- Must visit
Roberson Museum and Science Center
Regional museum with art, history, and science exhibits in a landmark mansion complex, plus a planetarium and observatory.
The best way to find a cheap bus ticket from Durham, NC to Binghamton, NY is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Durham, NC to Binghamton, NY will cost around $152 if you buy it on the day, but the cheapest tickets can be found for only $117.
It's difficult to get from Durham, NC to Binghamton, NY without transferring at least once.

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Buses from Durham, NC to Binghamton, NY run on average 5 times per day, taking around 14h 43m. Cheap bus tickets for this journey start at $92 if you book in advance.
The earliest bus runs at 05:20, the last at 22:35. The fastest bus covers the 451 miles (726 km) distance in 13h 0m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Durham, NC to Binghamton, NY.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 02:05AM | Arrival Time 12:20AM | Duration 22h15 | Departure days Sat | Cheapest price $199 |
Operator Greyhound | Departure Time 02:05AM | Arrival Time 06:20AM | Duration 28h15 | Departure days Tue | Cheapest price $176 |
Operator Flixbus USA | Departure Time 02:40AM | Arrival Time 05:15PM | Duration 14h35 | Departure days Tue, Wed, Sat | Cheapest price $117 |
Operator Flixbus USA | Departure Time 03:50AM | Arrival Time 08:00PM | Duration 16h10 | Departure days Tue, Sat | Cheapest price $117 |
Operator Greyhound USA | Departure Time 09:10AM | Arrival Time 02:20AM | Duration 17h10 | Departure days Tue, Wed, Sun | Cheapest price $175 |
Operator Greyhound | Departure Time 09:05PM | Arrival Time 01:40PM | Duration 16h35 | Departure days Thu | Cheapest price $160 |
Operator Flixbus USA | Departure Time 09:15PM | Arrival Time 01:55PM | Duration 16h40 | Departure days Tue, Wed, Sun | Cheapest price $164 |
The table below shows live departures for Durham, NC to Binghamton, NY buses for today, Tuesday, November 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:15 PM Durham, NC | 16h40 | 1:55 PM Binghamton, NY | 2 transfers | |
| Wednesday, November 4 | |||||
![]() | 2:40 AM Durham, NC | 14h35 | 5:15 PM Binghamton, NY | 1 transfer | |
![]() | 9:10 AM Durham, NC | 17h10 | 2:20 AM Binghamton, NY | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Durham, NC to Binghamton, NY with FlixBus and Greyhound. Overnight buses available on this route with FlixBus and Greyhound. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Binghamton, NY — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Binghamton, NY trip today.
Regional museum with art, history, and science exhibits in a landmark mansion complex, plus a planetarium and observatory.
Historic mansion museum showcasing Victorian interiors, local history, and guided tours through one of Binghamton's finest homes.
University art museum featuring rotating contemporary and historical exhibitions with strong educational and regional programming.
Compact downtown core with theaters, shops, murals, and nightlife, ideal for walking and experiencing the city's revival.
Historic district centered on antique carousels, museums, and river access, popular with families and local history fans.
Large riverside park with trails, sports fields, and event space, offering broad views and an easy outdoor escape.
Binghamton's signature charcoal-grilled marinated chicken cubes on a skewer, traditionally soaked in a vinegar-based Italian-style marinade and served at summer cookouts.
A classic local sandwich of spiedie meat, usually chicken or pork, stuffed into soft Italian bread. It is the region's most famous street and festival food.
A tomato-based meat sauce with Greek roots, served over hot dogs. It is a longtime Binghamton staple at local stands and diners.
Well-regarded downtown restaurant serving refined American cuisine, cocktails, and a polished yet relaxed atmosphere suitable for a nicer night out.
Beloved casual spot known for classic spiedies, sandwiches, and local fast food. A must for tasting Binghamton's signature dish in an unfussy setting.
Historic hot dog stand famous for Coney-style dogs with Greek meat sauce. Quick, inexpensive, and deeply tied to local food tradition.
Moderate for a small US city: hotels and dining are usually cheaper than major metros, while transport often requires taxis or a car.
Tip 18-20% at restaurants, 15-20% for taxis, and $1-2 per drink or cafe order when service is good.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Binghamton, NY.
Find answers to the most common questions about traveling from Durham, NC to Binghamton, NY by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Binghamton, NY, this guide helps you travel smarter and with confidence.

Most Durham, NC to Binghamton, NY buses use the Durham, W Pettigrew St (Greyhound Bus Station) to Binghamton, Transportation Center station pair. Use this guide to compare Durham, NC and Binghamton, NY bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.