The cheapest and fastest buses from Myrtle Beach, SC to Tampa, FL
Cheapest price
$278
Average price
$278
Fastest journey
1 d 12 h 20 m
Average duration
1 d 12 h 20 m
Buses per day
1
Distance
724 km
The best way to find a cheap bus ticket from Myrtle Beach, SC to Tampa, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Myrtle Beach, SC to Tampa, FL will cost around $278 if you buy it on the day, but the cheapest tickets can be found for only $278.
It's difficult to get from Myrtle Beach, SC to Tampa, FL without transferring at least 2 times.


Travel Information
Compare bus and flight for Myrtle Beach, SC to Tampa, FL
Omio recommends booking the flight as it is the most popular option from Myrtle Beach, SC to Tampa, FL among Omio's users. If you are prioritising price take the bus with prices starting from €85. For those with little time consider booking a flight which can get you there in 3h 35m. The ticket price range depends on the travel mode: a bus costs an average of €85, and a flight costs an average of €68.
Distance: 449 miles (724 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
€107 Average price Cheapest | €162 Average price |
29h 55m Average total duration 29h 25m Onboard + 30m Additional time* | 6h 35m Average total duration Fastest 3h 35m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
Myrtle Beach, SC to Tampa, FL bus times
The table below shows live departures for Myrtle Beach, SC to Tampa, FL buses for today, Friday, November 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:45 PM Myrtle Beach, SC | 29h25 | 10:10 PM Tampa, FL | 0 transfersDirect | |
| Saturday, November 29 | |||||
![]() | 10:30 AM Myrtle Beach, SC | 36h20 | 10:50 PM Tampa, FL | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Myrtle Beach, SC to Tampa, FL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 29
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Journey information
Overview: Bus from Myrtle Beach, SC to Tampa, FL
Buses from Myrtle Beach, SC to Tampa, FL run on average 1 times per day, taking around 29h 25m. Cheap bus tickets for this journey start at $104 (€85) but you can travel from only $84 (€68) by flight.
The earliest bus runs at 11:10, the last at 12:45. The fastest bus covers the 449 miles (724 km) distance in 29h 25m.
Distance 449 miles (724 km) |
Average bus duration 29h 25m |
Cheapest ticket price $104 (€85) |
Buses per day 1 |
Fastest bus 29h 25m |
First bus 11:10 |
Last bus 12:45 |
Bus providers: Southeastern Stages from Myrtle Beach, SC to Tampa, FLYou can travel by bus between Myrtle Beach, SC to Tampa, FL with Southeastern Stages for as low as $84 (€68). When you search for schedules and tickets, Omio will show you the best journey
Southeastern Stages
FAQs: Bus from Myrtle Beach, SC to Tampa, FL
Find answers to the most common questions about traveling from Myrtle Beach, SC to Tampa, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Tampa, FL, this guide helps you travel smarter and with confidence.

- Busch Gardens Tampa Bay, a renowned theme park offering thrilling rides and animal encounters
- The Florida Aquarium, a popular attraction featuring marine life exhibits and interactive experiences
- Tampa Riverwalk, a scenic waterfront path with parks, museums, and dining options
- Ybor City, a historic district known for its vibrant nightlife and Cuban culture
- Tampa Museum of Art, showcasing contemporary and classical art in a modern architectural setting.
- Visit the historic Henry B. Plant Museum, housed in a former luxury hotel with exhibits on the Gilded Age
- Explore the vibrant Hyde Park Village, offering shopping, dining, and entertainment
- Attend a Tampa Bay Buccaneers game at Raymond James Stadium for an exciting sports experience
- Take a boat tour of Tampa Bay for stunning views and wildlife sightings
- Enjoy a day at the beautiful Clearwater Beach, just a short drive from Tampa.
To find the cheapest bus tickets for your trip from Myrtle Beach, SC to Tampa, FL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
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Popular bus stations from Myrtle Beach, SC to Tampa, FL
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