San Diego, CA to Santa Clara, CA bus

Sun, Aug 23
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Rede Expressos
Flibco
2,000+ travel companies
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Travel Information

Compare bus, train, and flight for San Diego, CA to Santa Clara, CA

Omio recommends booking the flight as it is the most popular option from San Diego, CA to Santa Clara, CA among Omio's users. If you are prioritising price take the train with prices starting from €96. For those with little time consider booking a flight which can get you there in 1h 39m. The ticket price range depends on the travel mode: a train costs an average of €96, and a flight costs an average of €129.

Distance: 420 miles (676 km)

Compare bus with

Bus
Most popular
Flight
Train

€116

Average price

€214

Average price

€105

Average price

Cheapest

16h 34m

Average total duration

16h 4m

Onboard

+

30m

Additional time*

4h 39m

Average total duration

Fastest

1h 39m

Onboard

+

3h 0m

Additional time*

14h 35m

Average total duration

14h 5m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

The cheapest way to travel from San Diego, CA to Santa Clara, CA is a train with an average price of €105.

This is compared to other travel options from San Diego, CA to Santa Clara, CA:

A train is €11 less than a bus for this route with tickets for a bus from San Diego, CA to Santa Clara, CA costing on average €116.

A train is €109 less than a flight for this route with tickets for a flight from San Diego, CA to Santa Clara, CA costing on average €214.

The fastest way to travel from San Diego, CA to Santa Clara, CA is by flight with an average journey time of 1h 39m.

Other travel options to Santa Clara, CA take longer:

Train takes on average 14h 5m.

Bus takes on average 16h 4m.

It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and Santa Clara, CA including taking a bus, train, and flight.
We recommend using the flight as it is the most popular way to get from San Diego, CA to Santa Clara, CA among Omio's users.

San Diego, CA to Santa Clara, CA Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Amtrak
Departure Time
05:10AM
Arrival Time
09:57PM
Duration
16h47
Departure days
Thu, Fri
Cheapest price
99
Operator
Amtrak
Departure Time
11:01AM
Arrival Time
12:57AM
Duration
13h56
Departure days
Fri, Sat
Cheapest price
109

Live departures

San Diego, CA to Santa Clara, CA bus times

The table below shows live departures for San Diego, CA to Santa Clara, CA buses for today, Saturday, August 22. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Amtrak11:01 AM San Diego, CA
13h56
12:57 AM Santa Clara, CA0 transfersDirect

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets San Diego, CA to Santa Clara, CA by bus, train, or flight

Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Aug 23
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Journey information

Overview: Bus from San Diego, CA to Santa Clara, CA

USAUSA
USAUSA
Icon of bus

Buses from San Diego, CA to Santa Clara, CA run on average 6 times per day, taking around 16h 4m. Cheap bus tickets for this journey start at €98 but you can travel from only €96 by train.

The earliest bus runs at 00:40, the last at 23:45. The fastest bus covers the 420 miles (676 km) distance in 13h 56m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €96
Distance
420 miles (676 km)
Average bus duration
16h 4m
Cheapest ticket price
€98
Buses per day
6
Fastest bus
13h 56m
First bus
12:40 AM
Last bus
11:45 PM
Cheapest Month
Dec
Cheapest Day
Fri
High Season
Apr - Jun
Low Season
Jul - Sep
Best time to book
14 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €96

