Travel Information
Compare bus and train for Siena to Zurich
Omio recommends booking the bus as it is the most popular option from Siena to Zurich among Omio's users. If you are prioritising price, take the train, with an average ticket price of $39 For those with little time, consider booking a train, which has an average total journey time of 7h 29m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a train costs an average of $39, while a bus costs an average of $63.
Distance: 310 miles (500 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$63 Average price | $39 Average price Cheapest | $233 Average price (fuel + tolls) |
12h 6m Average total duration 11h 36m Onboard + 30m Additional time* | 7h 29m Average total duration Fastest 6h 59m Onboard + 30m Additional time* | 6h 47m Average total duration (door-to-door) |
0.5 - 1.2kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Siena to Zurich
Compare the available ways to get from Siena to Zurich, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Siena to Zurich:
A train is $25 (€21) less than a bus for this route with tickets for a bus from Siena to Zurich costing on average $63 (€53).
Other travel options to Zurich take longer:
Bus takes on average 12h 6m.
Tickets start at around $63 (€53) compared to roughly $233 (€195) in fuel and tolls — a saving of about $170 (€143). The journey takes 11h 36m versus 6h 47m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Siena to Zurich
How to get from Siena to Zurich by train, bus or flight.
Our recommendation
The best way to travel from Siena to Zurich is by taking a bus because it’s the best combination of price and speed.
24941:05 AM10h10Siena, Stazione FS (Piazzale Carlo Rosselli)11:15 AMZürich, Sihlquai Bus Terminal (Carparkplatz Sihlquai)$381One-way0 transfers
Cheapest
24941:05 AM10h10Siena, Stazione FS (Piazzale Carlo Rosselli)11:15 AMZürich, Sihlquai Bus Terminal (Carparkplatz Sihlquai)$381One-way0 transfers
Fastest
Regionale 18278+
FRECCIAROSSA 9520+
EuroCity 168:48 AM7h39Siena station4:27 PMZurich HB$1931One-way2 transfers
Other options
Regionale 18200+
EuroCity 305:43 AM9h44Siena station3:27 PMZurich HB$1681One-way1 transfer
Regionale Veloce 4010+
Intercity 580+
EuroCity 166:25 AM10h02Siena station4:27 PMZurich HB$1691One-way2 transfers
Regionale 18224+
Intercity 590+
EuroCity 281:18 PM10h09Siena station11:27 PMZurich HB$1691One-way2 transfers
FlixBus · FlixBus9:20 AM12h00Siena, Stazione FS (Piazzale Carlo Rosselli)9:20 PMKloten, Zürich Flughafen (Bahnhof)$741One-way1 transfer
FlixBus+
U229887:00 AM14h20Siena, Stazione FS (Piazzale Carlo Rosselli)9:20 PMZurich Airport$1571One-way1 transfer
FlixBus+
U2298810:45 AM10h35Siena, Stazione FS (Piazzale Carlo Rosselli)9:20 PMZurich Airport$1671One-way1 transfer
FlixBus+
AZ71887:00 AM9h45Siena, Stazione FS (Piazzale Carlo Rosselli)4:45 PMZurich Airport$2131One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Siena to Zurich
Travel to Zurich easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Siena to Zurich.

This is compared to other travel options from Siena to Zurich:
A train is $25 (€21) less than a bus for this route with tickets for a bus from Siena to Zurich costing on average $63 (€53).
Other travel options to Zurich take longer:
Bus takes on average 12h 6m.
- Around 41 trains per day.
- Around 2 buses per day.
However, we recommend checking specific travel dates for your route between Siena and Zurich as scheduled services by bus and train can vary by season or day of the week.
- Trains mostly depart from Siena station and arrive in Zurich HB.
- Buses mostly depart from Siena, Stazione FS (Piazzale Carlo Rosselli) and arrive in Zürich, Sihlquai Bus Terminal (Carparkplatz Sihlquai).
- Travel with Trenitalia, Intercity to go to Zurich by train.
- Travel with Itabus, FlixBus to go to Zurich by bus.
- 1 direct buses per day with Itabus.
Travelling from Siena to Zurich: related information
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