- Must visit
Tampa Museum of Art
Major art museum on the Riverwalk with Greek and Roman antiquities, modern art, and a strong photography collection.
+
Myrtle Beach, N Oak St (Bus Station)
Tampa, Marion Transit Center
$2601•One-way
Cheapest, Fastest
+Myrtle Beach, N Oak St (Bus Station)
Tampa, USF Holly Drive (Central Plant), FL
$2581•One-way
The cheapest and fastest busesfrom Myrtle Beach, SC to Tampa, FLShowing times and prices for Jul 15
Cheapest price
$258
Average price
$259
Fastest journey
22h 50m
Average duration
23h 5m
Buses per day
2
Distance
620 km
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Myrtle Beach, SC to Tampa, FL bus with FlixBus
Travel Information
Compare bus and flight for Myrtle Beach, SC to Tampa, FL
Omio recommends booking the bus as it is the most popular option from Myrtle Beach, SC to Tampa, FL among Omio's users. If you are prioritising price take the bus with prices starting from $143. For those with little time consider booking a flight which can get you there in 1h 42m. The ticket price range depends on the travel mode: a bus costs an average of $143, and a flight costs an average of $241.
Distance: 449 miles (724 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$143 Average price Cheapest | $241 Average price | $106 Average price (fuel + tolls) |
12h 40m Average total duration 12h 10m Onboard + 30m Additional time* | 4h 42m Average total duration Fastest 1h 42m Onboard + 3h 0m Additional time* | 8h 38m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Myrtle Beach, SC to Tampa, FL is a bus with an average price of $143 (€118).
This is compared to other travel options from Myrtle Beach, SC to Tampa, FL:
A bus is $98 (€80) less than a flight for this route with tickets for a flight from Myrtle Beach, SC to Tampa, FL costing on average $241 (€198).
The fastest way to travel from Myrtle Beach, SC to Tampa, FL is by flight with an average journey time of 1h 42m.
Other travel options to Tampa, FL take longer:
Bus takes on average 12h 10m.
It's helpful to compare your options as there are 2 ways to travel between Myrtle Beach, SC and Tampa, FL including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Myrtle Beach, SC to Tampa, FL among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Myrtle Beach, SC to Tampa, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:55PM | Arrival Time 12:45PM | Duration 22h50 | Departure days Everyday | Cheapest price $114 |
Live departures
Myrtle Beach, SC to Tampa, FL bus times
The table below shows live departures for Myrtle Beach, SC to Tampa, FL buses for today, Wednesday, July 15. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 + FlixBus · FlixBus | 1:55 PM Myrtle Beach, N Oak St (Bus Station) | 23h20 | 1:15 PM Tampa, Marion Transit Center | 2 transfers | |
| +FlixBus · FlixBus | 1:55 PM Myrtle Beach, N Oak St (Bus Station) | 22h50 | 12:45 PM Tampa, USF Holly Drive (Central Plant), FL | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Myrtle Beach, SC to Tampa, FL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Myrtle Beach, SC to Tampa, FL buses with Omio?
FlixBus operates all buses services from Myrtle Beach, SC to Tampa, FL.
Omio is an official ticket reseller for all your travel options from Myrtle Beach, SC to Tampa, FL.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Myrtle Beach, SC to Tampa, FL.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Myrtle Beach, SC to Tampa, FL.
Journey information
Overview: Bus from Myrtle Beach, SC to Tampa, FL
USAUSA
Buses from Myrtle Beach, SC to Tampa, FL run on average 3 times per day, taking around 12h 10m. Cheap bus tickets for this journey start at $143 (€118) if you book in advance.
The earliest bus runs at 06:10, the last at 22:35. The fastest bus covers the 449 miles (724 km) distance in 19h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 449 miles (724 km) |
Average bus duration 12h 10m |
Cheapest ticket price $143 (€118) |
Buses per day 3 |
Fastest bus 19h 35m |
First bus 6:10 AM |
Last bus 10:35 PM |
Cheapest Month Sep |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Apr - Jun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus from Myrtle Beach, SC to Tampa, FLYou can travel by bus between Myrtle Beach, SC to Tampa, FL with FlixBus for as low as $143 (€118). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
19h 35m
Cheapest Price
$143 (€118)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Tampa
Things to do in Tampa
Discover the best of Tampa — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Tampa trip today.
- Must visit
Tampa Bay History Center
Engaging family-friendly museum exploring Tampa Bay history through exhibits on pirates, cigars, industry, and local communities.
- Recommended
Henry B. Plant Museum
Fascinating history museum inside the former Tampa Bay Hotel, showcasing Gilded Age rooms, décor, and Florida tourism heritage.
- Must visit
Tampa Riverwalk
Scenic waterfront promenade linking parks, museums, and downtown landmarks; ideal for walking, biking, and skyline views.
- Must visit
Ybor City
Tampa's most historic district, known for brick streets, cigar heritage, nightlife, and a distinctive Cuban and immigrant legacy.
- Must visit
Bayshore Boulevard
Popular bayside path and green space on Davis Islands with sweeping water views, downtown panoramas, and sunset appeal.
Tampa Cuban Sandwich
A Cuban sandwich layered with roast pork, ham, salami, Swiss cheese, pickles, and mustard on pressed Cuban bread. Tampa's version is a defining local classic.
Deviled Crab
Deviled crab is a Tampa staple: seasoned blue crab mixed with Cuban bread crumbs, shaped into a shell-like croquette, then breaded and fried.
- Vegetarian
- Gluten-free
Café Cubano
A chilled espresso drink sweetened and shaken until frothy. Popular in Tampa's Cuban communities, it is a local coffee ritual and social pick-me-up.
Brocato's Sandwich Shop
Beloved Tampa institution known for deviled crab, Cuban sandwiches, and casual old-Tampa counter service.
Rooster & The Till
Upscale modern Spanish restaurant in historic Ybor, known for refined tapas, cocktails, and a polished dining room.
Columbia Restaurant
Historic Ybor City restaurant famed for the original Tampa Cuban sandwich and old-school Spanish-Cuban atmosphere.
United States dollar ($)
Moderate for U.S. beach cities: hotels can be high in peak season, but dining and local transport are usually manageable for most visitors.
Average meal costs
- Budget
- $10-18 for fast food or casual takeout.
- Mid-range
- $20-40 per person for a meal.
- Fine dining
- $60+ per person for upscale restaurants.
- Coffee
- $3-6 for coffee or cappuccino.
Tipping culture
Tip 15-20% at restaurants, 18-22% for great service. Taxis usually 10-15%. For cafes, small change or $1 per drink is common but optional.
Transit
Get the appOfficial public transport app
Prices
- Single ticket
- $2.00
- Day pass
- $4.00
To the city center
Tampa International Airport -> Downtown Tampa, Tampa, FL
- Distance
- 9 km
- Travel time
- 20 min
- HART buses accept contactless payment and mobile ticketing through the Transit app; exact cash fare is also accepted on board.
- The HART day pass is usually best if you will take 2 or more bus trips in one day.
FAQs: Bus from Myrtle Beach, SC to Tampa, FL
Find answers to the most common questions about traveling from Myrtle Beach, SC to Tampa, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tampa, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Myrtle Beach, SC to Tampa, FL can start from as little as $143 (€118) when you book in advance. The average bus ticket price for Myrtle Beach, SC to Tampa, FL is $143 (€118) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Myrtle Beach, SC to Tampa, FL is 19h 35m to travel the 449 miles (724 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Myrtle Beach, SC to Tampa, FL leaves at 6:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Myrtle Beach, SC to Tampa, FL leaves at 10:35 PM.
There are 3 buses a day from Myrtle Beach, SC to Tampa, FL which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Myrtle Beach, SC to Tampa, FL, you can count on FlixBus for the best way to get you to Tampa, FL. You can also check all possible bus companies who offer a service between Myrtle Beach, SC and Tampa, FL and compare the amenities they offer before buying a bus ticket.
A trip to Tampa, FL from Myrtle Beach, SC is worth doing but not as a day trip with a journey time of 19h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Myrtle Beach, SC to Tampa, FL is September.
It's helpful to compare your options as there are 2 ways to travel between Myrtle Beach, SC and Tampa, FL including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Myrtle Beach, SC to Tampa, FL:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Myrtle Beach, SC to Tampa, FL for bus company FlixBus.
Some of the most interesting sights to explore in Tampa, FL are:
- Busch Gardens Tampa Bay, a renowned theme park offering thrilling rides and animal encounters
- The Florida Aquarium, a popular attraction featuring marine life exhibits and interactive experiences
- Tampa Riverwalk, a scenic waterfront path with parks, museums, and dining options
- Ybor City, a historic district known for its vibrant nightlife and Cuban culture
- Tampa Museum of Art, showcasing contemporary and classical art in a modern architectural setting.
The best things to do in Tampa, FL include:
- Visit the historic Henry B. Plant Museum, housed in a former luxury hotel with exhibits on the Gilded Age
- Explore the vibrant Hyde Park Village, offering shopping, dining, and entertainment
- Attend a Tampa Bay Buccaneers game at Raymond James Stadium for an exciting sports experience
- Take a boat tour of Tampa Bay for stunning views and wildlife sightings
- Enjoy a day at the beautiful Clearwater Beach, just a short drive from Tampa.
Whether you can cancel your bus ticket from Myrtle Beach, SC to Tampa, FL depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Myrtle Beach, SC to Tampa, FL.
Yes, the following luggage options are included when booking a bus ticket from Myrtle Beach, SC to Tampa, FL:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Myrtle Beach, SC to Tampa, FL:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Myrtle Beach, SC to Tampa, FL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Myrtle Beach, SC to Tampa, FL with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Myrtle Beach, SC to Tampa, FL with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Myrtle Beach, SC to Tampa, FL with the following bus company: FlixBus.
Since neither Myrtle Beach, SC nor Tampa, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Myrtle Beach, SC to Tampa, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Tampa, FL, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and popular tourist spots like Ybor City and downtown. Common scams include overcharging by taxi or rideshare drivers and timeshare presentations that pressure visitors into costly purchases. Staying aware of surroundings and using licensed transportation can help avoid these issues.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Myrtle Beach, SC to Tampa, FL
Most Myrtle Beach, SC to Tampa, FL buses use the Myrtle Beach, N Oak St (Bus Station) to Tampa, Marion Transit Center station pair, with some services arriving at Tampa, USF Holly Drive (Central Plant). Use this guide to compare Myrtle Beach, SC and Tampa, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Myrtle Beach
Arrival bus stations in Tampa
Myrtle Beach, N Oak St (Bus Station)
Tampa, Marion Transit Center
City-centre transport
Getting to Tampa, Marion Transit Center from Tampa city centre
Bus1, 5, 19, 30 · 3m · $5 · every ~15 min
Tampa, USF Holly Drive (Central Plant)
City-centre transport
Getting to Tampa, USF Holly Drive (Central Plant) from Tampa city centre
BusFlixBus 2421 · 26m · $1
9, 400 · 1h 3m · $5 · every ~7 min
6 · 1h 9m · $5 · every ~5 min
Most popular bus connections from Myrtle Beach, SC
More options for your journey from Myrtle Beach, SC to Tampa, FL
Here are some other resources that might have the information you need
Most popular buses to and from Tampa, FL and Myrtle Beach, SC
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