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The cheapest and fastest buses from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
Showing times and prices for Dec 22
Cheapest price
$33
Average price
$34
Fastest journey
2 h 55 m
Average duration
3 h 47 m
Buses per day
3
Distance
179 km
Cheap tickets
The best way to find a cheap bus ticket from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA will cost around $34 if you buy it on the day, but the cheapest tickets can be found for only $33.
Fast buses
Of the 3 buses that leave Union Station, Los Angeles, CA for Santa Fe Depot, San Diego, CA on Mon, Dec 22, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Dec 22 the direct buses cover the 179 km distance in an average of 3 h 47 m but if you time it right, some buses will get you there in just 2 h 55 m .
On Mon, Dec 22 the slowest buses will take 4 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:50PM2h55
Union Station, Los Angeles, CA03:45PMSanta Fe Depot, San Diego, CA
$331One-way
0 transfers
11:30PM3h45
Union Station, Los Angeles, CA03:15AMSanta Fe Depot, San Diego, CA
$331One-way
0 transfers
09:15PM4h40
Union Station, Los Angeles, CA01:55AMSanta Fe Depot, San Diego, CA
$341One-way
0 transfers
12:50PM2h55
Union Station, Los Angeles, CA03:45PMSanta Fe Depot, San Diego, CA
$331One-way
0 transfers
11:30PM3h45
Union Station, Los Angeles, CA03:15AMSanta Fe Depot, San Diego, CA
$331One-way
0 transfers
09:15PM4h40
Union Station, Los Angeles, CA01:55AMSanta Fe Depot, San Diego, CA
$341One-way
0 transfers
Union Station, Los Angeles, CA - Santa Fe Depot, San Diego, CACompare FlixBus, Greyhound, Infobus
$28
2h 55m
29 a day
Power plugs
Wifi
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Seat reservation
$32
3h 20m
3 a day
Power plugs
Wifi
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Seat reservation
$43
7h 45m
28 a day
Power plugs
Wifi
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Seat reservation
Travel Information
Compare bus, train, and flight for Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
Omio recommends booking the train as it is the most popular option from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €21. For those with little time consider booking a flight which can get you there in 2h 27m. The ticket price range depends on the travel mode: a bus costs an average of €21, and a flight costs an average of €94.
Distance: 111 miles (179 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€27 Average price Cheapest | €33 Average price | €179 Average price |
3h 28m Average total duration 2h 58m Onboard + 30m Additional time* | 3h 25m Average total duration 2h 55m Onboard + 30m Additional time* | 5h 27m Average total duration Fastest 2h 27m Onboard + 3h 0m Additional time* |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 06:20AM | Arrival Time 10:05AM | Duration 3h45 | Departure days Fri, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 06:55AM | Arrival Time 09:40AM | Duration 2h45 | Departure days Fri, Sun | Cheapest price $42 |
Operator Greyhound | Departure Time 08:20AM | Arrival Time 11:45AM | Duration 3h25 | Departure days Fri, Sun | Cheapest price $48 |
Operator FlixBus | Departure Time 10:25AM | Arrival Time 02:10PM | Duration 3h45 | Departure days Fri, Sun | Cheapest price $37 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 01:40PM | Duration 2h45 | Departure days Fri, Sun | Cheapest price $37 |
Operator FlixBus | Departure Time 12:25PM | Arrival Time 04:25PM | Duration 4h00 | Departure days Fri, Sun | Cheapest price $40 |
Operator FlixBus | Departure Time 01:30PM | Arrival Time 05:35PM | Duration 4h05 | Departure days Fri, Sun | Cheapest price $48 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 04:55PM | Duration 2h35 | Departure days Fri, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 05:20PM | Duration 2h35 | Departure days Fri, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 10:15PM | Duration 3h45 | Departure days Fri, Sun | Cheapest price $37 |
Operator Greyhound | Departure Time 08:20PM | Arrival Time 11:50PM | Duration 3h30 | Departure days Fri, Sun | Cheapest price $48 |
Live departures
Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus times
The table below shows live departures for Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA buses for today, Sunday, December 21. You can also manually refresh the results below to see updated bus journeys.
