Travel Information
Compare bus and flight for Rome to Santander
Omio recommends booking the flight as it is the most popular option from Rome to Santander among Omio's users. If you are prioritising price take the flight with prices starting from $73. For those with little time consider booking a flight which can get you there in 3h 3m. In case you are seeking to minimise your carbon footprint the flight is your best bet as it emits only 4.0 - 8.0kg. The ticket price range depends on the travel mode: a flight costs an average of $73, and a flight costs an average of $73.
Distance: 833 miles (1341 km)
Compare flight with
Most popular Flight | Driving |
|---|---|
$265 Average price Cheapest | $564 Average price (fuel + tolls) |
6h 3m Average total duration Fastest 3h 3m Onboard + 3h 0m Additional time* | 18h 0m Average total duration (door-to-door) |
4.0 - 8.0kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Rome to Santander:
A bus is $94 (€76) less than a flight for this route with tickets for a flight from Rome to Santander costing on average $265 (€215).
Other travel options to Santander take longer:
Bus takes on average 38h 5m.
Travel optionsfrom Rome to Santander
How to get from Rome to Santander by train, bus or flight.
Our recommendation
The best way to travel from Rome to Santander is by taking a bus because it’s the best combination of price and speed.
3:25 PM39h55Rome7:20 AMSantander$1231One-way0 transfers
Cheapest
3:25 PM39h55Rome7:20 AMSantander$1231One-way0 transfers
Fastest
7:55 PM35h25Rome7:20 AMSantander$2361One-way0 transfers
Other options
4:25 PM39h55Rome8:20 AMSantander$1301One-way0 transfers
6:35 PM37h45Rome8:20 AMSantander$1401One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Rome to Santander
Travel to Santander easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Rome to Santander.

This is compared to other travel options from Rome to Santander:
A bus is $94 (€76) less than a flight for this route with tickets for a flight from Rome to Santander costing on average $265 (€215).
Other travel options to Santander take longer:
Bus takes on average 38h 5m.
- Around 10 flights per day.
- Around 2 buses per day.
However, we recommend checking specific travel dates for your route between Rome and Santander as scheduled services by bus and flight can vary by season or day of the week.
- Flights mostly depart from Rome Leonardo da Vinci Fiumicino Airport and arrive in Santander Airport.
- Buses mostly depart from Roma, Autostazione (Metro Anagnina) and arrive in Santander, Estación de Autobuses.
- Travel with Vueling, Malta Air, Ryanair, Iberia, GetJet Airlines to go to Santander by flight.
- 0 direct flights per day with Malta Air, Ryanair.
Travelling from Rome to Santander: related information
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