- Must visit
The Getty Center
Major hilltop art museum with European paintings, decorative arts, architecture, and city views; one of Los Angeles’s signature cultural sites.
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The cheapest and fastest buses from South San Francisco, CA to Los Angeles, CA
Showing times and prices for Jun 19
Cheapest price
$51
Average price
$82
Fastest journey
7 h 35 m
Average duration
10 h 23 m
Buses per day
8
Distance
549 km
Cheap tickets
The best way to find a cheap bus ticket from South San Francisco, CA to Los Angeles, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from South San Francisco, CA to Los Angeles, CA will cost around $82 if you buy it on the day, but the cheapest tickets can be found for only $51.
Fast buses
Of the 8 buses that leave South San Francisco, CA for Los Angeles, CA on Fri, Jun 19, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 19 the direct buses cover the 549 km distance in an average of 10 h 23 m but if you time it right, some buses will get you there in just 7 h 35 m .
On Fri, Jun 19 the slowest buses will take 11 h 58 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
11:00 PM15h30South San Francisco, CA2:30 PMLos Angeles, CA$511One-way0 transfers- 2:30 PM13h25South San Francisco, CA3:55 AMLos Angeles, CA$541One-way0 transfers
- 5:40 AM9h15South San Francisco, CA2:55 PMLos Angeles, CA$541One-way0 transfers
3:45 PM11h58South San Francisco, CA3:43 AMLos Angeles, CA$571One-way0 transfers- 2:45 PM11h58South San Francisco, CA2:43 AMLos Angeles, CA$591One-way0 transfers
6:25 AM7h35South San Francisco, CA2:00 PMLos Angeles, CA$1301One-way0 transfers- 5:40 AM9h15South San Francisco, CA2:55 PMLos Angeles, CA$541One-way0 transfers
- 5:35 AM11h11South San Francisco, CA4:46 PMLos Angeles, CA$591One-way0 transfers
- 3:45 PM11h58South San Francisco, CA3:43 AMLos Angeles, CA$571One-way0 transfers
- 2:45 PM11h58South San Francisco, CA2:43 AMLos Angeles, CA$591One-way0 transfers
Travel Information
Compare bus, train, and flight for South San Francisco, CA to Los Angeles, CA
Omio recommends booking the bus as it is the most popular option from South San Francisco, CA to Los Angeles, CA among Omio's users. If you are prioritising price take the bus with prices starting from $37. For those with little time consider booking a flight which can get you there in 1h 35m. The ticket price range depends on the travel mode: a bus costs an average of $37, and a flight costs an average of $62.
Distance: 341 miles (549 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$59 Average price Cheapest | $94 Average price | $153 Average price | $77 Average price (fuel + tolls) |
9h 3m Average total duration 8h 33m Onboard + 30m Additional time* | 11h 27m Average total duration 10h 57m Onboard + 30m Additional time* | 4h 35m Average total duration Fastest 1h 35m Onboard + 3h 0m Additional time* | 5h 44m Average total duration (door-to-door) |
Most popular bus company | Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from South San Francisco, CA to Los Angeles, CA is a bus with an average price of $59 (€48).
This is compared to other travel options from South San Francisco, CA to Los Angeles, CA:
A bus is $35 (€29) less than a train for this route with tickets for a train from South San Francisco, CA to Los Angeles, CA costing on average $94 (€77).
A bus is $94 (€77) less than a flight for this route with tickets for a flight from South San Francisco, CA to Los Angeles, CA costing on average $153 (€125).
The fastest way to travel from South San Francisco, CA to Los Angeles, CA is by flight with an average journey time of 1h 35m.
Other travel options to Los Angeles, CA take longer:
Bus takes on average 8h 33m.
Train takes on average 10h 57m.
It's helpful to compare your options as there are 3 ways to travel between South San Francisco, CA and Los Angeles, CA including taking a bus, train, and flight.
