- Must visit
Detroit Institute of Arts
Major fine arts museum known for its encyclopedic collection and Diego Rivera’s Detroit Industry Murals.
Cheapest price
$106
Average price
$106
Fastest journey
13 h 5 m
Average duration
13 h 5 m
Buses per day
1
Distance
563 km
The best way to find a cheap bus ticket from Harrisburg, PA to Detroit, MI is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Harrisburg, PA to Detroit, MI will cost around $106 if you buy it on the day, but the cheapest tickets can be found for only $106.
Of the 1 buses that leave Harrisburg, PA for Detroit, MI on Tue, Jun 23, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Jun 23 the direct buses cover the 563 km distance in an average of 13 h 5 m but if you time it right, some buses will get you there in just 13 h 5 m .
On Tue, Jun 23 the slowest buses will take 13 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Omio recommends booking the bus as it is the most popular option from Harrisburg, PA to Detroit, MI among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a flight which can get you there in 7h 15m. The ticket price range depends on the travel mode: a bus costs an average of $68, and a flight costs an average of $424.
Distance: 349 miles (563 km)
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
$89 Average price Cheapest | $200 Average price | $535 Average price | $97 Average price (fuel + tolls) |
13h 18m Average total duration 12h 48m Onboard + 30m Additional time* | 36h 9m Average total duration 35h 39m Onboard + 30m Additional time* | 10h 15m Average total duration Fastest 7h 15m Onboard + 3h 0m Additional time* | 6h 59m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Harrisburg, PA to Detroit, MI:
A bus is $111 (€91) less than a train for this route with tickets for a train from Harrisburg, PA to Detroit, MI costing on average $200 (€164).
A bus is $446 (€365) less than a flight for this route with tickets for a flight from Harrisburg, PA to Detroit, MI costing on average $535 (€438).
Other travel options to Detroit, MI take longer:
Bus takes on average 12h 48m.
Train takes on average 35h 39m.
Tickets start at around $89 (€73) compared to roughly $97 (€80) in fuel and tolls — a saving of about $8 (€7). The journey takes 12h 48m versus 6h 59m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Greyhound.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:05AM | Arrival Time 01:10PM | Duration 13h05 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $86 |
Operator Greyhound | Departure Time 01:05AM | Arrival Time 02:10PM | Duration 13h05 | Departure days Mon, Fri, Sat, Sun | Cheapest price $68 |
Operator Greyhound | Departure Time 02:30AM | Arrival Time 03:40PM | Duration 13h10 | Departure days Wed | Cheapest price $100 |
Operator Greyhound | Departure Time 06:30AM | Arrival Time 07:40PM | Duration 13h10 | Departure days Sat | Cheapest price $106 |
Operator Greyhound | Departure Time 08:05PM | Arrival Time 09:10AM | Duration 13h05 | Departure days Wed | Cheapest price $75 |
The table below shows live departures for Harrisburg, PA to Detroit, MI buses for today, Sunday, June 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:05 AM Harrisburg, PA | 13h05 | 2:10 PM Detroit, MI | 0 transfersDirect | |
| Monday, June 22 | |||||
![]() | 12:05 AM Harrisburg, PA | 13h05 | 1:10 PM Detroit, MI | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Harrisburg, PA to Detroit, MI run on average 4 times per day, taking around 12h 48m. Cheap bus tickets for this journey start at $68 (€56) if you book in advance.
There are 1 buses per day. The earliest bus runs at 02:30, the last at 23:55. The fastest bus covers the 349 miles (563 km) distance in 13h 5m.
Distance 349 miles (563 km) |
Average bus duration 12h 48m |
Cheapest ticket price $68 (€56) |
Buses per day 4 |
Direct buses 1 |
Fastest bus 13h 5m |
First bus 2:30 AM |
Last bus 11:55 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Wed |
Discover the best of Detroit — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Detroit trip today.
Major fine arts museum known for its encyclopedic collection and Diego Rivera’s Detroit Industry Murals.
Large museum in the Detroit area showcasing transportation, industry, design, and iconic American artifacts.
Historic Hitsville U.S.A. museum preserving the story of Motown Records and its legendary artists.
Popular waterfront promenade with skyline views, public art, and easy walking between downtown and riverfront parks.
Island park with gardens, trails, water views, and several cultural attractions, popular with locals and visitors.
Historic market district famous for murals, weekend markets, and one of Detroit’s strongest local atmospheres.
A rectangular, deep-pan pizza with a thick yet airy crust, caramelized cheese edges, and sauce layered on top. It is one of Detroit’s most iconic local foods.
A hot dog in a bun topped with chili, mustard, and chopped onions. The Detroit coney is a classic local fast-food staple tied to the city’s Greek-American diner tradition.
A traditional Detroit float made with Vernors ginger ale and vanilla ice cream. Despite the name, it is a distinctly Detroit dessert drink.
A long-running Hamtramck favorite for hearty Polish dishes in a warm, traditional basement setting near Detroit.
A respected modern Detroit restaurant known for seasonal small plates, strong cocktails, and an upscale but relaxed atmosphere.
A polished downtown dining room in the Detroit Foundation Hotel, known for contemporary American cooking and stylish surroundings.
Moderate for U.S. city travel. Hotels vary widely, while casual dining, coffee, and local transport are usually manageable for most visitors.
Tip 18-20% in restaurants before tax. Bartenders: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 1-5. Not usually expected for counter service, but appreciated.
Find answers to the most common questions about traveling from Harrisburg, PA to Detroit, MI by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Detroit, MI, this guide helps you travel smarter and with confidence.

Most Harrisburg, PA to Detroit, MI buses use the Harrisburg, Market St (Bus Station) to Detroit, Greyhound Terminal station pair. Use this guide to compare Harrisburg, PA and Detroit, MI bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need