4.9
4.6The cheapest and fastest buses from Chicago, IL to Jefferson City, MO
Cheapest price
$62
Average price
$67
Fastest journey
15 h 45 m
Average duration
15 h 45 m
Buses per day
2
Distance
529 km
The best way to find a cheap bus ticket from Chicago, IL to Jefferson City, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Chicago, IL to Jefferson City, MO will cost around $67 if you buy it on the day, but the cheapest tickets can be found for only $62.
Of the 2 buses that leave Chicago, IL for Jefferson City, MO on Sun, May 31, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, May 31 the direct buses cover the 529 km distance in an average of 15 h 45 m but if you time it right, some buses will get you there in just 15 h 45 m .
On Sun, May 31 the slowest buses will take 15 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
6:15 AM15h45Chicago, IL10:00 PMJefferson City, MO$621One-way0 transfers- 5:15 AM15h45Chicago, IL9:00 PMJefferson City, MO$721One-way0 transfers
- 6:15 AM15h45Chicago, IL10:00 PMJefferson City, MO$621One-way0 transfers
- 5:15 AM15h45Chicago, IL9:00 PMJefferson City, MO$721One-way0 transfers
Travel Information
Compare train, bus, and flight for Chicago, IL to Jefferson City, MO
Omio recommends booking the train as it is the most popular option from Chicago, IL to Jefferson City, MO among Omio's users. If you are prioritising price take the train with prices starting from $53. For those with little time consider booking a flight which can get you there in 1h 35m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a train costs an average of $53, and a flight costs an average of $155.
Distance: 328 miles (529 km)
Compare bus with
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$124 Average price | $93 Average price Cheapest | $303 Average price | $81 Average price (fuel + tolls) |
16h 45m Average total duration 16h 15m Onboard + 30m Additional time* | 8h 15m Average total duration 7h 45m Onboard + 30m Additional time* | 4h 35m Average total duration Fastest 1h 35m Onboard + 3h 0m Additional time* | 5h 59m Average total duration (door-to-door) |
0.5 - 1.3kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Chicago, IL to Jefferson City, MO:
A train is $30 (€24) less than a bus for this route with tickets for a bus from Chicago, IL to Jefferson City, MO costing on average $124 (€99).
A train is $209 (€168) less than a flight for this route with tickets for a flight from Chicago, IL to Jefferson City, MO costing on average $303 (€244).
Other travel options to Jefferson City, MO take longer:
Train takes on average 7h 45m.
Bus takes on average 16h 15m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Chicago, IL to Jefferson City, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:15AM | Arrival Time 04:00PM | Duration 15h45 | Departure days Thu, Sat | Cheapest price $74 |
Operator Greyhound | Departure Time 03:50AM | Arrival Time 09:00PM | Duration 17h10 | Departure days Tue, Wed | Cheapest price $98 |
Operator Greyhound | Departure Time 05:10AM | Arrival Time 10:00PM | Duration 16h50 | Departure days Thu | Cheapest price $111 |
Operator FlixBus | Departure Time 05:15AM | Arrival Time 09:00PM | Duration 15h45 | Departure days Mon, Tue, Wed, Fri, Sun | Cheapest price $72 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 10:00PM | Duration 15h45 | Departure days Mon, Sun | Cheapest price $62 |
Operator Greyhound | Departure Time 10:50PM | Arrival Time 04:00PM | Duration 17h10 | Departure days Thu, Sat | Cheapest price $78 |
Operator Greyhound | Departure Time 11:10PM | Arrival Time 04:00PM | Duration 16h50 | Departure days Thu, Sat | Cheapest price $78 |
Live departures
Chicago, IL to Jefferson City, MO bus times
The table below shows live departures for Chicago, IL to Jefferson City, MO buses for today, Saturday, May 30. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 · · | 10:50 PM Chicago, Greyhound Bus Station | 17h10 | 4:00 PM Jefferson City, Eastland Dr (Greyhound Bus Station), MO | 2 transfers | |
| · · | 11:10 PM Chicago, Union Station (Amtrak), IL | 16h50 | 4:00 PM Jefferson City, Eastland Dr (Greyhound Bus Station), MO | 2 transfers | |
| Sunday, May 31 | |||||
| 5:15 AM Chicago, IL | 15h45 | 9:00 PM Jefferson City, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Chicago, IL to Jefferson City, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 31
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Jun 02
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Jun 06
Journey information
Overview: Bus from Chicago, IL to Jefferson City, MO
USAUSA
Buses from Chicago, IL to Jefferson City, MO run on average 4 times per day, taking around 16h 15m. Cheap bus tickets for this journey start at $62 (€50) but you can travel from only $53 (€43) by train.
The earliest bus runs at 00:15, the last at 23:45. The fastest bus covers the 328 miles (529 km) distance in 14h 45m.
Distance 328 miles (529 km) |
Average bus duration 16h 15m |
Cheapest ticket price $62 (€50) |
Buses per day 4 |
Fastest bus 14h 45m |
First bus 12:15 AM |
Last bus 11:45 PM |
Cheapest Month Sep |
Cheapest Day Fri |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Thu |
Least Busy Day Tue |
Best time to book 28 days |
FAQs: Bus from Chicago, IL to Jefferson City, MO
Find answers to the most common questions about traveling from Chicago, IL to Jefferson City, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jefferson City, MO, this guide helps you travel smarter and with confidence.
popular bus stations
Popular bus stations from Chicago, IL to Jefferson City, MO
Most popular bus connections from Chicago, IL
More options for your journey from Chicago, IL to Jefferson City, MO
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Most popular buses to and from Jefferson City, MO and Chicago, IL
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