We recommend using the bus as it is the most popular way to get from South San Francisco, CA to Los Angeles, CA among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
South San Francisco, CA to Los Angeles, CA Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:00AM | Arrival Time 03:30PM | Duration 15h30 | Departure days Fri, Sat | Cheapest price $45 |
Operator Amtrak | Departure Time 05:35AM | Arrival Time 04:46PM | Duration 11h11 | Departure days Wed, Sat | Cheapest price $58 |
Operator Greyhound | Departure Time 05:40AM | Arrival Time 02:55PM | Duration 9h15 | Departure days Mon, Wed, Fri, Sat | Cheapest price $44 |
Operator FlixBus | Departure Time 06:25AM | Arrival Time 02:00PM | Duration 7h35 | Departure days Wed, Sat | Cheapest price $55 |
Operator Amtrak | Departure Time 06:35AM | Arrival Time 05:46PM | Duration 11h11 | Departure days Thu | Cheapest price $58 |
Operator Greyhound | Departure Time 06:40AM | Arrival Time 03:55PM | Duration 9h15 | Departure days Thu, Sun | Cheapest price $48 |
Operator Greyhound | Departure Time 01:30PM | Arrival Time 02:55AM | Duration 13h25 | Departure days Mon, Wed, Sun | Cheapest price $40 |
Operator Greyhound | Departure Time 02:30PM | Arrival Time 03:55AM | Duration 13h25 | Departure days Mon, Fri, Sun | Cheapest price $52 |
Operator Amtrak | Departure Time 02:45PM | Arrival Time 02:43AM | Duration 11h58 | Departure days Everyday | Cheapest price $57 |
Operator Amtrak | Departure Time 03:45PM | Arrival Time 03:43AM | Duration 11h58 | Departure days Everyday | Cheapest price $57 |
Operator Amtrak | Departure Time 03:50PM | Arrival Time 03:19AM | Duration 11h29 | Departure days Tue | Cheapest price $57 |
Operator Greyhound | Departure Time 07:40PM | Arrival Time 05:10AM | Duration 9h30 | Departure days Mon, Thu | Cheapest price $51 |
Operator Greyhound | Departure Time 08:40PM | Arrival Time 06:10AM | Duration 9h30 | Departure days Sat | Cheapest price $68 |
Operator Greyhound | Departure Time 11:00PM | Arrival Time 02:30PM | Duration 15h30 | Departure days Mon, Tue, Fri, Sun | Cheapest price $37 |
Live departures
South San Francisco, CA to Los Angeles, CA bus times
The table below shows live departures for South San Francisco, CA to Los Angeles, CA buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 5:40 AM South San Francisco, CA | 9h15 | 2:55 PM Los Angeles, CA | 0 transfersDirect | |
| 2:45 PM South San Francisco, CA | 11h58 | 2:43 AM Los Angeles, CA | 0 transfersDirect | |
| 3:45 PM South San Francisco, CA | 11h58 | 3:43 AM Los Angeles, CA | 0 transfersDirect | |
| 7:40 PM South San Francisco, CA | 9h30 | 5:10 AM Los Angeles, CA | 0 transfersDirect | |
| Friday, June 19 | |||||
| 12:00 AM South San Francisco, CA | 15h30 | 3:30 PM Los Angeles, CA | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets South San Francisco, CA to Los Angeles, CA by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Jun 19
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Jun 25
Why should you book South San Francisco, CA to Los Angeles, CA buses with Omio?
Greyhound as well as FlixBus offer buses services from South San Francisco, CA to Los Angeles, CA.
Omio is an official ticket reseller for all your travel options from South San Francisco, CA to Los Angeles, CA.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from South San Francisco, CA to Los Angeles, CA.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from South San Francisco, CA to Los Angeles, CA.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from South San Francisco, CA to Los Angeles, CA.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from South San Francisco, CA to Los Angeles, CA.
