- Must visit
Delaware Art Museum
Leading Delaware art museum with American illustration, Pre-Raphaelite works, sculpture gardens, and a scenic setting above Brandywine Creek.
Omio recommends booking the bus as it is the most popular option from Harrisburg, PA to Wilmington, NC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $134 For those with little time, consider booking a bus, which has an average total journey time of 15h 14m. Average ticket prices depend on the travel mode: a bus costs an average of $134, while a bus costs an average of $134.
Distance: 421 miles (679 km)
| Train | Most popular Bus | Driving |
|---|---|---|
$134 Average price Cheapest | $97 Average price (fuel + tolls) | |
15h 14m Average total duration Fastest 14h 44m Onboard + 30m Additional time* | 7h 40m Average total duration (door-to-door) | |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Harrisburg, PA to Wilmington, NC:
A bus is $506 (€413) less than a flight for this route with tickets for a flight from Harrisburg, PA to Wilmington, NC costing on average $639 (€523).
Other travel options to Wilmington, NC take longer:
Bus takes on average 14h 44m.
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a train from Harrisburg, PA to Wilmington, NC and enjoy the approximately 421 miles (679 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 05:00, the last at 10:20.
Distance 421 miles (679 km) |
First train 5:00 AM |
Last train 10:20 AM |
Cheapest Month May |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Discover the best of Wilmington, NC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Wilmington, NC trip today.
Leading Delaware art museum with American illustration, Pre-Raphaelite works, sculpture gardens, and a scenic setting above Brandywine Creek.
Historic prison turned museum interpreting crime, punishment, and justice in Delaware through preserved cells and guided tours.
Hands-on children's museum on the Riverfront with interactive science, math, and creativity exhibits designed for families and younger visitors.
Redeveloped waterfront district with river walks, parks, public art, and easy access to museums, dining, and seasonal events.
Major civic square framed by historic buildings, offices, and hotels, often used for public events and a good starting point downtown.
Large urban park with formal gardens, open lawns, trails, sports areas, and frequent community events near downtown neighborhoods.
Find answers to the most common questions about traveling from Harrisburg, PA to Wilmington, NC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Wilmington, NC, this guide helps you travel smarter and with confidence.

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