Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus with FlixBus

Fri, Feb 06
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The cheapest and fastest buses from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Showing times and prices for Feb 07

Cheapest price

$27

Average price

$28

Fastest journey

3 h 15 m

Average duration

4 h

Buses per day

2

Distance

204 km

Cheap tickets

The best way to find a cheap bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA will cost around $28 if you buy it on the day, but the cheapest tickets can be found for only $27.

Fast buses

Of the 2 buses that leave Van Nuys, Metrolink Station, Los Angeles, CA for Santa Fe Depot, San Diego, CA on Sat, Feb 07, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Sat, Feb 07 the direct buses cover the 204 km distance in an average of 4 h but if you time it right, some buses will get you there in just 3 h 15 m .

On Sat, Feb 07 the slowest buses will take 4 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
02:30AM3h15
Van Nuys, Metrolink Station, Los Angeles, CA
05:45AMSanta Fe Depot, San Diego, CA
$271One-way
0 transfers
FlixBus
08:25PM4h45
Van Nuys, Metrolink Station, Los Angeles, CA
01:10AMSanta Fe Depot, San Diego, CA
$291One-way
0 transfers

Travel Information

Compare train, bus, and flight for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Omio recommends booking the train as it is the most popular option from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €20. For those with little time consider booking a train which can get you there in 3h 58m. The ticket price range depends on the travel mode: a bus costs an average of €20, and a flight costs an average of €242.

Distance: 126 miles (204 km)

Compare bus with

Bus
Most popular
Train
Flight

€26

Average price

Cheapest

€36

Average price

€288

Average price

4h 30m

Average total duration

4h 0m

Onboard

+

30m

Additional time*

4h 28m

Average total duration

Fastest

3h 58m

Onboard

+

30m

Additional time*

10h 0m

Average total duration

7h 0m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
06:20AM
Arrival Time
10:05AM
Duration
3h45
Departure days
Sun
Cheapest price
$31
Operator
Greyhound
Departure Time
06:40AM
Arrival Time
11:45AM
Duration
5h05
Departure days
Sun
Cheapest price
$46
Operator
FlixBus
Departure Time
06:40AM
Arrival Time
01:40PM
Duration
7h00
Departure days
Sun
Cheapest price
$45
Operator
FlixBus
Departure Time
06:55AM
Arrival Time
09:40AM
Duration
2h45
Departure days
Sun
Cheapest price
$31
Operator
Greyhound
Departure Time
08:20AM
Arrival Time
11:45AM
Duration
3h25
Departure days
Sun
Cheapest price
$34
Operator
FlixBus
Departure Time
10:25AM
Arrival Time
02:10PM
Duration
3h45
Departure days
Sun
Cheapest price
$31
Operator
FlixBus
Departure Time
10:55AM
Arrival Time
01:40PM
Duration
2h45
Departure days
Sun
Cheapest price
$31
Operator
FlixBus
Departure Time
11:15AM
Arrival Time
03:55PM
Duration
4h40
Departure days
Sun
Cheapest price
$32
Operator
FlixBus
Departure Time
12:25PM
Arrival Time
03:55PM
Duration
3h30
Departure days
Sun
Cheapest price
$33
Operator
FlixBus
Departure Time
01:30PM
Arrival Time
05:35PM
Duration
4h05
Departure days
Sun
Cheapest price
$39
Operator
FlixBus
Departure Time
02:20PM
Arrival Time
04:55PM
Duration
2h35
Departure days
Sun
Cheapest price
$33
Operator
FlixBus
Departure Time
02:40PM
Arrival Time
09:45PM
Duration
7h05
Departure days
Sun
Cheapest price
$45
Operator
FlixBus
Departure Time
02:45PM
Arrival Time
05:20PM
Duration
2h35
Departure days
Sun
Cheapest price
$33
Operator
FlixBus
Departure Time
06:30PM
Arrival Time
10:15PM
Duration
3h45
Departure days
Sun
Cheapest price
$29
Operator
Greyhound
Departure Time
08:20PM
Arrival Time
11:50PM
Duration
3h30
Departure days
Sun
Cheapest price
$33

Live departures

Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus times

The table below shows live departures for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA buses for today, Thursday, February 5. You can also manually refresh the results below to see updated bus journeys.

Last updated at 1:11 PM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus7:15 PM Van Nuys, Metrolink Station, Los Angeles, CA
4h40
11:55 PM Santa Fe Depot, San Diego, CA0 transfersDirect
Friday, February 6
meinfernbus_flixbus2:30 AM Van Nuys, Metrolink Station, Los Angeles, CA
3h15
5:45 AM Santa Fe Depot, San Diego, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Fri
Feb 06
Sat
Feb 07
Sun
Feb 08
Mon
Feb 09
Tue
Feb 10
Wed
Feb 11
Thu
Feb 12

Why should you book Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA buses with Omio?

FlixBus operates all buses services from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
Omio is an official ticket reseller for all your travel options from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of to find the best option for your trip from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.

Why book with Omio over Wanderu?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.

Journey information

Overview: Bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

USAUSA
USAUSA
Icon of bus

Buses from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA run on average 19 times per day, taking around 4h 0m. Cheap bus tickets for this journey start at $25 (€20) if you book in advance.

There are 14 buses per day. The earliest bus runs at 02:30, the last at 22:45. The fastest bus covers the 126 miles (204 km) distance in 2h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
126 miles (204 km)
Average bus duration
4h 0m
Cheapest ticket price
$25 (€20)
Buses per day
19
Direct buses
14
Fastest bus
2h 10m
First bus
02:30
Last bus
22:45
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CAYou can travel by bus between Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with FlixBus for as low as $25 (€20). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
2h 10m
Cheapest Price
$25 (€20)
FlixBus frequency
24 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

FAQs: Bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Find answers to the most common questions about traveling from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA can start from as little as $25 (€20) when you book in advance. The average bus ticket price for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is $32 (€26) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is 2h 10m to travel the 126 miles (204 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA leaves at 2:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA leaves at 10:45 PM.
Yes, there are 14 direct buses a day from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA, you can count on FlixBus for the best way to get you to Santa Fe Depot, San Diego, CA. You can also check all possible bus companies who offer a service between Van Nuys, Metrolink Station, Los Angeles, CA and Santa Fe Depot, San Diego, CA and compare the amenities they offer before buying a bus ticket.
A trip to Santa Fe Depot, San Diego, CA from Van Nuys, Metrolink Station, Los Angeles, CA is worth doing but not as a day trip with a journey time of 2h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is April.
It's helpful to compare your options as there are 3 ways to travel between Van Nuys, Metrolink Station, Los Angeles, CA and Santa Fe Depot, San Diego, CA including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA for bus company FlixBus.
Yes, the following accessibility options are available when taking the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
Yes, the following luggage options are included when booking a bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus company: FlixBus.

More options for your journey from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Here are some other resources that might have the information you need

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