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The cheapest and fastest trains from Venice Mestre to Siena
Showing times and prices for May 12
Cheapest price
$39
Average price
$54
Fastest journey
3 h 58 m
Average duration
3 h 59 m
Trains per day
55
Distance
251 km
Cheap tickets
The best way to find a cheap train ticket from Venice Mestre to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Venice Mestre to Siena will cost around $54 if you buy it on the day, but the cheapest tickets can be found for only $39.
Fast trains
It's difficult to get from Venice Mestre to Siena without transferring at least once.
Intercity 584+
Regionale 182231:05 PM5h35Venice Mestre6:40 PMSiena station$391One-way1 transfer- Intercity 594+Regionale 182273:34 PM5h06Venice Mestre8:40 PMSiena station$391One-way1 transfer
- Intercity 594+Regionale Veloce 4047 · Regionale 190533:34 PM4h42Venice Mestre8:16 PMSiena station$391One-way2 transfers
- Intercity 584+Regionale Veloce 4043 · Regionale 188511:05 PM5h10Venice Mestre6:15 PMSiena station$391One-way2 transfers
- Regionale Veloce 3985+Intercity 599+Regionale 182335:53 PM5h23Venice Mestre11:16 PMSiena station$441One-way2 transfers
FRECCIAROSSA 9409+Regionale 182098:40 AM3h58Venice Mestre12:38 PMSiena station$681One-way1 transfer- FRECCIAROSSA 9415+Regionale 1821711:38 AM3h59Venice Mestre3:37 PMSiena station$731One-way1 transfer
- FRECCIAROSSA 9427+Regionale 182253:38 PM4h00Venice Mestre7:38 PMSiena station$601One-way1 transfer
- FRECCIAROSSA 9401+Regionale 182035:38 AM4h00Venice Mestre9:38 AMSiena station$531One-way1 transfer
- FRECCIAROSSA 9421+Regionale 182211:38 PM4h00Venice Mestre5:38 PMSiena station$571One-way1 transfer
Travel Information
Compare bus and train for Venice Mestre to Siena
Omio recommends booking the bus as it is the most popular option from Venice Mestre to Siena among Omio's users. If you are prioritising price take the bus with prices starting from $21. For those with little time consider booking a train which can get you there in 4h 6m. The ticket price range depends on the travel mode: a bus costs an average of $21, and a train costs an average of $25.
Distance: 155 miles (251 km)
Compare train with
| Train | Most popular Bus | Driving |
|---|---|---|
$44 Average price | $31 Average price Cheapest | $92 Average price (fuel + tolls) |
4h 36m Average total duration Fastest 4h 6m Onboard + 30m Additional time* | 4h 58m Average total duration 4h 28m Onboard + 30m Additional time* | 3h 7m Average total duration (door-to-door) |
Most popular train company |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Venice Mestre to Siena is a bus with an average price of $31 (€25).
This is compared to other travel options from Venice Mestre to Siena:
A bus is $13 (€10) less than a train for this route with tickets for a train from Venice Mestre to Siena costing on average $44 (€35).
The fastest way to travel from Venice Mestre to Siena is by train with an average journey time of 4h 6m.
Other travel options to Siena take longer:
Bus takes on average 4h 28m.
It's helpful to compare your options as there are 2 ways to travel between Venice Mestre and Siena including taking a bus and train.
We recommend using the bus as it is the most popular way to get from Venice Mestre to Siena among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around {cheapestPrice} compared to roughly {drivingPriceInCents} in fuel and tolls — a saving of about {savingsAmount}. The journey takes {durationInMinutes} versus {drivingDurationInMinutes} by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Italo.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Venice Mestre to Siena train times
The table below shows live departures for Venice Mestre to Siena trains for today, Monday, May 11. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 12:05 PM Venice Mestre | 5h10 | 5:15 PM Siena | 0 transfersDirect | |
| 12:53 PM Venice Mestre | 5h45 | 6:38 PM Siena | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Venice Mestre to Siena by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Venice Mestre to Siena trains with Omio?
Frecciarossa as well as Italo, Regionale, Intercity and more offer trains services from Venice Mestre to Siena.
Omio is an official ticket reseller for all your travel options from Venice Mestre to Siena.
Why book with Omio vs Frecciarossa?
- Compare with other providers: On Omio, you can not only buy tickets for Frecciarossa, but also compare tickets for the likes of Italo, Regionale or Intercity to find the best option for your trip from Venice Mestre to Siena.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Frecciarossa with all available travel options, which are bus and train to ensure you get the best deal for traveling from Venice Mestre to Siena.
Why book with Omio over Raileurope?
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Venice Mestre to Siena.
Journey information
Overview: Train from Venice Mestre to Siena
ItalyItaly
Trains from Venice Mestre to Siena run on average 15 times per day, taking around 4h 6m. Cheap train tickets for this journey start at $25 (€20) but you can travel from only $21 (€17) by bus.
