The cheapest and fastest buses from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA
- Cheapest price on Nov 03
- $27
- Average ticket price on Nov 03
- $31
- Fastest journey on Nov 03
- 2 h 45 m
- Average journey duration on Nov 03
- 3 h 25 m
- Buses on Nov 03
- 4
- Distance
- 179 km
The best way to find a cheap bus ticket from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA will cost around $31 if you buy it on the day, but the cheapest tickets can be found for only $27.
On Tue, Nov 03, we found 4 buses from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA, including 4 direct services.
On Tue, Nov 03 the direct buses cover the 179 km distance in an average of 3 h 25 m but if you time it right, some buses will get you there in just 2 h 45 m .
On Tue, Nov 03 the slowest buses will take 4 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

7:40 PM 4h15 Santa Fe Depot, San Diego, CA 11:55 PM Union Station, Los Angeles, CA $27 1 One-way 0 transfers
9:35 PM 3h20 Santa Fe Depot, San Diego, CA 12:55 AM Union Station, Los Angeles, CA $28 1 One-way 0 transfers
8:35 PM 3h20 Santa Fe Depot, San Diego, CA 11:55 PM Union Station, Los Angeles, CA $33 1 One-way 0 transfers
3:35 AM 2h45 Santa Fe Depot, San Diego, CA 6:20 AM Union Station, Los Angeles, CA $34 1 One-way 0 transfers

3:35 AM 2h45 Santa Fe Depot, San Diego, CA 6:20 AM Union Station, Los Angeles, CA $34 1 One-way 0 transfers
9:35 PM 3h20 Santa Fe Depot, San Diego, CA 12:55 AM Union Station, Los Angeles, CA $28 1 One-way 0 transfers
8:35 PM 3h20 Santa Fe Depot, San Diego, CA 11:55 PM Union Station, Los Angeles, CA $33 1 One-way 0 transfers
7:40 PM 4h15 Santa Fe Depot, San Diego, CA 11:55 PM Union Station, Los Angeles, CA $27 1 One-way 0 transfers
Journey information
Overview: Bus from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA
Buses from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA run on average 22 times per day, taking around 3h 21m. Cheap bus tickets for this journey start at $21 (€18) if you book in advance.
There are 22 buses per day. The earliest bus runs at 00:20, the last at 20:35. The fastest bus covers the 111 miles (179 km) distance in 1h 55m.
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Journey facts
- Distance111 miles (179 km)
- Average bus duration3h 21m
- Cheapest ticket price$21 (€18)
- Buses per day22
- Direct buses22
- Fastest bus1h 55m
- First bus12:20 AM
- Last bus8:35 PM
- Cheapest MonthAug
- Cheapest DayTue
- High SeasonJan - Mar
- Low SeasonJul - Sep
- Busiest DaySun
- Least Busy DayFri
- Best time to book14 days
Understand & plan this route
Explore this journey
Book with confidence
Frequently asked questions about your Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA.
Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 03:35AM | Arrival Time 06:20AM | Duration 2h45 | Departure days Wed | Cheapest price $34 |
Operator Greyhound | Departure Time 04:55AM | Arrival Time 09:15AM | Duration 4h20 | Departure days Thu | Cheapest price $31 |
Operator Tufesa Internacional | Departure Time 06:30AM | Arrival Time 09:45AM | Duration 3h15 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $50 |
Operator Futura Net | Departure Time 07:51AM | Arrival Time 10:36AM | Duration 2h45 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $77 |
Operator Futura Net | Departure Time 09:51AM | Arrival Time 12:36PM | Duration 2h45 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $77 |
Operator Tufesa Internacional | Departure Time 10:45AM | Arrival Time 02:35PM | Duration 3h50 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $76 |
Operator Tufesa Internacional | Departure Time 11:30AM | Arrival Time 02:30PM | Duration 3h00 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $50 |
Operator Futura Net | Departure Time 11:51AM | Arrival Time 02:56PM | Duration 3h05 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $77 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 04:55PM | Duration 4h15 | Departure days Thu | Cheapest price $28 |
Operator FlixBus | Departure Time 01:10PM | Arrival Time 04:55PM | Duration 3h45 | Departure days Thu | Cheapest price $27 |
Operator Futura Net | Departure Time 01:51PM | Arrival Time 04:56PM | Duration 3h05 | Departure days Wed, Fri, Sat, Sun | Cheapest price $77 |
Operator Futura Net | Departure Time 03:51PM | Arrival Time 06:56PM | Duration 3h05 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $77 |
Operator Futura Net | Departure Time 05:51PM | Arrival Time 08:56PM | Duration 3h05 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $77 |
Operator Greyhound | Departure Time 07:10PM | Arrival Time 10:20PM | Duration 3h10 | Departure days Thu | Cheapest price $28 |
Operator FlixBus | Departure Time 07:40PM | Arrival Time 11:55PM | Duration 4h15 | Departure days Tue | Cheapest price $27 |
Operator Futura Net | Departure Time 07:51PM | Arrival Time 10:56PM | Duration 3h05 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $77 |
Operator Tufesa Internacional | Departure Time 08:20PM | Arrival Time 12:20AM | Duration 4h00 | Departure days Mon, Wed, Fri, Sat, Sun | Cheapest price $50 |
Operator FlixBus | Departure Time 08:35PM | Arrival Time 11:55PM | Duration 3h20 | Departure days Tue | Cheapest price $33 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 12:55AM | Duration 3h20 | Departure days Tue | Cheapest price $28 |
Live departures
Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA bus times
The table below shows live departures for Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
0 | 10:45 AM Santa Fe Depot, San Diego, CA | 3h50 | 2:35 PM Union Station, Los Angeles, CA | 0 transfersDirect | |
0 | 11:30 AM Santa Fe Depot, San Diego, CA | 3h00 | 2:30 PM Union Station, Los Angeles, CA | 0 transfersDirect | |
0 | 11:51 AM Santa Fe Depot, San Diego, CA | 3h05 | 2:56 PM Union Station, Los Angeles, CA | 0 transfersDirect | |
0 | 3:51 PM Santa Fe Depot, San Diego, CA | 3h05 | 6:56 PM Union Station, Los Angeles, CA | 0 transfersDirect | |
0 | 5:51 PM Santa Fe Depot, San Diego, CA | 3h05 | 8:56 PM Union Station, Los Angeles, CA | 0 transfersDirect | |
0 | 7:51 PM Santa Fe Depot, San Diego, CA | 3h05 | 10:56 PM Union Station, Los Angeles, CA | 0 transfersDirect | |
0 | 8:20 PM Santa Fe Depot, San Diego, CA | 4h00 | 12:20 AM Union Station, Los Angeles, CA | 0 transfersDirect | |
| Tuesday, November 3 | |||||
![]() | 3:35 AM Santa Fe Depot, San Diego, CA | 2h45 | 6:20 AM Union Station, Los Angeles, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound, Futura Net, Infobus or Tufesa Internacional to find the best option for your trip from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA.
Why book with Omio over Wanderu, Trainline or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound, Futura Net, Infobus or Tufesa Internacional to find the best option for your trip from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA.
Bus companies
Bus companies from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA
Buses from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA with FlixBus, Infobus, and Futura Net. Overnight buses available on this route with FlixBus and Greyhound. Use the details below to compare onboard facilities.
FlixBus
Infobus
Greyhound
Futura Net
Tufesa Internacional
Companies, tickets, and onboard amenities between Santa Fe Depot, San Diego, CA and Union Station, Los Angeles, CA
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
FAQs: Bus from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA
Find answers to the most common questions about traveling from Santa Fe Depot, San Diego, CA to Union Station, Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Union Station, Los Angeles, CA, this guide helps you travel smarter and with confidence.



