The cheapest and fastest buses from Portland, ME to Harrisburg, PA
Cheapest price
$196
Average price
$196
Fastest journey
12 h 40 m
Average duration
12 h 40 m
Buses per day
1
Distance
665 km
The best way to find a cheap bus ticket from Portland, ME to Harrisburg, PA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Portland, ME to Harrisburg, PA will cost around $196 if you buy it on the day, but the cheapest tickets can be found for only $196.
Of the 1 buses that leave Portland, ME for Harrisburg, PA on Mon, Mar 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Mar 23 the direct buses cover the 665 km distance in an average of 12 h 40 m but if you time it right, some buses will get you there in just 12 h 40 m .
On Mon, Mar 23 the slowest buses will take 12 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Portland, ME to Harrisburg, PA
Omio recommends booking the bus as it is the most popular option from Portland, ME to Harrisburg, PA among Omio's users. If you are prioritising price take the bus with prices starting from $93. For those with little time consider booking a flight which can get you there in 6h 8m. The ticket price range depends on the travel mode: a bus costs an average of $93, and a flight costs an average of $419.
Distance: 413 miles (665 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$159 Average price Cheapest | $186 Average price | $429 Average price |
13h 10m Average total duration 12h 40m Onboard + 30m Additional time* | 34h 11m Average total duration 33h 41m Onboard + 30m Additional time* | 9h 8m Average total duration Fastest 6h 8m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Compare prices and tickets Portland, ME to Harrisburg, PA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Mar 29
Journey information
Overview: Bus from Portland, ME to Harrisburg, PA
Buses from Portland, ME to Harrisburg, PA run on average 5 times per day, taking around 12h 40m. Cheap bus tickets for this journey start at $93 (€75) if you book in advance.
The earliest bus runs at 03:05, the last at 23:20. The fastest bus covers the 413 miles (665 km) distance in 12h 40m.
Distance 413 miles (665 km) |
Average bus duration 12h 40m |
Cheapest ticket price $93 (€75) |
Buses per day 5 |
Fastest bus 12h 40m |
First bus 03:05 |
Last bus 23:20 |
FAQs: Bus from Portland, ME to Harrisburg, PA
Find answers to the most common questions about traveling from Portland, ME to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

- Pennsylvania State Capitol, an architectural marvel featuring a grand dome and exquisite interior murals
- National Civil War Museum, a comprehensive museum offering insights into the American Civil War with extensive exhibits
- The State Museum of Pennsylvania, showcasing the state's history, art, and natural sciences through diverse collections
- Fort Hunter Mansion and Park, a historic site with preserved buildings and beautiful grounds reflecting 18th and 19th-century life
- Wildwood Park, a nature preserve offering trails and a nature center for wildlife observation and environmental education.
- City Island, a recreational area featuring sports facilities, walking trails, and riverboat cruises
- Whitaker Center for Science and the Arts, a venue offering interactive science exhibits and live performances
- Broad Street Market, one of the oldest continuously operating farmers' markets in the country, offering diverse local foods and goods
- Susquehanna Art Museum, presenting contemporary art exhibitions and educational programs
- Riverfront Park, ideal for walking, biking, and enjoying views of the Susquehanna River.
popular bus stations
Popular bus stations from Portland, ME to Harrisburg, PA
Most popular bus connections from Portland, ME
More options for your journey from Portland, ME to Harrisburg, PA
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