- Must visit
Florida Museum of Natural History
The state’s official natural history museum, known for Florida fossils, biodiversity exhibits, and family-friendly displays. A top cultural stop near the university.
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The cheapest and fastest buses from Durham, NC to Gainesville, FL
Showing times and prices for May 31
Cheapest price
$112
Average price
$112
Fastest journey
1 d 14 h 45 m
Average duration
1 d 14 h 45 m
Buses per day
1
Distance
774 km
Cheap tickets
The best way to find a cheap bus ticket from Durham, NC to Gainesville, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Durham, NC to Gainesville, FL will cost around $112 if you buy it on the day, but the cheapest tickets can be found for only $112.
Fast buses
It's difficult to get from Durham, NC to Gainesville, FL without transferring at least 2 times.
9:15 PM38h45Durham, NC12:00 PMGainesville, FL$1121One-way2 transfers
- 9:15 PM38h45Durham, NC12:00 PMGainesville, FL$1121One-way2 transfers
Travel Information
Compare bus, train, and flight for Durham, NC to Gainesville, FL
Omio recommends booking the flight as it is the most popular option from Durham, NC to Gainesville, FL among Omio's users. If you are prioritising price take the bus with prices starting from $115. For those with little time consider booking a flight which can get you there in 5h 51m. The ticket price range depends on the travel mode: a bus costs an average of $115, and a flight costs an average of $460.
Distance: 480 miles (774 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$183 Average price Cheapest | $485 Average price | $235 Average price | $107 Average price (fuel + tolls) |
19h 50m Average total duration 19h 20m Onboard + 30m Additional time* | 8h 51m Average total duration Fastest 5h 51m Onboard + 3h 0m Additional time* | 16h 19m Average total duration 15h 49m Onboard + 30m Additional time* | 8h 2m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Durham, NC to Gainesville, FL is a bus with an average price of $183 (€147).
This is compared to other travel options from Durham, NC to Gainesville, FL:
A bus is $52 (€42) less than a train for this route with tickets for a train from Durham, NC to Gainesville, FL costing on average $235 (€189).
A bus is $302 (€243) less than a flight for this route with tickets for a flight from Durham, NC to Gainesville, FL costing on average $485 (€391).
The fastest way to travel from Durham, NC to Gainesville, FL is by flight with an average journey time of 5h 51m.
Other travel options to Gainesville, FL take longer:
Train takes on average 15h 49m.
Bus takes on average 19h 20m.
It's helpful to compare your options as there are 3 ways to travel between Durham, NC and Gainesville, FL including taking a bus, train, and flight.
We recommend using the bus as it is the most popular way to get from Durham, NC to Gainesville, FL among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Durham, NC to Gainesville, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 08:55AM | Arrival Time 01:15AM | Duration 16h20 | Departure days Thu | Cheapest price $251 |
Operator Greyhound | Departure Time 08:05PM | Arrival Time 06:25PM | Duration 22h20 | Departure days Fri | Cheapest price $115 |
Operator Flixbus USA | Departure Time 09:15PM | Arrival Time 12:00PM | Duration 38h45 | Departure days Wed, Sun | Cheapest price $112 |
Compare prices and tickets Durham, NC to Gainesville, FL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Durham, NC to Gainesville, FL buses with Omio?
FlixBus operates all buses services from Durham, NC to Gainesville, FL.
Omio is an official ticket reseller for all your travel options from Durham, NC to Gainesville, FL.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Durham, NC to Gainesville, FL.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Durham, NC to Gainesville, FL.
Journey information
Overview: Bus from Durham, NC to Gainesville, FL
USAUSA
Buses from Durham, NC to Gainesville, FL run on average 9 times per day, taking around 19h 20m. Cheap bus tickets for this journey start at $115 (€92) if you book in advance.
The earliest bus runs at 00:35, the last at 22:40. The fastest bus covers the 480 miles (774 km) distance in 16h 20m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 480 miles (774 km) |
Average bus duration 19h 20m |
Cheapest ticket price $115 (€92) |
Buses per day 9 |
Fastest bus 16h 20m |
First bus 12:35 AM |
Last bus 10:40 PM |
Cheapest Month Nov |
Cheapest Day Fri |
High Season Oct - Dec |
Low Season Apr - Jun |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus from Durham, NC to Gainesville, FLYou can travel by bus between Durham, NC to Gainesville, FL with FlixBus for as low as $115 (€92). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
38h 45m
Cheapest Price
$112 (€90)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Gainesville
Things to do in Gainesville
Discover the best of Gainesville — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Gainesville trip today.
- Must visit
Harn Museum of Art
A major university art museum with Asian, African, contemporary, and photography collections. Widely regarded for its strong exhibitions and free admission.
- Recommended
Cade Museum for Creativity and Invention
A hands-on museum focused on science, invention, and creativity, inspired by the inventor of Gatorade. Popular with families and visitors seeking interactive exhibits.
- Must visit
Downtown Gainesville
The city’s main walkable district, known for historic streetscapes, public art, events, and nightlife. A priority area for first-time visitors.
- Must visit
Depot Park
A highly popular urban park with lawns, water features, trails, and scenic views. Frequently featured on social media and excellent for a relaxed walk.
- Must visit
Paynes Prairie Preserve State Park
A vast natural preserve south of the city with trails, wildlife viewing, and broad prairie views. One of the area’s signature outdoor destinations.
Florida Gator Tail
A North Florida specialty made from alligator tail meat, usually fried or blackened. It is a regional dish strongly associated with Florida's hunting and swamp-food traditions.
