The cheapest and fastest buses from Syracuse, NY to Myrtle Beach, SC
Cheapest price
$253
Average price
$253
Fastest journey
1 d 50 m
Average duration
1 d 50 m
Buses per day
1
Distance
1068 km
The best way to find a cheap bus ticket from Syracuse, NY to Myrtle Beach, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Syracuse, NY to Myrtle Beach, SC will cost around $253 if you buy it on the day, but the cheapest tickets can be found for only $253.
Of the 1 buses that leave Syracuse, NY for Myrtle Beach, SC on Sun, Mar 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 22 the direct buses cover the 1068 km distance in an average of 1 d 50 m but if you time it right, some buses will get you there in just 1 d 50 m .
On Sun, Mar 22 the slowest buses will take 1 d 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and flight for Syracuse, NY to Myrtle Beach, SC
Omio recommends booking the bus as it is the most popular option from Syracuse, NY to Myrtle Beach, SC among Omio's users. If you are prioritising price take the bus with prices starting from $142. For those with little time consider booking a flight which can get you there in 14h 13m. The ticket price range depends on the travel mode: a bus costs an average of $142, and a flight costs an average of $551.
Distance: 663 miles (1068 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
$207 Average price Cheapest | $556 Average price |
24h 55m Average total duration 24h 25m Onboard + 30m Additional time* | 17h 13m Average total duration Fastest 14h 13m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
Syracuse, NY to Myrtle Beach, SC bus times
The table below shows live departures for Syracuse, NY to Myrtle Beach, SC buses for today, Saturday, March 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:00 PM Syracuse, NY | 24h50 | 8:50 PM Myrtle Beach, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Syracuse, NY to Myrtle Beach, SC by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book Syracuse, NY to Myrtle Beach, SC buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Syracuse, NY to Myrtle Beach, SC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Syracuse, NY to Myrtle Beach, SC.
Journey information
Overview: Bus from Syracuse, NY to Myrtle Beach, SC
Buses from Syracuse, NY to Myrtle Beach, SC run on average 1 times per day, taking around 24h 25m. Cheap bus tickets for this journey start at $142 (€115) if you book in advance.
The earliest bus runs at 12:45, the last at 13:55. The fastest bus covers the 663 miles (1068 km) distance in 24h 50m.
Distance 663 miles (1068 km) |
Average bus duration 24h 25m |
Cheapest ticket price $142 (€115) |
Buses per day 1 |
Fastest bus 24h 50m |
First bus 12:45 |
Last bus 13:55 |
Bus providers: Greyhound from Syracuse, NY to Myrtle Beach, SCYou can travel by bus between Syracuse, NY to Myrtle Beach, SC with Greyhound for as low as $142 (€115). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Syracuse, NY to Myrtle Beach, SC
Find answers to the most common questions about traveling from Syracuse, NY to Myrtle Beach, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Myrtle Beach, SC, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Syracuse, NY to Myrtle Beach, SC
Most popular bus connections from Syracuse, NY
More options for your journey from Syracuse, NY to Myrtle Beach, SC
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