Travel Information
Compare bus, train, and flight for Zurich to Siena
Omio recommends booking the bus as it is the most popular option from Zurich to Siena among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $73 For those with little time, consider booking a train, which has an average total journey time of 7h 44m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $73, while a train costs an average of $166.
Distance: 310 miles (500 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$73 Average price Cheapest | $166 Average price | $231 Average price (fuel + tolls) |
12h 42m Average total duration 12h 12m Onboard + 30m Additional time* | 7h 44m Average total duration Fastest 7h 14m Onboard + 30m Additional time* | 7h 10m Average total duration (door-to-door) |
0.5 - 1.2kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Zurich to Siena
Compare the available ways to get from Zurich to Siena, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Zurich to Siena:
A bus is $93 (€79) less than a train for this route with tickets for a train from Zurich to Siena costing on average $166 (€139).
Other travel options to Siena take longer:
Bus takes on average 12h 42m.
Tickets start at around $73 (€61) compared to roughly $231 (€194) in fuel and tolls — a saving of about $158 (€133). The journey takes 12h 12m versus 7h 10m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Zurich to Siena
How to get from Zurich to Siena by train, bus or flight.
Our recommendation
The best way to travel from Zurich to Siena is by taking a bus because it’s the best combination of price and speed.
24956:25 PM 10h45 Zürich, Sihlquai Bus Terminal (Carparkplatz Sihlquai) 5:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) $39 1 One-way 0 transfers
Cheapest
24956:25 PM 10h45 Zürich, Sihlquai Bus Terminal (Carparkplatz Sihlquai) 5:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) $39 1 One-way 0 transfers
Fastest
EuroCity 123+
FRECCIAROSSA 9563+
Regionale 182333:33 PM 7h43 Zurich HB 11:16 PM Siena station $170 1 One-way 2 transfers
Other options
EuroCity 21+
Intercity 599+
Regionale 182331:33 PM 9h43 Zurich HB 11:16 PM Siena station $121 1 One-way 2 transfers
EuroCity 33+
Regionale 18423 · Regionale 1822910:33 AM 11h06 Zurich HB 9:39 PM Siena station $126 1 One-way 2 transfers
EuroCity 33+
FRECCIAROSSA 9543+
Regionale 1822310:33 AM 8h07 Zurich HB 6:40 PM Siena station $152 1 One-way 2 transfers
FlixBus · FlixBus8:45 AM 13h35 Kloten, Zürich Flughafen (Bahnhof) 10:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) $80 1 One-way 1 transfer
FlixBus · FlixBus · FlixBus3:50 PM 16h50 Kloten, Zürich Flughafen (Bahnhof) 8:40 AM Siena, Stazione FS (Piazzale Carlo Rosselli) $111 1 One-way 2 transfers
FlixBus · FlixBus · FlixBus11:05 AM 18h25 Kloten, Zürich Flughafen (Bahnhof) 5:30 AM Siena, Stazione FS (Piazzale Carlo Rosselli) $155 1 One-way 2 transfers
2970+
FlixBus8:15 AM 13h40 Zurich Airport 9:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) $92 1 One-way 1 transfer
2970+
FlixBus8:15 AM 8h45 Zurich Airport 5:00 PM Siena, Stazione FS (Piazzale Carlo Rosselli) $93 1 One-way 1 transfer
FlixBus+
U229708:15 AM 8h45 Zurich Airport 5:00 PM Siena, Stazione FS (Piazzale Carlo Rosselli) $100 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Zurich to Siena
Travel to Siena easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Zurich to Siena.

This is compared to other travel options from Zurich to Siena:
A bus is $93 (€79) less than a train for this route with tickets for a train from Zurich to Siena costing on average $166 (€139).
Other travel options to Siena take longer:
Bus takes on average 12h 42m.
- Around 9 trains per day.
- Around 3 buses per day.
However, we recommend checking specific travel dates for your route between Zurich and Siena as scheduled services by bus, train, and flight can vary by season or day of the week.
- Trains mostly depart from Zurich HB and arrive in Siena station.
- Buses mostly depart from Zürich, Sihlquai Bus Terminal (Carparkplatz Sihlquai) and arrive in Siena, Stazione FS (Piazzale Carlo Rosselli).
- Travel with Trenitalia, Intercity to go to Siena by train.
- Travel with FlixBus, Itabus, Marino Autolinee to go to Siena by bus.
- 1 direct buses per day with Itabus.
Travelling from Zurich to Siena: related information
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