Harrisburg, PA to Myrtle Beach, SC bus with Greyhound

Fri, Mar 20
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2,000+ travel companies
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The cheapest and fastest buses from Harrisburg, PA to Myrtle Beach, SC

Showing times and prices for Mar 22

Cheapest price

$161

Average price

$161

Fastest journey

1 d 4 h 40 m

Average duration

1 d 4 h 40 m

Buses per day

1

Distance

753 km

Cheap tickets

The best way to find a cheap bus ticket from Harrisburg, PA to Myrtle Beach, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Harrisburg, PA to Myrtle Beach, SC will cost around $161 if you buy it on the day, but the cheapest tickets can be found for only $161.

Fast buses

It's difficult to get from Harrisburg, PA to Myrtle Beach, SC without transferring at least 3 times.

Greyhound USA
12:30PM28h40
Harrisburg, PA
05:10PMMyrtle Beach, SC
$1611One-way
3 transfers

Live departures

Harrisburg, PA to Myrtle Beach, SC bus times

The table below shows live departures for Harrisburg, PA to Myrtle Beach, SC buses for today, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.

Last updated at 1:23 AM
ProviderDepartsDurationArrivesTransfers
Tickets
greyhound12:30 PM Harrisburg, PA
28h40
5:10 PM Myrtle Beach, SC3 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Harrisburg, PA to Myrtle Beach, SC by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Mar 22
Mon
Mar 23
Tue
Mar 24
Wed
Mar 25
Thu
Mar 26
Fri
Mar 27
Sat
Mar 28

Why should you book Harrisburg, PA to Myrtle Beach, SC buses with Omio?

Greyhound operates all buses services from Harrisburg, PA to Myrtle Beach, SC.
Omio is an official ticket reseller for all your travel options from Harrisburg, PA to Myrtle Beach, SC.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Journey information

Overview: Bus from Harrisburg, PA to Myrtle Beach, SC

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Icon of bus

Buses from Harrisburg, PA to Myrtle Beach, SC run on average 1 times per day, taking around 25h 7m. Cheap bus tickets for this journey start at $254 (€206) if you book in advance.

The earliest bus runs at 12:45, the last at 13:55. The fastest bus covers the 467 miles (753 km) distance in 25h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
467 miles (753 km)
Average bus duration
25h 7m
Cheapest ticket price
$254 (€206)
Buses per day
1
Fastest bus
25h 0m
First bus
12:45
Last bus
13:55
Cheapest month
Mar
Cheapest day
Sun
High season
Oct - Dec
Low season
Jan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Harrisburg, PA to Myrtle Beach, SCYou can travel by bus between Harrisburg, PA to Myrtle Beach, SC with Greyhound for as low as $254 (€206). When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
25h 0m
Cheapest Price
$254 (€206)
Greyhound frequency
1 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Harrisburg, PA to Myrtle Beach, SC

Find answers to the most common questions about traveling from Harrisburg, PA to Myrtle Beach, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Myrtle Beach, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Harrisburg, PA to Myrtle Beach, SC can start from as little as $254 (€206) when you book in advance. The average bus ticket price for Harrisburg, PA to Myrtle Beach, SC is $323 (€262) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Harrisburg, PA to Myrtle Beach, SC is 25h 0m to travel the 467 miles (753 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Harrisburg, PA to Myrtle Beach, SC leaves at 12:45 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from Harrisburg, PA to Myrtle Beach, SC leaves at 1:55 PM.
There are 1 buses a day from Harrisburg, PA to Myrtle Beach, SC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Harrisburg, PA to Myrtle Beach, SC, you can count on Greyhound for the best way to get you to Myrtle Beach, SC. You can also check all possible bus companies who offer a service between Harrisburg, PA and Myrtle Beach, SC and compare the amenities they offer before buying a bus ticket.
A trip to Myrtle Beach, SC from Harrisburg, PA is worth doing but not as a day trip with a journey time of 25h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Harrisburg, PA to Myrtle Beach, SC is March.
Yes, you can take a bus between Harrisburg, PA and Myrtle Beach, SC.
Yes, the following accessibility options are available when taking the bus from Harrisburg, PA to Myrtle Beach, SC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Harrisburg, PA to Myrtle Beach, SC for bus company Greyhound.
Whether you can cancel your bus ticket from Harrisburg, PA to Myrtle Beach, SC depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Harrisburg, PA to Myrtle Beach, SC.
Yes, the following luggage options are included when booking a bus ticket from Harrisburg, PA to Myrtle Beach, SC:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Harrisburg, PA to Myrtle Beach, SC:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Harrisburg, PA to Myrtle Beach, SC.
You can reserve your seat on the bus from Harrisburg, PA to Myrtle Beach, SC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Harrisburg, PA to Myrtle Beach, SC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Harrisburg, PA to Myrtle Beach, SC with the following bus company: Greyhound.

popular bus stations

Popular bus stations from Harrisburg, PA to Myrtle Beach, SC

Harrisburg
Myrtle Beach
The major bus station for departures in Harrisburg is Harrisburg, Market St (Bus Station). Find all the information you need to know about services, amenities and connections at Harrisburg, Market St (Bus Station) for your trip from Harrisburg to Myrtle Beach.
Harrisburg, Market St (Bus Station)
information
Harrisburg, Chestnut Street / South 4th Street
information

More options for your journey from Harrisburg, PA to Myrtle Beach, SC

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Tickets and more information for coaches to Harrisburg, PA
Tickets and more information for coaches to Myrtle Beach, SC

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HomeBusesBuses in USABus tickets to Myrtle Beach, SCHarrisburg, PA to Myrtle Beach, SC bus

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