The cheapest and fastest buses from Milwaukee, WI to La Crosse, WI
Cheapest price
$65
Average price
$65
Fastest journey
3 h 40 m
Average duration
3 h 40 m
Buses per day
1
Distance
282 km
The best way to find a cheap bus ticket from Milwaukee, WI to La Crosse, WI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milwaukee, WI to La Crosse, WI will cost around $65 if you buy it on the day, but the cheapest tickets can be found for only $65.
Of the 1 buses that leave Milwaukee, WI for La Crosse, WI on Tue, May 19, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, May 19 the direct buses cover the 282 km distance in an average of 3 h 40 m but if you time it right, some buses will get you there in just 3 h 40 m .
On Tue, May 19 the slowest buses will take 3 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:50 PM3h40Milwaukee, WI5:30 PMLa Crosse, WI$651One-way0 transfers
1:50 PM3h40Milwaukee, WI5:30 PMLa Crosse, WI$651One-way0 transfers
Travel Information
Compare train and bus for Milwaukee, WI to La Crosse, WI
Omio recommends booking the train as it is the most popular option from Milwaukee, WI to La Crosse, WI among Omio's users. If you are prioritising price take the bus with prices starting from $56. For those with little time consider booking a train which can get you there in 3h 19m. The ticket price range depends on the travel mode: a bus costs an average of $56, and a train costs an average of $26.
Distance: 175 miles (282 km)
Compare bus with
| Bus | Most popular Train | Driving |
|---|---|---|
$62 Average price Cheapest | $81 Average price | $44 Average price (fuel + tolls) |
4h 45m Average total duration 4h 15m Onboard + 30m Additional time* | 3h 49m Average total duration Fastest 3h 19m Onboard + 30m Additional time* | 3h 42m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Milwaukee, WI to La Crosse, WI:
A bus is $19 (€15) less than a train for this route with tickets for a train from Milwaukee, WI to La Crosse, WI costing on average $81 (€65).
Other travel options to La Crosse, WI take longer:
Bus takes on average 4h 15m.
You'll arrive about -1h -33m sooner (4h 15m by bus vs 3h 42m by car) and save roughly $-17.95 (€-14.51) compared to fuel and tolls ($62 (€50) vs $44 (€35)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Jefferson Lines.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Milwaukee, WI to La Crosse, WI Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Infobus | Departure Time 01:50PM | Arrival Time 05:30PM | Duration 3h40 | Departure days Everyday | Cheapest price $56 |
Operator Infobus | Departure Time 03:00PM | Arrival Time 06:40PM | Duration 3h40 | Departure days Sun | Cheapest price $58 |
Live departures
Milwaukee, WI to La Crosse, WI bus times
The table below shows live departures for Milwaukee, WI to La Crosse, WI buses for today, Monday, May 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:50 PM Milwaukee, WI | 3h40 | 5:30 PM La Crosse, WI | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milwaukee, WI to La Crosse, WI by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 19
May 20
May 21
May 22
May 23
May 24
May 25
Why should you book Milwaukee, WI to La Crosse, WI buses with Omio?
Why book with Omio vs Infobus?
- Compare with other providers: On Omio, you can not only buy tickets for Infobus, but also compare tickets for the likes of Jefferson Lines to find the best option for your trip from Milwaukee, WI to La Crosse, WI.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Infobus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Milwaukee, WI to La Crosse, WI.
Why book with Omio over Busbud or Checkmybus?
- Official reseller: Infobus tickets can only be bought on Omio or Infobus's website as Omio is the only official third party seller for Infobus tickets. Busbud or Checkmybus do not sell Infobus tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Milwaukee, WI to La Crosse, WI.
Journey information
Overview: Bus from Milwaukee, WI to La Crosse, WI
Buses from Milwaukee, WI to La Crosse, WI run on average 2 times per day, taking around 4h 15m. Cheap bus tickets for this journey start at $56 (€46) but you can travel from only $26 (€21) by train.
There are 2 buses per day. The earliest bus runs at 08:50, the last at 16:10. The fastest bus covers the 175 miles (282 km) distance in 3h 40m.
Distance 175 miles (282 km) |
Average bus duration 4h 15m |
Cheapest ticket price $56 (€46) |
Buses per day 2 |
Direct buses 2 |
Fastest bus 3h 40m |
First bus 8:50 AM |
Last bus 4:10 PM |
Cheapest Month Feb |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Wed |
Best time to book 14 days |
Bus providers: Infobus, Jefferson Lines from Milwaukee, WI to La Crosse, WIYou can travel by bus between Milwaukee, WI to La Crosse, WI with Infobus, Jefferson Lines for as low as $26 (€21). When you search for schedules and tickets, Omio will show you the best journey
Infobus
Jefferson Lines
FAQs: Bus from Milwaukee, WI to La Crosse, WI
Find answers to the most common questions about traveling from Milwaukee, WI to La Crosse, WI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at La Crosse, WI, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- Infobus
- 10€ per additional bag.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
popular bus stations
Popular bus stations from Milwaukee, WI to La Crosse, WI
Most popular bus connections from Milwaukee, WI
More options for your journey from Milwaukee, WI to La Crosse, WI
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