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The cheapest and fastest trains from Venice Mestre to Siena
Showing times and prices for Nov 07
Cheapest price
$42
Average price
$48
Fastest journey
5 h 45 m
Average duration
7 h 9 m
Trains per day
4
Distance
251 km
Cheap tickets
The best way to find a cheap train ticket from Venice Mestre to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Venice Mestre to Siena will cost around $48 if you buy it on the day, but the cheapest tickets can be found for only $42.
Fast trains
Of the 4 trains that leave Venice Mestre for Siena on Fri, Nov 07, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Nov 07 the direct trains cover the 251 km distance in an average of 7 h 9 m but if you time it right, some trains will get you there in just 5 h 45 m .
On Fri, Nov 07 the slowest trains will take 9 h 11 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
11:26AM6h40
Venice Mestre06:06PMSiena
$421One-way
0 transfers
11:53AM5h45
Venice Mestre05:38PMSiena
$451One-way
0 transfers
07:34AM7h00
Venice Mestre02:34PMSiena
$491One-way
0 transfers
08:17PM9h11
Venice Mestre05:28AMSiena
$571One-way
0 transfers
11:53AM5h45
Venice Mestre05:38PMSiena
$451One-way
0 transfers
11:26AM6h40
Venice Mestre06:06PMSiena
$421One-way
0 transfers
07:34AM7h00
Venice Mestre02:34PMSiena
$491One-way
0 transfers
08:17PM9h11
Venice Mestre05:28AMSiena
$571One-way
0 transfers
Travel Information
Compare bus and train for Venice Mestre to Siena
Omio recommends booking the bus as it is the most popular option from Venice Mestre to Siena among Omio's users. If you are prioritising price take the bus with prices starting from €18. For those with little time consider booking a train which can get you there in 3h 51m. The ticket price range depends on the travel mode: a bus costs an average of €18, and a train costs an average of €22.
Distance: 155 miles (251 km)
Compare train with
| Train | Most popular Bus |
|---|---|
€42 Average price | €29 Average price Cheapest |
4h 21m Average total duration Fastest 3h 51m Onboard + 30m Additional time* | 4h 59m Average total duration 4h 29m Onboard + 30m Additional time* |
 Most popular train company |  Most popular bus company |
Direct Options | Direct Options |
Live departures
Venice Mestre to Siena train times
The table below shows live departures for Venice Mestre to Siena trains for today, Thursday, November 6. You can also manually refresh the results below to see updated train journeys.
Last updated at 1:47 AM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 3:53 AM Venice Mestre | 6h45 | 10:38 AM Siena | 0 transfersDirect | |
| 8:17 PM Venice Mestre | 9h11 | 5:28 AM Siena | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Venice Mestre to Siena by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Fri
Nov 07
Nov 07
Sat
Nov 08
Nov 08
Sun
Nov 09
Nov 09
Mon
Nov 10
Nov 10
Tue
Nov 11
Nov 11
Wed
Nov 12
Nov 12
Thu
Nov 13
Nov 13
Journey information
Overview: Train from Venice Mestre to Siena
ItalyItaly
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $23 (€18)
Distance 155 miles (251 km) |
Average train duration 3h 51m |
Cheapest ticket price $27 (€22) |
Trains per day 16 |
Fastest train 4h 0m |
First train 03:38 |
Last train 20:17 |
Key Takeaways
Train Ticket Prices
- Budget Options: Train tickets from Venice Mestre to Siena start from as low as $27 (€22) if booked well in advance.
- Standard Fares: Typically, trains cost $51 (€42) depending on the train type and class.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $23 (€18)
Train companies: Frecciarossa, Italo, Regionale from Venice Mestre to Siena trainsFrecciarossa, Italo, Regionale trains will get you between Venice Mestre and Siena from $23 (€18). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
3h 58m
Cheapest Price
$40 (€33)
Frecciarossa frequency
11 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Italo
About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
6h 47m
Cheapest Price
$35 (€29)
Regionale frequency
2 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
FAQs: Trains from Venice Mestre to Siena
Find answers to the most common questions about traveling from Venice Mestre to Siena by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.
