Travel Information
Compare bus, train, and flight for Harrisburg, PA to Detroit, MI
Omio recommends booking the bus as it is the most popular option from Harrisburg, PA to Detroit, MI among Omio's users. If you are prioritising price take the bus with prices starting from $69. For those with little time consider booking a flight which can get you there in 4h 54m. The ticket price range depends on the travel mode: a bus costs an average of $69, and a flight costs an average of $361.
Distance: 349 miles (563 km)
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
$93 Average price Cheapest | $441 Average price | $192 Average price |
13h 11m Average total duration 12h 41m Onboard + 30m Additional time* | 7h 54m Average total duration Fastest 4h 54m Onboard + 3h 0m Additional time* | 22h 17m Average total duration 21h 47m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Harrisburg, PA to Detroit, MI bus times
The table below shows live departures for Harrisburg, PA to Detroit, MI buses for today, Sunday, March 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:05 PM Harrisburg, PA | 13h05 | 9:10 AM Detroit, MI | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Harrisburg, PA to Detroit, MI by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Harrisburg, PA to Detroit, MI buses with Omio?
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Harrisburg, PA to Detroit, MI.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Harrisburg, PA to Detroit, MI.
Journey information
Overview: Bus from Harrisburg, PA to Detroit, MI
Buses from Harrisburg, PA to Detroit, MI run on average 4 times per day, taking around 12h 41m. Cheap bus tickets for this journey start at $69 (€56) if you book in advance.
There are 1 buses per day. The earliest bus runs at 02:30, the last at 23:55. The fastest bus covers the 349 miles (563 km) distance in 12h 50m.
Distance 349 miles (563 km) |
Average bus duration 12h 41m |
Cheapest ticket price $69 (€56) |
Buses per day 4 |
Direct buses 1 |
Fastest bus 12h 50m |
First bus 02:30 |
Last bus 23:55 |
Cheapest month Aug |
Cheapest day Thu |
High season Oct - Dec |
Low season Jan - Mar |
Busiest day Wed |
Least busy day Wed |
Bus providers: Greyhound from Harrisburg, PA to Detroit, MIYou can travel by bus between Harrisburg, PA to Detroit, MI with Greyhound for as low as $69 (€56). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Harrisburg, PA to Detroit, MI
Find answers to the most common questions about traveling from Harrisburg, PA to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Detroit Institute of Arts, a renowned museum housing over 65,000 artworks from various cultures and eras
- The Henry Ford, a sprawling complex dedicated to American innovation and history, featuring the Henry Ford Museum and Greenfield Village
- Detroit Riverwalk, a scenic promenade along the Detroit River offering views, parks, and recreational activities
- Belle Isle Park, a 982-acre island park with attractions like an aquarium, conservatory, and nature trails
- Guardian Building, an iconic skyscraper known for its stunning Art Deco architecture and vibrant interior design.
- Motown Museum, the iconic birthplace of the Motown Sound offering guided tours of the historic recording studios
- Eastern Market, a vibrant public market offering fresh produce, local goods, and a lively atmosphere with events and street art
- Detroit Historical Museum, showcasing the rich history of Detroit through engaging exhibits and interactive displays
- Detroit Zoo, featuring a wide variety of animals and immersive habitats
- Comerica Park, a baseball stadium offering games, tours, and family-friendly activities.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Harrisburg, PA to Detroit, MI
Most popular bus connections from Harrisburg, PA
More options for your journey from Harrisburg, PA to Detroit, MI
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