The cheapest and fastest buses from Pueblo, CO to San Luis Obispo, CA
Cheapest price
$319
Average price
$421
Fastest journey
1 d 6 h 15 m
Average duration
1 d 16 h 5 m
Buses per day
2
Distance
1465 km
The best way to find a cheap bus ticket from Pueblo, CO to San Luis Obispo, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pueblo, CO to San Luis Obispo, CA will cost around $421 if you buy it on the day, but the cheapest tickets can be found for only $319.
It's difficult to get from Pueblo, CO to San Luis Obispo, CA without transferring at least 2 times.




Live departures
Pueblo, CO to San Luis Obispo, CA bus times
The table below shows live departures for Pueblo, CO to San Luis Obispo, CA buses for tomorrow, Friday, November 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:50 AM Pueblo, CO | 30h15 | 4:05 PM San Luis Obispo, CA | 3 transfers | |
![]() | 2:10 PM Pueblo, CO | 49h55 | 4:05 PM San Luis Obispo, CA | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pueblo, CO to San Luis Obispo, CA by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Pueblo, CO to San Luis Obispo, CA
Buses from Pueblo, CO to San Luis Obispo, CA run on average 2 times per day, taking around 38h 7m. Cheap bus tickets for this journey start at $322 (€262) if you book in advance.
The earliest bus runs at 09:50, the last at 14:10. The fastest bus covers the 910 miles (1465 km) distance in 30h 15m.
Distance 910 miles (1465 km) |
Average bus duration 38h 7m |
Cheapest ticket price $322 (€262) |
Buses per day 2 |
Fastest bus 30h 15m |
First bus 09:50 |
Last bus 14:10 |
Bus providers: Omnibus Express, Greyhound from Pueblo, CO to San Luis Obispo, CAYou can travel by bus between Pueblo, CO to San Luis Obispo, CA with Omnibus Express, Greyhound for as low as $322 (€262). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
Omnibus Express
FAQs: Bus from Pueblo, CO to San Luis Obispo, CA
Find answers to the most common questions about traveling from Pueblo, CO to San Luis Obispo, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Luis Obispo, CA, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Bubblegum Alley, a narrow alleyway famous for its walls covered in layers of chewed gum left by visitors
- Mission San Luis Obispo de Tolosa, a historic Spanish mission founded in 1772 with a museum and beautiful gardens
- Bishop Peak, a popular hiking destination offering panoramic views of the city and surrounding landscapes
- San Luis Obispo Museum of Art, a contemporary art museum showcasing works by regional and national artists
- Avila Beach, a nearby coastal spot known for its sandy shores and scenic pier.
- Stroll through Downtown SLO, a vibrant area with shops, restaurants, and the famous Thursday Night Farmers' Market
- Attend a performance at the Fremont Theater, a historic venue known for its art deco architecture and live events
- Visit the San Luis Obispo Children's Museum, offering interactive exhibits and activities for kids
- Explore the local wineries and vineyards, enjoying tastings and tours in the Edna Valley wine region
- Discover the natural beauty of Montana de Oro State Park, with its rugged cliffs, secluded beaches, and scenic hiking trails.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Pueblo, CO to San Luis Obispo, CA, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Pueblo, CO to San Luis Obispo, CA
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