Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus with FlixBus

Fri, Nov 07
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The cheapest and fastest buses from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Showing times and prices for Nov 07

Cheapest price

$33

Average price

$33

Fastest journey

2 h 55 m

Average duration

2 h 55 m

Buses per day

1

Distance

204 km

Cheap tickets

The best way to find a cheap bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA will cost around $33 if you buy it on the day, but the cheapest tickets can be found for only $33.

Fast buses

Of the 1 buses that leave Van Nuys, Metrolink Station, Los Angeles, CA for Santa Fe Depot, San Diego, CA on Fri, Nov 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, Nov 07 the direct buses cover the 204 km distance in an average of 2 h 55 m but if you time it right, some buses will get you there in just 2 h 55 m .

On Fri, Nov 07 the slowest buses will take 2 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
12:50PM2h55
Van Nuys, Metrolink Station, Los Angeles, CA
03:45PMSanta Fe Depot, San Diego, CA
$331One-way
0 transfers

Travel Information

Compare train, bus, and flight for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Omio recommends booking the train as it is the most popular option from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €19. For those with little time consider booking a bus which can get you there in 3h 40m. The ticket price range depends on the travel mode: a bus costs an average of €19, and a flight costs an average of €46.

Distance: 126 miles (204 km)

Compare bus with

Bus
Most popular
Train
Flight

€25

Average price

Cheapest

€36

Average price

€121

Average price

4h 10m

Average total duration

Fastest

3h 40m

Onboard

+

30m

Additional time*

4h 28m

Average total duration

3h 58m

Onboard

+

30m

Additional time*

12h 53m

Average total duration

9h 53m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
06:40AM
Arrival Time
11:45AM
Duration
5h05
Departure days
Thu
Cheapest price
$48
Operator
FlixBus
Departure Time
06:40AM
Arrival Time
02:10PM
Duration
7h30
Departure days
Thu
Cheapest price
$48
Operator
Greyhound
Departure Time
08:20AM
Arrival Time
11:45AM
Duration
3h25
Departure days
Thu
Cheapest price
$35
Operator
FlixBus
Departure Time
10:25AM
Arrival Time
02:10PM
Duration
3h45
Departure days
Thu
Cheapest price
$35
Operator
FlixBus
Departure Time
10:55AM
Arrival Time
01:40PM
Duration
2h45
Departure days
Thu
Cheapest price
$35
Operator
FlixBus
Departure Time
11:15AM
Arrival Time
04:25PM
Duration
5h10
Departure days
Thu
Cheapest price
$34
Operator
FlixBus
Departure Time
12:25PM
Arrival Time
04:25PM
Duration
4h00
Departure days
Thu
Cheapest price
$35
Operator
FlixBus
Departure Time
01:30PM
Arrival Time
05:35PM
Duration
4h05
Departure days
Thu
Cheapest price
$41
Operator
FlixBus
Departure Time
02:40PM
Arrival Time
10:15PM
Duration
7h35
Departure days
Thu
Cheapest price
$44
Operator
FlixBus
Departure Time
06:30PM
Arrival Time
10:15PM
Duration
3h45
Departure days
Thu
Cheapest price
$35
Operator
Greyhound
Departure Time
08:20PM
Arrival Time
11:50PM
Duration
3h30
Departure days
Thu
Cheapest price
$36

Live departures

Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus times

The table below shows live departures for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA buses for today, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.

