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Centro Botín
Leading modern and contemporary art center by Renzo Piano, renowned for exhibitions, architecture, and exceptional bay views.
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The cheapest and fastest buses from Rome to Santander
Showing times, prices and bookable tickets for Oct 01
Cheapest price on Oct 01
$127
Average ticket price on Oct 01
$131
Fastest journey on Oct 01
1 d 13 h 45 m
Average journey duration on Oct 01
1 d 14 h 50 m
Buses on Oct 01
2
Distance
1341 km
Cheap tickets
The best way to find a cheap bus ticket from Rome to Santander is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Santander will cost around $131 if you buy it on the day, but the cheapest tickets can be found for only $127.
Fast buses
It's difficult to get from Rome to Santander without transferring at least 2 times.
FlixBus · FlixBus · FlixBus5:25 PM39h55Roma, Autostazione (Metro Anagnina)9:20 AMSantander, Estación de Autobuses$1271One-way2 transfers- FlixBus · FlixBus · FlixBus7:35 PM37h45Roma, Autostazione Tiburtina9:20 AMSantander, Estación de Autobuses$1351One-way2 transfers
- FlixBus · FlixBus · FlixBus7:35 PM37h45Roma, Autostazione Tiburtina9:20 AMSantander, Estación de Autobuses$1351One-way2 transfers
- FlixBus · FlixBus · FlixBus5:25 PM39h55Roma, Autostazione (Metro Anagnina)9:20 AMSantander, Estación de Autobuses$1271One-way2 transfers
Rome to Santander Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 10:40AM | Arrival Time 09:20AM | Duration 46h40 | Departure days Tue | Cheapest price $114 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 09:20AM | Duration 44h15 | Departure days Mon, Tue, Wed | Cheapest price $102 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 09:20AM | Duration 39h55 | Departure days Thu, Fri, Sat, Sun | Cheapest price $127 |
Operator FlixBus | Departure Time 07:35PM | Arrival Time 09:20AM | Duration 37h45 | Departure days Thu, Fri | Cheapest price $135 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 09:20AM | Duration 37h20 | Departure days Sat, Sun | Cheapest price $129 |
Live departures
Rome to Santander bus times
The table below shows live departures for Rome to Santander buses for tomorrow, Thursday, October 1. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 39h55 | 9:20 AM Santander, Estación de Autobuses | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 7:35 PM Roma, Autostazione Tiburtina | 37h45 | 9:20 AM Santander, Estación de Autobuses | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Santander by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Rome to Santander buses with Omio?
FlixBus operates all buses services from Rome to Santander.
Omio is an official ticket reseller for all your travel options from Rome to Santander.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Rome to Santander.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Rome to Santander.
Journey information
Overview: Bus from Rome to Santander
Italy
Spain
Buses from Rome to Santander run on average 2 times per day, taking around 30h 39m. Cheap bus tickets for this journey start at $94 (€77) but you can travel from only $39 (€32) by flight.
The earliest bus runs at 09:25, the last at 22:45. The fastest bus covers the 833 miles (1341 km) distance in 28h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $39 (€32)
Distance 833 miles (1341 km) |
Average bus duration 30h 39m |
Cheapest ticket price $94 (€77) |
Buses per day 2 |
Fastest bus 28h 10m |
First bus 9:25 AM |
Last bus 10:45 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Fri |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $39 (€32)
Bus providers: FlixBus from Rome to SantanderYou can travel by bus between Rome to Santander with FlixBus for as low as $39 (€32). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
28h 10m
Cheapest FlixBus Price
$94 (€77)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Santander
Things to do in Santander
Discover the best of Santander — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Santander trip today.
- Must visit
Museo Marítimo del Cantábrico
Excellent maritime museum covering Cantabrian seafaring, ecology, fishing, and naval history with aquariums and family-friendly displays.
- Recommended
MAS | Museo de Arte Moderno y Contemporáneo de Santander y Cantabria
Art museum focused on Cantabrian and Spanish painting, offering a compact but rewarding overview in a central historic setting.
- Must visit
Península de La Magdalena
Iconic peninsula park with palace grounds, beaches, mini-zoo area, and scenic walking routes. One of Santander’s essential outings.
- Must visit
Paseo de Pereda
Elegant seafront promenade linking gardens, monuments, and bay views. Ideal for a first walk through central Santander.
- Must visit
Cabo Mayor
Dramatic headland viewpoint with cliffs, lighthouse scenery, and walking trails. A favorite for sunsets and Atlantic panoramas.
- Gluten-free
Anchoas De Cantabria
Cantabrian anchovies cured in salt or olive oil. Santander is famous for high-quality bocarte landed on this coast and served as a prized tapa.
