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Journey information
Overview: Bus from Harrisburg, PA to Myrtle Beach, SC
Take a bus from Harrisburg, PA to Myrtle Beach, SC and enjoy the approximately 467 miles (753 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 12:45, the last at 12:55.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 467 miles (753 km) |
Buses per day 1 |
First bus 12:45 |
Last bus 12:55 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
FAQs: Bus from Harrisburg, PA to Myrtle Beach, SC
Find answers to the most common questions about traveling from Harrisburg, PA to Myrtle Beach, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Myrtle Beach, SC, this guide helps you travel smarter and with confidence.

Cheap bus tickets from Harrisburg, PA to Myrtle Beach, SC can start from as little as $160 (€131) when you book in advance. The average bus ticket price for Harrisburg, PA to Myrtle Beach, SC is $203 (€166); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Harrisburg, PA to Myrtle Beach, SC bus time is 26 h 40 min covering the 467 mile (753 km) long route, but the journey time can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Harrisburg, PA to Myrtle Beach, SC leaves at 12: 50PM. Plan your trip with the Journey Planner from Omio.
The last bus from Harrisburg, PA to Myrtle Beach, SC leaves at 2: 30PM.
The cheapest month to travel from Harrisburg, PA to Myrtle Beach, SC by bus is October.
Yes, you can take a bus between Harrisburg, PA and Myrtle Beach, SC.
No, the bus from Harrisburg, PA to Myrtle Beach, SC has no accessibility options.
No, there are no bathrooms on board the bus from Harrisburg, PA to Myrtle Beach, SC.
No, bikes are not allowed on board the bus from Harrisburg, PA to Myrtle Beach, SC.
To find the cheapest bus tickets for your trip from Harrisburg, PA to Myrtle Beach, SC, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from Harrisburg, PA to Myrtle Beach, SC.
No, luggage for the bus from Harrisburg, PA to Myrtle Beach, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Harrisburg, PA to Myrtle Beach, SC.
Unfortunately, pets are not allowed on the bus from Harrisburg, PA to Myrtle Beach, SC.
No, there are no USB plugs on board the bus from Harrisburg, PA to Myrtle Beach, SC.
No, there is no WiFi on board the bus from Harrisburg, PA to Myrtle Beach, SC.
popular bus stations
Popular bus stations from Harrisburg, PA to Myrtle Beach, SC
Harrisburg
Myrtle Beach
The major bus station for departures in Harrisburg is Harrisburg, Market St (Bus Station). Find all the information you need to know about services, amenities and connections at Harrisburg, Market St (Bus Station) for your trip from Harrisburg to Myrtle Beach.
Harrisburg, Market St (Bus Station)
information
Harrisburg, Chestnut Street / South 4th Street
information
The major bus station for arrivals in Myrtle Beach is Myrtle Beach, N Oak St (Bus Station). Find all the information you need to know about services, amenities and connections at Myrtle Beach, N Oak St (Bus Station) for your trip to Myrtle Beach from Harrisburg.
Myrtle Beach, N Oak St (Bus Station)
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Most popular bus connections from Harrisburg, PA
More options for your journey from Harrisburg, PA to Myrtle Beach, SC
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