Last updated at 5:43 AM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus | 2:20 PM Los Angeles, Gayley / Strathmore, CA | 3h45 | 6:05 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 0 transfersDirect | |
| FlixBus | 2:20 PM Los Angeles, Gayley / Strathmore, CA | 3h20 | 5:40 PM La Jolla, UCSD Health La Jolla Station, CA | 0 transfersDirect | |
| FlixBus | 2:55 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 2h45 | 5:40 PM La Jolla, UCSD Health La Jolla Station, CA | 0 transfersDirect | |
| FlixBus | 2:55 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 3h10 | 6:05 PM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 0 transfersDirect | |
 | 4:20 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 3h25 | 7:45 PM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
| FlixBus | 6:25 PM Los Angles, S Hope St. USC Parking, CA | 3h45 | 10:10 PM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
| FlixBus | 6:25 PM Los Angles, S Hope St. USC Parking, CA | 3h15 | 9:40 PM La Jolla, UCSD Health La Jolla Station, CA | 0 transfersDirect | |
| FlixBus | 6:55 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 2h45 | 9:40 PM La Jolla, UCSD Health La Jolla Station, CA | 0 transfersDirect | |
| FlixBus | 6:55 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 3h15 | 10:10 PM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
| FlixBus | 8:25 PM Los Angeles, Cesar E Chavez / Vignes, CA | 4h00 | 12:25 AM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
| FlixBus | 8:25 PM Los Angeles, Cesar E Chavez / Vignes, CA | 3h30 | 11:55 PM La Jolla, UCSD Health La Jolla Station, CA | 0 transfersDirect | |
| FlixBus | 9:30 PM Los Angeles, Cesar E Chavez / Vignes, CA | 4h05 | 1:35 AM La Jolla, UCSD Health La Jolla Station, CA | 0 transfersDirect | |
| FlixBus | 9:30 PM Los Angeles, Cesar E Chavez / Vignes, CA | 4h40 | 2:10 AM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
| FlixBus | 10:20 PM Los Angeles, Cesar E Chavez / Vignes, CA | 2h35 | 12:55 AM La Jolla, UCSD Health La Jolla Station, CA | 0 transfersDirect | |
| FlixBus | 10:20 PM Los Angeles, Cesar E Chavez / Vignes, CA | 3h00 | 1:20 AM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
| FlixBus | 10:45 PM Downey, Stonewood Center (251 Stonewood St), CA | 2h35 | 1:20 AM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
| FlixBus | 10:45 PM Downey, Stonewood Center (251 Stonewood St), CA | 2h10 | 12:55 AM La Jolla, UCSD Health La Jolla Station, CA | 0 transfersDirect | |
| Monday, December 22 | |||||
| FlixBus | 2:30 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 3h45 | 6:15 AM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA | 0 transfersDirect | |
| FlixBus | 2:30 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 3h15 | 5:45 AM La Jolla, UCSD Health La Jolla Station, CA | 0 transfersDirect | |
| 4:20 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA | 3h30 | 7:50 AM San Diego, Congress Street (Old Town Park), CA | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mon
Dec 22
Dec 22
Tue
Dec 23
Dec 23
Wed
Dec 24
Dec 24
Thu
Dec 25
Dec 25
Fri
Dec 26
Dec 26
Sat
Dec 27
Dec 27
Sun
Dec 28
Dec 28
Journey information
Overview: Bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
USAUSA
Buses from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA run on average 30 times per day, taking around 2h 58m. Cheap bus tickets for this journey start at $27 (€21) if you book in advance.
