Myrtle Beach, SC to Tampa, FL bus with FlixBus

Sun, Sep 06
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The cheapest and fastest buses from Myrtle Beach, SC to Tampa, FL

Showing times, prices and bookable tickets for Sep 06

Cheapest price on Sep 06

$99

Average ticket price on Sep 06

$104

Fastest journey on Sep 06

18 h

Average journey duration on Sep 06

23 h 23 m

Buses on Sep 06

3

Distance

724 km

Cheap tickets

The best way to find a cheap bus ticket from Myrtle Beach, SC to Tampa, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Myrtle Beach, SC to Tampa, FL will cost around $104 if you buy it on the day, but the cheapest tickets can be found for only $99.

Fast buses

It's difficult to get from Myrtle Beach, SC to Tampa, FL without transferring at least once.

  • Greyhound+FlixBusFlixBus
    12:40 PM18h00
    Myrtle Beach, N Oak St (Bus Station)
    6:40 AMTampa, USF Holly Drive (Central Plant), FL
    $991One-way
    1 transfer
  • Greyhound+FlixBusFlixBus
    12:40 PM18h30
    Myrtle Beach, N Oak St (Bus Station)
    7:10 AMTampa, Marion Transit Center
    $991One-way
    1 transfer
  • Greyhound · +FlixBusFlixBus · FlixBus
    12:45 PM33h40
    Myrtle Beach, N Oak St (Bus Station)
    10:25 PMTampa, Marion Transit Center
    $1151One-way
    4 transfers

Travel Information

Compare bus for Myrtle Beach, SC to Tampa, FL

Omio recommends booking the bus as it is the most popular option from Myrtle Beach, SC to Tampa, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $128 For those with little time, consider booking a bus, which has an average total journey time of 12h 40m. Average ticket prices depend on the travel mode: a bus costs an average of $128, while a bus costs an average of $128.

Distance: 449 miles (724 km)

Compare bus with

Most popular
Bus
Driving

$128

Average price

Cheapest

$108

Average price

(fuel + tolls)

12h 40m

Average total duration

Fastest

12h 10m

Onboard

+

30m

Additional time*

8h 38m

Average total duration

(door-to-door)

FlixBus

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

The cheapest way to travel from Myrtle Beach, SC to Tampa, FL is a bus with an average price of $128 (€104).
The fastest way to travel from Myrtle Beach, SC to Tampa, FL is by bus with an average journey time of 12h 10m.
Yes, you can take a bus between Myrtle Beach, SC and Tampa, FL.
We recommend using the bus as it is the most popular way to get from Myrtle Beach, SC to Tampa, FL among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $128 (€104) compared to roughly $108 (€88) in fuel and tolls — a saving of about $-19.72 (€-15.94). The journey takes 12h 10m versus 8h 38m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Myrtle Beach, SC to Tampa, FL Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
12:40PM
Arrival Time
06:40AM
Duration
18h00
Departure days
Tue, Wed, Thu, Fri, Sat, Sun
Cheapest price
$89
Operator
FlixBus
Departure Time
12:45PM
Arrival Time
10:25PM
Duration
33h40
Departure days
Tue, Wed, Thu, Fri, Sat, Sun
Cheapest price
$90
Operator
Greyhound
Departure Time
01:55PM
Arrival Time
12:45PM
Duration
22h50
Departure days
Mon
Cheapest price
$106

Live departures

Myrtle Beach, SC to Tampa, FL bus times

The table below shows live departures for Myrtle Beach, SC to Tampa, FL buses for today, Saturday, September 5. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound+FlixBusFlixBus12:40 PM Myrtle Beach, N Oak St (Bus Station)
18h00
6:40 AM Tampa, USF Holly Drive (Central Plant), FL1 transfer
Greyhound+FlixBusFlixBus12:40 PM Myrtle Beach, N Oak St (Bus Station)
18h30
7:10 AM Tampa, Marion Transit Center1 transfer
Greyhound · +FlixBusFlixBus · FlixBus12:45 PM Myrtle Beach, N Oak St (Bus Station)
33h40
10:25 PM Tampa, Marion Transit Center4 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Myrtle Beach, SC to Tampa, FL by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Sep 05
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Sep 11

Why should you book Myrtle Beach, SC to Tampa, FL buses with Omio?

FlixBus operates all buses services from Myrtle Beach, SC to Tampa, FL.
Omio is an official ticket reseller for all your travel options from Myrtle Beach, SC to Tampa, FL.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Journey information

Overview: Bus from Myrtle Beach, SC to Tampa, FL

USAUSA
USAUSA
Icon of bus

Buses from Myrtle Beach, SC to Tampa, FL run on average 2 times per day, taking around 12h 10m. Cheap bus tickets for this journey start at $87 (€70) if you book in advance.

The earliest bus runs at 06:10, the last at 22:35. The fastest bus covers the 449 miles (724 km) distance in 16h 5m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
449 miles (724 km)
Average bus duration
12h 10m
Cheapest ticket price
$87 (€70)
Buses per day
2
Fastest bus
16h 5m
First bus
6:10 AM
Last bus
10:35 PM
Cheapest Month
Sep
Cheapest Day
Sat
Best time to book
14 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Myrtle Beach, SC to Tampa, FLYou can travel by bus between Myrtle Beach, SC to Tampa, FL with FlixBus for as low as $87 (€70). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
16h 5m
Cheapest FlixBus Price
$87 (€70)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Complete guide to Tampa, FL

Things to do in Tampa, FL

Discover the best of Tampa, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tampa, FL trip today.

  • Must visit

Tampa Museum of Art

Major art museum on the Riverwalk with Greek and Roman antiquities, modern art, and a strong photography collection.

  • Must visit

Tampa Bay History Center

Engaging family-friendly museum exploring Tampa Bay history through exhibits on pirates, cigars, industry, and local communities.

  • Recommended

Henry B. Plant Museum

Fascinating history museum inside the former Tampa Bay Hotel, showcasing Gilded Age rooms, décor, and Florida tourism heritage.

United States dollar ($)

Moderate for U.S. beach cities: hotels can be high in peak season, but dining and local transport are usually manageable for most visitors.

Average meal costs

Budget
$10-18 for fast food or casual takeout.
Mid-range
$20-40 per person for a meal.
Fine dining
$60+ per person for upscale restaurants.
Coffee
$3-6 for coffee or cappuccino.

Tipping culture

Tip 15-20% at restaurants, 18-22% for great service. Taxis usually 10-15%. For cafes, small change or $1 per drink is common but optional.

FAQs: Bus from Myrtle Beach, SC to Tampa, FL

Find answers to the most common questions about traveling from Myrtle Beach, SC to Tampa, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tampa, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Myrtle Beach, SC to Tampa, FL can start from as little as $87 (€70) when you book in advance. The average bus ticket price for Myrtle Beach, SC to Tampa, FL is $128 (€104) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Myrtle Beach, SC to Tampa, FL is 16h 5m to travel the 449 miles (724 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Myrtle Beach, SC to Tampa, FL leaves at 6:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Myrtle Beach, SC to Tampa, FL leaves at 10:35 PM.
There are 2 buses a day from Myrtle Beach, SC to Tampa, FL which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Myrtle Beach, SC to Tampa, FL, you can count on FlixBus for the best way to get you to Tampa, FL. You can also check all possible bus companies who offer a service between Myrtle Beach, SC and Tampa, FL and compare the amenities they offer before buying a bus ticket.
When departing from Myrtle Beach, SC , you have various bus station options to start your journey from including Myrtle Beach, N Oak St (Bus Station) . When arriving in Tampa, FL , you can end your journey in bus stations like Tampa, Marion Transit Center, Tampa, USF Holly Drive (Central Plant), FL, Pinellas Park, Shoppes at Park Place - Shelter - D, Saint Petersburg, Central Avenue N / Dr Martin Luther King St Jr, FL .Passengers board the bus most frequently from Myrtle Beach, N Oak St (Bus Station), which is located around away from the city centre, and they get off the bus at Tampa, Marion Transit Center, located 0 away from the city centre.
A trip to Tampa, FL from Myrtle Beach, SC is worth doing but not as a day trip with a journey time of 16h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Myrtle Beach, SC to Tampa, FL is September.
Yes, you can take a bus between Myrtle Beach, SC and Tampa, FL.
Yes, the following accessibility options are available when taking the bus from Myrtle Beach, SC to Tampa, FL:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Myrtle Beach, SC to Tampa, FL for bus company FlixBus.
Some of the most interesting sights to explore in Tampa, FL are:
  • Busch Gardens Tampa Bay, a renowned theme park offering thrilling rides and animal encounters
  • The Florida Aquarium, a popular attraction featuring marine life exhibits and interactive experiences
  • Tampa Riverwalk, a scenic waterfront path with parks, museums, and dining options
  • Ybor City, a historic district known for its vibrant nightlife and Cuban culture
  • Tampa Museum of Art, showcasing contemporary and classical art in a modern architectural setting.
The best things to do in Tampa, FL include:
  • Visit the historic Henry B. Plant Museum, housed in a former luxury hotel with exhibits on the Gilded Age
  • Explore the vibrant Hyde Park Village, offering shopping, dining, and entertainment
  • Attend a Tampa Bay Buccaneers game at Raymond James Stadium for an exciting sports experience
  • Take a boat tour of Tampa Bay for stunning views and wildlife sightings
  • Enjoy a day at the beautiful Clearwater Beach, just a short drive from Tampa.
Whether you can cancel your bus ticket from Myrtle Beach, SC to Tampa, FL depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Myrtle Beach, SC to Tampa, FL.
Yes, the following luggage options are included when booking a bus ticket from Myrtle Beach, SC to Tampa, FL:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Myrtle Beach, SC to Tampa, FL:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Myrtle Beach, SC to Tampa, FL. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Myrtle Beach, SC to Tampa, FL with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Myrtle Beach, SC to Tampa, FL with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Myrtle Beach, SC to Tampa, FL with the following bus company: FlixBus.
Since neither Myrtle Beach, SC nor Tampa, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Myrtle Beach, SC to Tampa, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Tampa, FL, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and popular tourist spots like Ybor City and downtown. Common scams include overcharging by taxi or rideshare drivers and timeshare presentations that pressure visitors into costly purchases. Staying aware of surroundings and using licensed transportation can help avoid these issues.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Myrtle Beach, SC to Tampa, FL

Most Myrtle Beach, SC to Tampa, FL buses use the Myrtle Beach, N Oak St (Bus Station) to Tampa, Marion Transit Center station pair, with some services arriving at Tampa, USF Holly Drive (Central Plant). Use this guide to compare Myrtle Beach, SC and Tampa, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Myrtle Beach
Arrival bus stations in Tampa

Which Myrtle Beach, SC station do buses to Tampa, FL leave from?

Buses from Myrtle Beach, SC to Tampa, FL leave from Myrtle Beach, N Oak St (Bus Station). The station is from Myrtle Beach, SC city centre at Myrtle Beach Bus Station, 511 7th Ave N, Myrtle Beach, SC 29577, USA.
Myrtle Beach, N Oak St (Bus Station)Myrtle Beach Bus Station, 511 7th Ave N, Myrtle Beach, SC 29577, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Myrtle Beach, N Oak St (Bus Station) from Myrtle Beach city centre

TRUE

Myrtle Beach, N Oak St (Bus Station) bus station facilities and services

Myrtle Beach, N Oak St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Myrtle Beach, N Oak St (Bus Station). ATMs are available at Myrtle Beach, N Oak St (Bus Station).

Tickets and information

Ticket office support is available at Myrtle Beach, N Oak St (Bus Station).

Parking, taxis and toilets

Available at Myrtle Beach, N Oak St (Bus Station): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Myrtle Beach, N Oak St (Bus Station): Wheelchair accessible entry available.

More options for your journey from Myrtle Beach, SC to Tampa, FL

Here are some other resources that might have the information you need

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