Travel Information
Compare bus, train, and flight for Heilbronn to Prague
Omio recommends booking the bus as it is the most popular option from Heilbronn to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a flight which can get you there in 1h 0m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $24, and a flight costs an average of $159.
Distance: 241 miles (389 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$46 Average price Cheapest | $140 Average price | $217 Average price |
5h 55m Average total duration 5h 25m Onboard + 30m Additional time* | 8h 11m Average total duration 7h 41m Onboard + 30m Additional time* | 4h 0m Average total duration Fastest 1h 0m Onboard + 3h 0m Additional time* |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.2 - 2.3kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Heilbronn to Prague
How to get from Heilbronn to Prague by train, bus or flight.
Our recommendation
The best way to travel from Heilbronn to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus8:55 AM6h30Heilbronn, Hbf (Central station)3:25 PMPraha, ÚAN Florenc$471One-way0 transfers
Cheapest
FlixBus · FlixBus3:30 PM7h25Heilbronn, Hbf (Central station)10:55 PMPraha, Na Knížecí$451One-way1 transfer
Fastest
DE44073:00 PM1h00Frankfurt am Main Airport4:00 PMPrague Vaclav Havel Airport$1861One-way0 transfers
Other options
19072 · ICE 589 · 3577+
3632:48 PM7h34Heilbronn Hbf10:22 PMPrague hlavní nádraží$991One-way3 transfers
19068 · ICE 587 · 3573+
36112:48 PM7h33Heilbronn Hbf8:21 PMPrague hlavní nádraží$1051One-way3 transfers
19064 · ICE 585 · 3569+
35910:48 AM7h33Heilbronn Hbf6:21 PMPrague hlavní nádraží$1171One-way3 transfers
FlixBus8:55 AM7h15Heilbronn, Hbf (Central station)4:10 PMPraha, Černý Most$471One-way0 transfers
FlixBus5:20 AM6h00Heilbronn, Hbf (Central station)11:20 AMPrague, Central Train Station$491One-way0 transfers
FlixBus5:20 AM6h10Heilbronn, Hbf (Central station)11:30 AMPraha, ÚAN Florenc$491One-way0 transfers
DE440910:00 AM1h00Frankfurt am Main Airport11:00 AMPrague Vaclav Havel Airport$2011One-way0 transfers
DE44118:20 PM1h00Frankfurt am Main Airport9:20 PMPrague Vaclav Havel Airport$1861One-way0 transfers
LO372 · LO52110:50 AM6h30Stuttgart Airport5:20 PMPrague Vaclav Havel Airport$2371One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Heilbronn to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Heilbronn to Prague.

This is compared to other travel options from Heilbronn to Prague:
A bus is $34 (€27) less than a train for this route with tickets for a train from Heilbronn to Prague costing on average $58 (€46).
A bus is $135 (€108) less than a flight for this route with tickets for a flight from Heilbronn to Prague costing on average $159 (€127).
Other travel options to Prague take longer:
Bus takes on average 6h 20m.
Train takes on average 7h 15m.
- Around 57 flights per day.
- Around 8 buses per day.
- Around 7 trains per day.
However, we recommend checking specific travel dates for your route between Heilbronn and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Heilbronn Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Heilbronn, Hbf (Central station) and arrive in Praha, ÚAN Florenc.
- Travel with Deutsche Bahn, alex-Länderbahn und Vogtlandbahn-GmbH, Go Ahead BW to go to Prague by train.
- Travel with FlixBus, BlaBlaCar, Bus (Region) to go to Prague by bus.
- Travel with Lufthansa to go to Prague by flight.
- 5 direct buses per day with FlixBus, BlaBlaCar.
- 7 direct flights per day with Lufthansa.
Travelling from Heilbronn to Prague: related information
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