Journey information
Overview: Bus from South San Francisco, CA to Los Angeles, CA
USAUSA
Buses from South San Francisco, CA to Los Angeles, CA run on average 21 times per day, taking around 8h 33m. Cheap bus tickets for this journey start at $37 (€30) if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 341 miles (549 km) distance in 7h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 341 miles (549 km) |
Average bus duration 8h 33m |
Cheapest ticket price $37 (€30) |
Buses per day 21 |
Direct buses 3 |
Fastest bus 7h 35m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Mon |
Least Busy Day Mon |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus from South San Francisco, CA to Los Angeles, CAYou can travel by bus between South San Francisco, CA to Los Angeles, CA with Greyhound, FlixBus for as low as $37 (€30). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
7h 35m
Cheapest Price
$47 (€38)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
9h 15m
Cheapest Price
$37 (€30)
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Los Angeles
Things to do in Los Angeles
Discover the best of Los Angeles — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Los Angeles trip today.
- Must visit
Los Angeles County Museum of Art (LACMA)
The largest art museum in the western United States, known for broad global collections and the iconic Urban Light installation.
- Must visit
The Broad
Popular contemporary art museum in Downtown Los Angeles with works by Kusama, Warhol, and other major postwar artists.
- Must visit
Griffith Park
Vast urban park with trails, scenic overlooks, and access to major attractions; a classic Los Angeles outdoor destination.
- Must visit
Santa Monica Pier
Iconic oceanfront boardwalk area with classic California views and broad appeal for first-time visitors.
- Must visit
Venice Beach Boardwalk
Famous beachfront promenade known for street culture, skate scenes, murals, and constant people-watching.
French Dip Sandwich
A Los Angeles classic of thinly sliced roast beef on a roll, served with rich jus for dipping. It is one of the city’s most iconic old-school sandwiches.
- Gluten-free
L.A.-Style Tacos
Street tacos are central to Los Angeles food culture, especially carne asada, al pastor, and grilled fish tacos served on corn tortillas with salsa, onion, and cilantro.
Korean Barbecue
A signature Los Angeles meal shaped by Koreatown, featuring grilled marinated meats, banchan, and shared dining. The city is especially known for its strong Korean barbecue scene.
Providence
Acclaimed fine dining restaurant known for refined seafood tasting menus and elegant service. One of Los Angeles’s top special-occasion destinations.
Philippe The Original
Historic downtown institution famous for the French dip sandwich. Casual, old-school atmosphere and one of Los Angeles’s most iconic food stops.
Guelaguetza
Well-known Oaxacan restaurant celebrated for complex moles, tlayudas, and mezcal. Lively atmosphere and a landmark for regional Mexican cuisine in Los Angeles.
United States Dollar
Los Angeles is expensive for visitors. Hotels, parking, and dining add up quickly, though casual food and some neighborhoods offer better value.
Average meal costs
- Budget
- USD 10-18 for fast food or casual takeout.
- Mid-range
- USD 25-45 per person at a mid-range restaurant.
- Fine dining
- USD 80+ per person before drinks and tip.
- Coffee
- USD 4-7 for a regular coffee or latte.
Tipping culture
Tip 18-20% at restaurants; 20%+ for great service. Bars: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 2-5. Not expected at fast-food spots.
FAQs: Bus from South San Francisco, CA to Los Angeles, CA
Find answers to the most common questions about traveling from South San Francisco, CA to Los Angeles, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Los Angeles, CA, this guide helps you travel smarter and with confidence.
Cheap bus tickets from South San Francisco, CA to Los Angeles, CA can start from as little as $37 (€30) when you book in advance. The average bus ticket price for South San Francisco, CA to Los Angeles, CA is $59 (€48) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from South San Francisco, CA to Los Angeles, CA is 7h 35m to travel the 341 miles (549 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from South San Francisco, CA to Los Angeles, CA leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from South San Francisco, CA to Los Angeles, CA leaves at 11:55 PM.
Yes, there are 3 direct buses a day from South San Francisco, CA to Los Angeles, CA with . Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from South San Francisco, CA to Los Angeles, CA, you can count on Greyhound, FlixBus for the best way to get you to Los Angeles, CA. You can also check all possible bus companies who offer a service between South San Francisco, CA and Los Angeles, CA and compare the amenities they offer before buying a bus ticket.
A trip to Los Angeles, CA from South San Francisco, CA is worth doing but not as a day trip with a journey time of 7h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from South San Francisco, CA to Los Angeles, CA is March.
