Travel Information
Compare bus, train, and flight for San Diego, CA to Santa Clara, CA
Omio recommends booking the flight as it is the most popular option from San Diego, CA to Santa Clara, CA among Omio's users. If you are prioritising price take the train with prices starting from €96. For those with little time consider booking a flight which can get you there in 1h 39m. The ticket price range depends on the travel mode: a train costs an average of €96, and a flight costs an average of €129.
Distance: 420 miles (676 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€116 Average price | €214 Average price | €105 Average price Cheapest |
16h 34m Average total duration 16h 4m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 1h 39m Onboard + 3h 0m Additional time* | 14h 35m Average total duration 14h 5m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from San Diego, CA to Santa Clara, CA:
A train is €11 less than a bus for this route with tickets for a bus from San Diego, CA to Santa Clara, CA costing on average €116.
A train is €109 less than a flight for this route with tickets for a flight from San Diego, CA to Santa Clara, CA costing on average €214.
Other travel options to Santa Clara, CA take longer:
Train takes on average 14h 5m.
Bus takes on average 16h 4m.
San Diego, CA to Santa Clara, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Amtrak | Departure Time 05:10AM | Arrival Time 09:57PM | Duration 16h47 | Departure days Thu, Fri | Cheapest price €99 |
Operator Amtrak | Departure Time 11:01AM | Arrival Time 12:57AM | Duration 13h56 | Departure days Fri, Sat | Cheapest price €109 |
Live departures
San Diego, CA to Santa Clara, CA bus times
The table below shows live departures for San Diego, CA to Santa Clara, CA buses for today, Saturday, August 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:01 AM San Diego, CA | 13h56 | 12:57 AM Santa Clara, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets San Diego, CA to Santa Clara, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from San Diego, CA to Santa Clara, CA
Buses from San Diego, CA to Santa Clara, CA run on average 6 times per day, taking around 16h 4m. Cheap bus tickets for this journey start at €98 but you can travel from only €96 by train.
The earliest bus runs at 00:40, the last at 23:45. The fastest bus covers the 420 miles (676 km) distance in 13h 56m.
Distance 420 miles (676 km) |
Average bus duration 16h 4m |
Cheapest ticket price €98 |
Buses per day 6 |
Fastest bus 13h 56m |
First bus 12:40 AM |
Last bus 11:45 PM |
Cheapest Month Dec |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Jul - Sep |
Best time to book 14 days |
FAQs: Bus from San Diego, CA to Santa Clara, CA
Find answers to the most common questions about traveling from San Diego, CA to Santa Clara, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santa Clara, CA, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from San Diego, CA to Santa Clara, CA
Most San Diego, CA to Santa Clara, CA buses use the San Diego, Congress Street (Old Town Park) to San José, Cahill Street (Diridon Station) station pair. Use this guide to compare San Diego, CA and Santa Clara, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which San Diego, CA station do buses to Santa Clara, CA leave from?
Getting to San Diego, Congress Street (Old Town Park) from San Diego city centre
San Diego, Congress Street (Old Town Park) is 5 km from San Diego city centre. Public transport options include:
San Diego, Congress Street (Old Town Park) bus station facilities and services
San Diego, Congress Street (Old Town Park) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, Congress Street (Old Town Park). ATMs are available at San Diego, Congress Street (Old Town Park).
Tickets and information
Ticket office support is available at San Diego, Congress Street (Old Town Park).
Parking, taxis and toilets
Available at San Diego, Congress Street (Old Town Park): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, Congress Street (Old Town Park): Wheelchair accessible routes available.
Getting to San Diego, San Ysidro Transit Center from San Diego city centre
San Diego, San Ysidro Transit Center is 22 km from San Diego city centre. Public transport options include:
San Diego, San Ysidro Transit Center bus station facilities and services
San Diego, San Ysidro Transit Center has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several fast food eateries located nearby.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, San Ysidro Transit Center. ATMs are available near the entrance.
Tickets and information
Ticket office support is available at San Diego, San Ysidro Transit Center.
Parking, taxis and toilets
Available at San Diego, San Ysidro Transit Center: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, San Ysidro Transit Center: Wheelchair accessible with ramps.
Getting to San Diego, West Harbor Drive (The Headquarters at Seaport District) from San Diego city centre
San Diego, West Harbor Drive (The Headquarters at Seaport District) is 1 km from San Diego city centre. Public transport options include:
San Diego, West Harbor Drive (The Headquarters at Seaport District) bus station facilities and services
San Diego, West Harbor Drive (The Headquarters at Seaport District) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several dining options are in the area.
Wi-Fi and ATMs
Wi-Fi is available at San Diego, West Harbor Drive (The Headquarters at Seaport District). ATMs are available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Tickets and information
Ticket office support is available at San Diego, West Harbor Drive (The Headquarters at Seaport District).
Parking, taxis and toilets
Available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at San Diego, West Harbor Drive (The Headquarters at Seaport District): Accessible for persons with disabilities.
More options for your journey from San Diego, CA to Santa Clara, CA
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