The train journey from Venezia Mestre to Siena offers scenic views, especially as it passes through Tuscany, known for its rolling hills, vineyards, and charming medieval towns.
A day trip from Venezia Mestre to Siena is not feasible as the journey takes 4h 0m, and the frequency is 16 per day for trains over a distance of 155 miles (251 km).
To fully experience Siena, including its historic sites, museums, and local cuisine, plan to spend 2 to 3 days.
In Siena, you can visit Torre del Mangia for panoramic views, explore religious art at Museo dell'Opera del Duomo, and relax at Fortezza Medicea. Enjoy Italian wines at Enoteca Italiana, or take a cooking class to learn traditional Tuscan dishes. Don't miss the Piazza del Campo with its historic ambiance or the magnificent Siena Cathedral. Also, check out the Palazzo Pubblico, Basilica of San Domenico, and Santa Maria della Scala for a rich cultural experience.
Train ticket prices from Venice Mestre to Siena can vary. The cheapest ticket starts at $27 (€22), while the average price is around $51 (€42).
The train from Venice Mestre to Siena takes 4h 0m and runs 16 per day.
The distance by train from Venice Mestre to Siena is 155 miles (251 km).
The cheapest way to get from Venice Mestre to Siena is by bus, with a cost of around $23 (€18).
The last train from Venice Mestre to Siena leaves at 8:17 PM.
The first train from Venice Mestre to Siena leaves at 3:38 AM.
Yes, there is a high-speed train from Venice Mestre to Siena.
There is no direct train service currently available from Venice Mestre to Siena.
Yes, you can take the train from Venice Mestre to Siena.
Unfortunately, there is no night train available from Venice Mestre to Siena.
popular train stations
Popular train stations from Venice Mestre to Siena
Venice
Siena
The major train station for departures in Venice is Venezia Mestre. Find all the information you need to know about services, amenities and connections at Venezia Mestre for your trip from Venice to Siena.
Amenities at train station
Lockers
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Ticket Office
Bike Parking
Bike Rental
Car Rental
Information Deskinformation
Ticket Office Hours
- Mon - Sun: 05:50 - 20:30
Distance to city center
8 kmLockers
- Provided by KiPoint and located on the ground floor.
Dining
- McDonald’s
- Chock Full O'Nuts
- Puro Gusto
- Juice Bar
- Rossosapore
Accessibility
- Full accessibility facilities, including toilets, ramps, wheelchairs, elevators and a mobility assistance center.
Hotel
- Best Western Hotel Tritone
- The Plaza Hotel
- Hotel Villa Constanza
Ticket Office
- Mon - Sun: 05:50 - 20:30
Information Desk
- Located in the main concourse.
Public transit options for Venezia Mestre
- Bus lines: 2, 3, 10, 15, 18, 25a, 31, 31H, 32, 32H, 33H, 34H, 43, 53, 86, N1, 8AE
- Train lines: FR, FA, FB, EC, RJ, IC, EN, ICN, R, Italo
The major train station for arrivals in Siena is Siena. Find all the information you need to know about services, amenities and connections at Siena for your journey to Siena from Venice.
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotel
Lost and Found OfficeTicket OfficeBike ParkingBike RentalInformation Desk
Luggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 8:00 PM Monday - Sunday
Distance to city center
1 km
Number of platforms
5Wifi
- Free
Parking
- Parking is available near the station, open 24/7.
Dining
- Ristorante Il Vinaio
- Osteria Le Logge
Taxis
- Outside the main entrance.
Accessibility
- Elevators, ramps.
WC
- €1
Hotel
- Hotel Italia
- NH Siena
- Hotel Minerva
Lost and Found Office
- Located near the main entrance
Information Desk
- Located near the main entrance
Luggage Carts
- Free
Station Plan
- The station has a single-level layout with platforms accessible from the main hall.
Public transit options for Siena
- Bus: Several local and regional lines available
- Taxi: Available outside the station
More options for your journey from Venice Mestre to Siena
Here are some other resources that might have the information you need
Most popular trains to and from Siena and Venice Mestre
Most popular train connections to Siena
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