North Charleston, SC to Fort Myers, FL bus

Fri, Mar 20
+ Add return
FlixBus
Alsa
Costa Verde
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
FlixBus
Alsa
Costa Verde
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

Travel Information

Compare bus, train, and flight for North Charleston, SC to Fort Myers, FL

Omio recommends booking the train as it is the most popular option from North Charleston, SC to Fort Myers, FL among Omio's users. If you are prioritising price take the train with prices starting from $177. For those with little time consider booking a flight which can get you there in 4h 3m. The ticket price range depends on the travel mode: a train costs an average of $177, and a flight costs an average of $422.

Distance: 446 miles (719 km)

Compare bus with

Bus
Most popular
Train
Flight

$313

Average price

$177

Average price

Cheapest

$422

Average price

23h 35m

Average total duration

23h 5m

Onboard

+

30m

Additional time*

14h 11m

Average total duration

13h 41m

Onboard

+

30m

Additional time*

7h 3m

Average total duration

Fastest

4h 3m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Direct Options

Journey information

Overview: Bus from North Charleston, SC to Fort Myers, FL

USAUSA
USAUSA
Icon of bus

Buses from North Charleston, SC to Fort Myers, FL run on average 3 times per day, taking around 23h 5m. Cheap bus tickets for this journey start at $313 (€254) but you can travel from only $177 (€144) by train.

The earliest bus runs at 04:56, the last at 19:37. The fastest bus covers the 446 miles (719 km) distance in 23h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $177 (€144)
Distance
446 miles (719 km)
Average bus duration
23h 5m
Cheapest ticket price
$313 (€254)
Buses per day
3
Fastest bus
23h 5m
First bus
04:56
Last bus
19:37
High season
Oct - Dec
Low season
Jan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $177 (€144)

FAQs: Bus from North Charleston, SC to Fort Myers, FL

Find answers to the most common questions about traveling from North Charleston, SC to Fort Myers, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Fort Myers, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from North Charleston, SC to Fort Myers, FL can start from as little as $313 (€254) when you book in advance. The average bus ticket price for North Charleston, SC to Fort Myers, FL is $313 (€254) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from North Charleston, SC to Fort Myers, FL is 23h 5m to travel the 446 miles (719 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from North Charleston, SC to Fort Myers, FL leaves at 4:56 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from North Charleston, SC to Fort Myers, FL leaves at 7:37 PM.
A trip to Fort Myers, FL from North Charleston, SC is worth doing but not as a day trip with a journey time of 23h 5m each way. Check with Omio app the best way to travel.
It's helpful to compare your options as there are 3 ways to travel between North Charleston, SC and Fort Myers, FL including taking a bus, train, and flight.
No, the bus from North Charleston, SC to Fort Myers, FL has no accessibility options.
No, there are no bathrooms on board the bus from North Charleston, SC to Fort Myers, FL.
No, bikes are not allowed on board the bus from North Charleston, SC to Fort Myers, FL.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from North Charleston, SC to Fort Myers, FL.
No, luggage for the bus from North Charleston, SC to Fort Myers, FL needs to be booked in addition.
No, there are no additional luggage options for the bus from North Charleston, SC to Fort Myers, FL.
Unfortunately, pets are not allowed on the bus from North Charleston, SC to Fort Myers, FL.
No, there are no USB plugs on board the bus from North Charleston, SC to Fort Myers, FL.
No, there is no WiFi on board the bus from North Charleston, SC to Fort Myers, FL.

popular bus stations

Popular bus stations from North Charleston, SC to Fort Myers, FL

North Charleston
Fort Myers
Fort Myers, Rosa Parks Transit Center
information

More options for your journey from North Charleston, SC to Fort Myers, FL

Here are some other resources that might have the information you need

Most popular buses to and from Fort Myers, FL and North Charleston, SC

HomeBusesBuses in USABus tickets to Fort Myers, FLNorth Charleston, SC to Fort Myers, FL bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone