The cheapest and fastest buses from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA
Cheapest price
$23
Average price
$30
Fastest journey
1 h 15 m
Average duration
1 h 28 m
Buses per day
12
Distance
132 km
The best way to find a cheap bus ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA will cost around $30 if you buy it on the day, but the cheapest tickets can be found for only $23.
Of the 12 buses that leave Santa Ana Station, Santa Ana, CA for Santa Fe Depot, San Diego, CA on Fri, Nov 07, 12 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct buses cover the 132 km distance in an average of 1 h 28 m but if you time it right, some buses will get you there in just 1 h 15 m .
On Fri, Nov 07 the slowest buses will take 1 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
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FlixBusTravel Information
Compare bus and train for Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA
Omio recommends booking the train as it is the most popular option from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from €13. For those with little time consider booking a bus which can get you there in 1h 56m. The ticket price range depends on the travel mode: a bus costs an average of €13, and a train costs an average of €26.
Distance: 82 miles (132 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€18 Average price Cheapest | €26 Average price |
2h 26m Average total duration Fastest 1h 56m Onboard + 30m Additional time* | 2h 34m Average total duration 2h 4m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 09:40AM | Arrival Time 11:45AM | Duration 2h05 | Departure days Mon, Fri | Cheapest price $37 |
Operator Greyhound | Departure Time 10:00AM | Arrival Time 11:45AM | Duration 1h45 | Departure days Mon, Fri | Cheapest price $37 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 01:40PM | Duration 1h30 | Departure days Mon, Fri | Cheapest price $23 |
Operator FlixBus | Departure Time 02:35PM | Arrival Time 03:55PM | Duration 1h20 | Departure days Mon, Fri | Cheapest price $24 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 04:55PM | Duration 1h30 | Departure days Fri | Cheapest price $25 |
Operator FlixBus | Departure Time 08:30PM | Arrival Time 09:45PM | Duration 1h15 | Departure days Mon, Fri | Cheapest price $23 |
Operator Greyhound | Departure Time 09:40PM | Arrival Time 11:50PM | Duration 2h10 | Departure days Mon, Fri | Cheapest price $36 |
Operator Greyhound | Departure Time 10:05PM | Arrival Time 11:50PM | Duration 1h45 | Departure days Mon, Fri | Cheapest price $36 |
Live departures
Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA bus times
The table below shows live departures for Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA buses for today, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:20 PM Santa Ana Station, Santa Ana, CA | 1h30 | 9:50 PM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
![]() | 11:55 PM Santa Ana Station, Santa Ana, CA | 2h00 | 1:55 AM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
| Friday, November 7 | |||||
![]() | 2:10 PM Santa Ana Station, Santa Ana, CA | 1h35 | 3:45 PM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
![]() | 4:05 PM Santa Ana Station, Santa Ana, CA | 1h35 | 5:40 PM Santa Fe Depot, San Diego, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Journey information
Overview: Bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA
Buses from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA run on average 17 times per day, taking around 1h 56m. Cheap bus tickets for this journey start at $15 (€13) if you book in advance.
There are 16 buses per day. The earliest bus runs at 14:10, the last at 23:55. The fastest bus covers the 82 miles (132 km) distance in 1h 10m.
Distance 82 miles (132 km) |
Average bus duration 1h 56m |
Cheapest ticket price $15 (€13) |
Buses per day 17 |
Direct buses 16 |
Fastest bus 1h 10m |
First bus 14:10 |
Last bus 23:55 |
Bus providers: Greyhound, FlixBus, Infobus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CAYou can travel by bus between Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA with Greyhound, FlixBus, Infobus for as low as $15 (€13). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
Greyhound
FAQs: Bus from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA
Find answers to the most common questions about traveling from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Fe Depot, San Diego, CA, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
To find the cheapest bus tickets for your trip from Santa Ana Station, Santa Ana, CA to Santa Fe Depot, San Diego, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- Additional luggage can be purchased for a fee.
- Greyhound
- $15 per additional bag.
- Infobus
- 10€ per additional bag.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
- Infobus
- Small pets allowed in carriers
- Larger pets may require a separate ticket.


