Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA bus with FlixBus

Thu, May 07
+ Add return
FlixBus
Greyhound
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
FlixBus
Greyhound
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA

Showing times and prices for May 07

Cheapest price

$22

Average price

$23

Fastest journey

1 h 15 m

Average duration

1 h 23 m

Buses per day

2

Distance

117 km

Cheap tickets

The best way to find a cheap bus ticket from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA will cost around $23 if you buy it on the day, but the cheapest tickets can be found for only $22.

Fast buses

Of the 2 buses that leave Irvine Transportation Center, Irvine, CA for Santa Fe Depot, San Diego, CA on Thu, May 07, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Thu, May 07 the direct buses cover the 117 km distance in an average of 1 h 23 m but if you time it right, some buses will get you there in just 1 h 15 m .

On Thu, May 07 the slowest buses will take 1 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBus
    8:10 PM1h30
    Irvine Transportation Center, Irvine, CA
    9:40 PMSanta Fe Depot, San Diego, CA
    $221One-way
    0 transfers
  • FlixBus
    4:30 AM1h15
    Irvine Transportation Center, Irvine, CA
    5:45 AMSanta Fe Depot, San Diego, CA
    $231One-way
    0 transfers

Travel Information

Compare train and bus for Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA

Omio recommends booking the train as it is the most popular option from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $14. For those with little time consider booking a train which can get you there in 1h 53m. The ticket price range depends on the travel mode: a bus costs an average of $14, and a train costs an average of $30.

Distance: 72 miles (117 km)

Compare bus with

Bus
Most popular
Train

$25

Average price

Cheapest

$31

Average price

2h 34m

Average total duration

2h 4m

Onboard

+

30m

Additional time*

2h 23m

Average total duration

Fastest

1h 53m

Onboard

+

30m

Additional time*

FlixBus

Most popular bus company

Amtrak

Most popular train company

Direct Options

Direct Options

Live departures

Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA bus times

The table below shows live departures for Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA buses for today, Wednesday, May 6. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus10:35 PM Irvine Transportation Center, Irvine, CA
1h50
12:25 AM Santa Fe Depot, San Diego, CA0 transfersDirect
Thursday, May 7
meinfernbus_flixbus4:30 AM Irvine Transportation Center, Irvine, CA
1h15
5:45 AM Santa Fe Depot, San Diego, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Thu
May 07
Fri
May 08
Sat
May 09
Sun
May 10
Mon
May 11
Tue
May 12
Wed
May 13
Thu
May 14
Fri
May 15
Sat
May 16
Sun
May 17
Mon
May 18
Tue
May 19
Wed
May 20
Thu
May 21
Fri
May 22
Sat
May 23
Sun
May 24
Mon
May 25
Tue
May 26
Wed
May 27

Why should you book Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA buses with Omio?

FlixBus as well as Greyhound offer buses services from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA.
Omio is an official ticket reseller for all your travel options from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA.
  • Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA.

Journey information

Overview: Bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA

USAUSA
USAUSA
Icon of bus

Buses from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA run on average 14 times per day, taking around 2h 4m. Cheap bus tickets for this journey start at $14 (€11) if you book in advance.

There are 13 buses per day. The earliest bus runs at 04:20, the last at 22:35. The fastest bus covers the 72 miles (117 km) distance in 1h 15m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
72 miles (117 km)
Average bus duration
2h 4m
Cheapest ticket price
$14 (€11)
Buses per day
14
Direct buses
13
Fastest bus
1h 15m
First bus
4:20 AM
Last bus
10:35 PM
Cheapest Month
Feb
Cheapest Day
Wed
High Season
Jan - Mar
Low Season
Jul - Sep
Busiest Day
Fri
Least Busy Day
Wed
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Greyhound from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CAYou can travel by bus between Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA with FlixBus, Greyhound for as low as $14 (€11). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
1h 15m
Cheapest Price
$14 (€11)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
1h 45m
Cheapest Price
$45 (€36)
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA

Find answers to the most common questions about traveling from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA can start from as little as $14 (€11) when you book in advance. The average bus ticket price for Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA is $25 (€20) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA is 1h 15m to travel the 72 miles (117 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA leaves at 4:20 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA leaves at 10:35 PM.
Yes, there are 13 direct buses a day from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA with . Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA, you can count on FlixBus, Greyhound for the best way to get you to Santa Fe Depot, San Diego, CA. You can also check all possible bus companies who offer a service between Irvine Transportation Center, Irvine, CA and Santa Fe Depot, San Diego, CA and compare the amenities they offer before buying a bus ticket.
A day trip to Santa Fe Depot, San Diego, CA from Irvine Transportation Center, Irvine, CA is worth doing with a journey time of 1h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA is February.
It's helpful to compare your options as there are 2 ways to travel between Irvine Transportation Center, Irvine, CA and Santa Fe Depot, San Diego, CA including taking a train and bus.
Yes, the following accessibility options are available when taking the bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA for bus company FlixBus, Greyhound.
Whether you can cancel your bus ticket from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA.
Yes, the following luggage options are included when booking a bus ticket from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA with the following bus company: FlixBus, Greyhound.
Since neither Irvine Transportation Center, Irvine, CA nor Santa Fe Depot, San Diego, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

Most popular bus connections from Irvine Transportation Center, Irvine, CA

Bus Irvine Transportation Center, Irvine, CA - Old Town Station, San Diego, CA

More options for your journey from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA

Here are some other resources that might have the information you need

Return journeys for buses from Santa Fe Depot, San Diego, CA to Irvine Transportation Center, Irvine, CA
Trains from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA

Most popular bus connections to Santa Fe Depot, San Diego, CA

Bus Union Station, Los Angeles, CA - Santa Fe Depot, San Diego, CA
HomeBusesBuses in USAIrvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone