- Must visit
Edison and Ford Winter Estates
Historic riverfront estate museum with Thomas Edison and Henry Ford homes, gardens, and a large inventions museum. One of Fort Myers' signature cultural attractions.
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Travel Information
Compare bus, train, and flight for North Charleston, SC to Fort Myers, FL
Omio recommends booking the train as it is the most popular option from North Charleston, SC to Fort Myers, FL among Omio's users. If you are prioritising price take the train with prices starting from $167. For those with little time consider booking a flight which can get you there in 5h 36m. The ticket price range depends on the travel mode: a train costs an average of $167, and a flight costs an average of $132.
Distance: 446 miles (719 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$234 Average price | $172 Average price Cheapest | $327 Average price |
23h 35m Average total duration 23h 5m Onboard + 30m Additional time* | 14h 11m Average total duration 13h 41m Onboard + 30m Additional time* | 8h 36m Average total duration Fastest 5h 36m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from North Charleston, SC to Fort Myers, FL is a train with an average price of $172 (€140).
This is compared to other travel options from North Charleston, SC to Fort Myers, FL:
A train is $62 (€51) less than a bus for this route with tickets for a bus from North Charleston, SC to Fort Myers, FL costing on average $234 (€192).
A train is $155 (€127) less than a flight for this route with tickets for a flight from North Charleston, SC to Fort Myers, FL costing on average $327 (€268).
The fastest way to travel from North Charleston, SC to Fort Myers, FL is by flight with an average journey time of 5h 36m.
Other travel options to Fort Myers, FL take longer:
Train takes on average 13h 41m.
Bus takes on average 23h 5m.
It's helpful to compare your options as there are 3 ways to travel between North Charleston, SC and Fort Myers, FL including taking a bus, train, and flight.
We recommend using the train as it is the most popular way to get from North Charleston, SC to Fort Myers, FL among Omio's users.
North Charleston, SC to Fort Myers, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:15PM | Arrival Time 02:20PM | Duration 23h05 | Departure days Fri | Cheapest price $158 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 03:20PM | Duration 23h05 | Departure days Tue | Cheapest price $311 |
Compare prices and tickets North Charleston, SC to Fort Myers, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from North Charleston, SC to Fort Myers, FL
USAUSA
Buses from North Charleston, SC to Fort Myers, FL run on average 3 times per day, taking around 23h 5m. Cheap bus tickets for this journey start at $158 (€129) but you can travel from only $132 (€108) by flight.
The earliest bus runs at 04:56, the last at 19:37. The fastest bus covers the 446 miles (719 km) distance in 23h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $132 (€108)
Distance 446 miles (719 km) |
Average bus duration 23h 5m |
Cheapest ticket price $158 (€129) |
Buses per day 3 |
Fastest bus 23h 5m |
First bus 4:56 AM |
Last bus 7:37 PM |
Cheapest Month Apr |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Apr - Jun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $132 (€108)
Complete guide to Fort Myers
Things to do in Fort Myers
Discover the best of Fort Myers — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Fort Myers trip today.
- Recommended
IMAG History & Science Center
Family-friendly science and local history museum with interactive exhibits, aquariums, and hands-on learning. Popular for visitors with children.
- Recommended
Sidney & Berne Davis Art Center
Downtown visual and performing arts venue hosting exhibitions, events, and community programming in a restored historic federal building.
- Must visit
Fort Myers River District
The city's most popular walkable historic area, with brick streets, murals, shops, galleries, and nightlife. The top area to explore on foot.
- Must visit
Manatee Park
Seasonal waterfront park famous for winter manatee viewing, boardwalks, and kayak access. Widely shared on social media during cooler months.
- Must visit
Six Mile Cypress Slough Preserve
Popular nature preserve with a scenic boardwalk through wetlands, wildlife spotting, and strong appeal among photographers and nature lovers.
- Gluten-free
Stone Crab Claws
A Southwest Florida seasonal specialty, usually served chilled with mustard sauce. They are prized for sweet, firm meat and are strongly associated with Gulf Coast seafood culture.
Grouper Sandwich
A classic Florida coastal dish made with fresh local grouper, often grilled, blackened, or fried on a bun. It is a staple at waterfront restaurants around Fort Myers.
Conch Fritters
Fritters made with chopped conch in a seasoned batter, reflecting Caribbean and old Florida influences common in Southwest Florida seafood menus.
The Veranda
An established downtown fine-dining restaurant known for Southern-influenced cuisine, steaks, and seafood served in historic house-style rooms with a romantic atmosphere.
Doc Ford's Rum Bar & Grille
A popular Florida casual restaurant known for seafood, Yucatan-style flavors, and rum drinks in a lively, polished setting.
Dixie Fish Company
A casual, well-known seafood restaurant near the water, valued for fresh Gulf seafood and an old-Florida fish-house feel.
United States Dollar
Moderate by U.S. standards. Casual dining is affordable, but beach areas, hotels, and seasonal travel can raise costs noticeably.
Average meal costs
- Budget
- USD 10-18 for fast food or a casual lunch.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 60-120+ per person at upscale restaurants.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% in restaurants; 20%+ for excellent service. Bartenders: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 2-5. Not usually needed for fast food.
FAQs: Bus from North Charleston, SC to Fort Myers, FL
Find answers to the most common questions about traveling from North Charleston, SC to Fort Myers, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Fort Myers, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from North Charleston, SC to Fort Myers, FL can start from as little as $158 (€129) when you book in advance. The average bus ticket price for North Charleston, SC to Fort Myers, FL is $234 (€192) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from North Charleston, SC to Fort Myers, FL is 23h 5m to travel the 446 miles (719 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from North Charleston, SC to Fort Myers, FL leaves at 4:56 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from North Charleston, SC to Fort Myers, FL leaves at 7:37 PM.
A trip to Fort Myers, FL from North Charleston, SC is worth doing but not as a day trip with a journey time of 23h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from North Charleston, SC to Fort Myers, FL is April.
It's helpful to compare your options as there are 3 ways to travel between North Charleston, SC and Fort Myers, FL including taking a bus, train, and flight.
No, there are no bathrooms on board the bus from North Charleston, SC to Fort Myers, FL.
No, the bus from North Charleston, SC to Fort Myers, FL has no accessibility options.
No, bikes are not allowed on board the bus from North Charleston, SC to Fort Myers, FL.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from North Charleston, SC to Fort Myers, FL.
No, luggage for the bus from North Charleston, SC to Fort Myers, FL needs to be booked in addition.
No, there are no additional luggage options for the bus from North Charleston, SC to Fort Myers, FL.
Unfortunately, pets are not allowed on the bus from North Charleston, SC to Fort Myers, FL.
No, there are no USB plugs on board the bus from North Charleston, SC to Fort Myers, FL.
No, there is no WiFi on board the bus from North Charleston, SC to Fort Myers, FL.
Since neither North Charleston, SC nor Fort Myers, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from North Charleston, SC to Fort Myers, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Fort Myers, FL, travelers should be cautious of petty theft, especially in crowded areas and on beaches. Common scams include overcharging by taxis or ride services and timeshare presentations that pressure visitors into high-cost deals. It's advisable to use official transportation options, keep valuables secure, and remain aware of surroundings to ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from North Charleston, SC to Fort Myers, FL
Most North Charleston, SC to Fort Myers, FL buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Fort Myers, Rosa Parks Transit Center station pair. Use this guide to compare North Charleston, SC and Fort Myers, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in North Charleston
Arrival bus stations in Fort Myers
Fort Myers, Rosa Parks Transit Center
City-centre transport
Getting to Fort Myers, Rosa Parks Transit Center from Fort Myers city centre
Bus10 · 7m · $4 · every ~1 min
Most popular bus connections from North Charleston, SC
More options for your journey from North Charleston, SC to Fort Myers, FL
Here are some other resources that might have the information you need
Most popular buses to and from Fort Myers, FL and North Charleston, SC
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