- Must visit
Denver Art Museum
One of the largest art museums in the West, known for Indigenous art, global collections, and striking architecture.
Flights from Santa Ana, CA to Denver, CO depart on average 86 times per day, taking around 2h 25m. Cheap flight tickets for this journey start at $180 but you can travel from only $144 by bus.
There are 7 flights per day. The earliest flight runs at 05:00, the last at 22:52. The fastest flight covers the 823 miles (1325 km) distance in 2h 19m. May is the cheapest month to fly.
Distance 823 miles (1325 km) |
Average flight duration 2h 25m |
Cheapest ticket price $180 |
Flights per day 86 |
Direct flights 7 |
Fastest flight 2h 19m |
First flight 5:00 AM |
Last flight 10:52 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Cheapest price
$180
Average price
$180
Fastest journey
5 h 14 m
Average duration
5 h 14 m
Flights per day
1
Distance
1325 km
The best way to find a cheap flight ticket from Santa Ana, CA to Denver, CO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Ana, CA to Denver, CO will cost around $180 if you buy it on the day, but the cheapest tickets can be found for only $180.
Of the 1 flights that leave Santa Ana, CA for Denver, CO onFri, Aug 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Aug 07 the direct flights cover the 1325 km distance in an average of 5 h 14 m but if you time it right, some flights will get you there in just 5 h 14 m .
On Fri, Aug 07 the longest flights will take 5 h 14 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the flight as it is the most popular option from Santa Ana, CA to Denver, CO among Omio's users. If you are prioritising price take the bus with prices starting from $144. For those with little time consider booking a flight which can get you there in 2h 25m. The ticket price range depends on the travel mode: a bus costs an average of $144, and a train costs an average of $274.
Distance: 823 miles (1325 km)
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
$275 Average price | $388 Average price | $195 Average price Cheapest | $206 Average price (fuel + tolls) |
5h 25m Average total duration Fastest 2h 25m Onboard + 3h 0m Additional time* | 47h 53m Average total duration 47h 23m Onboard + 30m Additional time* | 29h 35m Average total duration 29h 5m Onboard + 30m Additional time* | 14h 52m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santa Ana, CA to Denver, CO:
A bus is $80 less than a flight for this route with tickets for a flight from Santa Ana, CA to Denver, CO costing on average $275.
A bus is $193 less than a train for this route with tickets for a train from Santa Ana, CA to Denver, CO costing on average $388.
Other travel options to Denver, CO take longer:
Bus takes on average 29h 5m.
Train takes on average 47h 23m.
The table below shows live departures for Santa Ana, CA to Denver, CO flights for tomorrow, Thursday, August 6. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:25 AM Santa Ana, CA | 5h14 | 6:39 AM Denver, CO | 0 transfersDirect | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Denver, CO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Denver, CO trip today.
One of the largest art museums in the West, known for Indigenous art, global collections, and striking architecture.
A major natural history museum with dinosaur fossils, space exhibits, wildlife dioramas, and rooftop city views.
This museum explores Colorado and Western heritage through Native history, artifacts, and regional storytelling.
Denver's landmark downtown park and civic heart, framed by museums, government buildings, festivals, and open lawns.
A scenic urban lake and park with skyline and mountain views, trails, boating, and one of Denver's best sunsets.
A lively pedestrian mall lined with shops, public art, and free shuttle service through the center of downtown Denver.
Denver omelet with ham, bell peppers, onions, and cheese. It is strongly associated with the city and remains a classic local breakfast order.
Green chile is a beloved Front Range staple, served as a pork-rich stew or smothered over burritos, fries, and breakfast plates across Denver.
A juicy burger topped with roasted green chiles and cheese. It reflects Colorado's chile-loving comfort food culture and is common in Denver pubs.
Acclaimed fine dining restaurant focused on wood-fired New American cuisine, seasonal Colorado ingredients, and polished service in an elegant room.
Popular modern Mexican spot celebrated for green chile, tacos, and strong margaritas. Casual atmosphere with a long local following.
Beloved neighborhood eatery serving creative breakfasts and brunch. A reliable place to try a Denver omelet in a relaxed, local setting.
Moderate for a major US city: hotels and dining are mid-to-high, while transit is reasonable. Costs are usually lower than New York or San Francisco.
Tip 18-20% at restaurants, $1-$2 per drink at bars, and 10-15% for taxis. Cafes often have tip screens; rounding up or $1 is common.
Find answers to the most common questions about traveling from Santa Ana, CA to Denver, CO by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Denver, CO, this guide helps you travel smarter and with confidence.

Most Santa Ana, CA to Denver, CO flights use the John Wayne Airport to Denver International Airport airport pair. Use this guide to compare Santa Ana, CA and Denver, CO airports on this route, check city-centre transport, alongside checking practicalities like airport facilities and services.
John Wayne Airport is 3 km from Santa Ana city centre. Public transport options include:
John Wayne Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Located in terminals; options include fast food and sit-down restaurants like McDold's and Ruby's Diner
Free Wi-Fi available throughout the airport. ATMs are located in all terminals.
Lost and found is available at the station.
Available at John Wayne Airport: Parking, Taxis, WC.
Available at John Wayne Airport: Car Rental.
Accessibility facilities are available at John Wayne Airport: Elevators, ramps.
Nearby hotels include Hotels within walking distance, Hilton Irvine/Orange County Airport..
Denver International Airport is 18 km from Denver city centre. Public transport options include:
Denver International Airport has practical services for this route, including Wifi, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, and Car Rental.
Food options include: Various restaurants in Jeppesen terminal and concourses, including American and intertiol cuisine.
Free Wi-Fi available throughout the airport. ATMs are located throughout the terminal and concourses.
Lost and found is available at the station.
Available at Denver International Airport: Parking, Taxis, WC.
Available at Denver International Airport: Car Rental.
Accessibility facilities are available at Denver International Airport: Elevators, ramps.
Nearby hotels include Westin Hotel connected to the terminal..
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