4.9
4.6The cheapest and fastest buses from Chicago, IL to Jefferson City, MO
Cheapest price on Sep 15
$69
Average ticket price on Sep 15
$69
Fastest journey on Sep 15
16 h 50 m
Average journey duration on Sep 15
17 h
Buses on Sep 15
2
Distance
529 km
The best way to find a cheap bus ticket from Chicago, IL to Jefferson City, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Chicago, IL to Jefferson City, MO will cost around $69 if you buy it on the day, but the cheapest tickets can be found for only $69.
It's difficult to get from Chicago, IL to Jefferson City, MO without transferring at least 2 times.
· · 11:10 PM16h50Chicago, Union Station (Amtrak), IL4:00 PMJefferson City, Eastland Dr (Greyhound Bus Station), MO$691One-way2 transfers- · · 10:50 PM17h10Chicago, Greyhound Bus Station4:00 PMJefferson City, Eastland Dr (Greyhound Bus Station), MO$691One-way2 transfers
- · · 11:10 PM16h50Chicago, Union Station (Amtrak), IL4:00 PMJefferson City, Eastland Dr (Greyhound Bus Station), MO$691One-way2 transfers
- · · 10:50 PM17h10Chicago, Greyhound Bus Station4:00 PMJefferson City, Eastland Dr (Greyhound Bus Station), MO$691One-way2 transfers
Travel Information
Compare train, bus, and flight for Chicago, IL to Jefferson City, MO
Omio recommends booking the train as it is the most popular option from Chicago, IL to Jefferson City, MO among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $106 For those with little time, consider booking a flight, which has an average total journey time of 6h 44m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of $106, while a flight costs an average of $669.
Distance: 328 miles (529 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$106 Average price Cheapest | $106 Average price | $669 Average price | $81 Average price (fuel + tolls) |
12h 6m Average total duration 11h 36m Onboard + 30m Additional time* | 7h 59m Average total duration 7h 29m Onboard + 30m Additional time* | 6h 44m Average total duration Fastest 4h 44m Onboard + 2h 0m Additional time* | 5h 59m Average total duration (door-to-door) |
0.5 - 1.3kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Chicago, IL to Jefferson City, MO:
A bus is $0.06 (€0.05) less than a train for this route with tickets for a train from Chicago, IL to Jefferson City, MO costing on average $106 (€87).
A bus is $562 (€457) less than a flight for this route with tickets for a flight from Chicago, IL to Jefferson City, MO costing on average $669 (€544).
Other travel options to Jefferson City, MO take longer:
Train takes on average 7h 29m.
Bus takes on average 11h 36m.
Tickets start at around $106 (€87) compared to roughly $81 (€66) in fuel and tolls — a saving of about $-25.01 (€-20.35). The journey takes 11h 36m versus 5h 59m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Chicago, IL to Jefferson City, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:15AM | Arrival Time 04:00PM | Duration 15h45 | Departure days Mon, Thu, Sat | Cheapest price $58 |
Operator Greyhound | Departure Time 05:10AM | Arrival Time 10:00PM | Duration 16h50 | Departure days Thu | Cheapest price $110 |
Operator FlixBus | Departure Time 05:15AM | Arrival Time 09:00PM | Duration 15h45 | Departure days Wed, Fri, Sun | Cheapest price $71 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 10:00PM | Duration 15h45 | Departure days Sun | Cheapest price $61 |
Operator Greyhound | Departure Time 10:50PM | Arrival Time 04:00PM | Duration 17h10 | Departure days Mon, Tue, Thu, Sat | Cheapest price $69 |
Operator Greyhound | Departure Time 11:10PM | Arrival Time 04:00PM | Duration 16h50 | Departure days Mon, Tue, Thu, Sat | Cheapest price $69 |
Live departures
Chicago, IL to Jefferson City, MO bus times
The table below shows live departures for Chicago, IL to Jefferson City, MO buses for today, Monday, September 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| · · | 10:50 PM Chicago, Greyhound Bus Station | 17h10 | 4:00 PM Jefferson City, Eastland Dr (Greyhound Bus Station), MO | 2 transfers | |
| · · | 11:10 PM Chicago, Union Station (Amtrak), IL | 16h50 | 4:00 PM Jefferson City, Eastland Dr (Greyhound Bus Station), MO | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Chicago, IL to Jefferson City, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 15
Sep 16
Sep 17
Sep 18
Sep 19
Sep 20
Sep 21
Journey information
Overview: Bus from Chicago, IL to Jefferson City, MO
USAUSA
Buses from Chicago, IL to Jefferson City, MO run on average 3 times per day, taking around 11h 36m. Cheap bus tickets for this journey start at $58 (€47) if you book in advance.
