Travel Information
Compare bus, train, and flight for San Diego, CA to Santa Clara, CA
Omio recommends booking the flight as it is the most popular option from San Diego, CA to Santa Clara, CA among Omio's users. If you are prioritising price take the train with prices starting from $119. For those with little time consider booking a flight which can get you there in 1h 39m. The ticket price range depends on the travel mode: a train costs an average of $119, and a flight costs an average of $153.
Distance: 420 miles (676 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$126 Average price | $174 Average price | $124 Average price Cheapest |
16h 4m Average total duration 15h 34m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 1h 39m Onboard + 3h 0m Additional time* | 14h 35m Average total duration 14h 5m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Diego, CA to Santa Clara, CA:
A train is $1 (€1) less than a bus for this route with tickets for a bus from San Diego, CA to Santa Clara, CA costing on average $126 (€103).
A train is $50 (€41) less than a flight for this route with tickets for a flight from San Diego, CA to Santa Clara, CA costing on average $174 (€143).
Other travel options to Santa Clara, CA take longer:
Train takes on average 14h 5m.
Bus takes on average 15h 34m.
San Diego, CA to Santa Clara, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 04:01AM | Arrival Time 05:32PM | Duration 13h31 | Departure days Mon | Cheapest price $175 |
Operator Amtrak | Departure Time 04:10AM | Arrival Time 05:32PM | Duration 13h22 | Departure days Mon | Cheapest price $175 |
Operator Amtrak | Departure Time 05:10AM | Arrival Time 09:57PM | Duration 16h47 | Departure days Thu, Fri | Cheapest price $121 |
Operator Amtrak | Departure Time 11:01AM | Arrival Time 12:57AM | Duration 13h56 | Departure days Fri, Sat | Cheapest price $133 |
Operator Amtrak | Departure Time 04:01PM | Arrival Time 06:24AM | Duration 14h23 | Departure days Mon | Cheapest price $175 |
Operator Amtrak | Departure Time 04:10PM | Arrival Time 06:24AM | Duration 14h14 | Departure days Mon | Cheapest price $175 |
Operator Amtrak | Departure Time 10:10PM | Arrival Time 02:57PM | Duration 16h47 | Departure days Mon | Cheapest price $162 |
Live departures
San Diego, CA to Santa Clara, CA bus times
The table below shows live departures for San Diego, CA to Santa Clara, CA buses for today, Monday, June 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
761 Pacific Surfliner · 4761 AMTRAK · 544 Capitol Corridor | 4:01 AM Santa Fe Depot, San Diego, CA | 13h31 | 5:32 PM Santa Clara Station, Santa Clara, CA | 2 transfers | |
761 Pacific Surfliner · 4761 AMTRAK · 544 Capitol Corridor | 4:10 AM Old Town Station, San Diego, CA | 13h22 | 5:32 PM Santa Clara Station, Santa Clara, CA | 2 transfers | |
785 Pacific Surfliner · 4785 AMTRAK · 524 Capitol Corridor | 4:01 PM Santa Fe Depot, San Diego, CA | 14h23 | 6:24 AM Santa Clara Station, Santa Clara, CA | 2 transfers | |
785 Pacific Surfliner · 4785 AMTRAK · 524 Capitol Corridor | 4:10 PM Old Town Station, San Diego, CA | 14h14 | 6:24 AM Santa Clara Station, Santa Clara, CA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to Santa Clara, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from San Diego, CA to Santa Clara, CA
Buses from San Diego, CA to Santa Clara, CA run on average 6 times per day, taking around 15h 34m. Cheap bus tickets for this journey start at $121 (€99) but you can travel from only $119 (€97) by train.
There are 1 buses per day. The earliest bus runs at 00:40, the last at 23:45. The fastest bus covers the 420 miles (676 km) distance in 13h 31m.
Distance 420 miles (676 km) |
Average bus duration 15h 34m |
Cheapest ticket price $121 (€99) |
Buses per day 6 |
Direct buses 1 |
Fastest bus 13h 31m |
First bus 12:40 AM |
Last bus 11:45 PM |
Cheapest Month Jun |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Oct - Dec |
Best time to book 14 days |
FAQs: Bus from San Diego, CA to Santa Clara, CA
Find answers to the most common questions about traveling from San Diego, CA to Santa Clara, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Clara, CA, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from San Diego, CA to Santa Clara, CA
Most San Diego, CA to Santa Clara, CA buses use the San Diego, Congress Street (Old Town Park) to San José, Cahill Street (Diridon Station) station pair. Use this guide to compare San Diego, CA and Santa Clara, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
Getting to San Diego from San Diego city centre
More options for your journey from San Diego, CA to Santa Clara, CA
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