Travel Information
Compare bus, train, and flight for Prague to Heilbronn
Omio recommends booking the bus as it is the most popular option from Prague to Heilbronn among Omio's users. If you are prioritising price, take the bus, with an average ticket price of Kč 986 For those with little time, consider booking a flight, which has an average total journey time of 4h 43m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of Kč 986, while a flight costs an average of Kč 8,625.
Distance: 241 miles (389 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
Kč 986 Average price Cheapest | Kč 3,428 Average price | Kč 8,625 Average price | Kč 2,100 Average price (fuel + tolls) |
6h 38m Average total duration 6h 8m Onboard + 30m Additional time* | 8h 3m Average total duration 7h 33m Onboard + 30m Additional time* | 4h 43m Average total duration Fastest 2h 43m Onboard + 2h 0m Additional time* | 4h 24m Average total duration (door-to-door) |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.2 - 2.3kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Prague to Heilbronn
Compare the available ways to get from Prague to Heilbronn, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Prague to Heilbronn:
A bus is Kč 2,442 less than a train for this route with tickets for a train from Prague to Heilbronn costing on average Kč 3,428.
A bus is Kč 7,640 less than a flight for this route with tickets for a flight from Prague to Heilbronn costing on average Kč 8,625.
Other travel options to Heilbronn take longer:
Bus takes on average 6h 38m.
Train takes on average 8h 3m.
Tickets start at around Kč 986 compared to roughly Kč 2,100 in fuel and tolls — a saving of about Kč 1,114. The journey takes 6h 8m versus 4h 24m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Prague to Heilbronn
How to get from Prague to Heilbronn by train, bus or flight.
Our recommendation
The best way to travel from Prague to Heilbronn is by taking a train because it’s the best combination of price and speed.
RJ 512 · 5286 · IC 2068 · 2341210:35 AM 7h17 Prague hlavní nádraží 5:52 PM Heilbronn Hbf Kč 859 1 One-way 3 transfers
Cheapest
RJ 512 · 5286 · IC 2068 · 2341210:35 AM 7h17 Prague hlavní nádraží 5:52 PM Heilbronn Hbf Kč 859 1 One-way 3 transfers
Fastest
DE44818:00 AM 1h05 Prague Vaclav Havel Airport 9:05 AM Frankfurt am Main Airport Kč 3,738 1 One-way 0 transfers
Other options
IC 564 · 5284 · IC 2160 · 234108:35 AM 7h17 Prague hlavní nádraží 3:52 PM Heilbronn Hbf Kč 859 1 One-way 3 transfers
IC 562 · 5288 · IC 2066 · 2341412:35 PM 7h17 Prague hlavní nádraží 7:52 PM Heilbronn Hbf Kč 859 1 One-way 3 transfers
EX 352 · 3580 · ICE 582 · 190873:35 PM 7h36 Prague hlavní nádraží 11:11 PM Heilbronn Hbf Kč 859 1 One-way 3 transfers
FlixBus6:40 AM 6h25 Praha, ÚAN Florenc 1:05 PM Heilbronn, Hbf (Central station) Kč 885 1 One-way 0 transfers
FlixBus · FlixBus3:05 PM 6h25 Praha, Zličín 9:30 PM Heilbronn, Hbf (Central station) Kč 1,080 1 One-way 1 transfer
FlixBus3:10 PM 6h20 Praha, ÚAN Florenc 9:30 PM Heilbronn, Hbf (Central station) Kč 1,561 1 One-way 0 transfers
DE448311:45 AM 1h10 Prague Vaclav Havel Airport 12:55 PM Frankfurt am Main Airport Kč 3,738 1 One-way 0 transfers
DE44855:05 PM 1h10 Prague Vaclav Havel Airport 6:15 PM Frankfurt am Main Airport Kč 4,545 1 One-way 0 transfers
LO524 · LO3779:35 AM 6h20 Prague Vaclav Havel Airport 3:55 PM Frankfurt am Main Airport Kč 5,906 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Prague to Heilbronn
Travel to Heilbronn easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Heilbronn.

This is compared to other travel options from Prague to Heilbronn:
A bus is Kč 2,442 less than a train for this route with tickets for a train from Prague to Heilbronn costing on average Kč 3,428.
A bus is Kč 7,640 less than a flight for this route with tickets for a flight from Prague to Heilbronn costing on average Kč 8,625.
Other travel options to Heilbronn take longer:
Bus takes on average 6h 38m.
Train takes on average 8h 3m.
- Around 70 flights per day.
- Around 9 buses per day.
- Around 8 trains per day.
However, we recommend checking specific travel dates for your route between Prague and Heilbronn as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Heilbronn Hbf.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Heilbronn, Hbf (Central station).
- Travel with Deutsche Bahn, České dráhy to go to Heilbronn by train.
- Travel with FlixBus, AMI-Tour to go to Heilbronn by bus.
- Travel with Lufthansa, Lot Polish Airlines, KLM, Swiss, Austrian Airlines, Turkish Airlines, Condor Flugdienst, British Airways, Air Baltic, Eurowings, Brussels Airlines, Air Dolomiti, KLM Cityhopper, Lufthansa Cityline, Qatar Airways, Helvetic Airways, CitizenPlane, Edelweiss Air to go to Heilbronn by flight.
- 6 direct buses per day with FlixBus, AMI-Tour.
- 8 direct flights per day with Lufthansa, Condor Flugdienst, Air Dolomiti.
Travelling from Prague to Heilbronn: related information
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