The cheapest and fastest buses from San Diego, CA to Santa Clara, CA
Cheapest price
$120
Average price
$120
Fastest journey
16 h 47 m
Average duration
16 h 47 m
Buses per day
1
Distance
676 km
The best way to find a cheap bus ticket from San Diego, CA to Santa Clara, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from San Diego, CA to Santa Clara, CA will cost around $120 if you buy it on the day, but the cheapest tickets can be found for only $120.
Of the 1 buses that leave San Diego, CA for Santa Clara, CA on Tue, Mar 24, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Mar 24 the direct buses cover the 676 km distance in an average of 16 h 47 m but if you time it right, some buses will get you there in just 16 h 47 m .
On Tue, Mar 24 the slowest buses will take 16 h 47 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for San Diego, CA to Santa Clara, CA
Omio recommends booking the flight as it is the most popular option from San Diego, CA to Santa Clara, CA among Omio's users. If you are prioritising price take the bus with prices starting from $101. For those with little time consider booking a flight which can get you there in 1h 44m. The ticket price range depends on the travel mode: a bus costs an average of $101, and a flight costs an average of $101.
Distance: 420 miles (676 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$118 Average price Cheapest | $176 Average price | $137 Average price |
15h 16m Average total duration 14h 46m Onboard + 30m Additional time* | 4h 44m Average total duration Fastest 1h 44m Onboard + 3h 0m Additional time* | 14h 46m Average total duration 14h 16m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets San Diego, CA to Santa Clara, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Mar 29
Journey information
Overview: Bus from San Diego, CA to Santa Clara, CA
Buses from San Diego, CA to Santa Clara, CA run on average 7 times per day, taking around 14h 46m. Cheap bus tickets for this journey start at $101 (€82) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:40, the last at 23:45. The fastest bus covers the 420 miles (676 km) distance in 13h 10m.
Distance 420 miles (676 km) |
Average bus duration 14h 46m |
Cheapest ticket price $101 (€82) |
Buses per day 7 |
Direct buses 1 |
Fastest bus 13h 10m |
First bus 00:40 |
Last bus 23:45 |
FAQs: Bus from San Diego, CA to Santa Clara, CA
Find answers to the most common questions about traveling from San Diego, CA to Santa Clara, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Clara, CA, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from San Diego, CA to Santa Clara, CA
More options for your journey from San Diego, CA to Santa Clara, CA
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