Harrisburg, PA to Myrtle Beach, SC bus with Greyhound

Sat, Sep 19
+ Add return
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
Greyhound
FlixBus
Alsa
BlaBlaCar Bus
Rede Expressos
2,000+ travel companies
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

The cheapest and fastest buses from Harrisburg, PA to Myrtle Beach, SC

Showing times, prices and bookable tickets for Sep 19

Cheapest price on Sep 19

$103

Average ticket price on Sep 19

$108

Fastest journey on Sep 19

22 h 20 m

Average journey duration on Sep 19

23 h 33 m

Buses on Sep 19

2

Distance

753 km

Cheap tickets

The best way to find a cheap bus ticket from Harrisburg, PA to Myrtle Beach, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Harrisburg, PA to Myrtle Beach, SC will cost around $108 if you buy it on the day, but the cheapest tickets can be found for only $103.

Fast buses

It's difficult to get from Harrisburg, PA to Myrtle Beach, SC without transferring at least 3 times.

  • Greyhound+FlixBusFlixBus+Greyhound ·
    11:30 PM24h45
    Harrisburg, Market St (Bus Station), PA
    12:15 AMMyrtle Beach, N Oak St (Bus Station)
    $1031One-way
    3 transfers
  • FlixBusFlixBus+Greyhound · ·
    5:30 PM22h20
    Harrisburg, Market St (Bus Station), PA
    3:50 PMMyrtle Beach, N Oak St (Bus Station)
    $1121One-way
    4 transfers

Travel Information

Compare bus for Harrisburg, PA to Myrtle Beach, SC

Omio recommends booking the bus as it is the most popular option from Harrisburg, PA to Myrtle Beach, SC among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $135 For those with little time, consider booking a bus, which has an average total journey time of 19h 11m. Average ticket prices depend on the travel mode: a bus costs an average of $135, while a bus costs an average of $135.

Distance: 467 miles (753 km)

Compare bus with

Most popular
Bus
Driving

$135

Average price

Cheapest

$109

Average price

(fuel + tolls)

19h 11m

Average total duration

Fastest

18h 41m

Onboard

+

30m

Additional time*

9h 1m

Average total duration

(door-to-door)

Greyhound

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

The cheapest way to travel from Harrisburg, PA to Myrtle Beach, SC is a bus with an average price of $135.
The fastest way to travel from Harrisburg, PA to Myrtle Beach, SC is by bus with an average journey time of 18h 41m.
Yes, you can take a bus between Harrisburg, PA and Myrtle Beach, SC.
We recommend using the bus as it is the most popular way to get from Harrisburg, PA to Myrtle Beach, SC among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $135 compared to roughly $109 in fuel and tolls — a saving of about $-26.08. The journey takes 18h 41m versus 9h 1m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Harrisburg, PA to Myrtle Beach, SC Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
03:55PM
Arrival Time
03:50PM
Duration
23h55
Departure days
Wed, Thu
Cheapest price
$86
Operator
Greyhound
Departure Time
05:30PM
Arrival Time
03:50PM
Duration
22h20
Departure days
Mon, Tue, Fri, Sat, Sun
Cheapest price
$87
Operator
Greyhound
Departure Time
11:30PM
Arrival Time
12:15AM
Duration
24h45
Departure days
Everyday
Cheapest price
$85

Live departures

Harrisburg, PA to Myrtle Beach, SC bus times

The table below shows live departures for Harrisburg, PA to Myrtle Beach, SC buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus+Greyhound · · 5:30 PM Harrisburg, Market St (Bus Station), PA
22h20
3:50 PM Myrtle Beach, N Oak St (Bus Station)4 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Harrisburg, PA to Myrtle Beach, SC by bus

Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sat
Sep 19
Sun
Sep 20
Mon
Sep 21
Tue
Sep 22
Wed
Sep 23
Thu
Sep 24
Fri
Sep 25

Why should you book Harrisburg, PA to Myrtle Beach, SC buses with Omio?

Greyhound operates all buses services from Harrisburg, PA to Myrtle Beach, SC.
Omio is an official ticket reseller for all your travel options from Harrisburg, PA to Myrtle Beach, SC.

Why book with Omio vs Greyhound?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.

Journey information

Overview: Bus from Harrisburg, PA to Myrtle Beach, SC

USAUSA
USAUSA
Icon of bus

Buses from Harrisburg, PA to Myrtle Beach, SC run on average 2 times per day, taking around 18h 41m. Cheap bus tickets for this journey start at $89 if you book in advance.

