- Must visit
Detroit Institute of Arts
World-class museum with Diego Rivera’s Detroit Industry murals and major collections spanning ancient to contemporary art.
Cheapest price
$70
Average price
$72
Fastest journey
13 h 5 m
Average duration
13 h 15 m
Buses per day
2
Distance
563 km
The best way to find a cheap bus ticket from Harrisburg, PA to Detroit, MI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Detroit, MI will cost around $72 if you buy it on the day, but the cheapest tickets can be found for only $70.
Of the 2 buses that leave Harrisburg, PA for Detroit, MI on Thu, Aug 06, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 06 the direct buses cover the 563 km distance in an average of 13 h 15 m but if you time it right, some buses will get you there in just 13 h 5 m .
On Thu, Aug 06 the slowest buses will take 13 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
· 

· Omio recommends booking the bus as it is the most popular option from Harrisburg, PA to Detroit, MI among Omio's users. If you are prioritising price take the bus with prices starting from $69. For those with little time consider booking a flight which can get you there in 7h 15m. The ticket price range depends on the travel mode: a bus costs an average of $69, and a flight costs an average of $426.
Distance: 349 miles (563 km)
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
$89 Average price Cheapest | $538 Average price | $201 Average price | $98 Average price (fuel + tolls) |
13h 18m Average total duration 12h 48m Onboard + 30m Additional time* | 10h 15m Average total duration Fastest 7h 15m Onboard + 3h 0m Additional time* | 36h 9m Average total duration 35h 39m Onboard + 30m Additional time* | 6h 59m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Harrisburg, PA to Detroit, MI:
A bus is $112 less than a train for this route with tickets for a train from Harrisburg, PA to Detroit, MI costing on average $201.
A bus is $449 less than a flight for this route with tickets for a flight from Harrisburg, PA to Detroit, MI costing on average $538.
Other travel options to Detroit, MI take longer:
Bus takes on average 12h 48m.
Train takes on average 35h 39m.
Tickets start at around $89 compared to roughly $98 in fuel and tolls — a saving of about $8. The journey takes 12h 48m versus 6h 59m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 01:05AM | Arrival Time 02:10PM | Duration 13h05 | Departure days Mon | Cheapest price $75 |
Operator Greyhound | Departure Time 02:15AM | Arrival Time 03:40PM | Duration 13h25 | Departure days Mon, Tue, Wed, Thu, Sat | Cheapest price $61 |
Operator Greyhound | Departure Time 02:30AM | Arrival Time 03:40PM | Duration 13h10 | Departure days Fri | Cheapest price $66 |
Operator Greyhound | Departure Time 08:05PM | Arrival Time 09:10AM | Duration 13h05 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $71 |
The table below shows live departures for Harrisburg, PA to Detroit, MI buses for today, Wednesday, August 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 8:05 PM Harrisburg, Market St (Bus Station), PA | 13h05 | 9:10 AM Detroit, Greyhound Terminal | 0 transfersDirect | |
| Thursday, August 6 | |||||
· | 2:15 AM Harrisburg, Market St (Bus Station), PA | 13h25 | 3:40 PM Detroit, Greyhound Terminal | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Harrisburg, PA to Detroit, MI run on average 4 times per day, taking around 12h 48m. Cheap bus tickets for this journey start at $69 if you book in advance.
There are 1 buses per day. The earliest bus runs at 02:30, the last at 23:55. The fastest bus covers the 349 miles (563 km) distance in 13h 5m.
Distance 349 miles (563 km) |
Average bus duration 12h 48m |
Cheapest ticket price $69 |
Buses per day 4 |
Direct buses 1 |
Fastest bus 13h 5m |
First bus 2:30 AM |
Last bus 11:55 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
Discover the best of Detroit, MI — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Detroit, MI trip today.
World-class museum with Diego Rivera’s Detroit Industry murals and major collections spanning ancient to contemporary art.
Immersive museum of African American history, culture, and achievement with strong regional and national storytelling.
Motown’s original Studio A preserves the sound and stories behind legendary recordings that shaped popular music worldwide.
Riverfront promenade with public art, plazas, and skyline views; one of the city’s best places for a scenic walk.
Large island park with gardens, trails, beaches, and major attractions, offering a nature escape minutes from downtown.
Revived public square at the city center, hosting events, seasonal programming, and easy access to downtown landmarks.
A square deep-dish pizza with a crisp, caramelized cheese edge and striped sauce. It is Detroit’s signature pie, born in blue steel auto pans.
A hot dog topped with chili, mustard, and diced onions on a steamed bun. It is a classic Detroit street food tied to Greek-American diners.
A layered sandwich of corned beef, swiss cheese, coleslaw, and Russian dressing on grilled rye. It is a beloved deli staple in metro Detroit.
Acclaimed fine-dining restaurant focused on seasonal tasting menus and polished service. One of Detroit’s top special-occasion destinations.
Beloved Eastern Market bakery known for paczki, cakes, and old-school sweets. Expect a busy, nostalgic counter-service experience.
Historic downtown institution famous for Detroit-style square pizza in a lively, casual setting with old-school local character.
Moderate for US city breaks: hotels and dining are mid-priced, transit is limited, and car or rideshare costs can raise daily spend.
Tip 18-20% in restaurants, $1-2 per drink at bars, 10-15% for taxis, and spare change or about 10% in cafes if there is table service.
Find answers to the most common questions about traveling from Harrisburg, PA to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

Most Harrisburg, PA to Detroit, MI buses use the Harrisburg, Market St (Bus Station) to Detroit, Greyhound Terminal station pair. Use this guide to compare Harrisburg, PA and Detroit, MI bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Harrisburg, Market St (Bus Station) is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Market St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free WiFi inside the station. ATMs are available at Harrisburg, Market St (Bus Station).
Ticket office support is available at Harrisburg, Market St (Bus Station).
Available at Harrisburg, Market St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Market St (Bus Station): Wheelchair accessible with ramps.
Harrisburg, Chestnut Street / South 4th Street is 1 km from Harrisburg city centre. Public transport options include:
Harrisburg, Chestnut Street / South 4th Street has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Harrisburg, Chestnut Street / South 4th Street. ATMs are available at Harrisburg, Chestnut Street / South 4th Street.
Ticket office support is available at Harrisburg, Chestnut Street / South 4th Street.
Available at Harrisburg, Chestnut Street / South 4th Street: Parking, Taxis, WC.
Accessibility facilities are available at Harrisburg, Chestnut Street / South 4th Street: Accessible by wheelchair via main entrance.
Detroit, Greyhound Terminal is 1 km from Detroit city centre. Public transport options include:
Detroit, Greyhound Terminal has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food and coffee shops available.
Free Wi-Fi available in waiting areas. ATMs are aTM located near the main entrance.
Ticket office support is available at Detroit, Greyhound Terminal.
Available at Detroit, Greyhound Terminal: Parking, Taxis, WC.
Accessibility facilities are available at Detroit, Greyhound Terminal: Wheelchair accessible facilities available.
Here are some other resources that might have the information you need