Southern Fried Catfish
A classic in North Central Florida and the wider South, typically cornmeal-coated and fried. It is popular at local fish camps and casual family restaurants.
- Gluten-free
Smoked Barbecue Pork
Slow-smoked pork with regional Southern barbecue flavors, often served with beans, slaw, and sauce. Barbecue is a staple comfort food in Gainesville and inland Florida.
Embers Wood Grill
A well-known higher-end steakhouse featuring wood-grilled meats, seafood, and an elegant setting. Suitable for a polished dinner out.
Satchel's Pizza
One of Gainesville's most recognizable local restaurants, famous for pizza, salads, and quirky artistic decor. It has a fun, family-friendly atmosphere.
Dragonfly Sushi & Sake Company
An established upscale-casual restaurant in downtown Gainesville, known for creative sushi, Japanese small plates, and a lively social atmosphere.
United States Dollar
Moderate for U.S. travel. Student-focused dining keeps casual meals affordable, while hotels and upscale dining cost more on busy weekends and event dates.
Average meal costs
- Budget
- USD 10-15 for fast food or casual takeout.
- Mid-range
- USD 18-35 per person at a mid-range restaurant.
- Fine dining
- USD 50-90 per person at upscale restaurants.
- Coffee
- USD 3-6 for a regular coffee or latte.
Tipping culture
Tip 15-20% at restaurants; 20% for great service. Tip USD 1-2 per drink at bars, round up taxis or add 10-15%, and tip hotel staff USD 2-5 as appropriate.
FAQs: Bus from Durham, NC to Gainesville, FL
Find answers to the most common questions about traveling from Durham, NC to Gainesville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Gainesville, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Durham, NC to Gainesville, FL can start from as little as $115 (€92) when you book in advance. The average bus ticket price for Durham, NC to Gainesville, FL is $183 (€147) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Durham, NC to Gainesville, FL is 16h 20m to travel the 480 miles (774 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Durham, NC to Gainesville, FL leaves at 12:35 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Durham, NC to Gainesville, FL leaves at 10:40 PM.
There are 9 buses a day from Durham, NC to Gainesville, FL which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Durham, NC to Gainesville, FL, you can count on FlixBus for the best way to get you to Gainesville, FL. You can also check all possible bus companies who offer a service between Durham, NC and Gainesville, FL and compare the amenities they offer before buying a bus ticket.
A trip to Gainesville, FL from Durham, NC is worth doing but not as a day trip with a journey time of 16h 20m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Durham, NC to Gainesville, FL is November.
It's helpful to compare your options as there are 3 ways to travel between Durham, NC and Gainesville, FL including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the bus from Durham, NC to Gainesville, FL:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Durham, NC to Gainesville, FL for bus company FlixBus.
Some of the most interesting sights to explore in Gainesville, FL are:
- Florida Museum of Natural History, featuring extensive exhibits on Florida's flora, fauna, and cultural heritage
- Kanapaha Botanical Gardens, a 62-acre garden showcasing diverse plant collections and scenic landscapes
- Devil's Millhopper Geological State Park, a unique geological formation with a large sinkhole and nature trails
- Paynes Prairie Preserve State Park, offering wildlife viewing, hiking, and panoramic views of the prairie ecosystem
- Samuel P. Harn Museum of Art, housing a diverse collection of artworks from around the world.
The best things to do in Gainesville, FL include:
- Explore the vibrant local art scene at the Gainesville Artwalk, featuring galleries and live performances
- Visit the Santa Fe College Teaching Zoo, home to a variety of animal species and educational programs
- Enjoy a day of outdoor activities at Lake Wauburg, offering boating, picnicking, and climbing walls
- Discover the historic Haile Homestead, known for its "Talking Walls" filled with writings from the 19th century
- Attend a performance at the Hippodrome Theatre, showcasing plays, films, and special events.
Whether you can cancel your bus ticket from Durham, NC to Gainesville, FL depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Durham, NC to Gainesville, FL.
Yes, the following luggage options are included when booking a bus ticket from Durham, NC to Gainesville, FL:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Durham, NC to Gainesville, FL:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Durham, NC to Gainesville, FL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Durham, NC to Gainesville, FL with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Durham, NC to Gainesville, FL with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Durham, NC to Gainesville, FL with the following bus company: FlixBus.
Since neither Durham, NC nor Gainesville, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Durham, NC to Gainesville, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Gainesville, FL, travelers should be cautious of petty theft, especially in crowded areas like downtown and near the University of Florida campus. Common scams include overcharging by unofficial taxi or ride-share drivers and ticket scams for local events. It's important to use authorized transportation services and stay in well-lit, populated areas at night to enhance personal safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Durham, NC to Gainesville, FL
Durham
Gainesville
The major bus station for departures in Durham is Durham, W Pettigrew St (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Durham, W Pettigrew St (Greyhound Bus Station) for your trip from Durham to Gainesville.
Durham, W Pettigrew St (Greyhound Bus Station)
information
The major bus station for arrivals in Gainesville is Gainesville, Rosa Parks Transfer station. Find all the information you need to know about services, amenities and connections at Gainesville, Rosa Parks Transfer station for your trip to Gainesville from Durham.
Gainesville, Rosa Parks Transfer station
information
Gainesville, NW 23rd St (North Walmart Supercenter)
information
Most popular bus connections from Durham, NC
More options for your journey from Durham, NC to Gainesville, FL
Here are some other resources that might have the information you need
Most popular buses to and from Gainesville, FL and Durham, NC
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