The cheapest and fastest buses from Harrisburg, PA to Detroit, MI
Cheapest price
$68
Average price
$68
Fastest journey
18 h 5 m
Average duration
18 h 5 m
Buses per day
1
Distance
563 km
The best way to find a cheap bus ticket from Harrisburg, PA to Detroit, MI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Detroit, MI will cost around $68 if you buy it on the day, but the cheapest tickets can be found for only $68.
Of the 1 buses that leave Harrisburg, PA for Detroit, MI on Fri, Nov 07, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct buses cover the 563 km distance in an average of 18 h 5 m but if you time it right, some buses will get you there in just 18 h 5 m .
On Fri, Nov 07 the slowest buses will take 18 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus, train, and flight for Harrisburg, PA to Detroit, MI
Omio recommends booking the bus as it is the most popular option from Harrisburg, PA to Detroit, MI among Omio's users. If you are prioritising price take the bus with prices starting from €52. For those with little time consider booking a flight which can get you there in 4h 36m. The ticket price range depends on the travel mode: a bus costs an average of €52, and a flight costs an average of €305.
Distance: 349 miles (563 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
€54 Average price Cheapest | €152 Average price | €305 Average price |
13h 8m Average total duration 12h 38m Onboard + 30m Additional time* | 17h 29m Average total duration 16h 59m Onboard + 30m Additional time* | 7h 36m Average total duration Fastest 4h 36m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Harrisburg, PA to Detroit, MI bus times
The table below shows live departures for Harrisburg, PA to Detroit, MI buses for today, Thursday, November 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:40 PM Harrisburg, PA | 18h05 | 12:45 PM Detroit, MI | 0 transfersDirect | |
![]() | 11:55 PM Harrisburg, PA | 12h50 | 12:45 PM Detroit, MI | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Harrisburg, PA to Detroit, MI by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 07
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Journey information
Overview: Bus from Harrisburg, PA to Detroit, MI
Buses from Harrisburg, PA to Detroit, MI run on average 5 times per day, taking around 12h 38m. Cheap bus tickets for this journey start at $64 (€52) if you book in advance.
There are 1 buses per day. The earliest bus runs at 02:00, the last at 22:05. The fastest bus covers the 349 miles (563 km) distance in 18h 5m.
Distance 349 miles (563 km) |
Average bus duration 12h 38m |
Cheapest ticket price $64 (€52) |
Buses per day 5 |
Direct buses 1 |
Fastest bus 18h 5m |
First bus 02:00 |
Last bus 22:05 |
Bus providers: Greyhound from Harrisburg, PA to Detroit, MIYou can travel by bus between Harrisburg, PA to Detroit, MI with Greyhound for as low as $64 (€52). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Harrisburg, PA to Detroit, MI
Find answers to the most common questions about traveling from Harrisburg, PA to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Detroit Institute of Arts, a renowned museum housing over 65,000 artworks from various cultures and eras
- The Henry Ford, a sprawling complex dedicated to American innovation and history, featuring the Henry Ford Museum and Greenfield Village
- Detroit Riverwalk, a scenic promenade along the Detroit River offering views, parks, and recreational activities
- Belle Isle Park, a 982-acre island park with attractions like an aquarium, conservatory, and nature trails
- Guardian Building, an iconic skyscraper known for its stunning Art Deco architecture and vibrant interior design.
- Motown Museum, the iconic birthplace of the Motown Sound offering guided tours of the historic recording studios
- Eastern Market, a vibrant public market offering fresh produce, local goods, and a lively atmosphere with events and street art
- Detroit Historical Museum, showcasing the rich history of Detroit through engaging exhibits and interactive displays
- Detroit Zoo, featuring a wide variety of animals and immersive habitats
- Comerica Park, a baseball stadium offering games, tours, and family-friendly activities.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
To find the cheapest bus tickets for your trip from Harrisburg, PA to Detroit, MI, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Harrisburg, PA to Detroit, MI
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