- Must visit
Philadelphia Museum of Art
World-class art museum famous for major collections and the Rocky Steps. A top cultural stop with strong city views.
Cheapest, Fastest
Myrtle Beach, N Oak St (Bus Station)
Philadelphia Bus Station
$1391•One-way
2nd cheapest, 2nd Fastest
+
Myrtle Beach, N Oak St (Bus Station)
Philadelphia Bus Station
$1531•One-way
The cheapest and fastest busesfrom Myrtle Beach, SC to Philadelphia, PAShowing times and prices for Jul 15
Cheapest price
$139
Average price
$146
Fastest journey
15h 40m
Average duration
16h 15m
Buses per day
2
Distance
771 km
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Myrtle Beach, SC to Philadelphia, PA bus with Greyhound
Travel Information
Compare bus and flight for Myrtle Beach, SC to Philadelphia, PA
Omio recommends booking the bus as it is the most popular option from Myrtle Beach, SC to Philadelphia, PA among Omio's users. If you are prioritising price take the bus with prices starting from $86. For those with little time consider booking a flight which can get you there in 4h 36m. The ticket price range depends on the travel mode: a bus costs an average of $86, and a flight costs an average of $141.
Distance: 479 miles (771 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$115 Average price Cheapest | $259 Average price | $121 Average price (fuel + tolls) |
14h 35m Average total duration 14h 5m Onboard + 30m Additional time* | 7h 36m Average total duration Fastest 4h 36m Onboard + 3h 0m Additional time* | 8h 59m Average total duration (door-to-door) |
 Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Myrtle Beach, SC to Philadelphia, PA is a bus with an average price of $115 (€94).
This is compared to other travel options from Myrtle Beach, SC to Philadelphia, PA:
A bus is $144 (€118) less than a flight for this route with tickets for a flight from Myrtle Beach, SC to Philadelphia, PA costing on average $259 (€213).
The fastest way to travel from Myrtle Beach, SC to Philadelphia, PA is by flight with an average journey time of 4h 36m.
Other travel options to Philadelphia, PA take longer:
Bus takes on average 14h 5m.
It's helpful to compare your options as there are 2 ways to travel between Myrtle Beach, SC and Philadelphia, PA including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Myrtle Beach, SC to Philadelphia, PA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Myrtle Beach, SC to Philadelphia, PA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:45PM | Arrival Time 04:25AM | Duration 15h40 | Departure days Everyday | Cheapest price $94 |
Operator Greyhound | Departure Time 01:55PM | Arrival Time 06:45AM | Duration 16h50 | Departure days Tue | Cheapest price $94 |
Operator FlixBus | Departure Time 01:55PM | Arrival Time 06:45AM | Duration 16h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $135 |
Live departures
Myrtle Beach, SC to Philadelphia, PA bus times
The table below shows live departures for Myrtle Beach, SC to Philadelphia, PA buses for today, Wednesday, July 15. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · | 12:45 PM Myrtle Beach, N Oak St (Bus Station) | 15h40 | 4:25 AM Philadelphia Bus Station | 1 transfer | |
 FlixBus+ · · | 1:55 PM Myrtle Beach, N Oak St (Bus Station) | 16h50 | 6:45 AM Philadelphia Bus Station | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Myrtle Beach, SC to Philadelphia, PA by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Myrtle Beach, SC to Philadelphia, PA buses with Omio?
Greyhound as well as FlixBus offer buses services from Myrtle Beach, SC to Philadelphia, PA.
Omio is an official ticket reseller for all your travel options from Myrtle Beach, SC to Philadelphia, PA.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Myrtle Beach, SC to Philadelphia, PA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Myrtle Beach, SC to Philadelphia, PA.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Myrtle Beach, SC to Philadelphia, PA.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Myrtle Beach, SC to Philadelphia, PA.
Journey information
Overview: Bus from Myrtle Beach, SC to Philadelphia, PA
USAUSA
Buses from Myrtle Beach, SC to Philadelphia, PA run on average 4 times per day, taking around 14h 5m. Cheap bus tickets for this journey start at $86 (€71) if you book in advance.
The earliest bus runs at 00:50, the last at 23:15. The fastest bus covers the 479 miles (771 km) distance in 15h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 479 miles (771 km) |
Average bus duration 14h 5m |
Cheapest ticket price $86 (€71) |
Buses per day 4 |
Fastest bus 15h 30m |
First bus 12:50 AM |
Last bus 11:15 PM |
Cheapest Month Apr |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 1 day |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus from Myrtle Beach, SC to Philadelphia, PAYou can travel by bus between Myrtle Beach, SC to Philadelphia, PA with Greyhound, FlixBus for as low as $86 (€71). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
18h 50m
Cheapest Price
$101 (€83)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
15h 30m
Cheapest Price
$86 (€71)
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Philadelphia, PA
Things to do in Philadelphia, PA
Discover the best of Philadelphia, PA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Philadelphia, PA trip today.
- Must visit
The Franklin Institute
Hands-on science museum for all ages, known for interactive exhibits and the giant walk-through heart near the Parkway.
- Must visit
Barnes Foundation
Celebrated collection of Impressionist, Post-Impressionist, and modern works in an intimate gallery setting on the Parkway.
- Must visit
Independence National Historical Park
Historic district packed with foundational sites, cobblestone streets, and museums. The best base for first-time visitors.
- Must visit
Eakins Oval and Rocky Steps
Beloved park atop a hill with skyline views, trails, and the Rocky Steps approach. Great for walking and photography.
- Must visit
Rittenhouse Square
Walkable district of rowhouses, boutiques, and small parks. A classic local neighborhood for architecture and relaxed city strolling.
Philly Cheesesteak
A long roll packed with thin-sliced beef and melted cheese, often with fried onions. It is Philadelphia's signature street and comfort food.
- Vegetarian
- Vegan
Philadelphia Soft Pretzel
A soft pretzel with a distinct figure-eight twist and chewy texture. Sold by street vendors and bakeries, it is a classic Philadelphia snack.
Roast Pork Sandwich
A roast pork sandwich with garlicky pork, sharp provolone, and broccoli rabe. Many locals consider it the city's best traditional sandwich.
Vetri Cucina
Acclaimed fine dining restaurant by Chef Marc Vetri, known for refined Italian tasting menus and one of Philadelphia's top culinary experiences.
John's Roast Pork
Historic roast pork and cheesesteak shop in South Philadelphia, known for hearty sandwiches and a no-frills local atmosphere.
Rita's Italian Ice
Beloved local chain specializing in water ice and frozen custard. It is a go-to stop for a classic Philadelphia summer dessert.
US Dollar ($)
Moderate for a major US city. Hotels can be pricey in Center City, but dining and transit are often cheaper than New York or Washington.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a restaurant meal.
- Fine dining
- $75+ per person for upscale dining.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 18-20% in restaurants, 15-20% for taxis, and $1-2 per drink or cafe order if service is provided.
SEPTA
Get the appOfficial public transport app
Prices
- Single ticket
- $2.50
- Day pass
- $13.00
To the city center
Philadelphia Bus Terminal -> Philadelphia City Hall, Philadelphia, PA
- Distance
- 1 km
- Travel time
- 12 min
- SEPTA accepts contactless bank cards and mobile wallets on buses, trolleys, subways, and trains with Tap to Ride.
- Buy fares and plan trips in the official SEPTA app. Exact fare policies can vary by service, so check before boarding Regional Rail.
FAQs: Bus from Myrtle Beach, SC to Philadelphia, PA
Find answers to the most common questions about traveling from Myrtle Beach, SC to Philadelphia, PA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Philadelphia, PA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Myrtle Beach, SC to Philadelphia, PA can start from as little as $86 (€71) when you book in advance. The average bus ticket price for Myrtle Beach, SC to Philadelphia, PA is $115 (€94) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Myrtle Beach, SC to Philadelphia, PA is 15h 30m to travel the 479 miles (771 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Myrtle Beach, SC to Philadelphia, PA leaves at 12:50 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Myrtle Beach, SC to Philadelphia, PA leaves at 11:15 PM.
