Travel Information
Compare bus, train, and flight for Santa Ana, CA to Santa Clara, CA
Omio recommends booking the flight as it is the most popular option from Santa Ana, CA to Santa Clara, CA among Omio's users. If you are prioritising price take the bus with prices starting from $110. For those with little time consider booking a flight which can get you there in 5h 18m. The ticket price range depends on the travel mode: a bus costs an average of $110, and a flight costs an average of $365.
Distance: 339 miles (546 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$110 Average price Cheapest | $365 Average price | $126 Average price | $77 Average price (fuel + tolls) |
15h 12m Average total duration 14h 42m Onboard + 30m Additional time* | 8h 18m Average total duration Fastest 5h 18m Onboard + 3h 0m Additional time* | 11h 16m Average total duration 10h 46m Onboard + 30m Additional time* | 6h 8m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santa Ana, CA to Santa Clara, CA:
A bus is $16 (€13) less than a train for this route with tickets for a train from Santa Ana, CA to Santa Clara, CA costing on average $126 (€102).
A bus is $255 (€206) less than a flight for this route with tickets for a flight from Santa Ana, CA to Santa Clara, CA costing on average $365 (€295).
Other travel options to Santa Clara, CA take longer:
Train takes on average 10h 46m.
Bus takes on average 14h 42m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Santa Ana, CA to Santa Clara, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 07:15AM | Arrival Time 09:57PM | Duration 14h42 | Departure days Fri | Cheapest price $110 |
Compare prices and tickets Santa Ana, CA to Santa Clara, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Santa Ana, CA to Santa Clara, CA
Buses from Santa Ana, CA to Santa Clara, CA run on average 3 times per day, taking around 14h 42m. Cheap bus tickets for this journey start at $110 (€89) if you book in advance.
The earliest bus runs at 00:55, the last at 23:45. The fastest bus covers the 339 miles (546 km) distance in 14h 42m.
Distance 339 miles (546 km) |
Average bus duration 14h 42m |
Cheapest ticket price $110 (€89) |
Buses per day 3 |
Fastest bus 14h 42m |
First bus 12:55 AM |
Last bus 11:45 PM |
Cheapest Month Jan |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Oct - Dec |
FAQs: Bus from Santa Ana, CA to Santa Clara, CA
Find answers to the most common questions about traveling from Santa Ana, CA to Santa Clara, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Clara, CA, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Santa Ana, CA to Santa Clara, CA
Most popular bus connections from Santa Ana, CA
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