- Recommended
The Franklin G. Burroughs-Simeon B. Chapin Art Museum
Compact museum sharing regional military history through uniforms, weapons, artifacts, and exhibits on local veterans and conflicts.
The best way to find a cheap bus ticket from Syracuse, NY to Myrtle Beach, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse, NY to Myrtle Beach, SC will cost around $342 if you buy it on the day, but the cheapest tickets can be found for only $342.
On Wed, Nov 04, we found 1 buses from Syracuse, NY to Myrtle Beach, SC, including 1 direct services.
On Wed, Nov 04 the direct buses cover the 1068 km distance in an average of 1 d 50 m but if you time it right, some buses will get you there in just 1 d 50 m .
On Wed, Nov 04 the slowest buses will take 1 d 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

|
| ||||||||||||

|
| ||||||||||||
Buses from Syracuse, NY to Myrtle Beach, SC run on average 2 times per day, taking around 22h 39m. Cheap bus tickets for this journey start at $79 if you book in advance.
The earliest bus runs at 12:45, the last at 15:00. The fastest bus covers the 663 miles (1068 km) distance in 18h 25m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Syracuse, NY to Myrtle Beach, SC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 02:00PM | Arrival Time 03:50PM | Duration 25h50 | Departure days Tue, Thu, Sun | Cheapest price $109 |
Operator FlixBus | Departure Time 03:45PM | Arrival Time 08:50PM | Duration 29h05 | Departure days Mon | Cheapest price $196 |
Operator Greyhound | Departure Time 07:00PM | Arrival Time 07:50PM | Duration 24h50 | Departure days Mon, Wed, Fri, Sat | Cheapest price $179 |
Operator Greyhound | Departure Time 07:20PM | Arrival Time 12:15AM | Duration 28h55 | Departure days Tue, Thu, Sun | Cheapest price $103 |
Operator Greyhound | Departure Time 08:00PM | Arrival Time 08:50PM | Duration 24h50 | Departure days Fri, Sat | Cheapest price $155 |
The table below shows live departures for Syracuse, NY to Myrtle Beach, SC buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · · | 2:00 PM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 25h50 | 3:50 PM Myrtle Beach, N Oak St (Bus Station) | 3 transfers | |
· · | 7:20 PM Syracuse, Walsh Cir (Syracuse Bus Station), NY | 28h55 | 12:15 AM Myrtle Beach, N Oak St (Bus Station) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Syracuse, NY to Myrtle Beach, SC with Greyhound. Overnight buses available on this route with Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Myrtle Beach, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Myrtle Beach, SC trip today.
Compact museum sharing regional military history through uniforms, weapons, artifacts, and exhibits on local veterans and conflicts.
Beachfront art museum with rotating exhibitions, community programs, and regional works in a former oceanfront residence.
Hands-on science museum for families with interactive exhibits on space, physics, and natural science at Broadway at the Beach.
Popular entertainment district around a lake with wide walking paths, shops, attractions, and evening activity close to the beach.
Oceanfront district combining the boardwalk, beach access, entertainment, and public spaces for an easy first visit to the city.
Upscale shopping and walking area with landscaped streets, boutiques, lakefront paths, and seasonal events in a relaxed setting.
Lowcountry boil with shrimp, sausage, corn, and potatoes, seasoned and boiled together. A Carolina coast staple popular at beach gatherings and seafood feasts.
She-crab soup is a rich coastal soup made with crab meat, crab roe, cream, and sherry. It is a classic South Carolina specialty served along the Grand Strand.
Shrimp and grits pairs local shrimp with creamy grits, often with bacon or gravy. It is one of the most iconic dishes in South Carolina coastal cooking.
Casual local favorite for Southern breakfast and brunch, especially shrimp and grits, biscuits, and hearty comfort food.
Upscale seafood restaurant known for refined Lowcountry dishes, steaks, and a polished dining room near the ocean.
Lively, long-running waterfront spot on the MarshWalk serving fresh local seafood, sushi, and regional favorites in a casual setting.
Moderate for a US beach city: hotels rise in peak season, dining is mid-priced, and car-based travel adds parking and fuel costs.
Tip 18-20% at restaurants, more for excellent service. Taxis usually 10-15%. Small tips are optional at cafes.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Myrtle Beach, SC.
Find answers to the most common questions about traveling from Syracuse, NY to Myrtle Beach, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Myrtle Beach, SC, this guide helps you travel smarter and with confidence.

Most Syracuse, NY to Myrtle Beach, SC buses use the Syracuse, Walsh Cir (Syracuse Bus Station) to Myrtle Beach, N Oak St (Bus Station) station pair. Use this guide to compare Syracuse, NY and Myrtle Beach, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Syracuse, Walsh Cir (Syracuse Bus Station) is 3 km from Syracuse city centre. Public transport options include:
Syracuse, Walsh Cir (Syracuse Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available throughout the station. ATMs are aTMs are located near the entrance.
Ticket office support is available at Syracuse, Walsh Cir (Syracuse Bus Station).
Available at Syracuse, Walsh Cir (Syracuse Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Syracuse, Walsh Cir (Syracuse Bus Station): The station is wheelchair accessible.
Myrtle Beach, N Oak St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Myrtle Beach, N Oak St (Bus Station). ATMs are available at Myrtle Beach, N Oak St (Bus Station).
Ticket office support is available at Myrtle Beach, N Oak St (Bus Station).
Available at Myrtle Beach, N Oak St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Myrtle Beach, N Oak St (Bus Station): Wheelchair accessible entry available.
Check bus stations information for Syracuse, NY and Myrtle Beach, SC, including where buses depart and arrive on this route.