2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
Showing times, prices and bookable tickets for Nov 03
- Cheapest price on Nov 03
- $50
- Average ticket price on Nov 03
- $60
- Fastest journey on Nov 03
- 2 h 45 m
- Average journey duration on Nov 03
- 2 h 53 m
- Buses on Nov 03
- 8
- Distance
- 204 km
Cheap tickets
The best way to find a cheap bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA will cost around $60 if you buy it on the day, but the cheapest tickets can be found for only $50.
Fast buses
On Tue, Nov 03, we found 8 buses from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA, including 8 direct services.
On Tue, Nov 03 the direct buses cover the 204 km distance in an average of 2 h 53 m but if you time it right, some buses will get you there in just 2 h 45 m .
On Tue, Nov 03 the slowest buses will take 3 h 19 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
010:00 AM 2h49 Van Nuys, Metrolink Station, Los Angeles, CA 12:49 PM Santa Fe Depot, San Diego, CA $50 1 One-way 0 transfers- 0
8:00 PM 2h49 Van Nuys, Metrolink Station, Los Angeles, CA 10:49 PM Santa Fe Depot, San Diego, CA $50 1 One-way 0 transfers 
02:15 AM 2h45 Van Nuys, Metrolink Station, Los Angeles, CA 5:00 AM Santa Fe Depot, San Diego, CA $50 1 One-way 0 transfers- 0
1:30 PM 4h05 Van Nuys, Metrolink Station, Los Angeles, CA 5:35 PM Santa Fe Depot, San Diego, CA $50 1 One-way 0 transfers - 0
2:15 PM 2h45 Van Nuys, Metrolink Station, Los Angeles, CA 5:00 PM Santa Fe Depot, San Diego, CA $50 1 One-way 0 transfers
- 0
2:15 AM 2h45 Van Nuys, Metrolink Station, Los Angeles, CA 5:00 AM Santa Fe Depot, San Diego, CA $50 1 One-way 0 transfers - 0
2:15 PM 2h45 Van Nuys, Metrolink Station, Los Angeles, CA 5:00 PM Santa Fe Depot, San Diego, CA $50 1 One-way 0 transfers - 0
10:00 AM 2h49 Van Nuys, Metrolink Station, Los Angeles, CA 12:49 PM Santa Fe Depot, San Diego, CA $50 1 One-way 0 transfers - 0
8:00 PM 2h49 Van Nuys, Metrolink Station, Los Angeles, CA 10:49 PM Santa Fe Depot, San Diego, CA $50 1 One-way 0 transfers - 0
7:30 AM 3h19 Van Nuys, Metrolink Station, Los Angeles, CA 10:49 AM Santa Fe Depot, San Diego, CA $77 1 One-way 0 transfers
Journey information
Overview: Bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
USAUSA
Buses from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA run on average 12 times per day, taking around 3h 23m. Cheap bus tickets for this journey start at $28 (€23) if you book in advance.
There are 11 buses per day. The earliest bus runs at 01:30, the last at 22:25. The fastest bus covers the 126 miles (204 km) distance in 1h 49m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 126 miles (204 km) |
Average bus duration 3h 23m |
Cheapest ticket price $28 (€23) |
Buses per day 12 |
Direct buses 11 |
Fastest bus 1h 49m |
First bus 1:30 AM |
Last bus 10:25 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Apr - Jun |
Busiest Day Thu |
Least Busy Day Thu |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
Cheap bus tickets from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA can start from as little as $28 (€23) when you book in advance. The average bus ticket price for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA is $50 (€42) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA leaves at 1:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA leaves at 10:25 PM.