There are 4 buses a day from Myrtle Beach, SC to Philadelphia, PA which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Myrtle Beach, SC to Philadelphia, PA, you can count on Greyhound, FlixBus for the best way to get you to Philadelphia, PA. You can also check all possible bus companies who offer a service between Myrtle Beach, SC and Philadelphia, PA and compare the amenities they offer before buying a bus ticket.
A trip to Philadelphia, PA from Myrtle Beach, SC is worth doing but not as a day trip with a journey time of 15h 30m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Myrtle Beach, SC to Philadelphia, PA is April.
It's helpful to compare your options as there are 2 ways to travel between Myrtle Beach, SC and Philadelphia, PA including taking a bus and flight.
Yes, there are bathrooms on board the bus from Myrtle Beach, SC to Philadelphia, PA for bus company FlixBus, Greyhound.
Yes, the following accessibility options are available when taking the bus from Myrtle Beach, SC to Philadelphia, PA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Some of the most interesting sights to explore in Philadelphia, PA are:
- Liberty Bell, an iconic symbol of American independence housed in Liberty Bell Center
- Independence Hall, the birthplace of the United States where the Declaration of Independence and Constitution were signed
- Philadelphia Museum of Art, renowned for its vast collection of art and famous Rocky Steps
- Reading Terminal Market, a historic public market offering diverse food vendors and local specialties
- Eastern State Penitentiary, a former prison now a museum known for its grand architecture and historical significance.
The best things to do in Philadelphia, PA include:
- Liberty Bell, an iconic symbol of American independence located in the Liberty Bell Center
- Independence Hall, the historic site where the Declaration of Independence and the U.S. Constitution were debated and adopted
- Philadelphia Museum of Art, renowned for its vast collection of art and the famous Rocky Steps
- Reading Terminal Market, a bustling indoor market offering diverse food options and local specialties
- Philadelphia Zoo, America's first zoo featuring a wide variety of animals and interactive exhibits.
Whether you can cancel your bus ticket from Myrtle Beach, SC to Philadelphia, PA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Myrtle Beach, SC to Philadelphia, PA.
Yes, the following luggage options are included when booking a bus ticket from Myrtle Beach, SC to Philadelphia, PA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Myrtle Beach, SC to Philadelphia, PA:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Myrtle Beach, SC to Philadelphia, PA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Myrtle Beach, SC to Philadelphia, PA with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from Myrtle Beach, SC to Philadelphia, PA with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from Myrtle Beach, SC to Philadelphia, PA with the following bus company: FlixBus, Greyhound.
Since neither Myrtle Beach, SC nor Philadelphia, PA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Myrtle Beach, SC to Philadelphia, PA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Philadelphia, PA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Center City and tourist hotspots. Scams involving overpriced taxi rides or unlicensed transportation are common, so using reputable services or ride-sharing apps is advised. Travelers should also be wary of street vendors selling counterfeit goods and avoid displaying valuables openly to reduce risk. Staying aware of surroundings and using well-lit, populated routes enhances safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Myrtle Beach, SC to Philadelphia, PA
Most Myrtle Beach, SC to Philadelphia, PA buses use the Myrtle Beach, N Oak St (Bus Station) to Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) station pair, with some services arriving at Philadelphia, Schuylkill Ave (Cira Centre South). Use this guide to compare Myrtle Beach, SC and Philadelphia, PA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Myrtle Beach
Arrival bus stations in Philadelphia
Myrtle Beach, N Oak St (Bus Station)
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park)
Philadelphia, Schuylkill Ave (Cira Centre South)
Philadelphia, Greyhound Bus Station
City-centre transport
Getting to Philadelphia, Greyhound Bus Station from Philadelphia city centre
TrainAir, War, Wil, Med, Wtr, Lan, Pao, Nor, Che, Tre, Chw, Fox · 5m · $4 · every ~20 min
Bus17, 33, 44, 48, 62 · 2m · $4 · every ~34 min
SubwayL1 · 1m · $4 · every ~17 min
Most popular bus connections from Myrtle Beach, SC
More options for your journey from Myrtle Beach, SC to Philadelphia, PA
Here are some other resources that might have the information you need
Most popular buses to and from Philadelphia, PA and Myrtle Beach, SC
Most popular bus connections to Philadelphia, PA
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