Travel Information
Compare train, bus, and flight for Plzeň to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Plzeň to Frankfurt am Main among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $47 For those with little time, consider booking a flight, which has an average total journey time of 4h 45m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $47, while a flight costs an average of $365.
Distance: 210 miles (338 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$109 Average price | $47 Average price Cheapest | $365 Average price | $92 Average price (fuel + tolls) |
5h 57m Average total duration 5h 27m Onboard + 30m Additional time* | 6h 51m Average total duration 6h 21m Onboard + 30m Additional time* | 4h 45m Average total duration Fastest 2h 45m Onboard + 2h 0m Additional time* | 3h 58m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.8kg CO2 emissions | 1.0 - 2.0kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Plzeň to Frankfurt am Main:
A bus is $63 less than a train for this route with tickets for a train from Plzeň to Frankfurt am Main costing on average $109.
A bus is $319 less than a flight for this route with tickets for a flight from Plzeň to Frankfurt am Main costing on average $365.
Other travel options to Frankfurt am Main take longer:
Train takes on average 5h 57m.
Bus takes on average 6h 51m.
Tickets start at around $109 compared to roughly $92 in fuel and tolls — a saving of about $-17.48. The journey takes 5h 27m versus 3h 58m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Travel optionsfrom Plzeň to Frankfurt am Main
How to get from Plzeň to Frankfurt am Main by train, bus or flight.
Our recommendation
The best way to travel from Plzeň to Frankfurt am Main is by taking a bus because it’s the best combination of price and speed.
FlixBus12:20 PM7h05Plzeň, Centrální Autobusové Nádraží7:25 PMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$291One-way0 transfers
Cheapest
FlixBus12:20 PM7h05Plzeň, Centrální Autobusové Nádraží7:25 PMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)$291One-way0 transfers
Fastest
DE441012:00 PM1h00Prague Vaclav Havel Airport1:00 PMFrankfurt am Main Airport$1631One-way0 transfers
Other options
R 756 · Os 7554 · Bus RB35 · 40937:40 PM11h57Plzen hl.n.7:37 AMFrankfurt (Main) Hbf$451One-way7 transfers
EX 356 · 3572 · ICE 6201:10 PM5h52Plzen hl.n.7:02 PMFrankfurt (Main) Hbf$471One-way2 transfers
EX 352 · 3580 · ICE 5225:10 PM6h10Plzen hl.n.11:20 PMFrankfurt (Main) Hbf$471One-way2 transfers
FlixBus12:20 PM6h35Plzeň, Centrální Autobusové Nádraží6:55 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$291One-way0 transfers
FlixBus · FlixBus4:40 PM7h10Plzeň, Centrální Autobusové Nádraží11:50 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$311One-way1 transfer
FlixBus · FlixBus1:20 AM8h00Plzeň, Centrální Autobusové Nádraží9:20 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)$311One-way1 transfer
LH14016:35 PM1h10Prague Vaclav Havel Airport7:45 PMFrankfurt am Main Airport$941One-way0 transfers
LH13972:20 PM1h10Prague Vaclav Havel Airport3:30 PMFrankfurt am Main Airport$941One-way0 transfers
LH139511:30 AM1h10Prague Vaclav Havel Airport12:40 PMFrankfurt am Main Airport$941One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Plzeň to Frankfurt am Main
Travel to Frankfurt am Main easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Plzeň to Frankfurt am Main.

This is compared to other travel options from Plzeň to Frankfurt am Main:
A bus is $63 less than a train for this route with tickets for a train from Plzeň to Frankfurt am Main costing on average $109.
A bus is $319 less than a flight for this route with tickets for a flight from Plzeň to Frankfurt am Main costing on average $365.
Other travel options to Frankfurt am Main take longer:
Train takes on average 5h 57m.
Bus takes on average 6h 51m.
- Around 55 flights per day.
- Around 14 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Plzeň and Frankfurt am Main as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Plzen hl.n. and arrive in Frankfurt (Main) Hbf.
- Buses mostly depart from Plzeň, Centrální Autobusové Nádraží and arrive in Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof).
- Travel with Lufthansa, Lufthansa Cityline, KLM Cityhopper, Swiss, Brussels Airlines, Condor Flugdienst, KLM, Qatar Airways, Air Dolomiti, Austrian Airlines, Air Baltic, Helvetic Airways, Lot Polish Airlines, British Airways, Edelweiss Air to go to Frankfurt am Main by flight.
- Travel with Deutsche Bahn, České dráhy to go to Frankfurt am Main by train.
- Travel with FlixBus to go to Frankfurt am Main by bus.
- 8 direct flights per day with Lufthansa, Condor Flugdienst, Air Dolomiti.
- 2 direct buses per day with FlixBus.
Travelling from Plzeň to Frankfurt am Main: related information
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