4.9
4.6The cheapest and fastest buses from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA
Cheapest price
$16
Average price
$43
Fastest journey
1 h 5 m
Average duration
1 h 7 m
Buses per day
40
Distance
132 km
The best way to find a cheap bus ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA will cost around $43 if you buy it on the day, but the cheapest tickets can be found for only $16.
Of the 40 buses that leave Santa Ana Station, Santa Ana, CA for Santa Fe Depot, San Diego, CA on Thu, May 14, 40 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 14 the direct buses cover the 132 km distance in an average of 1 h 7 m but if you time it right, some buses will get you there in just 1 h 5 m .
On Thu, May 14 the slowest buses will take 1 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus12:10 PM2h00Irvine, West Peltason Dr (UCI Crawford Hall), CA2:10 PMSan Diego, Congress Street (Old Town Park), CA$161One-way0 transfers- FlixBus12:10 PM1h30Irvine, West Peltason Dr (UCI Crawford Hall), CA1:40 PMLa Jolla, UCSD Health La Jolla Station, CA$161One-way0 transfers
- FlixBus8:30 PM1h45Santa Ana, E Santa Ana Blvd (Train Station)10:15 PMSan Diego, West Harbor Drive (The Headquarters at Seaport District), CA$201One-way0 transfers
- FlixBus8:30 PM1h15Santa Ana, E Santa Ana Blvd (Train Station)9:45 PMLa Jolla, UCSD Health La Jolla Station, CA$201One-way0 transfers
- FlixBus12:10 PM2h00Santa Ana Station, Santa Ana, CA2:10 PMSan Diego, Congress Street (Old Town Park), CA$201One-way0 transfers
010:44 AM1h05Tustin, CA11:49 AMSan Diego, CA$471One-way0 transfers- 06:29 AM1h05Tustin, CA7:34 AMSan Diego, CA$491One-way0 transfers
- 07:14 PM1h05Tustin, CA8:19 PMSan Diego, CA$491One-way0 transfers
- 010:39 AM1h10Santa Ana, CA11:49 AMSan Diego, CA$491One-way0 transfers
- 06:24 AM1h10Santa Ana, CA7:34 AMSan Diego, CA$491One-way0 transfers
Travel Information
Compare train and bus for Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA
Omio recommends booking the train as it is the most popular option from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $16. For those with little time consider booking a bus which can get you there in 1h 56m. The ticket price range depends on the travel mode: a bus costs an average of $16, and a train costs an average of $32.
Distance: 82 miles (132 km)
Compare bus with
| Bus | Most popular Train | Driving |
|---|---|---|
$24 Average price Cheapest | $33 Average price | $19 Average price (fuel + tolls) |
2h 26m Average total duration Fastest 1h 56m Onboard + 30m Additional time* | 2h 34m Average total duration 2h 4m Onboard + 30m Additional time* | 1h 24m Average total duration (door-to-door) |
 Most popular bus company |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA:
A bus is $9 (€7) less than a train for this route with tickets for a train from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA costing on average $33 (€26).
Other travel options to Santa Fe Depot, San Diego, CA take longer:
Train takes on average 2h 4m.
You'll arrive about -1h -32m sooner (1h 56m by bus vs 1h 24m by car) and save roughly $-5.25 (€-4.20) compared to fuel and tolls ($24 (€20) vs $19 (€15)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Greyhound, FlixBus, Infobus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Live departures
Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA bus times
The table below shows live departures for Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA buses for today, Wednesday, May 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 5:05 AM Santa Ana Station, Santa Ana, CA | 1h45 | 6:50 AM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
| 9:35 PM Santa Ana Station, Santa Ana, CA | 1h50 | 11:25 PM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
| 10:35 PM Santa Ana Station, Santa Ana, CA | 1h50 | 12:25 AM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
| Thursday, May 14 | |||||
| 3:30 AM Santa Ana Station, Santa Ana, CA | 1h15 | 4:45 AM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
| 4:30 AM Santa Ana Station, Santa Ana, CA | 1h15 | 5:45 AM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 14
May 15
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May 22
May 23
May 24
May 25
May 26
May 27
Why should you book Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus or Infobus to find the best option for your trip from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train and bus to ensure you get the best deal for traveling from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA.
Why book with Omio over Wanderu, Trainline or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus or Infobus to find the best option for your trip from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA.
Journey information
Overview: Bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA
USAUSA
Buses from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA run on average 19 times per day, taking around 1h 56m. Cheap bus tickets for this journey start at $16 (€12) if you book in advance.
There are 17 buses per day. The earliest bus runs at 02:14, the last at 22:35. The fastest bus covers the 82 miles (132 km) distance in 1h 5m.
Distance 82 miles (132 km) |
Average bus duration 1h 56m |
Cheapest ticket price $16 (€12) |
Buses per day 19 |
Direct buses 17 |
Fastest bus 1h 5m |
First bus 2:14 AM |
Last bus 10:35 PM |
Cheapest Month Nov |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Mon |
Bus providers: Greyhound, FlixBus, Infobus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CAYou can travel by bus between Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA with Greyhound, FlixBus, Infobus for as low as $16 (€12). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
Greyhound
FAQs: Bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA
Find answers to the most common questions about traveling from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
Most popular bus connections from Santa Ana Station, Santa Ana, CA
Most popular buses to and from Santa Fe Depot, San Diego, CA and Santa Ana Station, Santa Ana, CA
Most popular bus connections to Santa Fe Depot, San Diego, CA
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