- Must visit
California Academy of Sciences
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Cheapest price on Sep 20
$38
Average ticket price on Sep 20
$39
Fastest journey on Sep 20
4 h 45 m
Average journey duration on Sep 20
4 h 45 m
Buses on Sep 20
2
Distance
95 km
The best way to find a cheap bus ticket from Santa Cruz, CA to San Francisco, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Cruz, CA to San Francisco, CA will cost around $39 if you buy it on the day, but the cheapest tickets can be found for only $38.
On Sun, Sep 20, we found 2 buses from Santa Cruz, CA to San Francisco, CA, including 2 direct services.
On Sun, Sep 20 the direct buses cover the 95 km distance in an average of 4 h 45 m but if you time it right, some buses will get you there in just 4 h 45 m .
On Sun, Sep 20 the slowest buses will take 4 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from Santa Cruz, CA to San Francisco, CA among Omio's users.
Distance: 59 miles (95 km)
| Bus | Most popular Train | Driving |
|---|---|---|
$16 Average price (fuel + tolls) | ||
1h 22m Average total duration (door-to-door) | ||
Direct Options | Direct Options | Direct Options |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 12:30AM | Arrival Time 04:30AM | Duration 28h00 | Departure days Sun | Cheapest price $37 |
Operator Amtrak | Departure Time 02:15AM | Arrival Time 05:10AM | Duration 26h55 | Departure days Sun | Cheapest price $37 |
Operator Amtrak | Departure Time 01:45PM | Arrival Time 06:30PM | Duration 4h45 | Departure days Sun | Cheapest price $40 |
Operator Amtrak | Departure Time 02:45PM | Arrival Time 07:30PM | Duration 4h45 | Departure days Sun | Cheapest price $38 |
Operator Amtrak | Departure Time 11:30PM | Arrival Time 03:30AM | Duration 28h00 | Departure days Sat | Cheapest price $38 |
The table below shows live departures for Santa Cruz, CA to San Francisco, CA buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:30 PM Santa Cruz, CA | 28h00 | 3:30 AM San Francisco, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a bus from Santa Cruz, CA to San Francisco, CA and enjoy the approximately 59 miles (95 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 04:55, the last at 20:43.
Distance 59 miles (95 km) |
First bus 4:55 AM |
Last bus 8:43 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Best time to book 49 days |
Discover the best of San Francisco, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Francisco, CA trip today.
Renowned science museum with rainforest dome, aquarium, and planetarium. Interactive exhibits make it a standout for all ages.
Major fine arts museum in Golden Gate Park with American art, textiles, and a panoramic tower. A classic cultural highlight.
Leading modern and contemporary art museum with landmark architecture and strong global collections. Essential for art-focused visitors.
Large urban park with gardens, lakes, museums, and trails. It is a must for relaxing, walking, and seeing several major attractions.
Steeply curving block lined with flowers and grand homes. This famous street offers classic photos and a quintessential San Francisco scene.
Popular waterfront promenade with bay views, piers, and ferries. Great for walking, people-watching, and connecting to nearby sights.
A crusty loaf with a tangy flavor shaped by the city’s historic wild yeast culture. It is one of San Francisco’s most iconic foods.
Fresh local Dungeness crab, often cracked and served simply or in cioppino. It is a Bay Area seasonal specialty tied to the fishing waterfront.
A tomato-based seafood stew created by Italian American fishermen in North Beach. It is a classic San Francisco dish built from the day’s catch.
Celebrated fine dining destination known for inventive tasting menus and polished service in an elegant, intimate setting.
Historic North Beach seafood house famous for cioppino, crab, and old-school San Francisco waterfront charm.
Legendary Mission taqueria known for large Mission-style burritos and a lively, no-frills local atmosphere.
Very high hotel, dining, and transport costs make San Francisco pricier than most US cities and many major tourist destinations.
Tip 18-20% at restaurants, 15-20% for taxis, and round up or tip $1 at cafes for good service.
Find answers to the most common questions about traveling from Santa Cruz, CA to San Francisco, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Francisco, CA, this guide helps you travel smarter and with confidence.

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