The cheapest and fastest buses from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
Cheapest price
$33
Average price
$34
Fastest journey
2 h 55 m
Average duration
3 h 47 m
Buses per day
3
Distance
179 km
The best way to find a cheap bus ticket from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA will cost around $34 if you buy it on the day, but the cheapest tickets can be found for only $33.
Of the 3 buses that leave Union Station, Los Angeles, CA for Santa Fe Depot, San Diego, CA on Fri, Nov 07, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct buses cover the 179 km distance in an average of 3 h 47 m but if you time it right, some buses will get you there in just 2 h 55 m .
On Fri, Nov 07 the slowest buses will take 4 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare bus, train, and flight for Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
Omio recommends booking the train as it is the most popular option from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €21. For those with little time consider booking a flight which can get you there in 2h 27m. The ticket price range depends on the travel mode: a bus costs an average of €21, and a flight costs an average of €94.
Distance: 111 miles (179 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€27 Average price Cheapest | €33 Average price | €179 Average price |
3h 28m Average total duration 2h 58m Onboard + 30m Additional time* | 3h 25m Average total duration 2h 55m Onboard + 30m Additional time* | 5h 27m Average total duration Fastest 2h 27m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Infobus | Departure Time 12:05AM | Arrival Time 03:00AM | Duration 2h55 | Departure days Wed | Cheapest price $60 |
Operator Infobus | Departure Time 01:00AM | Arrival Time 04:15AM | Duration 3h15 | Departure days Wed | Cheapest price $57 |
Operator Infobus | Departure Time 02:00AM | Arrival Time 05:30AM | Duration 3h30 | Departure days Wed | Cheapest price $57 |
Operator Infobus | Departure Time 04:00AM | Arrival Time 06:45AM | Duration 2h45 | Departure days Wed | Cheapest price $65 |
Operator Infobus | Departure Time 05:00AM | Arrival Time 09:00AM | Duration 4h00 | Departure days Wed | Cheapest price $57 |
Operator Infobus | Departure Time 05:15AM | Arrival Time 08:34AM | Duration 3h19 | Departure days Wed | Cheapest price $88 |
Operator FlixBus | Departure Time 06:20AM | Arrival Time 10:05AM | Duration 3h45 | Departure days Mon | Cheapest price $36 |
Operator FlixBus | Departure Time 06:55AM | Arrival Time 09:40AM | Duration 2h45 | Departure days Mon | Cheapest price $36 |
Operator Infobus | Departure Time 07:30AM | Arrival Time 09:49AM | Duration 2h19 | Departure days Wed | Cheapest price $55 |
Operator Infobus | Departure Time 08:00AM | Arrival Time 12:15PM | Duration 4h15 | Departure days Wed | Cheapest price $57 |
Operator Greyhound | Departure Time 08:20AM | Arrival Time 11:45AM | Duration 3h25 | Departure days Mon, Wed | Cheapest price $34 |
Operator Infobus | Departure Time 09:30AM | Arrival Time 12:49PM | Duration 3h19 | Departure days Wed | Cheapest price $88 |
Operator FlixBus | Departure Time 10:25AM | Arrival Time 02:10PM | Duration 3h45 | Departure days Mon | Cheapest price $36 |
Operator FlixBus | Departure Time 10:55AM | Arrival Time 01:40PM | Duration 2h45 | Departure days Mon | Cheapest price $36 |
Operator Infobus | Departure Time 11:30AM | Arrival Time 02:19PM | Duration 2h49 | Departure days Wed | Cheapest price $55 |
Operator FlixBus | Departure Time 12:25PM | Arrival Time 03:55PM | Duration 3h30 | Departure days Mon, Wed | Cheapest price $32 |
Operator FlixBus | Departure Time 01:30PM | Arrival Time 05:35PM | Duration 4h05 | Departure days Mon, Wed | Cheapest price $39 |
Operator Infobus | Departure Time 01:30PM | Arrival Time 05:45PM | Duration 4h15 | Departure days Wed | Cheapest price $60 |
Operator Infobus | Departure Time 02:00PM | Arrival Time 06:30PM | Duration 4h30 | Departure days Wed | Cheapest price $72 |
Operator Infobus | Departure Time 02:15PM | Arrival Time 05:00PM | Duration 2h45 | Departure days Wed | Cheapest price $65 |
Operator Infobus | Departure Time 02:45PM | Arrival Time 07:10PM | Duration 4h25 | Departure days Wed | Cheapest price $57 |
Operator Infobus | Departure Time 03:30PM | Arrival Time 07:30PM | Duration 4h00 | Departure days Wed | Cheapest price $60 |
Operator Infobus | Departure Time 04:00PM | Arrival Time 06:49PM | Duration 2h49 | Departure days Wed | Cheapest price $55 |
Operator Infobus | Departure Time 06:00PM | Arrival Time 09:19PM | Duration 3h19 | Departure days Wed | Cheapest price $88 |
Operator FlixBus | Departure Time 06:30PM | Arrival Time 10:15PM | Duration 3h45 | Departure days Mon, Wed | Cheapest price $32 |
Operator Infobus | Departure Time 08:00PM | Arrival Time 10:49PM | Duration 2h49 | Departure days Wed | Cheapest price $55 |
Operator Greyhound | Departure Time 08:20PM | Arrival Time 11:50PM | Duration 3h30 | Departure days Mon, Wed | Cheapest price $36 |
Live departures
Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus times
The table below shows live departures for Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA buses for today, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:50 PM Union Station, Los Angeles, CA | 2h55 | 3:45 PM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
![]() | 10:35 PM Union Station, Los Angeles, CA | 3h50 | 2:25 AM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Journey information
Overview: Bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
Distance 111 miles (179 km) |
Average bus duration 2h 58m |
Cheapest ticket price $26 (€21) |
Buses per day 30 |
Direct buses 29 |
Fastest bus 2h 35m |
First bus 12:50 |
Last bus 23:30 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA start from as low as $26 (€21) if booked well in advance.
- Standard Fares: Typically, trains cost $33 (€27) depending on the train type and class.
Bus providers: FlixBus, Greyhound, Infobus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CAYou can travel by bus between Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with FlixBus, Greyhound, Infobus for as low as $26 (€21). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
Greyhound
FAQs: Bus from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
Find answers to the most common questions about traveling from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
To find the cheapest bus tickets for your trip from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- Additional luggage can be purchased for a fee.
- Greyhound
- $15 per additional bag.
- Infobus
- 10€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
- Infobus
- Small pets allowed in carriers
- Larger pets may require a separate ticket.
Most popular bus connections from Union Station, Los Angeles, CA
More options for your journey from Union Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
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