The cheapest and fastest trains from Siena to Venice Mestre
Cheapest price
$37
Average price
$58
Fastest journey
3 h 58 m
Average duration
4 h 4 m
Trains per day
21
Distance
251 km
The best way to find a cheap train ticket from Siena to Venice Mestre is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Siena to Venice Mestre will cost around $58 if you buy it on the day, but the cheapest tickets can be found for only $37.
It's difficult to get from Siena to Venice Mestre without transferring at least once.
Regionale 18208 · Regionale 17816 · Regionale Veloce 3994
Regionale 18232+
Intercity 592
Regionale 19044 · Regionale 18312+
Intercity 592
Regionale 18220+
Intercity 588
Regionale 18234+
Intercity 596+
Regionale Veloce 3992
Regionale Veloce 4010+
FRECCIAROSSA 1000 9404
Regionale 18238+
FRECCIAROSSA 1000 9434
Regionale 18226+
FRECCIAROSSA 1000 9423
Regionale 18222+
FRECCIAROSSA 1000 9420
Regionale 18228+
FRECCIAROSSA 9426Travel Information
Compare bus and train for Siena to Venice Mestre
Omio recommends booking the train as it is the most popular option from Siena to Venice Mestre among Omio's users. If you are prioritising price take the bus with prices starting from €20. For those with little time consider booking a train which can get you there in 3h 51m. The ticket price range depends on the travel mode: a bus costs an average of €20, and a train costs an average of €27.
Distance: 155 miles (251 km)
Compare train with
Most popular Train | Bus |
|---|---|
€41 Average price | €31 Average price Cheapest |
4h 21m Average total duration Fastest 3h 51m Onboard + 30m Additional time* | 5h 6m Average total duration 4h 36m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Siena to Venice Mestre train times
The table below shows live departures for Siena to Venice Mestre trains for today, Sunday, February 8. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:02 PM Siena | 10h06 | 4:08 AM Venice Mestre | 0 transfersDirect | |
| Monday, February 9 | |||||
Regionale 19030 · Regionale 18254+ FRECCIAROSSA 1000 9400 | 4:00 AM Siena station | 4h23 | 8:23 AM Venice Mestre | 2 transfers | |
Regionale Veloce 4010+ Intercity 580+ Regionale Veloce 3972 | 5:25 AM Siena station | 5h42 | 11:07 AM Venice Mestre | 2 transfers | |
Regionale Veloce 4010+ FRECCIAROSSA 1000 9404 | 5:25 AM Siena station | 3h58 | 9:23 AM Venice Mestre | 1 transfer | |
Regionale 18208 · Regionale 17816 · Regionale Veloce 3994 | 5:36 AM Siena station | 6h31 | 12:07 PM Venice Mestre | 2 transfers | |
Regionale 18212+ FRECCIAROSSA 1000 9406 | 6:02 AM Siena station | 4h21 | 10:23 AM Venice Mestre | 1 transfer | |
Regionale 18214+ FRECCIAROSSA 9490 | 7:18 AM Siena station | 4h05 | 11:23 AM Venice Mestre | 1 transfer | |
Regionale 18218+ FRECCIAROSSA 9414 | 8:18 AM Siena station | 4h05 | 12:23 PM Venice Mestre | 1 transfer | |
Regionale 18220+ Intercity 588 | 10:18 AM Siena station | 4h58 | 3:16 PM Venice Mestre | 1 transfer | |
Regionale 18220+ FRECCIAROSSA 1000 8418 | 10:18 AM Siena station | 4h05 | 2:23 PM Venice Mestre | 1 transfer | |
Regionale 18222+ FRECCIAROSSA 1000 9420 | 11:18 AM Siena station | 4h05 | 3:23 PM Venice Mestre | 1 transfer | |
Regionale 18224+ Intercity 590+ Regionale Veloce 3986 | 12:18 PM Siena station | 5h49 | 6:07 PM Venice Mestre | 2 transfers | |
Regionale 18224+ FRECCIAROSSA 9422 | 12:18 PM Siena station | 4h05 | 4:23 PM Venice Mestre | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Siena to Venice Mestre by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 09
Feb 10
Feb 11
Feb 12
Feb 13
Feb 14
Feb 15
Why should you book Siena to Venice Mestre trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa or Intercity to find the best option for your trip from Siena to Venice Mestre.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are bus and train to ensure you get the best deal for traveling from Siena to Venice Mestre.
Why book with Omio over Raileurope?
- Official reseller: Italo tickets can only be bought on Omio or Italo's website as Omio is the only official third party seller for Italo tickets. Raileurope do not sell Italo tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Siena to Venice Mestre.
Journey information
Overview: Train from Siena to Venice Mestre
Trains from Siena to Venice Mestre run on average 14 times per day, taking around 3h 51m. Cheap train tickets for this journey start at $34 (€27) but you can travel from only $25 (€20) by bus.
The earliest train runs at 05:36, the last at 19:02. The fastest train covers the 155 miles (251 km) distance in 2h 3m.
Distance 155 miles (251 km) |
Average train duration 3h 51m |
Cheapest ticket price $34 (€27) |
Trains per day 14 |
Fastest train 2h 3m |
First train 05:36 |
Last train 19:02 |
Train companies: Italo, Frecciarossa, Intercity from Siena to Venice Mestre trainsItalo, Frecciarossa, Intercity trains will get you between Siena and Venice Mestre from $25 (€20). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Intercity
FAQs: Trains from Siena to Venice Mestre
Find answers to the most common questions about traveling from Siena to Venice Mestre by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Venice Mestre, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Siena to Venice Mestre
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available near the station, open 24/7.
- Ristorante Il Vinaio
- Osteria Le Logge
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Italia
- NH Siena
- Hotel Minerva
- Located near the main entrance
- Located near the main entrance
- Free
- The station has a single-level layout with platforms accessible from the main hall.
- Bus: Several local and regional lines available
- Taxi: Available outside the station
- Mon - Sun: 05:50 - 20:30
- Provided by KiPoint and located on the ground floor.
- McDonald’s
- Chock Full O'Nuts
- Puro Gusto
- Juice Bar
- Rossosapore
- Full accessibility facilities, including toilets, ramps, wheelchairs, elevators and a mobility assistance center.
- Best Western Hotel Tritone
- The Plaza Hotel
- Hotel Villa Constanza
- Mon - Sun: 05:50 - 20:30
- Located in the main concourse.
- Bus lines: 2, 3, 10, 15, 18, 25a, 31, 31H, 32, 32H, 33H, 34H, 43, 53, 86, N1, 8AE
- Train lines: FR, FA, FB, EC, RJ, IC, EN, ICN, R, Italo
Most popular train connections from Siena
More options for your journey from Siena to Venice Mestre
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