- Must visit
The Getty Center
Hilltop art museum with European paintings, sculpture, gardens, and striking architecture plus sweeping city views.
Omio recommends booking the bus as it is the most popular option from Myrtle Beach, SC to Los Angeles, CA among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $190 For those with little time, consider booking a flight, which has an average total journey time of 10h 37m. Average ticket prices depend on the travel mode: a bus costs an average of $190, while a flight costs an average of $221.
Distance: 2243 miles (3611 km)
Most popular Bus | Flight |
|---|---|
$190 Average price Cheapest | $221 Average price |
55h 50m Average total duration 55h 20m Onboard + 30m Additional time* | 10h 37m Average total duration Fastest 8h 37m Onboard + 2h 0m Additional time* |
Direct Options | Direct Options |
This is compared to other travel options from Myrtle Beach, SC to Los Angeles, CA:
A bus is $32 less than a flight for this route with tickets for a flight from Myrtle Beach, SC to Los Angeles, CA costing on average $221.
Other travel options to Los Angeles, CA take longer:
Bus takes on average 55h 20m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 11:50AM | Arrival Time 10:10PM | Duration 85h20 | Departure days Thu, Fri | Cheapest price $199 |
Operator Greyhound | Departure Time 12:40PM | Arrival Time 10:30PM | Duration 60h50 | Departure days Thu, Fri | Cheapest price $201 |
Operator Greyhound | Departure Time 12:45PM | Arrival Time 04:45AM | Duration 67h00 | Departure days Thu, Fri | Cheapest price $210 |
Operator Greyhound USA | Departure Time 01:55PM | Arrival Time 05:10AM | Duration 63h15 | Departure days Wed | Cheapest price $731 |
Operator Greyhound | Departure Time 06:55PM | Arrival Time 06:30AM | Duration 59h35 | Departure days Sat | Cheapest price $665 |
The table below shows live departures for Myrtle Beach, SC to Los Angeles, CA buses for today, Saturday, September 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:55 PM Myrtle Beach, SC | 59h35 | 6:30 AM Los Angeles, CA | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Myrtle Beach, SC to Los Angeles, CA run on average 2 times per day, taking around 55h 20m. Cheap bus tickets for this journey start at $176 but you can travel from only $144 by flight.
The earliest bus runs at 09:35, the last at 23:30. The fastest bus covers the 2243 miles (3611 km) distance in 59h 35m.
Distance 2243 miles (3611 km) |
Average bus duration 55h 20m |
Cheapest ticket price $176 |
Buses per day 2 |
Fastest bus 59h 35m |
First bus 9:35 AM |
Last bus 11:30 PM |
Cheapest Month Aug |
Cheapest Day Sun |
Discover the best of Los Angeles, CA — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Los Angeles, CA trip today.
Hilltop art museum with European paintings, sculpture, gardens, and striking architecture plus sweeping city views.
Major contemporary art museum in Downtown LA, known for broad collections, special shows, and bold architecture.
World-class encyclopedic museum on Wilshire Boulevard, famous for diverse collections and the Urban Light installation.
Legendary boulevard known for the Walk of Fame, theaters, neon, and classic Hollywood atmosphere mixed with tourist energy.
Lively beachside promenade with street performers, Muscle Beach, and easy access to the Venice Boardwalk scene.
Major urban park with trails, the observatory, picnic areas, and some of the best public views in Los Angeles.
A bacon-wrapped hot dog grilled on a street cart and topped with peppers, onions, mustard, ketchup, and mayo. A late-night Los Angeles street food classic.
A French dip sandwich of thin-sliced roast beef on a roll, often dipped in meat jus. Los Angeles claims the original and locals still debate the best version.
Double corn tortillas filled with stewed beef, birria broth, onions, and cilantro. A beloved Los Angeles Mexican staple, especially popular from trucks and taquerias.
Acclaimed fine-dining restaurant serving a seasonal California tasting menu. Refined, intimate, and one of Los Angeles's most respected special-occasion venues.
Legendary taqueria known for charcoal-grilled carne asada tacos. Casual, fast-paced, and widely considered one of Los Angeles's essential taco stops.
Historic downtown deli linked to the French dip. Old-school counter service and classic sandwiches in a landmark Los Angeles setting.
Los Angeles is pricier than many U.S. cities for hotels, dining, parking, and rides. Budget options exist, but tourist areas and transport costs raise daily spend.
Tip 18-20% in restaurants, 15-20% for taxis or rideshares, and $1-2 at cafes for counter service or coffee.
Find answers to the most common questions about traveling from Myrtle Beach, SC to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

Most Myrtle Beach, SC to Los Angeles, CA buses use the Myrtle Beach, N Oak St (Bus Station) to Los Angeles, Cesar E Chavez / Vignes station pair, with some services arriving at Los Angeles, Patsaouras Transit Plaza (Union Station). Use this guide to compare Myrtle Beach, SC and Los Angeles, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Myrtle Beach, N Oak St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Myrtle Beach, N Oak St (Bus Station). ATMs are available at Myrtle Beach, N Oak St (Bus Station).
Ticket office support is available at Myrtle Beach, N Oak St (Bus Station).
Available at Myrtle Beach, N Oak St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Myrtle Beach, N Oak St (Bus Station): Wheelchair accessible entry available.
Los Angeles, Cesar E Chavez / Vignes is 1 km from Los Angeles city centre. Public transport options include:
Los Angeles, Cesar E Chavez / Vignes has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Los Angeles, Cesar E Chavez / Vignes. ATMs are available at Los Angeles, Cesar E Chavez / Vignes.
Ticket office support is available at Los Angeles, Cesar E Chavez / Vignes.
Available at Los Angeles, Cesar E Chavez / Vignes: Parking, Taxis, WC.
Accessibility facilities are available at Los Angeles, Cesar E Chavez / Vignes: The station is accessible to people with disabilities.
Los Angeles, Patsaouras Transit Plaza (Union Station) is 1 km from Los Angeles city centre. Public transport options include:
Los Angeles, Patsaouras Transit Plaza (Union Station) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Food court and various dining options available.
Wi-Fi available in main waiting areas. ATMs are aTMs available near main concourse.
Ticket office support is available at Los Angeles, Patsaouras Transit Plaza (Union Station).
Available at Los Angeles, Patsaouras Transit Plaza (Union Station): Parking, Taxis, WC.
Accessibility facilities are available at Los Angeles, Patsaouras Transit Plaza (Union Station): Station fully accessible with elevators and ramps.
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