FAQs: Bus from San Diego, CA to Santa Clara, CA

Find answers to the most common questions about traveling from San Diego, CA to Santa Clara, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Clara, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from San Diego, CA to Santa Clara, CA can start from as little as €98 when you book in advance. The average bus ticket price for San Diego, CA to Santa Clara, CA is €116 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from San Diego, CA to Santa Clara, CA is 13h 56m to travel the 420 miles (676 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from San Diego, CA to Santa Clara, CA leaves at 12:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from San Diego, CA to Santa Clara, CA leaves at 11:45 PM.
When departing from San Diego, CA , you have various bus station options to start your journey from including San Diego, Congress Street (Old Town Park), CA, San Diego, San Ysidro Transit Center, La Jolla, UCSD Health La Jolla Station, CA, San Diego, West Harbor Drive (The Headquarters at Seaport District), CA, San Diego, CA . When arriving in Santa Clara, CA , you can end your journey in bus stations like San José, Cahill Street (Diridon Station), San Jose, CA, Redwood City Station, CA .Passengers board the bus most frequently from San Diego, Congress Street (Old Town Park), CA, which is located around 3 miles (5 km) away from the city centre, and they get off the bus at San José, Cahill Street (Diridon Station), located 1 away from the city centre.
A trip to Santa Clara, CA from San Diego, CA is worth doing but not as a day trip with a journey time of 13h 56m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from San Diego, CA to Santa Clara, CA is December.
It's helpful to compare your options as there are 3 ways to travel between San Diego, CA and Santa Clara, CA including taking a bus, train, and flight.
No, there are no bathrooms on board the bus from San Diego, CA to Santa Clara, CA.
No, the bus from San Diego, CA to Santa Clara, CA has no accessibility options.
No, bikes are not allowed on board the bus from San Diego, CA to Santa Clara, CA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from San Diego, CA to Santa Clara, CA.
No, luggage for the bus from San Diego, CA to Santa Clara, CA needs to be booked in addition.
No, there are no additional luggage options for the bus from San Diego, CA to Santa Clara, CA.
Unfortunately, pets are not allowed on the bus from San Diego, CA to Santa Clara, CA.
No, there are no USB plugs on board the bus from San Diego, CA to Santa Clara, CA.
No, there is no WiFi on board the bus from San Diego, CA to Santa Clara, CA.
Since neither San Diego, CA nor Santa Clara, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from San Diego, CA to Santa Clara, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Santa Clara, CA, travelers should be cautious of pickpocketing in crowded areas and be aware of occasional vehicle break-ins, especially in parking lots near popular attractions. Common scams include overcharging by unauthorized taxi or ride-share drivers and fake ticket sellers near event venues. It's advisable to use official transportation services and remain vigilant in busy public spaces.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from San Diego, CA to Santa Clara, CA

Most San Diego, CA to Santa Clara, CA buses use the San Diego, Congress Street (Old Town Park) to San José, Cahill Street (Diridon Station) station pair. Use this guide to compare San Diego, CA and Santa Clara, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in San Diego
Arrival bus stations in Santa Clara

Which San Diego, CA station do buses to Santa Clara, CA leave from?

Buses from San Diego, CA to Santa Clara, CA leave from San Diego, Congress Street (Old Town Park). The station is 3 miles (6 km) from San Diego, CA city centre at Congress St, San Diego, CA 92110, USA.
San Diego, Congress Street (Old Town Park)Congress St, San Diego, CA 92110, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre

San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:

BusFlixBus 2017 · 20m · €1
83 · 26m · €5
TramGreen, Blue, Event · 16m · every ~18 min
Blue · 21m · every ~9 min

San Diego, Congress Street (Old Town Park) bus station facilities and services

San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several dining options nearby.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).

Tickets and information

Ticket office support is available at San Diego, Congress Street (Old Town Park).

Parking, taxis and toilets

Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.

San Diego, San Ysidro Transit CenterSan Ysidro Station, San Diego, CA 92173, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, San Ysidro Transit Center from San Diego city centre

San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:

BusFlixBus 2017 · 25m · €2
910 · 41m · €5
TramBlue · 41m · €14 · every ~14 min
Blue · 43m · €14 · every ~14 min

San Diego, San Ysidro Transit Center bus station facilities and services

San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several fast food eateries located nearby.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.

Tickets and information

Ticket office support is available at San Diego, San Ysidro Transit Center.

Parking, taxis and toilets

Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.

San Diego, West Harbor Drive (The Headquarters at Seaport District)W Harbor Dr, San Diego, CA, USAWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to San Diego, West Harbor Drive (The Headquarters at Seaport District) from San Diego city centre

San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:

TRUE

San Diego, West Harbor Drive (The Headquarters at Seaport District) bus station facilities and services

San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Several dining options are in the area.

Wi-Fi and ATMs

Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).

Tickets and information

Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).

Parking, taxis and toilets

Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.

More options for your journey from San Diego, CA to Santa Clara, CA

Here are some other resources that might have the information you need

Most popular buses to and from Santa Clara, CA and San Diego, CA

Most popular bus connections to Santa Clara, CA

HomeBusesBuses in USABus tickets to Santa Clara, CASan Diego, CA to Santa Clara, CA bus

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