at 00:40, the last at 23:55. The fastest bus covers the 2437 miles (3922 km) distance in 66h 5m.
Distance 2437 miles (3922 km) |
Average bus duration 71h 42m |
Cheapest ticket price $121 (€100) |
Buses per day 15 |
Fastest bus 66h 5m |
First bus 12:40 AM |
Last bus 11:55 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Discover the best of Washington — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Washington trip today.
One of the world’s most visited natural history museums, known for dinosaur fossils, the Hope Diamond, and broad family-friendly exhibits.
Flagship Smithsonian museum covering aviation and spaceflight, with iconic aircraft, spacecraft, and major interactive exhibits.
Premier art museum with strong collections from the Middle Ages to modern art, plus sculpture garden and rotating exhibitions.
The city’s grand ceremonial park lined with Smithsonian museums, memorials, and iconic government buildings.
Historic neighborhood of cobblestone streets, waterfront walks, rowhouses, and some of Washington’s most photogenic corners.
Scenic waterside loop famous for cherry blossoms and views of major memorials, especially popular for sunrise and spring visits.
Washington’s signature sausage, usually smoky and spicy, served on a bun with chili, mustard, and onions. It is one of the city’s most iconic street foods.
A sweet-tangy sauce closely associated with Washington carryout culture, often paired with fried chicken wings and fries. It is a local comfort-food staple.
Steamed or picked blue crab from the nearby Chesapeake region is deeply tied to local food traditions. It is especially popular in warmer months.
Celebrated upscale restaurant with creative small plates and a warm, energetic atmosphere. It is one of Washington’s best-known modern dining destinations.
A classic, long-running Washington institution known for oysters, crab cakes, and traditional American fare in an elegant historic atmosphere.
Bustling brasserie known for polished French classics, strong brunch, and a stylish dining room that is popular with both locals and visitors.
Prices are high for hotels and dining, especially downtown. Free museums help balance daily costs.
Tip 18-20% at restaurants. USD 1-2 per drink at bars, round up taxis, and tip hotel staff USD 2-5.
Official public transport app
L'Enfant Plaza, Washington, DC -> Metro Center, Washington, DC
Find answers to the most common questions about traveling from South San Francisco, CA to Washington, DC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Washington, DC, this guide helps you travel smarter and with confidence.

Most South San Francisco, CA to Washington, DC buses use the San Francisco, Transit Center Bay 29 to Washington, Columbus Circle, Union Station station pair, with some services arriving at Washington, DuPont Circle (Connecticut Ave. NW / 20th St. NW). Use this guide to compare South San Francisco, CA and Washington, DC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Washington, Columbus Circle, Union Station is 2 km from Washington city centre. Public transport options include:
Washington, Columbus Circle, Union Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: McDonald's (in the station), Shake Shack (in the station)
Free Wi-Fi. ATMs are located near the main entrance and food court.
Ticket office support is available at Washington, Columbus Circle, Union Station.
Available at Washington, Columbus Circle, Union Station: Parking, Taxis, WC.
Accessibility facilities are available at Washington, Columbus Circle, Union Station: Elevators, ramps.
Here are some other resources that might have the information you need