- Must visit
Centro Botín
Leading modern and contemporary art center by Renzo Piano, renowned for exhibitions, architecture, and exceptional bay views.
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The cheapest and fastest buses from Rome to Santander
Showing times and prices for Aug 17
Cheapest price
$169
Average price
$187
Fastest journey
1 d 11 h 25 m
Average duration
1 d 13 h 42 m
Buses per day
3
Distance
1341 km
Cheap tickets
The best way to find a cheap bus ticket from Rome to Santander is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Santander will cost around $187 if you buy it on the day, but the cheapest tickets can be found for only $169.
Fast buses
It's difficult to get from Rome to Santander without transferring at least 2 times.
FlixBus · FlixBus · FlixBus5:25 PM39h55Roma, Autostazione (Metro Anagnina)9:20 AMSantander, Estación de Autobuses$1691One-way2 transfers- FlixBus · FlixBus · FlixBus · FlixBus9:55 PM35h25Roma, Autostazione Tiburtina9:20 AMSantander, Estación de Autobuses$1831One-way3 transfers
- FlixBus · FlixBus · FlixBus7:35 PM37h45Roma, Autostazione Tiburtina9:20 AMSantander, Estación de Autobuses$2081One-way2 transfers
- FlixBus · FlixBus · FlixBus · FlixBus9:55 PM35h25Roma, Autostazione Tiburtina9:20 AMSantander, Estación de Autobuses$1831One-way3 transfers
- FlixBus · FlixBus · FlixBus7:35 PM37h45Roma, Autostazione Tiburtina9:20 AMSantander, Estación de Autobuses$2081One-way2 transfers
- FlixBus · FlixBus · FlixBus5:25 PM39h55Roma, Autostazione (Metro Anagnina)9:20 AMSantander, Estación de Autobuses$1691One-way2 transfers
Travel Information
Compare bus and flight for Rome to Santander
Omio recommends booking the flight as it is the most popular option from Rome to Santander among Omio's users. If you are prioritising price take the bus with prices starting from $105. For those with little time consider booking a flight which can get you there in 3h 3m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.3 - 3.4kg. The ticket price range depends on the travel mode: a bus costs an average of $105, and a flight costs an average of $72.
Distance: 833 miles (1341 km)
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
$171 Average price Cheapest | $265 Average price | $562 Average price (fuel + tolls) |
38h 35m Average total duration 38h 5m Onboard + 30m Additional time* | 6h 3m Average total duration Fastest 3h 3m Onboard + 3h 0m Additional time* | 18h 0m Average total duration (door-to-door) |
1.3 - 3.4kg CO2 emissions Lowest | 4.0 - 8.0kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Rome to Santander is a bus with an average price of $171.
This is compared to other travel options from Rome to Santander:
A bus is $94 less than a flight for this route with tickets for a flight from Rome to Santander costing on average $265.
The fastest way to travel from Rome to Santander is by flight with an average journey time of 3h 3m.
Other travel options to Santander take longer:
Bus takes on average 38h 5m.
It's helpful to compare your options as there are 2 ways to travel between Rome and Santander including taking a bus and flight.
We recommend using the flight as it is the most popular way to get from Rome to Santander among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Rome to Santander Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:25PM | Arrival Time 09:20AM | Duration 39h55 | Departure days Everyday | Cheapest price $158 |
Operator FlixBus | Departure Time 07:35PM | Arrival Time 09:20AM | Duration 37h45 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $180 |
Operator FlixBus | Departure Time 09:55PM | Arrival Time 09:20AM | Duration 35h25 | Departure days Mon, Tue, Thu, Sun | Cheapest price $163 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 09:20AM | Duration 34h35 | Departure days Sat | Cheapest price $148 |
Live departures
Rome to Santander bus times
The table below shows live departures for Rome to Santander buses for today, Sunday, August 16. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus · FlixBus · FlixBus | 9:55 PM Roma, Autostazione Tiburtina | 35h25 | 9:20 AM Santander, Estación de Autobuses | 3 transfers | |
| Monday, August 17 | |||||
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 39h55 | 9:20 AM Santander, Estación de Autobuses | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 7:35 PM Roma, Autostazione Tiburtina | 37h45 | 9:20 AM Santander, Estación de Autobuses | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Santander by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Rome to Santander
Italy
Spain
Buses from Rome to Santander run on average 2 times per day, taking around 38h 5m. Cheap bus tickets for this journey start at $105 but you can travel from only $72 by flight.
