Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus with FlixBus

Thu, May 07
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The cheapest and fastest buses from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Showing times and prices for May 08

Cheapest price

$35

Average price

$35

Fastest journey

4 h 15 m

Average duration

4 h 15 m

Buses per day

1

Distance

204 km

Cheap tickets

The best way to find a cheap bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA will cost around $35 if you buy it on the day, but the cheapest tickets can be found for only $35.

Fast buses

Of the 1 buses that leave Van Nuys, Metrolink Station, Los Angeles, CA for Santa Fe Depot, San Diego, CA on Fri, May 08, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Fri, May 08 the direct buses cover the 204 km distance in an average of 4 h 15 m but if you time it right, some buses will get you there in just 4 h 15 m .

On Fri, May 08 the slowest buses will take 4 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBus
    2:30 AM4h15
    Van Nuys, Metrolink Station, Los Angeles, CA
    6:45 AMSanta Fe Depot, San Diego, CA
    $351One-way
    0 transfers

Travel Information

Compare train, bus, and flight for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Omio recommends booking the train as it is the most popular option from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a train which can get you there in 3h 58m. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $304.

Distance: 126 miles (204 km)

Compare bus with

Bus
Most popular
Train
Flight
Driving

$33

Average price

Cheapest

$44

Average price

$420

Average price

$37

Average price

(fuel + tolls)

4h 30m

Average total duration

4h 0m

Onboard

+

30m

Additional time*

4h 28m

Average total duration

Fastest

3h 58m

Onboard

+

30m

Additional time*

8h 45m

Average total duration

5h 45m

Onboard

+

3h 0m

Additional time*

2h 38m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is a bus with an average price of $33 (€26).

This is compared to other travel options from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:

A bus is $12 (€9) less than a train for this route with tickets for a train from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA costing on average $44 (€35).

A bus is $387 (€309) less than a flight for this route with tickets for a flight from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA costing on average $420 (€335).

The fastest way to travel from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is by train with an average journey time of 3h 58m.

Other travel options to Santa Fe Depot, San Diego, CA take longer:

Bus takes on average 4h 0m.

Flight takes on average 5h 45m.

It's helpful to compare your options as there are 3 ways to travel between Van Nuys, Metrolink Station, Los Angeles, CA and Santa Fe Depot, San Diego, CA including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Live departures

Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus times

The table below shows live departures for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA buses for today, Wednesday, May 6. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus8:25 PM Van Nuys, Metrolink Station, Los Angeles, CA
3h30
11:55 PM Santa Fe Depot, San Diego, CA0 transfersDirect
Thursday, May 7
meinfernbus_flixbus2:30 AM Van Nuys, Metrolink Station, Los Angeles, CA
4h15
6:45 AM Santa Fe Depot, San Diego, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
May 07
Fri
May 08
Sat
May 09
Sun
May 10
Mon
May 11
Tue
May 12
Wed
May 13

Why should you book Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA buses with Omio?

FlixBus operates all buses services from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
Omio is an official ticket reseller for all your travel options from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.

Journey information

Overview: Bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

USAUSA
USAUSA
Icon of bus

Buses from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA run on average 19 times per day, taking around 4h 0m. Cheap bus tickets for this journey start at $24 (€19) if you book in advance.

There are 14 buses per day. The earliest bus runs at 02:30, the last at 22:45. The fastest bus covers the 126 miles (204 km) distance in 2h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
126 miles (204 km)
Average bus duration
4h 0m
Cheapest ticket price
$24 (€19)
Buses per day
19
Direct buses
14
Fastest bus
2h 10m
First bus
2:30 AM
Last bus
10:45 PM
Cheapest Month
Apr
Cheapest Day
Wed
High Season
Jan - Mar
Low Season
Apr - Jun
Busiest Day
Tue
Least Busy Day
Tue
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CAYou can travel by bus between Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with FlixBus for as low as $24 (€19). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
2h 10m
Cheapest Price
$24 (€19)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

FAQs: Bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Find answers to the most common questions about traveling from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA can start from as little as $24 (€19) when you book in advance. The average bus ticket price for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is $33 (€26) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is 2h 10m to travel the 126 miles (204 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA leaves at 2:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA leaves at 10:45 PM.
Yes, there are 14 direct buses a day from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with . Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA, you can count on FlixBus for the best way to get you to Santa Fe Depot, San Diego, CA. You can also check all possible bus companies who offer a service between Van Nuys, Metrolink Station, Los Angeles, CA and Santa Fe Depot, San Diego, CA and compare the amenities they offer before buying a bus ticket.
A trip to Santa Fe Depot, San Diego, CA from Van Nuys, Metrolink Station, Los Angeles, CA is worth doing but not as a day trip with a journey time of 2h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is April.
It's helpful to compare your options as there are 3 ways to travel between Van Nuys, Metrolink Station, Los Angeles, CA and Santa Fe Depot, San Diego, CA including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA for bus company FlixBus.
Whether you can cancel your bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
Yes, the following luggage options are included when booking a bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus company: FlixBus.
Since neither Van Nuys, Metrolink Station, Los Angeles, CA nor Santa Fe Depot, San Diego, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

More options for your journey from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Here are some other resources that might have the information you need

Return journeys for buses from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA

Most popular buses to and from Santa Fe Depot, San Diego, CA and Van Nuys, Metrolink Station, Los Angeles, CA

Bus Union Station, Los Angeles, CA - Santa Fe Depot, San Diego, CA

Most popular bus connections to Santa Fe Depot, San Diego, CA

Bus Union Station, Los Angeles, CA - Santa Fe Depot, San Diego, CA
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