It's helpful to compare your options as there are 3 ways to travel between South San Francisco, CA and Los Angeles, CA including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from South San Francisco, CA to Los Angeles, CA:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from South San Francisco, CA to Los Angeles, CA for bus company Greyhound, FlixBus.
Some of the most interesting sights to explore in Los Angeles, CA are:
- Griffith Observatory, an iconic facility offering stunning views of Los Angeles and exhibits on astronomy
- The Getty Center, a renowned art museum with impressive architecture and beautiful gardens
- Santa Monica Pier, a historic landmark featuring an amusement park, aquarium, and scenic ocean views
- Hollywood Walk of Fame, a famous sidewalk celebrating entertainment industry icons with star plaques
- Los Angeles County Museum of Art (LACMA), the largest art museum in the western United States with diverse collections.
The best things to do in Los Angeles, CA include:
- Explore the vibrant Venice Beach Boardwalk, known for its eclectic shops, street performers, and skate park
- Visit the historic El Capitan Theatre for a classic movie experience
- Take a scenic hike in Runyon Canyon Park, offering panoramic views of the city
- Enjoy a live performance at the Walt Disney Concert Hall, known for its stunning architecture and acoustics
- Discover the unique exhibits at the Natural History Museum of Los Angeles County.
Whether you can cancel your bus ticket from South San Francisco, CA to Los Angeles, CA depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from South San Francisco, CA to Los Angeles, CA.
Yes, the following luggage options are included when booking a bus ticket from South San Francisco, CA to Los Angeles, CA:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from South San Francisco, CA to Los Angeles, CA:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from South San Francisco, CA to Los Angeles, CA. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from South San Francisco, CA to Los Angeles, CA with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from South San Francisco, CA to Los Angeles, CA with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from South San Francisco, CA to Los Angeles, CA with the following bus company: Greyhound, FlixBus.
Since neither South San Francisco, CA nor Los Angeles, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from South San Francisco, CA to Los Angeles, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Los Angeles, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded or tourist-heavy areas like Hollywood and Venice Beach. Common scams include fake ticket vendors near popular attractions and overcharging by unlicensed ride services. It's important to use official transportation options, stay aware of surroundings, and avoid sharing personal information with strangers to stay safe.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from South San Francisco, CA to Los Angeles, CA
Most South San Francisco, CA to Los Angeles, CA buses use the San Francisco, Transit Center Bay 29 to Los Angeles, Patsaouras Transit Plaza (Union Station) station pair, with some services arriving at Los Angeles, Gayley / Strathmore. Use this guide to compare South San Francisco, CA and Los Angeles, CA bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in South San Francisco
Arrival bus stations in Los Angeles
Los Angeles, Patsaouras Transit Plaza (Union Station)
City-centre transport
Getting to Los Angeles, Patsaouras Transit Plaza (Union Station) from Los Angeles city centre
Bus4X · 8m · $2
SubwayMetro B Line, Metro D Line · 12m · $2 · every ~24 min
Los Angeles, Gayley / Strathmore
City-centre transport
Getting to Los Angeles, Gayley / Strathmore from Los Angeles city centre
BusFlixBus N2002, FlixBus N2030, FlixBus 2000 · 25m · $2
431B, 431 · 41m · $5
20 · 1h 4m · $2 · every ~3 min
20 · 1h 32m · $2 · every ~8 min
Los Angeles, Cesar E Chavez / Vignes
City-centre transport
Getting to Los Angeles, Cesar E Chavez / Vignes from Los Angeles city centre
Bus40, 74 · 3m · $2 · every ~15 min
33 · 4m · $2 · every ~9 min
D · 11m · $5 · every ~12 min
490, 495, 499, 699, 493, 498, 707 · 13m · $7 · every ~9 min
TramMetro A Line · 10m · $2 · every ~12 min
SubwayMetro B Line, Metro D Line · 10m · $2 · every ~24 min
More options for your journey from South San Francisco, CA to Los Angeles, CA
Here are some other resources that might have the information you need
Most popular buses to and from Los Angeles, CA and South San Francisco, CA
Most popular bus connections to Los Angeles, CA
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