Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus with FlixBus

Fri, Dec 19
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Itabus
1,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
Itabus
1,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Showing times and prices for Dec 23

Cheapest price

$30

Average price

$32

Fastest journey

3 h 20 m

Average duration

4 h 10 m

Buses per day

2

Distance

204 km

Cheap tickets

The best way to find a cheap bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA will cost around $32 if you buy it on the day, but the cheapest tickets can be found for only $30.

Fast buses

Of the 2 buses that leave Van Nuys, Metrolink Station, Los Angeles, CA for Santa Fe Depot, San Diego, CA on Tue, Dec 23, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Tue, Dec 23 the direct buses cover the 204 km distance in an average of 4 h 10 m but if you time it right, some buses will get you there in just 3 h 20 m .

On Tue, Dec 23 the slowest buses will take 5 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

Greyhound
01:15PM5h00
Van Nuys, Metrolink Station, Los Angeles, CA
06:15PMSanta Fe Depot, San Diego, CA
$301One-way
0 transfers
FlixBus
08:05PM3h20
Van Nuys, Metrolink Station, Los Angeles, CA
11:25PMSanta Fe Depot, San Diego, CA
$341One-way
0 transfers

Travel Information

Compare train, bus, and flight for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Omio recommends booking the train as it is the most popular option from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €19. For those with little time consider booking a bus which can get you there in 3h 40m. The ticket price range depends on the travel mode: a bus costs an average of €19, and a flight costs an average of €46.

Distance: 126 miles (204 km)

Compare bus with

Bus
Most popular
Train
Flight

€25

Average price

Cheapest

€36

Average price

€121

Average price

4h 10m

Average total duration

Fastest

3h 40m

Onboard

+

30m

Additional time*

4h 28m

Average total duration

3h 58m

Onboard

+

30m

Additional time*

12h 53m

Average total duration

9h 53m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Live departures

Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus times

The table below shows live departures for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA buses for today, Monday, December 22. You can also manually refresh the results below to see updated bus journeys.

Last updated at 5:54 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus9:20 PM Van Nuys, Metrolink Station, Los Angeles, CA
2h35
11:55 PM Santa Fe Depot, San Diego, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Dec 23
Wed
Dec 24
Thu
Dec 25
Fri
Dec 26
Sat
Dec 27
Sun
Dec 28
Mon
Dec 29

Journey information

Overview: Bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

USAUSA
USAUSA
Icon of bus

Buses from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA run on average 18 times per day, taking around 3h 40m. Cheap bus tickets for this journey start at $24 (€19) if you book in advance.

There are 14 buses per day. The earliest bus runs at 12:50, the last at 21:45. The fastest bus covers the 126 miles (204 km) distance in 2h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
126 miles (204 km)
Average bus duration
3h 40m
Cheapest ticket price
$24 (€19)
Buses per day
18
Direct buses
14
Fastest bus
2h 35m
First bus
12:50
Last bus
21:45
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CAYou can travel by bus between Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with FlixBus for as low as $24 (€19). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
2h 35m
Cheapest Price
$28 (€22)
FlixBus frequency
27 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

FAQs: Bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

Find answers to the most common questions about traveling from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA can start from as little as $32 (€26) when you book in advance. The average bus ticket price for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is $32 (€26); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is 5 h 25 min   to travel the 126 mile (204 km) long trip, with around there are 9 buses per day. Journey times can vary on weekends and holidays.
The bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA leaves at 10: 40PM. Plan your trip with the Journey Planner   from Omio.
There are 9 buses a day from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA which require at least one change with FlixBus or Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA, you can count on FlixBus or Greyhound for the best way to get you to Santa Fe Depot, San Diego, CA. You can also check all possible bus companies who offer a service from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA and compare the amenities they offer before buying a bus ticket.
The cheapest month for a bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is October.
You have options as you can travel from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA 3 different ways: train, bus or flight.
Yes, the following accessibility options are available when taking the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA for bus companies FlixBus and Greyhound.
Yes, bikes are allowed on board the bus with bus companies FlixBus and Greyhound.
Whether you can cancel your bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA depends on the bus providers:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

To find the cheapest bus tickets for your trip from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
    Yes, the following luggage options are included when booking a bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    • Greyhound
      • $15 per additional bag.
    Yes, you can bring your pet on the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus providers: FlixBus and Greyhound
    Yes, there are USB plugs on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus providers: FlixBus and Greyhound.
    Yes, there is Wifi on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus providers: FlixBus and Greyhound.

    More options for your journey from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA

    Here are some other resources that might have the information you need

    Return journeys for buses from Santa Fe Depot, San Diego, CA to Van Nuys, Metrolink Station, Los Angeles, CA

    Most popular buses to and from Santa Fe Depot, San Diego, CA and Van Nuys, Metrolink Station, Los Angeles, CA

    Bus Union Station, Los Angeles, CA - Santa Fe Depot, San Diego, CA
    Bus Santa Ana Station, Santa Ana, CA - Santa Fe Depot, San Diego, CA
    HomeBusesBuses in USAVan Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus

    The Omio App Makes Travel Planning Easy

    We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

    ios-badge
    android-badge
    Hand With Phone