Travel Information
Compare bus, flight, and train for Milan to San Salvo
Omio recommends booking the bus as it is the most popular option from Milan to San Salvo among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €68 For those with little time, consider booking a flight, which has an average total journey time of 3h 20m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.5kg. Average ticket prices depend on the travel mode: a bus costs an average of €68, while a flight costs an average of €101.
Distance: 363 miles (585 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
€68 Average price Cheapest | €92 Average price | €101 Average price | €170 Average price (fuel + tolls) |
10h 15m Average total duration 9h 45m Onboard + 30m Additional time* | 6h 37m Average total duration 6h 7m Onboard + 30m Additional time* | 3h 20m Average total duration Fastest 1h 20m Onboard + 2h 0m Additional time* | 6h 55m Average total duration (door-to-door) |
0.6 - 1.5kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Milan to San Salvo
Compare the available ways to get from Milan to San Salvo, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Milan to San Salvo:
A bus is €25 less than a train for this route with tickets for a train from Milan to San Salvo costing on average €92.
A bus is €34 less than a flight for this route with tickets for a flight from Milan to San Salvo costing on average €101.
Other travel options to San Salvo take longer:
Train takes on average 6h 37m.
Bus takes on average 10h 15m.
Tickets start at around €68 compared to roughly €170 in fuel and tolls — a saving of about €102. The journey takes 9h 45m versus 6h 55m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Milan to San Salvo
How to get from Milan to San Salvo by train, bus or flight.
Our recommendation
The best way to travel from Milan to San Salvo is by taking a bus because it’s the best combination of price and speed.

10:10 PM 8h39 Milan 6:49 AM San Salvo €61 1 One-way 0 transfers
Cheapest

10:10 PM 8h39 Milan 6:49 AM San Salvo €61 1 One-way 0 transfers
Fastest

10:10 PM 8h39 Milan 6:49 AM San Salvo €61 1 One-way 0 transfers
Other options

9:10 PM 8h39 Milan 5:49 AM San Salvo €93 1 One-way 0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Milan to San Salvo
Travel to San Salvo easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Milan to San Salvo.

This is compared to other travel options from Milan to San Salvo:
A bus is €25 less than a train for this route with tickets for a train from Milan to San Salvo costing on average €92.
A bus is €34 less than a flight for this route with tickets for a flight from Milan to San Salvo costing on average €101.
Other travel options to San Salvo take longer:
Train takes on average 6h 37m.
Bus takes on average 10h 15m.
- Around 10 trains per day.
- Around 8 buses per day.
- Around 3 flights per day.
However, we recommend checking specific travel dates for your route between Milan and San Salvo as scheduled services by bus, flight, and train can vary by season or day of the week.
- Flights mostly depart from Milan Malpensa Airport and arrive in Pescara Abruzzo Airport.
- Trains mostly depart from Milan Centrale and arrive in Vasto-San Salvo.
- Buses mostly depart from Milano, Autostazione Lampugnano and arrive in San Salvo Marina, Via Andea Doria (Terminal).
- Travel with Frecciarossa, Intercity, Intercity Notte, Regionale to go to San Salvo by train.
- Travel with FlixBus, Marino Autolinee to go to San Salvo by bus.
- Travel with Malta Air, Aeroitalia to go to San Salvo by flight.
- 3 direct trains per day with Frecciarossa, Intercity.
- 2 direct buses per day with FlixBus.
- 3 direct flights per day with Malta Air, Aeroitalia.
Travelling from Milan to San Salvo: related information
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