The earliest bus runs at 12:45, the last at 13:55. The fastest bus covers the 467 miles (753 km) distance in 14h 45m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
467 miles (753 km)
Average bus duration
18h 41m
Cheapest ticket price
$89
Buses per day
2
Fastest bus
14h 45m
First bus
12:45 PM
Last bus
1:55 PM
Cheapest Month
Jun
Cheapest Day
Fri
High Season
Jul - Sep
Low Season
Oct - Dec
Best time to book
28 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound from Harrisburg, PA to Myrtle Beach, SCYou can travel by bus between Harrisburg, PA to Myrtle Beach, SC with Greyhound for as low as $89. When you search for schedules and tickets, Omio will show you the best journey

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
14h 45m
Cheapest Greyhound Price
$89
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Harrisburg, PA to Myrtle Beach, SC

Find answers to the most common questions about traveling from Harrisburg, PA to Myrtle Beach, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Myrtle Beach, SC, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Harrisburg, PA to Myrtle Beach, SC can start from as little as $89 when you book in advance. The average bus ticket price for Harrisburg, PA to Myrtle Beach, SC is $135 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Harrisburg, PA to Myrtle Beach, SC is 14h 45m to travel the 467 miles (753 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Harrisburg, PA to Myrtle Beach, SC leaves at 12:45 PM. Plan your trip with the Journey Planner from Omio.
The latest bus from Harrisburg, PA to Myrtle Beach, SC leaves at 1:55 PM.
There are 2 buses a day from Harrisburg, PA to Myrtle Beach, SC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Harrisburg, PA to Myrtle Beach, SC, you can count on Greyhound for the best way to get you to Myrtle Beach, SC. You can also check all possible bus companies who offer a service between Harrisburg, PA and Myrtle Beach, SC and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Harrisburg, Market St (Bus Station), PA, which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Myrtle Beach, N Oak St (Bus Station), located 0 away from the city centre.
A trip to Myrtle Beach, SC from Harrisburg, PA is worth doing but not as a day trip with a journey time of 14h 45m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Harrisburg, PA to Myrtle Beach, SC is June.
Yes, you can take a bus between Harrisburg, PA and Myrtle Beach, SC.
Yes, the following accessibility options are available when taking the bus from Harrisburg, PA to Myrtle Beach, SC:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Harrisburg, PA to Myrtle Beach, SC for bus company Greyhound.
Whether you can cancel your bus ticket from Harrisburg, PA to Myrtle Beach, SC depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Harrisburg, PA to Myrtle Beach, SC.
Yes, the following luggage options are included when booking a bus ticket from Harrisburg, PA to Myrtle Beach, SC:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Harrisburg, PA to Myrtle Beach, SC:
  • Greyhound
    • $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Harrisburg, PA to Myrtle Beach, SC.
You can reserve your seat on the bus from Harrisburg, PA to Myrtle Beach, SC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Harrisburg, PA to Myrtle Beach, SC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Harrisburg, PA to Myrtle Beach, SC with the following bus company: Greyhound.
Since neither Harrisburg, PA nor Myrtle Beach, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Harrisburg, PA to Myrtle Beach, SC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Myrtle Beach, SC, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like the boardwalk and beaches. Common scams include overcharging by taxi drivers and unofficial tour operators. It's advisable to use licensed transportation services and be wary of unsolicited offers. Additionally, travelers should stay aware of their surroundings at night and secure personal belongings to ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Harrisburg, PA to Myrtle Beach, SC

Most Harrisburg, PA to Myrtle Beach, SC buses use the Harrisburg, Market St (Bus Station) to Myrtle Beach, N Oak St (Bus Station) station pair. Use this guide to compare Harrisburg, PA and Myrtle Beach, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Harrisburg
Arrival bus stations in Myrtle Beach

Which Harrisburg, PA station do buses to Myrtle Beach, SC leave from?

Buses from Harrisburg, PA to Myrtle Beach, SC leave from Harrisburg, Market St (Bus Station). The station is 0 miles (1 km) from Harrisburg, PA city centre at Harrisburg, 411 Market St, Harrisburg, PA 17101, USA.
Harrisburg, Market St (Bus Station)Harrisburg, 411 Market St, Harrisburg, PA 17101, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Harrisburg, Market St (Bus Station) from Harrisburg city centre

Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:

Bus6/13, W · 29m · $4 · every ~4 min

Harrisburg, Market St (Bus Station) bus station facilities and services

Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).

Tickets and information

Ticket office support is available at Harrisburg, Market St (Bus Station).

Parking, taxis and toilets

Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.

More options for your journey from Harrisburg, PA to Myrtle Beach, SC

Here are some other resources that might have the information you need

HomeBusesBuses in USABus tickets to Myrtle Beach, SCHarrisburg, PA to Myrtle Beach, SC bus

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone