- Must visit
The Baltimore Museum of Art
Renowned museum with major collections spanning contemporary, African, Asian, and American art, plus a celebrated sculpture garden.
Cheapest price
$116
Average price
$121
Fastest journey
16 h 55 m
Average duration
18 h 48 m
Buses per day
2
Distance
774 km
The best way to find a cheap bus ticket from North Charleston, SC to Baltimore, MD is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from North Charleston, SC to Baltimore, MD will cost around $121 if you buy it on the day, but the cheapest tickets can be found for only $116.
It's difficult to get from North Charleston, SC to Baltimore, MD without transferring at least once.




Omio recommends booking the train as it is the most popular option from North Charleston, SC to Baltimore, MD among Omio's users. If you are prioritising price take the train with prices starting from $167. For those with little time consider booking a flight which can get you there in 7h 26m. The ticket price range depends on the travel mode: a train costs an average of $167, and a flight costs an average of $337.
Distance: 480 miles (774 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$185 Average price | $167 Average price Cheapest | $337 Average price | $109 Average price (fuel + tolls) |
16h 50m Average total duration 16h 20m Onboard + 30m Additional time* | 11h 31m Average total duration 11h 1m Onboard + 30m Additional time* | 10h 26m Average total duration Fastest 7h 26m Onboard + 3h 0m Additional time* | 8h 32m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from North Charleston, SC to Baltimore, MD:
A train is $18 less than a bus for this route with tickets for a bus from North Charleston, SC to Baltimore, MD costing on average $185.
A train is $169 less than a flight for this route with tickets for a flight from North Charleston, SC to Baltimore, MD costing on average $337.
Other travel options to Baltimore, MD take longer:
Train takes on average 11h 1m.
Bus takes on average 16h 20m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:30AM | Arrival Time 04:10AM | Duration 18h40 | Departure days Sun | Cheapest price $159 |
Operator Greyhound USA | Departure Time 11:15AM | Arrival Time 04:10AM | Duration 16h55 | Departure days Wed, Fri, Sat | Cheapest price $116 |
Operator Greyhound | Departure Time 02:20PM | Arrival Time 08:05AM | Duration 17h45 | Departure days Sun | Cheapest price $130 |
Operator Greyhound | Departure Time 03:15PM | Arrival Time 07:35AM | Duration 16h20 | Departure days Thu | Cheapest price $185 |
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from North Charleston, SC to Baltimore, MD run on average 3 times per day, taking around 16h 20m. Cheap bus tickets for this journey start at $185 but you can travel from only $167 by train.
The earliest bus runs at 00:25, the last at 23:45. The fastest bus covers the 480 miles (774 km) distance in 16h 20m.
Distance 480 miles (774 km) |
Average bus duration 16h 20m |
Cheapest ticket price $185 |
Buses per day 3 |
Fastest bus 16h 20m |
First bus 12:25 AM |
Last bus 11:45 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Apr - Jun |
Best time to book 56 days |
Discover the best of Baltimore, MD — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Baltimore, MD trip today.
Renowned museum with major collections spanning contemporary, African, Asian, and American art, plus a celebrated sculpture garden.
Museum campus known for visionary and outsider art, mosaics, and immersive installations in a distinctive Baltimore setting.
Free art museum with ancient, medieval, Renaissance, and Asian works in a landmark Mount Vernon building.
Baltimore's signature waterfront district with promenades, museums, ships, and skyline views; ideal for first-time visitors.
Historic cobblestone waterfront neighborhood known for pubs, views, brick rowhouses, and a lively local atmosphere.
Elegant cultural district with monuments, museums, and 19th-century architecture surrounding tree-lined squares.
Maryland blue crab steamed with bold spice blend, then cracked by hand. It is Baltimore’s signature seafood ritual, especially around the harbor and summer crab feasts.
A rich cream-based soup with blue crab meat, often seasoned with sherry and Old Bay. It is a classic Baltimore comfort dish found in many local seafood houses.
A tomato-based vegetable soup with blue crab meat and Old Bay. It is a regional favorite in Baltimore, balancing sweet crab flavor with savory broth.
Refined waterfront seafood restaurant known for crab cakes, oysters, and Chesapeake dishes. Upscale but approachable, with strong local reputation in Fells Point.
Celebrated fine dining restaurant in a converted rowhouse, known for elegant Mid-Atlantic tasting menus and polished service in a historic Baltimore setting.
Casual local favorite for pit beef, turkey, and ham sandwiches. It is a go-to stop for the Baltimore area’s signature barbecue style.
Moderate for a major US city; hotels can be pricey, but dining and transit are usually manageable for tourists.
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and spare change or $1 at cafes.
Find answers to the most common questions about traveling from North Charleston, SC to Baltimore, MD by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Baltimore, MD, this guide helps you travel smarter and with confidence.

Most North Charleston, SC to Baltimore, MD buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Baltimore, Haines St (Baltimore Downtown Bus Station) station pair. Use this guide to compare North Charleston, SC and Baltimore, MD bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need