The cheapest and fastest buses from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA
- Cheapest price on Nov 05
- €16
- Average ticket price on Nov 05
- €18
- Fastest journey on Nov 05
- 1 h 15 m
- Average journey duration on Nov 05
- 1 h 33 m
- Buses on Nov 05
- 4
- Distance
- 117 km
The best way to find a cheap bus ticket from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA will cost around €18 if you buy it on the day, but the cheapest tickets can be found for only €16.
On Thu, Nov 05, we found 4 buses from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA, including 4 direct services.
On Thu, Nov 05 the direct buses cover the 117 km distance in an average of 1 h 33 m but if you time it right, some buses will get you there in just 1 h 15 m .
On Thu, Nov 05 the slowest buses will take 1 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

4:30 AM 1h15 Irvine Transportation Center, Irvine, CA 5:45 AM Santa Fe Depot, San Diego, CA €16 1 One-way 0 transfers
3:30 AM 1h15 Irvine Transportation Center, Irvine, CA 4:45 AM Santa Fe Depot, San Diego, CA €17 1 One-way 0 transfers
10:35 PM 1h50 Irvine Transportation Center, Irvine, CA 12:25 AM Santa Fe Depot, San Diego, CA €19 1 One-way 0 transfers
9:35 PM 1h50 Irvine Transportation Center, Irvine, CA 11:25 PM Santa Fe Depot, San Diego, CA €19 1 One-way 0 transfers

4:30 AM 1h15 Irvine Transportation Center, Irvine, CA 5:45 AM Santa Fe Depot, San Diego, CA €16 1 One-way 0 transfers
3:30 AM 1h15 Irvine Transportation Center, Irvine, CA 4:45 AM Santa Fe Depot, San Diego, CA €17 1 One-way 0 transfers
10:35 PM 1h50 Irvine Transportation Center, Irvine, CA 12:25 AM Santa Fe Depot, San Diego, CA €19 1 One-way 0 transfers
9:35 PM 1h50 Irvine Transportation Center, Irvine, CA 11:25 PM Santa Fe Depot, San Diego, CA €19 1 One-way 0 transfers
Journey information
Overview: Bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA
Buses from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA run on average 11 times per day, taking around 1h 30m. Cheap bus tickets for this journey start at €15 if you book in advance.
There are 11 buses per day. The earliest bus runs at 02:31, the last at 23:14. The fastest bus covers the 72 miles (117 km) distance in 48m.
Plan this route
Journey facts
- Distance72 miles (117 km)
- Average bus duration1h 30m
- Cheapest ticket price€15
- Buses per day11
- Direct buses11
- Fastest bus48m
- First bus2:31 AM
- Last bus11:14 PM
- Cheapest MonthAug
- Cheapest DayThu
- High SeasonApr - Jun
- Low SeasonJul - Sep
- Busiest DayMon
- Least Busy DayThu
- Best time to book1 day
Understand & plan this route
Explore this journey
Book with confidence
Frequently asked questions about your Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA.
Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:30AM | Arrival Time 04:45AM | Duration 1h15 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price €14 |
Operator FlixBus | Departure Time 04:30AM | Arrival Time 05:45AM | Duration 1h15 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price €16 |
Operator Greyhound | Departure Time 05:05AM | Arrival Time 06:50AM | Duration 1h45 | Departure days Mon | Cheapest price €33 |
Operator Amtrak | Departure Time 05:25AM | Arrival Time 07:25AM | Duration 2h00 | Departure days Mon | Cheapest price €25 |
Operator Infobus | Departure Time 05:31AM | Arrival Time 06:19AM | Duration 0h48 | Departure days Sat | Cheapest price €39 |
Operator Futura Net | Departure Time 06:29AM | Arrival Time 08:34AM | Duration 2h05 | Departure days Sat | Cheapest price €65 |
Operator Futura Net | Departure Time 06:46AM | Arrival Time 07:34AM | Duration 0h48 | Departure days Sat | Cheapest price €36 |
Operator Futura Net | Departure Time 08:44AM | Arrival Time 09:49AM | Duration 1h05 | Departure days Sat | Cheapest price €36 |
Operator Futura Net | Departure Time 09:01AM | Arrival Time 10:19AM | Duration 1h18 | Departure days Sat | Cheapest price €42 |
Operator Futura Net | Departure Time 11:14AM | Arrival Time 01:19PM | Duration 2h05 | Departure days Sat | Cheapest price €65 |
Operator Futura Net | Departure Time 11:31AM | Arrival Time 12:49PM | Duration 1h18 | Departure days Sat | Cheapest price €42 |
Operator Futura Net | Departure Time 02:44PM | Arrival Time 03:49PM | Duration 1h05 | Departure days Sat | Cheapest price €36 |
Operator Futura Net | Departure Time 03:01PM | Arrival Time 04:19PM | Duration 1h18 | Departure days Sat | Cheapest price €42 |
Operator Futura Net | Departure Time 05:14PM | Arrival Time 07:19PM | Duration 2h05 | Departure days Sat | Cheapest price €65 |
Operator Futura Net | Departure Time 05:31PM | Arrival Time 07:19PM | Duration 1h48 | Departure days Sat | Cheapest price €65 |
Operator FlixBus | Departure Time 07:10PM | Arrival Time 08:40PM | Duration 1h30 | Departure days Mon, Thu, Fri | Cheapest price €12 |
Operator FlixBus | Departure Time 08:10PM | Arrival Time 09:40PM | Duration 1h30 | Departure days Mon, Thu | Cheapest price €12 |
Operator Futura Net | Departure Time 09:14PM | Arrival Time 10:19PM | Duration 1h05 | Departure days Sat | Cheapest price €36 |
Operator Futura Net | Departure Time 09:31PM | Arrival Time 10:19PM | Duration 0h48 | Departure days Sat | Cheapest price €36 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 11:25PM | Duration 1h50 | Departure days Tue, Wed | Cheapest price €19 |
Operator FlixBus | Departure Time 10:35PM | Arrival Time 12:25AM | Duration 1h50 | Departure days Wed | Cheapest price €19 |
Live departures
Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA bus times
The table below shows live departures for Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:35 PM Irvine Transportation Center, Irvine, CA | 1h50 | 11:25 PM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
| Wednesday, November 4 | |||||
![]() | 3:30 AM Irvine Transportation Center, Irvine, CA | 1h15 | 4:45 AM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
![]() | 4:30 AM Irvine Transportation Center, Irvine, CA | 1h15 | 5:45 AM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA buses with Omio?
Why book with Omio vs Futura Net?
- Compare with other providers: On Omio, you can not only buy tickets for Futura Net, but also compare tickets for the likes of FlixBus, Infobus or Greyhound to find the best option for your trip from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Futura Net with all available travel options, which are train and bus to ensure you get the best deal for traveling from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA.
Bus companies
Bus companies from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA
Buses from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA with Futura Net, FlixBus, and Infobus. Overnight buses available on this route with FlixBus and Greyhound. Use the details below to compare onboard facilities.
FlixBus
Infobus
Greyhound
Futura Net
Companies, tickets, and onboard amenities between Irvine Transportation Center, Irvine, CA and Santa Fe Depot, San Diego, CA
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
FAQs: Bus from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA
Find answers to the most common questions about traveling from Irvine Transportation Center, Irvine, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.