The earliest bus runs at 09:25, the last at 22:45. The fastest bus covers the 833 miles (1341 km) distance in 35h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $72
Distance 833 miles (1341 km) |
Average bus duration 38h 5m |
Cheapest ticket price $105 |
Buses per day 2 |
Fastest bus 35h 15m |
First bus 9:25 AM |
Last bus 10:45 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Sat |
Least Busy Day Sun |
Best time to book 56 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $72
Complete guide to Santander
Things to do in Santander
Discover the best of Santander — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Santander trip today.
- Must visit
Museo Marítimo del Cantábrico
Excellent maritime museum covering Cantabrian seafaring, ecology, fishing, and naval history with aquariums and family-friendly displays.
- Recommended
MAS | Museo de Arte Moderno y Contemporáneo de Santander y Cantabria
Art museum focused on Cantabrian and Spanish painting, offering a compact but rewarding overview in a central historic setting.
- Must visit
Península de La Magdalena
Iconic peninsula park with palace grounds, beaches, mini-zoo area, and scenic walking routes. One of Santander’s essential outings.
- Must visit
Paseo de Pereda
Elegant seafront promenade linking gardens, monuments, and bay views. Ideal for a first walk through central Santander.
- Must visit
Cabo Mayor
Dramatic headland viewpoint with cliffs, lighthouse scenery, and walking trails. A favorite for sunsets and Atlantic panoramas.
- Gluten-free
Anchoas De Cantabria
Cantabrian anchovies cured in salt or olive oil. Santander is famous for high-quality bocarte landed on this coast and served as a prized tapa.
Merluza En Salsa Verde
Fresh hake with green sauce, usually with garlic, parsley, fish stock, peas and clams. A classic northern coastal dish tied to local fishing traditions.
- Gluten-free
Cocido Montañés
Mountain stew from Cantabria with white beans, collard greens and pork products. Hearty inland cooking that is iconic across the region.
Cenador De Amos
Refined Michelin-starred dining focused on seasonal Cantabrian products. Elegant setting and creative tasting menus with strong local identity.
El Serbal
Well-known dining room specializing in grilled fish and Cantabrian seafood. Smart but relaxed atmosphere with a strong local reputation.
Casa Lita
Established seafood restaurant known for fresh fish, shellfish and classic Santander cooking. Traditional atmosphere near the seafront.
Euro (€)
Moderate for Spain. Hotels and dining are usually cheaper than Madrid or Barcelona, while local transit and casual meals stay fairly affordable for tourists.
Average meal costs
- Budget
- €8-12 for fast food or a simple lunch.
- Mid-range
- €18-30 per person for a restaurant meal.
- Fine dining
- €50+ per person for upscale dining.
- Coffee
- €1.50-3 for coffee or cappuccino.
Tipping culture
Tipping is modest. Round up or leave 5-10% in restaurants for good service, small change in cafes, and round up taxi fares.
FAQs: Bus from Rome to Santander
Find answers to the most common questions about traveling from Rome to Santander by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santander, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Rome to Santander can start from as little as $105 when you book in advance. The average bus ticket price for Rome to Santander is $171 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Rome to Santander is 35h 15m to travel the 833 miles (1341 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Rome to Santander leaves at 9:25 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rome to Santander leaves at 10:45 PM.
When departing from Rome , you have various bus station options to start your journey from including Roma, Autostazione (Metro Anagnina), Roma, Autostazione Tiburtina . When arriving in Santander , you can end your journey in bus stations like Santander, Estación de Autobuses .Passengers board the bus most frequently from Roma, Autostazione (Metro Anagnina), which is located around away from the city centre, and they get off the bus at Santander, Estación de Autobuses, located 0 away from the city centre.
A trip to Santander from Rome is worth doing but not as a day trip with a journey time of 35h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Rome to Santander is February.
It's helpful to compare your options as there are 2 ways to travel between Rome and Santander including taking a bus and flight.
No, the bus from Rome to Santander has no accessibility options.
No, there are no bathrooms on board the bus from Rome to Santander.
Some of the most interesting sights to explore in Santander are:
- Palacio de la Magdalena, a historic royal palace set on a peninsula offering stunning views and guided tours
- Centro Botín, a modern art center designed by Renzo Piano featuring exhibitions and cultural events
- Playa del Sardinero, a popular beach known for its golden sands and vibrant promenade
- Museo Marítimo del Cantábrico, a maritime museum showcasing marine life and naval history
- Jardines de Piquío, beautifully landscaped gardens offering a peaceful retreat with ocean views.
The best things to do in Santander include:
- Santander Cathedral, a Gothic-style cathedral with impressive architecture and historical significance
- Parque de Mataleñas, a scenic park ideal for hiking and enjoying nature
- Mercado de la Esperanza, a bustling market where you can experience local culture and cuisine
- Paseo de Pereda, a picturesque promenade perfect for a leisurely stroll along the waterfront
- Gran Casino del Sardinero, a historic casino offering entertainment and a glimpse into the city's glamorous past.
No, bikes are not allowed on board the bus from Rome to Santander.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Rome to Santander.
No, luggage for the bus from Rome to Santander needs to be booked in addition.
No, there are no additional luggage options for the bus from Rome to Santander.
Unfortunately, pets are not allowed on the bus from Rome to Santander.
No, there are no USB plugs on board the bus from Rome to Santander.
No, there is no WiFi on board the bus from Rome to Santander.
Since both Rome and Santander are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Rome to Santander among Omio's users.
Spain uses the euro (€) as its currency. Travelers can use both cash and cards, but cards are widely accepted in cities and tourist areas, while cash may be preferred for small purchases, markets, and rural locations.
In Santander, travelers should be cautious of pickpocketing, especially in crowded areas such as public transport and popular tourist spots. Scams involving overcharging or unofficial taxi services can occur, so it's recommended to use licensed taxis and agree on fares beforehand. Additionally, travelers should be wary of distraction techniques used by thieves in busy markets or near attractions. Staying alert and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Rome to Santander
Most Rome to Santander buses use the Roma, Autostazione (Metro Anagnina) to Santander, Estación de Autobuses station pair. Use this guide to compare Rome and Santander bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Rome
Arrival bus stations in Santander
Roma, Autostazione (Metro Anagnina)Rome Anagnina, Via Tuscolana, 173
City-centre transport
Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre
BusRome Fiumicino, Scario · 31m · $1
nMA · 38m · $2 · every ~4 min
SubwayMea · 24m · $2 · every ~29 min
Shuttle31m · $12
Roma, Autostazione TiburtinaLargo Guido Mazzoni, snc, 00162 Roma RM, Italy
City-centre transport
Getting to Roma, Autostazione Tiburtina from Rome city centre
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Bus490, 495 · 16m · $2 · every ~22 min
SubwayMeb · 7m · $2 · every ~15 min
Roma, Autostazione Tiburtina bus station facilities and services
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafes and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Roma, Autostazione Tiburtina.
Parking, taxis and toilets
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Santander, Estación de AutobusesSantander Bus Station, Calle Navas de Tolosa 2, 39002
More options for your journey from Rome to Santander
Here are some other resources that might have the information you need
Most popular buses to and from Santander and Rome
Most popular bus connections to Santander
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