Last updated at 2:53 PM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound4:20 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA
3h25
7:45 PM San Diego, Congress Street (Old Town Park), CA0 transfersDirect
meinfernbus_flixbusFlixBus6:25 PM Los Angles, S Hope St. USC Parking, CA
3h45
10:10 PM San Diego, Congress Street (Old Town Park), CA0 transfersDirect
meinfernbus_flixbusFlixBus6:25 PM Los Angles, S Hope St. USC Parking, CA
3h15
9:40 PM La Jolla, UCSD Health La Jolla Station, CA0 transfersDirect
meinfernbus_flixbusFlixBus6:55 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA
2h45
9:40 PM La Jolla, UCSD Health La Jolla Station, CA0 transfersDirect
meinfernbus_flixbusFlixBus6:55 PM Los Angeles, Patsaouras Transit Plaza (Union Station), CA
3h15
10:10 PM San Diego, Congress Street (Old Town Park), CA0 transfersDirect
meinfernbus_flixbusFlixBus7:15 PM San Fernando, Rinaldi St / Rincon Ave (Greyhound Bus Stop)
5h10
12:25 AM San Diego, Congress Street (Old Town Park), CA0 transfersDirect
meinfernbus_flixbusFlixBus7:15 PM San Fernando, Rinaldi St / Rincon Ave (Greyhound Bus Stop)
4h40
11:55 PM La Jolla, UCSD Health La Jolla Station, CA0 transfersDirect
meinfernbus_flixbusFlixBus8:25 PM Los Angeles, Cesar E Chavez / Vignes, CA
4h00
12:25 AM San Diego, Congress Street (Old Town Park), CA0 transfersDirect
meinfernbus_flixbusFlixBus8:25 PM Los Angeles, Cesar E Chavez / Vignes, CA
3h30
11:55 PM La Jolla, UCSD Health La Jolla Station, CA0 transfersDirect
meinfernbus_flixbusFlixBus9:30 PM Los Angeles, Cesar E Chavez / Vignes, CA
4h05
1:35 AM La Jolla, UCSD Health La Jolla Station, CA0 transfersDirect
meinfernbus_flixbusFlixBus9:30 PM Los Angeles, Cesar E Chavez / Vignes, CA
4h40
2:10 AM San Diego, Congress Street (Old Town Park), CA0 transfersDirect
meinfernbus_flixbusFlixBus · FlixBus10:40 PM San Fernando, Rinaldi St / Rincon Ave (Greyhound Bus Stop)
7h35
6:15 AM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA1 transfer
meinfernbus_flixbusFlixBus · FlixBus10:40 PM San Fernando, Rinaldi St / Rincon Ave (Greyhound Bus Stop)
7h05
5:45 AM La Jolla, UCSD Health La Jolla Station, CA1 transfer
Friday, November 7
meinfernbus_flixbusFlixBus2:30 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA
3h45
6:15 AM San Diego, West Harbor Drive (The Headquarters at Seaport District), CA0 transfersDirect
meinfernbus_flixbusFlixBus2:30 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA
3h15
5:45 AM La Jolla, UCSD Health La Jolla Station, CA0 transfersDirect
greyhound4:20 AM Los Angeles, Patsaouras Transit Plaza (Union Station), CA
3h30
7:50 AM San Diego, Congress Street (Old Town Park), CA0 transfersDirect
meinfernbus_flixbus12:50 PM Van Nuys, Metrolink Station, Los Angeles, CA
2h55
3:45 PM Santa Fe Depot, San Diego, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by train, bus, or flight

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Journey information

Overview: Bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

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Buses from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA run on average 18 times per day, taking around 3h 40m. Cheap bus tickets for this journey start at $23 (€19) if you book in advance.

There are 14 buses per day. The earliest bus runs at 12:50, the last at 21:45. The fastest bus covers the 126 miles (204 km) distance in 2h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
126 miles (204 km)
Average bus duration
3h 40m
Cheapest ticket price
$23 (€19)
Buses per day
18
Direct buses
14
Fastest bus
2h 35m
First bus
12:50
Last bus
21:45
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CAYou can travel by bus between Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with FlixBus for as low as $23 (€19). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Learn more about FlixBus
Luggage & cancellation policy
Average Duration
2h 35m
Cheapest Price
$28 (€22)
FlixBus frequency
27 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

FAQs: Bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Find answers to the most common questions about traveling from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA can start from as little as $31 (€26) when you book in advance. The average bus ticket price for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is $31 (€26); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is 5 h 25 min   to travel the 126 mile (204 km) long trip, with around there are 9 buses per day. Journey times can vary on weekends and holidays.
The bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA leaves at 10: 40PM. Plan your trip with the Journey Planner   from Omio.
There are 9 buses a day from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA which require at least one change with FlixBus or Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA, you can count on FlixBus or Greyhound for the best way to get you to Santa Fe Depot, San Diego, CA. You can also check all possible bus companies who offer a service from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA and compare the amenities they offer before buying a bus ticket.
The cheapest month for a bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is October.
You have options as you can travel from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA 3 different ways: train, bus or flight.
Yes, the following accessibility options are available when taking the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA for bus companies FlixBus and Greyhound.
Yes, bikes are allowed on board the bus with bus companies FlixBus and Greyhound.
Whether you can cancel your bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA depends on the bus providers:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

To find the cheapest bus tickets for your trip from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
    Yes, the following luggage options are included when booking a bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    • Greyhound
      • $15 per additional bag.
    Yes, you can bring your pet on the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus providers: FlixBus and Greyhound
    Yes, there are USB plugs on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus providers: FlixBus and Greyhound.
    Yes, there is Wifi on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus providers: FlixBus and Greyhound.

    More options for your journey from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

    Here are some other resources that might have the information you need

    Return journeys for buses from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA

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