Journey information
Overview: Bus from Durham, NC to Gainesville, FL
Buses from Durham, NC to Gainesville, FL run on average 8 times per day, taking around 24h 0m. Cheap bus tickets for this journey start at $100 (€82) if you book in advance.
The earliest bus runs at 01:10, the last at 22:40. The fastest bus covers the 480 miles (774 km) distance in 24h 0m.
Distance 480 miles (774 km) |
Average bus duration 24h 0m |
Cheapest ticket price $100 (€82) |
Buses per day 8 |
Fastest bus 24h 0m |
First bus 01:10 |
Last bus 22:40 |
FAQs: Bus from Durham, NC to Gainesville, FL
Find answers to the most common questions about traveling from Durham, NC to Gainesville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Gainesville, FL, this guide helps you travel smarter and with confidence.

- Florida Museum of Natural History, featuring extensive exhibits on Florida's flora, fauna, and cultural heritage
- Kanapaha Botanical Gardens, a 62-acre garden showcasing diverse plant collections and scenic landscapes
- Devil's Millhopper Geological State Park, a unique geological formation with a large sinkhole and nature trails
- Paynes Prairie Preserve State Park, offering wildlife viewing, hiking, and panoramic views of the prairie ecosystem
- Samuel P. Harn Museum of Art, housing a diverse collection of artworks from around the world.
- Explore the vibrant local art scene at the Gainesville Artwalk, featuring galleries and live performances
- Visit the Santa Fe College Teaching Zoo, home to a variety of animal species and educational programs
- Enjoy a day of outdoor activities at Lake Wauburg, offering boating, picnicking, and climbing walls
- Discover the historic Haile Homestead, known for its " Talking Walls" filled with writings from the 19th century
- Attend a performance at the Hippodrome Theatre, showcasing plays, films, and special events.
To find the cheapest bus tickets for your trip from Durham, NC to Gainesville, FL, follow these tips:
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