The earliest bus runs at 00:15, the last at 23:45. The fastest bus covers the 328 miles (529 km) distance in 10h 10m.
Distance 328 miles (529 km) |
Average bus duration 11h 36m |
Cheapest ticket price $58 (€47) |
Buses per day 3 |
Fastest bus 10h 10m |
First bus 12:15 AM |
Last bus 11:45 PM |
Cheapest Month Sep |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Mon |
Least Busy Day Mon |
Best time to book 35 days |
FAQs: Bus from Chicago, IL to Jefferson City, MO
Find answers to the most common questions about traveling from Chicago, IL to Jefferson City, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jefferson City, MO, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from Chicago, IL to Jefferson City, MO
Most Chicago, IL to Jefferson City, MO buses use the Chicago, Greyhound Bus Station to Jefferson City, Eastland Dr (Greyhound Bus Station) station pair. Use this guide to compare Chicago, IL and Jefferson City, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Chicago, IL station do buses to Jefferson City, MO leave from?
Getting to Chicago, Greyhound Bus Station from Chicago city centre
Chicago, Greyhound Bus Station is 2 km from Chicago city centre. Public transport options include:
Chicago, Greyhound Bus Station bus station facilities and services
Chicago, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Snack shop and vending machines available
Wi-Fi and ATMs
Free Wi-Fi in waiting area. ATMs are located near entrance.
Tickets and information
Ticket office support is available at Chicago, Greyhound Bus Station.
Parking, taxis and toilets
Available at Chicago, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Greyhound Bus Station: Wheelchair accessible entrances and seating.
Getting to Chicago, 95th Red Line Station from Chicago city centre
Chicago, 95th Red Line Station is 14 km from Chicago city centre. Public transport options include:
Chicago, 95th Red Line Station bus station facilities and services
Chicago, 95th Red Line Station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Chicago, 95th Red Line Station. ATMs are available at Chicago, 95th Red Line Station.
Tickets and information
Ticket office support is available at Chicago, 95th Red Line Station.
Parking, taxis and toilets
Available at Chicago, 95th Red Line Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, 95th Red Line Station: Wheelchair accessible entrances available.
Getting to Chicago, Union Station (Amtrak) from Chicago city centre
Chicago, Union Station (Amtrak) is 3 km from Chicago city centre. Public transport options include:
Chicago, Union Station (Amtrak) bus station facilities and services
Chicago, Union Station (Amtrak) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Multiple dining options are available inside the station.
Wi-Fi and ATMs
Free Wi-Fi is available in waiting areas. ATMs are aTMs are located near the main entrance.
Tickets and information
Ticket office support is available at Chicago, Union Station (Amtrak).
Parking, taxis and toilets
Available at Chicago, Union Station (Amtrak): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Chicago, Union Station (Amtrak): Station is accessible with elevators and ramps.
Which Jefferson City, MO station do buses from Chicago, IL arrive at?
Getting to Jefferson City, Eastland Dr (Greyhound Bus Station) from Jefferson City city centre
Jefferson City, Eastland Dr (Greyhound Bus Station) is 3 km from Jefferson City city centre. Public transport options include:
Jefferson City, Eastland Dr (Greyhound Bus Station) bus station facilities and services
Jefferson City, Eastland Dr (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Jefferson City, Eastland Dr (Greyhound Bus Station). ATMs are available at Jefferson City, Eastland Dr (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Jefferson City, Eastland Dr (Greyhound Bus Station).
Parking, taxis and toilets
Available at Jefferson City, Eastland Dr (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Jefferson City, Eastland Dr (Greyhound Bus Station): Wheelchair ramps are available.
Most popular bus connections from Chicago, IL
More options for your journey from Chicago, IL to Jefferson City, MO
Here are some other resources that might have the information you need
Most popular buses to and from Jefferson City, MO and Chicago, IL
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