The earliest train runs at 07:34, the last at 15:38. The fastest train covers the 155 miles (251 km) distance in 4h 1m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $21 (€17)
Distance 155 miles (251 km) |
Average train duration 4h 6m |
Cheapest ticket price $25 (€20) |
Trains per day 15 |
Fastest train 4h 1m |
First train 7:34 AM |
Last train 3:38 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Sat |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $21 (€17)
Train companies: Frecciarossa, Italo, Regionale, Intercity from Venice Mestre to Siena trainsFrecciarossa, Italo, Regionale, Intercity trains will get you between Venice Mestre and Siena from $21 (€17). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
4h 1m
Cheapest Price
$53 (€42)
Frecciarossa frequency
11 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Italo
About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Italo frequency
6 a day
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
6h 47m
Cheapest Price
$36 (€29)
Regionale frequency
2 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
Intercity
About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Duration
4h 42m
Cheapest Price
$25 (€20)
Intercity frequency
3 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone
FAQs: Trains from Venice Mestre to Siena
Find answers to the most common questions about traveling from Venice Mestre to Siena by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.
Train ticket prices from Venice Mestre to Siena can vary. The cheapest ticket starts at $25 (€20), while the average price is around $44 (€35).
The train from Venice Mestre to Siena takes 4h 1m and runs 15 per day.
The distance by train from Venice Mestre to Siena is 155 miles (251 km).
The first train from Venice Mestre to Siena leaves at 7:34 AM.
The last train from Venice Mestre to Siena leaves at 3:38 PM.
Yes, there is a high-speed train from Venice Mestre to Siena.
Yes, there is a direct train from Venice Mestre to Siena. This service operates 0 times per day, provided by Italo.
Unfortunately, there is no night train available from Venice Mestre to Siena.
The cheapest way to get from Venice Mestre to Siena is by bus, with a cost of around $21 (€17).
The train journey from Venezia Mestre to Siena offers scenic views, especially as it passes through Tuscany, known for its rolling hills, vineyards, and charming medieval towns.
A day trip from Venezia Mestre to Siena is not feasible as the journey takes 4h 1m, and the frequency is 16 per day for trains over a distance of 155 miles (251 km).
In Siena, you can visit Torre del Mangia for panoramic views, explore religious art at Museo dell'Opera del Duomo, and relax at Fortezza Medicea. Enjoy Italian wines at Enoteca Italiana, or take a cooking class to learn traditional Tuscan dishes. Don't miss the Piazza del Campo with its historic ambiance or the magnificent Siena Cathedral. Also, check out the Palazzo Pubblico, Basilica of San Domenico, and Santa Maria della Scala for a rich cultural experience.
To fully experience Siena, including its historic sites, museums, and local cuisine, plan to spend 2 to 3 days.
Yes, you can take the train from Venice Mestre to Siena.
Since both Venice Mestre and Siena are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Siena include Florence, San Gimignano, Montepulciano, Poggibonsi, Livorno.
We recommend using the bus as it is the most popular way to get from Venice Mestre to Siena among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Siena, travelers should be cautious of pickpocketing, especially in crowded areas like Piazza del Campo and on public transportation. Common scams include overpriced taxi rides and unofficial ticket sellers near popular attractions. Staying aware of surroundings and using authorized services helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Venice Mestre to Siena
Venice
Siena
The major train station for departures in Venice is Venezia Mestre. Find all the information you need to know about services, amenities and connections at Venezia Mestre for your trip from Venice to Siena.
Amenities at train station
Lockers
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Ticket Office
Bike Parking
Bike Rental
Car Rental
Information Deskinformation
Ticket Office Hours
- Mon - Sun: 05:50 - 20:30
Distance to city center
8 kmLockers
- Provided by KiPoint and located on the ground floor.
Dining
- McDonald’s
- Chock Full O'Nuts
- Puro Gusto
- Juice Bar
- Rossosapore
Accessibility
- Full accessibility facilities, including toilets, ramps, wheelchairs, elevators and a mobility assistance center.
Hotel
- Best Western Hotel Tritone
- The Plaza Hotel
- Hotel Villa Constanza
Ticket Office
- Mon - Sun: 05:50 - 20:30
Information Desk
- Located in the main concourse.
Public transit options for Venezia Mestre
- Bus lines: 2, 3, 10, 15, 18, 25a, 31, 31H, 32, 32H, 33H, 34H, 43, 53, 86, N1, 8AE
- Train lines: FR, FA, FB, EC, RJ, IC, EN, ICN, R, Italo
The major train station for arrivals in Siena is Siena. Find all the information you need to know about services, amenities and connections at Siena for your journey to Siena from Venice.
Amenities at train station
WifiLockersParkingDiningATMTaxisAccessibilityWCHotel
Lost and Found OfficeTicket OfficeBike ParkingBike RentalInformation Desk
Luggage Cartsinformation
Ticket Office Hours
- 6:00 AM - 8:00 PM Monday - Sunday
Distance to city center
1 km
Number of platforms
5Wifi
- Free
Parking
- Parking is available near the station, open 24/7.
Dining
- Ristorante Il Vinaio
- Osteria Le Logge
Taxis
- Outside the main entrance.
Accessibility
- Elevators, ramps.
WC
- €1
Hotel
- Hotel Italia
- NH Siena
- Hotel Minerva
Lost and Found Office
- Located near the main entrance
Information Desk
- Located near the main entrance
Luggage Carts
- Free
Station Plan
- The station has a single-level layout with platforms accessible from the main hall.
Public transit options for Siena
- Bus: Several local and regional lines available
- Taxi: Available outside the station
More options for your journey from Venice Mestre to Siena
Here are some other resources that might have the information you need
Most popular trains to and from Siena and Venice Mestre
Most popular train connections to Siena
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