Yes, there are 11 direct buses a day from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with Futura Net, FlixBus, Tufesa Internacional, Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:30AM | Arrival Time 04:45AM | Duration 3h15 | Departure days Fri, Sat, Sun | Cheapest price $26 |
Operator Tufesa Internacional | Departure Time 02:15AM | Arrival Time 05:00AM | Duration 2h45 | Departure days Tue, Wed | Cheapest price $50 |
Operator FlixBus | Departure Time 02:30AM | Arrival Time 05:45AM | Duration 3h15 | Departure days Mon | Cheapest price $28 |
Operator Amtrak | Departure Time 05:09AM | Arrival Time 09:20AM | Duration 4h11 | Departure days Sat | Cheapest price $42 |
Operator Futura Net | Departure Time 05:15AM | Arrival Time 08:34AM | Duration 3h19 | Departure days Tue, Wed | Cheapest price $50 |
Operator Futura Net | Departure Time 07:30AM | Arrival Time 10:49AM | Duration 3h19 | Departure days Tue, Wed | Cheapest price $50 |
Operator Futura Net | Departure Time 10:00AM | Arrival Time 12:49PM | Duration 2h49 | Departure days Tue, Wed | Cheapest price $50 |
Operator Tufesa Internacional | Departure Time 01:30PM | Arrival Time 05:35PM | Duration 4h05 | Departure days Tue | Cheapest price $50 |
Operator Futura Net | Departure Time 01:30PM | Arrival Time 03:49PM | Duration 2h19 | Departure days Wed | Cheapest price $50 |
Operator Tufesa Internacional | Departure Time 02:15PM | Arrival Time 05:00PM | Duration 2h45 | Departure days Tue, Wed | Cheapest price $50 |
Operator FlixBus | Departure Time 02:20PM | Arrival Time 05:40PM | Duration 3h20 | Departure days Mon | Cheapest price $34 |
Operator Futura Net | Departure Time 04:00PM | Arrival Time 07:19PM | Duration 3h19 | Departure days Tue, Wed | Cheapest price $77 |
Operator FlixBus | Departure Time 06:15PM | Arrival Time 10:55PM | Duration 4h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $23 |
Operator FlixBus | Departure Time 06:55PM | Arrival Time 10:10PM | Duration 3h15 | Departure days Thu | Cheapest price $24 |
Operator Amtrak | Departure Time 07:07PM | Arrival Time 11:55PM | Duration 4h48 | Departure days Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 07:15PM | Arrival Time 11:55PM | Duration 4h40 | Departure days Fri, Sat | Cheapest price $25 |
Operator Futura Net | Departure Time 08:00PM | Arrival Time 10:49PM | Duration 2h49 | Departure days Tue, Wed | Cheapest price $50 |
Live departures
Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus times
The table below shows live departures for Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA buses for tomorrow, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 0 | 2:15 AM Van Nuys, Metrolink Station, Los Angeles, CA | 2h45 | 5:00 AM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
| 0 | 5:15 AM Van Nuys, Metrolink Station, Los Angeles, CA | 3h19 | 8:34 AM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
| 0 | 7:30 AM Van Nuys, Metrolink Station, Los Angeles, CA | 3h19 | 10:49 AM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
| 0 | 10:00 AM Van Nuys, Metrolink Station, Los Angeles, CA | 2h49 | 12:49 PM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
| 0 | 1:30 PM Van Nuys, Metrolink Station, Los Angeles, CA | 4h05 | 5:35 PM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
| 0 | 2:15 PM Van Nuys, Metrolink Station, Los Angeles, CA | 2h45 | 5:00 PM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA buses with Omio?
Futura Net as well as FlixBus, Tufesa Internacional, Greyhound and more offer buses services from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
Omio is the only official third party seller for Futura Net tickets.
Why book with Omio vs Futura Net?
- Compare with other providers: On Omio, you can not only buy tickets for Futura Net, but also compare tickets for the likes of FlixBus, Tufesa Internacional or Greyhound to find the best option for your trip from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Futura Net with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
Bus providers: FlixBus, Futura Net, Tufesa Internacional, Greyhound from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CAYou can travel by bus between Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with FlixBus, Futura Net, Tufesa Internacional, Greyhound for as low as $28 (€23). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
2h 10m
Cheapest FlixBus Price
$28 (€23)
FlixBus frequency
11 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
3h 25m
Cheapest Greyhound Price
$29 (€24)
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Futura Net
Luggage & cancellation policy
Average Futura Net Duration
1h 49m
Cheapest Futura Net Price
$48 (€40)
Futura Net frequency
6 a day
Tufesa Internacional
Luggage & cancellation policy
Average Tufesa Internacional Duration
2h 45m
Cheapest Tufesa Internacional Price
$49 (€41)
Tufesa Internacional frequency
2 a day
Companies, tickets, and onboard amenities between Van Nuys, Metrolink Station, Los Angeles, CA and Santa Fe Depot, San Diego, CA
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA, you can count on Futura Net, FlixBus, Tufesa Internacional, Greyhound for the best way to get you to Santa Fe Depot, San Diego, CA. You can also check all possible bus companies who offer a service between Van Nuys, Metrolink Station, Los Angeles, CA and Santa Fe Depot, San Diego, CA and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA for bus company FlixBus, Greyhound.
Whether you can cancel your bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA.
Yes, the following luggage options are included when booking a bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA with the following bus company: FlixBus, Greyhound.
FAQs: Bus from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
Find answers to the most common questions about traveling from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 3 ways to travel between Van Nuys, Metrolink Station, Los Angeles, CA and Santa Fe Depot, San Diego, CA including taking a train, bus, and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
More options for your journey from Van Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA
Here are some other resources that might have the information you need
Most popular buses to and from Santa Fe Depot, San Diego, CA and Van Nuys, Metrolink Station, Los Angeles, CA
Most popular bus connections to Santa Fe Depot, San Diego, CA
HomeBusesBuses in USAVan Nuys, Metrolink Station, Los Angeles, CA to Santa Fe Depot, San Diego, CA bus
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
