Travel Information
Compare bus and train for Siena to Genoa
Omio recommends booking the bus as it is the most popular option from Siena to Genoa among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $26 For those with little time, consider booking a bus, which has an average total journey time of 4h 50m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.2kg. Average ticket prices depend on the travel mode: a bus costs an average of $26, while a train costs an average of $31.
Distance: 141 miles (227 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$26 Average price Cheapest | $31 Average price | $84 Average price (fuel + tolls) |
4h 50m Average total duration Fastest 4h 20m Onboard + 30m Additional time* | 5h 5m Average total duration 4h 35m Onboard + 30m Additional time* | 3h 13m Average total duration (door-to-door) |
0.2 - 0.6kg CO2 emissions | 0.1 - 0.2kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Siena to Genoa:
A bus is $4 less than a train for this route with tickets for a train from Siena to Genoa costing on average $31.
Other travel options to Genoa take longer:
Train takes on average 5h 5m.
Tickets start at around $26 compared to roughly $84 in fuel and tolls — a saving of about $58. The journey takes 4h 20m versus 3h 13m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Siena to Genoa
How to get from Siena to Genoa by train, bus or flight.
Our recommendation
The best way to travel from Siena to Genoa is by taking a bus because it’s the best combination of price and speed.
FlixBus10:40 AM4h25Siena, Stazione FS (Piazzale Carlo Rosselli)3:05 PMGenova, Via Fanti D'Italia$221One-way0 transfers
Cheapest
FlixBus10:40 AM4h25Siena, Stazione FS (Piazzale Carlo Rosselli)3:05 PMGenova, Via Fanti D'Italia$221One-way0 transfers
Fastest
Regionale 18238 · Regionale 18319+
FRECCIABIANCA 86307:18 PM4h09Siena station11:27 PMGenoa Piazza Principe$511One-way2 transfers
Other options
Regionale 18224 · Regionale 18373+
Intercity 6801:18 PM4h57Siena station6:15 PMGenoa Piazza Principe$371One-way2 transfers
Regionale 19044 · Regionale 18307+
Intercity 5184:41 PM4h53Siena station9:34 PMGenoa Piazza Principe$411One-way2 transfers
Regionale 18220 · Regionale 18367+
Intercity 67411:18 AM4h56Siena station4:14 PMGenoa Piazza Principe$411One-way2 transfers
FlixBus2:25 PM5h10Siena, Stazione FS (Piazzale Carlo Rosselli)7:35 PMGenova, Via Fanti D'Italia$231One-way0 transfers
FlixBus11:30 AM5h00Siena, Stazione FS (Piazzale Carlo Rosselli)4:30 PMGenova, Via Fanti D'Italia$231One-way0 transfers
FlixBus · FlixBus5:25 PM4h35Siena, Stazione FS (Piazzale Carlo Rosselli)10:00 PMGenova, Via Fanti D'Italia$241One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Siena to Genoa
Travel to Genoa easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Siena to Genoa.

This is compared to other travel options from Siena to Genoa:
A bus is $4 less than a train for this route with tickets for a train from Siena to Genoa costing on average $31.
Other travel options to Genoa take longer:
Train takes on average 5h 5m.
- Around 16 trains per day.
- Around 9 buses per day.
However, we recommend checking specific travel dates for your route between Siena and Genoa as scheduled services by bus and train can vary by season or day of the week.
- Trains mostly depart from Siena station and arrive in Genoa Piazza Principe.
- Buses mostly depart from Siena, Stazione FS (Piazzale Carlo Rosselli) and arrive in Genova, Via Fanti D'Italia.
- Travel with Frecciargento, Intercity, Frecciabianca, Frecciarossa, Regionale, Intercity Notte to go to Genoa by train.
- Travel with FlixBus, Itabus, BlaBlaCar to go to Genoa by bus.
- 4 direct buses per day with FlixBus, Itabus, BlaBlaCar.
Travelling from Siena to Genoa: related information
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