There are 29 buses per day. The earliest bus runs at 12:50, the last at 23:30. The fastest bus covers the 111 miles (179 km) distance in 2h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 111 miles (179 km) |
Average bus duration 2h 58m |
Cheapest ticket price $27 (€21) |
Buses per day 30 |
Direct buses 29 |
Fastest bus 2h 35m |
First bus 12:50 |
Last bus 23:30 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, Greyhound, Infobus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CAYou can travel by bus between Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with FlixBus, Greyhound, Infobus for as low as $27 (€21). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
2h 55m
Cheapest Price
$28 (€23)
FlixBus frequency
29 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Infobus
About
Infobus is an international IT company that operates as an online service for finding and purchasing bus, train, and plane tickets, rather than being a bus company itself. Established in 2002, Infobus acts as an intermediary between passengers and various transport carriers, particularly helping smaller bus companies offer online booking services. They utilize their own "BusSystem" to manage routes and ticket sales globally. Infobus covers over 30 countries and 300 cities, offering a wide range of routes and daily departures. While amenities can vary by carrier, Infobus aims to provide affordable and convenient travel with features like online booking, 24/7 support, and prompt notifications.
Luggage & cancellation policy
Average Duration
7h 45m
Cheapest Price
$43 (€35)
Infobus frequency
28 a day
Luggage included
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Transport for wheelchairs and mobility aids.
Bikes
Bikes are allowed; may require prior reservation and an additional fee.
Pets
Small pets allowed in carriers; larger pets may require a separate ticket.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
3h 20m
Cheapest Price
$32 (€26)
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
FAQs: Bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
Find answers to the most common questions about traveling from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA can start from as little as $31 (€24) when you book in advance. The average bus ticket price for Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is $36 (€29); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time between Union Station, Los Angeles, CA and Santa Fe Depot, San Diego, CA is on average 2 h 40 min for the 110 mile (178 km) long journey, but the time it takes to go to Santa Fe Depot, San Diego, CA from Union Station, Los Angeles, CA by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA leaves at 1: 00PM. Plan your trip with the Journey Planner from Omio.
The last bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA leaves at 9: 55PM.
Yes, there are 17 direct buses a day from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
Take the Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus with FlixBus, Greyhound or Infobus. However, it's always good to check out all possible bus companies for the journey to Santa Fe Depot, San Diego, CA from Union Station, Los Angeles, CA as there might be differences in the amenities they offer.
A trip to Santa Fe Depot, San Diego, CA from Union Station, Los Angeles, CA is worth doing but not as a day trip with a journey time of 2 h 40 min each way. Check with Omio app the best way to travel.
The cheapest month to travel from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by bus is September.
You have options as you can travel to Santa Fe Depot, San Diego, CA from Union Station, Los Angeles, CA 3 different ways: bus, train or flight.
Yes, the following accessibility options are available when taking the bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
Yes, there are bathrooms on board the bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA for bus providers FlixBus, Greyhound and Infobus.
Yes, bikes are allowed on board the bus with bus companies FlixBus, Greyhound and Infobus.
Whether you can cancel your bus ticket from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA depends on the bus providers:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
To find the cheapest bus tickets for your trip from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
Yes, the following luggage options are included when booking a bus ticket from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Yes, the following additional luggage options are available when booking a bus ticket from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
- FlixBus
- Additional luggage can be purchased for a fee.
- Greyhound
- $15 per additional bag.
- Infobus
- 10€ per additional bag.
Yes, you can bring your pet on the bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
- Infobus
- Small pets allowed in carriers
- Larger pets may require a separate ticket.
You can reserve your seat on the bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus providers: FlixBus, Greyhound and Infobus
Yes, there are USB plugs on board the bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus providers: FlixBus, Greyhound and Infobus.
Yes, there is Wifi on board the bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus companies: FlixBus, Greyhound and Infobus.
Most popular bus connections from Union Station, Los Angeles, CA
More options for your journey from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
Here are some other resources that might have the information you need
Most popular buses to and from Santa Fe Depot, San Diego, CA and Union Station, Los Angeles, CA
Most popular bus connections to Santa Fe Depot, San Diego, CA
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