Travel Information
Compare bus for Portland, ME to Harrisburg, PA
Omio recommends booking the train as it is the most popular option from Portland, ME to Harrisburg, PA among Omio's users. If you are prioritising price take the bus with prices starting from €71. For those with little time consider booking a flight which can get you there in 3h 4m. The ticket price range depends on the travel mode: a bus costs an average of €71, and a flight costs an average of €324.
Distance: 413 miles (665 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€71 Average price Cheapest | €160 Average price | €324 Average price |
13h 10m Average total duration 12h 40m Onboard + 30m Additional time* | 23h 26m Average total duration 22h 56m Onboard + 30m Additional time* | 6h 4m Average total duration Fastest 3h 4m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Journey information
Overview: Bus from Portland, ME to Harrisburg, PA
Buses from Portland, ME to Harrisburg, PA run on average 5 times per day, taking around 12h 40m. Cheap bus tickets for this journey start at $87 (€71) if you book in advance.
The earliest bus runs at 03:05, the last at 23:20. The fastest bus covers the 413 miles (665 km) distance in 12h 40m.
Distance 413 miles (665 km) |
Average bus duration 12h 40m |
Cheapest ticket price $87 (€71) |
Buses per day 5 |
Fastest bus 12h 40m |
First bus 03:05 |
Last bus 23:20 |
FAQs: Bus from Portland, ME to Harrisburg, PA
Find answers to the most common questions about traveling from Portland, ME to Harrisburg, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Harrisburg, PA, this guide helps you travel smarter and with confidence.

- Pennsylvania State Capitol, an architectural marvel featuring a grand dome and exquisite interior murals
- National Civil War Museum, a comprehensive museum offering insights into the American Civil War with extensive exhibits
- The State Museum of Pennsylvania, showcasing the state's history, art, and natural sciences through diverse collections
- Fort Hunter Mansion and Park, a historic site with preserved buildings and beautiful grounds reflecting 18th and 19th-century life
- Wildwood Park, a nature preserve offering trails and a nature center for wildlife observation and environmental education.
- City Island, a recreational area featuring sports facilities, walking trails, and riverboat cruises
- Whitaker Center for Science and the Arts, a venue offering interactive science exhibits and live performances
- Broad Street Market, one of the oldest continuously operating farmers' markets in the country, offering diverse local foods and goods
- Susquehanna Art Museum, presenting contemporary art exhibitions and educational programs
- Riverfront Park, ideal for walking, biking, and enjoying views of the Susquehanna River.
To find the cheapest bus tickets for your trip from Portland, ME to Harrisburg, PA, follow these tips:
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Popular bus stations from Portland, ME to Harrisburg, PA
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