- Recommended
The Franklin G. Burroughs-Simeon B. Chapin Art Museum
Compact museum sharing regional military history through uniforms, weapons, artifacts, and exhibits on local veterans and conflicts.
The best way to find a cheap bus ticket from Durham, NC to Myrtle Beach, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Durham, NC to Myrtle Beach, SC will cost around €80 if you buy it on the day, but the cheapest tickets can be found for only €77.
On Tue, Nov 03, we found 2 buses from Durham, NC to Myrtle Beach, SC, including 2 direct services.
On Tue, Nov 03 the direct buses cover the 256 km distance in an average of 8 h but if you time it right, some buses will get you there in just 8 h .
On Tue, Nov 03 the slowest buses will take 8 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Buses from Durham, NC to Myrtle Beach, SC run on average 2 times per day, taking around 10h 43m. Cheap bus tickets for this journey start at €41 if you book in advance.
The earliest bus runs at 12:45, the last at 13:55. The fastest bus covers the 159 miles (256 km) distance in 10h 35m.
Distance 159 miles (256 km) |
Average bus duration 10h 43m |
Cheapest ticket price €41 |
Buses per day 2 |
Fastest bus 10h 35m |
First bus 12:45 PM |
Last bus 1:55 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Oct - Dec |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Durham, NC to Myrtle Beach, SC.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 04:55AM | Arrival Time 04:45PM | Duration 11h50 | Departure days Mon | Cheapest price €71 |
Operator Greyhound USA | Departure Time 09:10AM | Arrival Time 05:10PM | Duration 8h00 | Departure days Sat, Sun | Cheapest price €53 |
Operator Greyhound | Departure Time 01:10PM | Arrival Time 09:10PM | Duration 8h00 | Departure days Tue, Wed, Thu, Fri | Cheapest price €46 |
Operator Greyhound | Departure Time 02:10PM | Arrival Time 10:10PM | Duration 8h00 | Departure days Tue, Wed, Thu, Fri | Cheapest price €57 |
The table below shows live departures for Durham, NC to Myrtle Beach, SC buses for today, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· · · | 4:55 AM Durham Station | 11h50 | 4:45 PM Myrtle Beach, N Oak St (Bus Station) | 3 transfers | |
This is the last bus of the day. | |||||
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Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Myrtle Beach, SC — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Myrtle Beach, SC trip today.
Compact museum sharing regional military history through uniforms, weapons, artifacts, and exhibits on local veterans and conflicts.
Beachfront art museum with rotating exhibitions, community programs, and regional works in a former oceanfront residence.
Hands-on science museum for families with interactive exhibits on space, physics, and natural science at Broadway at the Beach.
Popular entertainment district around a lake with wide walking paths, shops, attractions, and evening activity close to the beach.
Oceanfront district combining the boardwalk, beach access, entertainment, and public spaces for an easy first visit to the city.
Upscale shopping and walking area with landscaped streets, boutiques, lakefront paths, and seasonal events in a relaxed setting.
Lowcountry boil with shrimp, sausage, corn, and potatoes, seasoned and boiled together. A Carolina coast staple popular at beach gatherings and seafood feasts.
She-crab soup is a rich coastal soup made with crab meat, crab roe, cream, and sherry. It is a classic South Carolina specialty served along the Grand Strand.
Shrimp and grits pairs local shrimp with creamy grits, often with bacon or gravy. It is one of the most iconic dishes in South Carolina coastal cooking.
Casual local favorite for Southern breakfast and brunch, especially shrimp and grits, biscuits, and hearty comfort food.
Upscale seafood restaurant known for refined Lowcountry dishes, steaks, and a polished dining room near the ocean.
Lively, long-running waterfront spot on the MarshWalk serving fresh local seafood, sushi, and regional favorites in a casual setting.
Moderate for a US beach city: hotels rise in peak season, dining is mid-priced, and car-based travel adds parking and fuel costs.
Tip 18-20% at restaurants, more for excellent service. Taxis usually 10-15%. Small tips are optional at cafes.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Myrtle Beach, SC.
Find answers to the most common questions about traveling from Durham, NC to Myrtle Beach, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Myrtle Beach, SC, this guide helps you travel smarter and with confidence.

Most Durham, NC to Myrtle Beach, SC buses use the Durham, W Pettigrew St (Greyhound Bus Station) to Myrtle Beach, N Oak St (Bus Station) station pair. Use this guide to compare Durham, NC and Myrtle Beach, SC bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Myrtle Beach, N Oak St (Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Myrtle Beach, N Oak St (Bus Station). ATMs are available at Myrtle Beach, N Oak St (Bus Station).
Ticket office support is available at Myrtle Beach, N Oak St (Bus Station).
Available at Myrtle Beach, N Oak St (Bus Station): Parking, Taxis, WC.
Accessibility facilities are available at Myrtle Beach, N Oak St (Bus Station): Wheelchair accessible entry available.
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