Travel Information
Compare bus and flight for Frankfurt am Main to Santander
Omio recommends booking the flight as it is the most popular option from Frankfurt am Main to Santander among Omio's users. If you are prioritising price take the bus with prices starting from $63. For those with little time consider booking a flight which can get you there in 4h 0m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.2 - 3.0kg. The ticket price range depends on the travel mode: a bus costs an average of $63, and a flight costs an average of $180.
Distance: 746 miles (1202 km)
Compare flight with
Most popular Flight | Bus |
|---|---|
$696 Average price | $137 Average price Cheapest |
7h 0m Average total duration Fastest 4h 0m Onboard + 3h 0m Additional time* | 22h 5m Average total duration 21h 35m Onboard + 30m Additional time* |
3.6 - 7.2kg CO2 emissions | 1.2 - 3.0kg CO2 emissions Lowest |
![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Frankfurt am Main to Santander
How to get from Frankfurt am Main to Santander by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Santander is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus7:30 AM25h50Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)9:20 AMSantander, Estación de Autobuses$1691One-way1 transfer
Cheapest
FlixBus · FlixBus7:30 AM25h50Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)9:20 AMSantander, Estación de Autobuses$1691One-way1 transfer
Fastest
LH1114+
041931:20 PM10h08Frankfurt am Main Airport11:28 PMSantander station$9231One-way1 transfer
Other options
FlixBus · FlixBus · FlixBus5:55 AM27h25Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)9:20 AMSantander, Estación de Autobuses$1821One-way2 transfers
LH1116+
041437:45 AM11h26Frankfurt am Main Airport7:11 PMSantander station$5451One-way1 transfer
LH1116+
041937:45 AM15h43Frankfurt am Main Airport11:28 PMSantander station$5371One-way1 transfer
TP575 · TP1012+
041936:05 AM17h23Frankfurt am Main Airport11:28 PMSantander station$6721One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Frankfurt am Main to Santander
Travel to Santander easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Santander.

This is compared to other travel options from Frankfurt am Main to Santander:
A bus is $117 (€93) less than a flight for this route with tickets for a flight from Frankfurt am Main to Santander costing on average $180 (€144).
Other travel options to Santander take longer:
Bus takes on average 25h 5m.
- Around 3 flights per day.
- Around 3 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Santander as scheduled services by bus and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Santander Airport.
- Buses mostly depart from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) and arrive in Santander, Estación de Autobuses.
- Travel with Air Nostrum, Iberia to go to Santander by flight.
- Travel with FlixBus to go to Santander by bus.
Travelling from Frankfurt am Main to Santander: related information
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