Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA bus with Greyhound

Fri, Dec 19
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Greyhound
FlixBus
Infobus
Alsa
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1,000+ travel companies
Greyhound
FlixBus
Infobus
Alsa
BlaBlaCar Bus
1,000+ travel companies
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The cheapest and fastest buses from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA

Showing times and prices for Dec 23

Cheapest price

$27

Average price

$27

Fastest journey

2 h 20 m

Average duration

2 h 20 m

Buses per day

1

Distance

132 km

Cheap tickets

The best way to find a cheap bus ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA will cost around $27 if you buy it on the day, but the cheapest tickets can be found for only $27.

Fast buses

Of the 1 buses that leave Santa Ana Station, Santa Ana, CA for Santa Fe Depot, San Diego, CA on Tue, Dec 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Tue, Dec 23 the direct buses cover the 132 km distance in an average of 2 h 20 m but if you time it right, some buses will get you there in just 2 h 20 m .

On Tue, Dec 23 the slowest buses will take 2 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

FlixBus
09:05PM2h20
Santa Ana Station, Santa Ana, CA
11:25PMSanta Fe Depot, San Diego, CA
$271One-way
0 transfers

Santa Ana Station, Santa Ana, CA - Santa Fe Depot, San Diego, CACompare Greyhound, FlixBus, Infobus

greyhound
$24
1h 50m
5 a day
Power plugs
Wifi
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Seat reservation
See Greyhound buses
meinfernbus_flixbus
$19
1h 10m
14 a day
Power plugs
Wifi
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Seat reservation
See FlixBus buses
ams_infobus
$40
1h 20m
16 a day
Power plugs
Wifi
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Seat reservation
See Infobus buses

Travel Information

Compare bus and train for Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA

Omio recommends booking the train as it is the most popular option from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €13. For those with little time consider booking a bus which can get you there in 1h 56m. The ticket price range depends on the travel mode: a bus costs an average of €13, and a train costs an average of €26.

Distance: 82 miles (132 km)

Compare bus with

Bus
Most popular
Train

€18

Average price

Cheapest

€26

Average price

2h 26m

Average total duration

Fastest

1h 56m

Onboard

+

30m

Additional time*

2h 34m

Average total duration

2h 4m

Onboard

+

30m

Additional time*

Greyhound

Most popular bus company

Amtrak

Most popular train company

Direct Options

Direct Options

Live departures

Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA bus times

The table below shows live departures for Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA buses for today, Monday, December 22. You can also manually refresh the results below to see updated bus journeys.

Last updated at 8:00 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbus11:55 PM Santa Ana Station, Santa Ana, CA
2h00
1:55 AM Santa Fe Depot, San Diego, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA by bus or train

Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Dec 23
Wed
Dec 24
Thu
Dec 25
Fri
Dec 26
Sat
Dec 27
Sun
Dec 28
Mon
Dec 29

Journey information

Overview: Bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA

USAUSA
USAUSA
Icon of bus

Buses from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA run on average 17 times per day, taking around 1h 56m. Cheap bus tickets for this journey start at $16 (€13) if you book in advance.

There are 16 buses per day. The earliest bus runs at 14:10, the last at 23:55. The fastest bus covers the 82 miles (132 km) distance in 1h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
82 miles (132 km)
Average bus duration
1h 56m
Cheapest ticket price
$16 (€13)
Buses per day
17
Direct buses
16
Fastest bus
1h 10m
First bus
14:10
Last bus
23:55
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus, Infobus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CAYou can travel by bus between Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA with Greyhound, FlixBus, Infobus for as low as $16 (€13). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
1h 10m
Cheapest Price
$19 (€15)
FlixBus frequency
14 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Infobus

About
Infobus is an international IT company that operates as an online service for finding and purchasing bus, train, and plane tickets, rather than being a bus company itself. Established in 2002, Infobus acts as an intermediary between passengers and various transport carriers, particularly helping smaller bus companies offer online booking services. They utilize their own "BusSystem" to manage routes and ticket sales globally. Infobus covers over 30 countries and 300 cities, offering a wide range of routes and daily departures. While amenities can vary by carrier, Infobus aims to provide affordable and convenient travel with features like online booking, 24/7 support, and prompt notifications.
Luggage & cancellation policy
Average Duration
1h 20m
Cheapest Price
$40 (€32)
Infobus frequency
16 a day
Luggage included
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Transport for wheelchairs and mobility aids.
Bikes
Bikes are allowed; may require prior reservation and an additional fee.
Pets
Small pets allowed in carriers; larger pets may require a separate ticket.
Learn more about Infobus

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
1h 50m
Cheapest Price
$24 (€19)
Greyhound frequency
5 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA

Find answers to the most common questions about traveling from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA can start from as little as $23 (€18) when you book in advance. The average bus ticket price for Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA is $30 (€24); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA is on average 1 h 15 min   for the 81 mile (131 km) long journey, but the time it takes to go to Santa Fe Depot, San Diego, CA from Santa Ana Station, Santa Ana, CA by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA leaves at 3: 10PM. Plan your trip with the Journey Planner   from Omio.
The last bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA leaves at 11: 25PM.
Yes, it is possible to travel from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA without having to change trains with FlixBus or Greyhound. There are 11 direct buses from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA each day. There may be fewer direct services available on weekends or holidays.
Take the Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA bus with FlixBus, Greyhound or Infobus. However, it's always good to check out all possible bus companies for the trip to Santa Fe Depot, San Diego, CA from Santa Ana Station, Santa Ana, CA as there might be differences in the amenities they offer.
A day trip to Santa Fe Depot, San Diego, CA from Santa Ana Station, Santa Ana, CA is worth doing with a journey time of 1 h 15 min each way. Check with Omio app   the best way to travel.
The cheapest month for a bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA is October.
You have options as you can travel between Santa Ana Station, Santa Ana, CA and Santa Fe Depot, San Diego, CA 2 different ways: train or bus.
Yes, the following accessibility options are available when taking the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • Infobus
    • Assistance
    • Priority seating
    • Transport for wheelchairs and mobility aids.
Yes, there are bathrooms on board the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA for bus companies FlixBus, Greyhound and Infobus.
Yes, bikes are allowed on board the bus with bus companies FlixBus, Greyhound and Infobus.
Whether you can cancel your bus ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • Infobus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.

To find the cheapest bus tickets for your trip from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.

    • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA.
    Yes, the following luggage options are included when booking a bus ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    • Infobus
      • One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
    Yes, the following additional luggage options are available when booking a bus ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    • Greyhound
      • $15 per additional bag.
    • Infobus
      • 10€ per additional bag.
    Yes, you can bring your pet on the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    • Infobus
      • Small pets allowed in carriers
      • Larger pets may require a separate ticket.
    You can reserve your seat on the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA with the following bus companies: FlixBus, Greyhound and Infobus
    Yes, there are USB plugs on board the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA with the following bus companies: FlixBus, Greyhound and Infobus.
    Yes, there is Wifi on board the bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA with the following bus companies: FlixBus, Greyhound and Infobus.

    Most popular bus connections to Santa Fe Depot, San Diego, CA

    Bus Union Station, Los Angeles, CA - Santa Fe Depot, San Diego, CA
    HomeBusesBuses in USASanta Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA bus

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