- Must visit
Art Institute Of Chicago
One of the premier art museums in the US, known for Impressionist masterpieces, modern works, and the iconic bronze lions at its entrance.
Cheapest price
$271
Average price
$271
Fastest journey
1 d 5 h
Average duration
1 d 5 h
Buses per day
1
Distance
1203 km
The best way to find a cheap bus ticket from North Charleston, SC to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from North Charleston, SC to Chicago, IL will cost around $271 if you buy it on the day, but the cheapest tickets can be found for only $271.
Of the 1 buses that leave North Charleston, SC for Chicago, IL on Sun, Jun 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 1203 km distance in an average of 1 d 5 h but if you time it right, some buses will get you there in just 1 d 5 h .
On Sun, Jun 21 the slowest buses will take 1 d 5 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the flight as it is the most popular option from North Charleston, SC to Chicago, IL among Omio's users. If you are prioritising price take the train with prices starting from $242. For those with little time consider booking a flight which can get you there in 7h 12m. The ticket price range depends on the travel mode: a train costs an average of $242, and a flight costs an average of $230.
Distance: 747 miles (1203 km)
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$271 Average price | $327 Average price | $242 Average price Cheapest | $176 Average price (fuel + tolls) |
29h 30m Average total duration 29h 0m Onboard + 30m Additional time* | 10h 12m Average total duration Fastest 7h 12m Onboard + 3h 0m Additional time* | 37h 56m Average total duration 37h 26m Onboard + 30m Additional time* | 13h 35m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from North Charleston, SC to Chicago, IL:
A train is $29 (€24) less than a bus for this route with tickets for a bus from North Charleston, SC to Chicago, IL costing on average $271 (€222).
A train is $85 (€70) less than a flight for this route with tickets for a flight from North Charleston, SC to Chicago, IL costing on average $327 (€268).
Other travel options to Chicago, IL take longer:
Bus takes on average 29h 0m.
Train takes on average 37h 26m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound USA | Departure Time 11:15AM | Arrival Time 03:15PM | Duration 28h00 | Departure days Wed, Thu, Fri, Sat | Cheapest price $265 |
Operator Greyhound | Departure Time 04:15PM | Arrival Time 09:15PM | Duration 29h00 | Departure days Sun | Cheapest price $271 |
The table below shows live departures for North Charleston, SC to Chicago, IL buses for tomorrow, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:15 PM North Charleston, SC | 29h00 | 9:15 PM Chicago, IL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from North Charleston, SC to Chicago, IL run on average 2 times per day, taking around 29h 0m. Cheap bus tickets for this journey start at $271 (€222) but you can travel from only $230 (€189) by flight.
The earliest bus runs at 10:00, the last at 23:50. The fastest bus covers the 747 miles (1203 km) distance in 29h 0m.
Distance 747 miles (1203 km) |
Average bus duration 29h 0m |
Cheapest ticket price $271 (€222) |
Buses per day 2 |
Fastest bus 29h 0m |
First bus 10:00 AM |
Last bus 11:50 PM |
Cheapest Month Oct |
Cheapest Day Mon |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 21 days |
Discover the best of Chicago — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Chicago trip today.
One of the premier art museums in the US, known for Impressionist masterpieces, modern works, and the iconic bronze lions at its entrance.
Major natural history museum famous for Sue the T. rex, ancient cultures, and extensive science collections that appeal to both adults and children.
Large hands-on science museum in Hyde Park featuring a submarine, space exhibits, engineering displays, and immersive family-friendly experiences.
The city’s signature public space, home to Cloud Gate, gardens, events, and major skyline views that define modern Chicago.
Famous stretch of Michigan Avenue lined with historic buildings, shops, hotels, and frequent first-time visitor photo stops.
Highly popular waterfront promenade with architecture views, bridges, and one of the best urban walks in the city.
Chicago’s iconic thick-crust pizza baked in a deep pan, layered with cheese, toppings, and chunky tomato sauce. It is one of the city’s most famous comfort foods.
An all-beef hot dog on a poppy seed bun topped with mustard, onions, neon relish, tomato, pickle spear, sport peppers, and celery salt. It is a classic local street food.
Thinly sliced roast beef piled onto an Italian roll, often dipped in seasoned jus and topped with sweet peppers or giardiniera. It is a defining Chicago sandwich.
A historic old-school steakhouse serving steaks, chops, and classic Italian-American dishes in a traditional setting.
Chicago’s internationally acclaimed fine-dining restaurant known for highly inventive tasting menus and exceptional service.
A long-established Chicago favorite known for buttery deep-dish pizza and a casual, family-friendly atmosphere.
Moderate for a major U.S. city: casual food is manageable, but hotels, attractions, and downtown dining can be pricey.
Tip 18-20% in restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, and hotel staff a few dollars.
Find answers to the most common questions about traveling from North Charleston, SC to Chicago, IL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

Most North Charleston, SC to Chicago, IL buses use the Charleston, Gaynor Avenue (Greyhound Bus Station) to Chicago, Greyhound Bus Station station pair, with some services arriving at Chicago, Union Station (Amtrak). Use this guide to compare North Charleston, SC and Chicago, IL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need