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Journey information
Overview: Bus from San Diego, CA to Santa Clara, CA
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 420 miles (676 km) |
Buses per day 8 |
Direct buses 2 |
First bus 00:40 |
Last bus 23:45 |
Key Takeaways
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
FAQs: Bus from San Diego, CA to Santa Clara, CA
Find answers to the most common questions about traveling from San Diego, CA to Santa Clara, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Clara, CA, this guide helps you travel smarter and with confidence.

Cheap bus tickets from San Diego, CA to Santa Clara, CA can start from as little as $56 (€46) when you book in advance. The average bus ticket price for San Diego, CA to Santa Clara, CA is $65 (€53); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The bus time from San Diego, CA to Santa Clara, CA is on average 11 h 25 min for the 419 mile (675 km) long journey, but the time it takes to go from San Diego, CA to Santa Clara, CA by bus can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from San Diego, CA to Santa Clara, CA leaves at 12: 15AM. Plan your trip with the Journey Planner from Omio.
The last bus from San Diego, CA to Santa Clara, CA leaves at 11: 45PM.
There are 11 buses a day from San Diego, CA to Santa Clara, CA which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from San Diego, CA to Santa Clara, CA, you can count on FlixBus for the best way to get you to Santa Clara, CA. You can also check all possible bus companies who offer a service from San Diego, CA to Santa Clara, CA and compare the amenities they offer before buying a bus ticket.
The cheapest month to travel from San Diego, CA to Santa Clara, CA by bus is September.
Yes, you can take a bus to Santa Clara, CA from San Diego, CA.
Yes, the following accessibility options are available when taking the bus from San Diego, CA to Santa Clara, CA:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from San Diego, CA to Santa Clara, CA for bus company FlixBus.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from San Diego, CA to Santa Clara, CA depends on the bus company:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from San Diego, CA to Santa Clara, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from San Diego, CA to Santa Clara, CA.
Yes, the following luggage options are included when booking a bus ticket from San Diego, CA to Santa Clara, CA:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from San Diego, CA to Santa Clara, CA:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from San Diego, CA to Santa Clara, CA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
You can reserve your seat on the bus from San Diego, CA to Santa Clara, CA with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from San Diego, CA to Santa Clara, CA with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from San Diego, CA to Santa Clara, CA with the following bus company: FlixBus.
popular bus stations
Popular bus stations from San Diego, CA to Santa Clara, CA
San Diego
Santa Clara
San Diego, San Ysidro Transit Center
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San Diego, Congress Street (Old Town Park)
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San Diego, West Harbor Drive (The Headquarters at Seaport District)
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San Diego
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More options for your journey from San Diego, CA to Santa Clara, CA
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