Merluza En Salsa Verde
Fresh hake with green sauce, usually with garlic, parsley, fish stock, peas and clams. A classic northern coastal dish tied to local fishing traditions.
- Gluten-free
Cocido Montañés
Mountain stew from Cantabria with white beans, collard greens and pork products. Hearty inland cooking that is iconic across the region.
Cenador De Amos
Refined Michelin-starred dining focused on seasonal Cantabrian products. Elegant setting and creative tasting menus with strong local identity.
El Serbal
Well-known dining room specializing in grilled fish and Cantabrian seafood. Smart but relaxed atmosphere with a strong local reputation.
Casa Lita
Established seafood restaurant known for fresh fish, shellfish and classic Santander cooking. Traditional atmosphere near the seafront.
Euro (€)
Moderate for Spain. Hotels and dining are usually cheaper than Madrid or Barcelona, while local transit and casual meals stay fairly affordable for tourists.
Average meal costs
- Budget
- €8-12 for fast food or a simple lunch.
- Mid-range
- €18-30 per person for a restaurant meal.
- Fine dining
- €50+ per person for upscale dining.
- Coffee
- €1.50-3 for coffee or cappuccino.
Tipping culture
Tipping is modest. Round up or leave 5-10% in restaurants for good service, small change in cafes, and round up taxi fares.
FAQs: Bus from Rome to Santander
Find answers to the most common questions about traveling from Rome to Santander by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santander, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Rome to Santander can start from as little as $94 (€77) when you book in advance. The average bus ticket price for Rome to Santander is $193 (€159) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Rome to Santander is 28h 10m to travel the 833 miles (1341 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Rome to Santander leaves at 9:25 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rome to Santander leaves at 10:45 PM.
There are 2 buses a day from Rome to Santander which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Rome to Santander, you can count on FlixBus for the best way to get you to Santander. You can also check all possible bus companies who offer a service between Rome and Santander and compare the amenities they offer before buying a bus ticket.
When departing from Rome , you have various bus station options to start your journey from including Roma, Autostazione (Metro Anagnina), Roma, Autostazione Tiburtina . When arriving in Santander , you can end your journey in bus stations like Santander, Estación de Autobuses .Passengers board the bus most frequently from Roma, Autostazione (Metro Anagnina), which is located around away from the city centre, and they get off the bus at Santander, Estación de Autobuses, located 0 away from the city centre.
It's helpful to compare your options as there are 2 ways to travel between Rome and Santander including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Rome to Santander:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Rome to Santander for bus company FlixBus.
Whether you can cancel your bus ticket from Rome to Santander depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Rome to Santander.
Yes, the following luggage options are included when booking a bus ticket from Rome to Santander:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Rome to Santander:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Rome to Santander. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Rome to Santander with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Rome to Santander with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Rome to Santander with the following bus company: FlixBus.
Spain uses the euro (€) as its currency. Travelers can use both cash and cards, but cards are widely accepted in cities and tourist areas, while cash may be preferred for small purchases, markets, and rural locations.
In Santander, travelers should be cautious of pickpocketing, especially in crowded areas such as public transport and popular tourist spots. Scams involving overcharging or unofficial taxi services can occur, so it's recommended to use licensed taxis and agree on fares beforehand. Additionally, travelers should be wary of distraction techniques used by thieves in busy markets or near attractions. Staying alert and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Rome to Santander
Most Rome to Santander buses use the Roma, Autostazione (Metro Anagnina) to Santander, Estación de Autobuses station pair. Use this guide to compare Rome and Santander bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Rome
Arrival bus stations in Santander
Roma, Autostazione (Metro Anagnina)Rome Anagnina, Via Tuscolana, 173
City-centre transport
Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre
BusRome Fiumicino, Scario · 31m · $1
nMA · 38m · $2 · every ~4 min
SubwayMea · 24m · $2 · every ~29 min
Shuttle31m · $12
Roma, Autostazione TiburtinaLargo Guido Mazzoni, snc, 00162 Roma RM, Italy
City-centre transport
Getting to Roma, Autostazione Tiburtina from Rome city centre
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Bus490, 495 · 16m · $2 · every ~22 min
SubwayMeb · 7m · $2 · every ~15 min
Roma, Autostazione Tiburtina bus station facilities and services
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafes and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Roma, Autostazione Tiburtina.
Parking, taxis and toilets
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Santander, Estación de AutobusesSantander Bus Station, Calle Navas de Tolosa 2, 39002
More options for your journey from Rome to Santander
Here are some other resources that might have the information you need
Most popular buses to and from Santander and Rome
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