The cheapest and fastest buses from South San Francisco, CA to Los Angeles, CA
Cheapest price
$58
Average price
$59
Fastest journey
11 h 11 m
Average duration
12 h 20 m
Buses per day
5
Distance
549 km
The best way to find a cheap bus ticket from South San Francisco, CA to Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from South San Francisco, CA to Los Angeles, CA will cost around $59 if you buy it on the day, but the cheapest tickets can be found for only $58.
Of the 5 buses that leave South San Francisco, CA for Los Angeles, CA on Mon, May 04, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, May 04 the direct buses cover the 549 km distance in an average of 12 h 20 m but if you time it right, some buses will get you there in just 11 h 11 m .
On Mon, May 04 the slowest buses will take 15 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
3:50 PM11h29South San Francisco, CA3:19 AMLos Angeles, CA$581One-way0 transfers
3:45 PM11h58South San Francisco, CA3:43 AMLos Angeles, CA$581One-way0 transfers
12:00 AM15h30South San Francisco, CA3:30 PMLos Angeles, CA$581One-way0 transfers
6:35 AM11h11South San Francisco, CA5:46 PMLos Angeles, CA$591One-way0 transfers
1:15 PM11h33South San Francisco, CA12:48 AMLos Angeles, CA$601One-way0 transfers
6:35 AM11h11South San Francisco, CA5:46 PMLos Angeles, CA$591One-way0 transfers
3:50 PM11h29South San Francisco, CA3:19 AMLos Angeles, CA$581One-way0 transfers
1:15 PM11h33South San Francisco, CA12:48 AMLos Angeles, CA$601One-way0 transfers
3:45 PM11h58South San Francisco, CA3:43 AMLos Angeles, CA$581One-way0 transfers
12:00 AM15h30South San Francisco, CA3:30 PMLos Angeles, CA$581One-way0 transfers
Travel Information
Compare bus, train, and flight for South San Francisco, CA to Los Angeles, CA
Omio recommends booking the train as it is the most popular option from South San Francisco, CA to Los Angeles, CA among Omio's users. If you are prioritising price take the bus with prices starting from $40. For those with little time consider booking a flight which can get you there in 1h 38m. The ticket price range depends on the travel mode: a bus costs an average of $40, and a flight costs an average of $63.
Distance: 341 miles (549 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$61 Average price Cheapest | $97 Average price | $145 Average price |
12h 47m Average total duration 12h 17m Onboard + 30m Additional time* | 11h 37m Average total duration 11h 7m Onboard + 30m Additional time* | 4h 38m Average total duration Fastest 1h 38m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
South San Francisco, CA to Los Angeles, CA bus times
The table below shows live departures for South San Francisco, CA to Los Angeles, CA buses for today, Sunday, May 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:30 PM South San Francisco, CA | 13h25 | 3:55 AM Los Angeles, CA | 0 transfersDirect | |
![]() | 3:45 PM South San Francisco, CA | 11h58 | 3:43 AM Los Angeles, CA | 0 transfersDirect | |
![]() | 3:50 PM South San Francisco, CA | 11h54 | 3:44 AM Los Angeles, CA | 0 transfersDirect | |
| Monday, May 4 | |||||
![]() | 12:00 AM South San Francisco, CA | 15h30 | 3:30 PM Los Angeles, CA | 0 transfersDirect | |
![]() | 6:35 AM South San Francisco, CA | 11h11 | 5:46 PM Los Angeles, CA | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets South San Francisco, CA to Los Angeles, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 04
May 05
May 06
May 07
May 08
May 09
May 10
Journey information
Overview: Bus from South San Francisco, CA to Los Angeles, CA
Buses from South San Francisco, CA to Los Angeles, CA run on average 25 times per day, taking around 12h 17m. Cheap bus tickets for this journey start at $40 (€32) if you book in advance.
There are 4 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 341 miles (549 km) distance in 9h 15m.
Distance 341 miles (549 km) |
Average bus duration 12h 17m |
Cheapest ticket price $40 (€32) |
Buses per day 25 |
Direct buses 4 |
Fastest bus 9h 15m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Mon |
Least Busy Day Mon |
FAQs: Bus from South San Francisco, CA to Los Angeles, CA
Find answers to the most common questions about traveling from South San Francisco, CA to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.

- Griffith Observatory, an iconic facility offering stunning views of Los Angeles and exhibits on astronomy
- The Getty Center, a renowned art museum with impressive architecture and beautiful gardens
- Santa Monica Pier, a historic landmark featuring an amusement park, aquarium, and scenic ocean views
- Hollywood Walk of Fame, a famous sidewalk celebrating entertainment industry icons with star plaques
- Los Angeles County Museum of Art (LACMA), the largest art museum in the western United States with diverse collections.
- Explore the vibrant Venice Beach Boardwalk, known for its eclectic shops, street performers, and skate park
- Visit the historic El Capitan Theatre for a classic movie experience
- Take a scenic hike in Runyon Canyon Park, offering panoramic views of the city
- Enjoy a live performance at the Walt Disney Concert Hall, known for its stunning architecture and acoustics
- Discover the unique exhibits at the Natural History Museum of Los Angeles County.
popular bus stations
Popular bus stations from South San Francisco, CA to Los Angeles, CA
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