- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Omio recommends booking the train as it is the most popular option from Santa Cruz, CA to San Francisco, CA among Omio's users. If you are prioritising price take the train with prices starting from zł110. For those with little time consider booking a train which can get you there in 2h 20m. The ticket price range depends on the travel mode: a train costs an average of zł110, and a bus costs an average of zł140.
Distance: 59 miles (95 km)
| Bus | Most popular Train | Driving |
|---|---|---|
zł143 Average price | zł132 Average price Cheapest | zł58 Average price (fuel + tolls) |
3h 13m Average total duration 2h 43m Onboard + 30m Additional time* | 2h 50m Average total duration Fastest 2h 20m Onboard + 30m Additional time* | 1h 22m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santa Cruz, CA to San Francisco, CA:
A train is zł10 less than a bus for this route with tickets for a bus from Santa Cruz, CA to San Francisco, CA costing on average zł143.
Other travel options to San Francisco, CA take longer:
Bus takes on average 2h 43m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 06:50AM | Arrival Time 11:30AM | Duration 4h40 | Departure days Sat | Cheapest price zł144 |
Operator Amtrak | Departure Time 01:45PM | Arrival Time 06:30PM | Duration 4h45 | Departure days Sun | Cheapest price zł150 |
Operator Amtrak | Departure Time 02:45PM | Arrival Time 07:30PM | Duration 4h45 | Departure days Sun | Cheapest price zł140 |
Operator Amtrak | Departure Time 04:25PM | Arrival Time 08:30PM | Duration 28h05 | Departure days Sat | Cheapest price zł144 |
Operator Amtrak | Departure Time 06:05PM | Arrival Time 09:10PM | Duration 27h05 | Departure days Sat | Cheapest price zł144 |
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Santa Cruz, CA to San Francisco, CA run on average 10 times per day, taking around 2h 43m. Cheap bus tickets for this journey start at zł140 but you can travel from only zł110 by train.
The earliest bus runs at 04:55, the last at 20:43. The fastest bus covers the 59 miles (95 km) distance in 4h 45m.
Distance 59 miles (95 km) |
Average bus duration 2h 43m |
Cheapest ticket price zł140 |
Buses per day 10 |
Fastest bus 4h 45m |
First bus 4:55 AM |
Last bus 8:43 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Best time to book 49 days |
Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Find answers to the most common questions about traveling from Santa Cruz, CA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

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