- Must visit
Pinacoteca di Brera
One of Milan’s premier art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Cheapest price
$20
Average price
$27
Fastest journey
2 h 18 m
Average duration
2 h 30 m
Trains per day
11
Distance
128 km
The best way to find a cheap train ticket from Santa Margherita Ligure-Portofino to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santa Margherita Ligure-Portofino to Milan Centrale will cost around $27 if you buy it on the day, but the cheapest tickets can be found for only $20.
Of the 11 trains that leave Santa Margherita Ligure-Portofino for Milan Centrale on Sun, Jun 21, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct trains cover the 128 km distance in an average of 2 h 30 m but if you time it right, some trains will get you there in just 2 h 18 m .
On Sun, Jun 21 the slowest trains will take 2 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale Veloce 3261 · Regionale Veloce 3028
Regionale Veloce 3016
Regionale 12452 · Regionale Veloce 3047
Regionale 12458 · Regionale Veloce 2146 · Regionale Veloce 3047
Regionale 12316 · Regionale Veloce 3019
Intercity 652
Intercity 658
Regionale 12216+
Intercity 662
Regionale Veloce 3261 · Regionale Veloce 3028
Regionale Veloce 3016Omio recommends booking the train as it is the most popular option from Santa Margherita Ligure-Portofino to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $6. For those with little time consider booking a bus which can get you there in 1h 48m. The ticket price range depends on the travel mode: a bus costs an average of $6, and a train costs an average of $19.
Distance: 79 miles (128 km)
Most popular Train | Bus | Driving |
|---|---|---|
$20 Average price | $10 Average price Cheapest | $51 Average price (fuel + tolls) |
3h 1m Average total duration 2h 31m Onboard + 30m Additional time* | 2h 18m Average total duration Fastest 1h 48m Onboard + 30m Additional time* | 2h 11m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Santa Margherita Ligure-Portofino to Milan Centrale:
A bus is $11 (€9) less than a train for this route with tickets for a train from Santa Margherita Ligure-Portofino to Milan Centrale costing on average $20 (€17).
Other travel options to Milan Centrale take longer:
Train takes on average 2h 31m.
Tickets start at around {cheapestPrice} compared to roughly {drivingPriceInCents} in fuel and tolls — a saving of about {savingsAmount}. The journey takes {durationInMinutes} versus {drivingDurationInMinutes} by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Direct services run with Intercity, Regionale.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Santa Margherita Ligure-Portofino to Milan Centrale trains for today, Saturday, June 20. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Intercity 674 | 3:46 PM Santa Margherita Ligure-Portofino | 2h19 | 6:05 PM Milan Centrale | 0 transfersDirect | |
Regionale 12414+ Intercity 635 | 3:55 PM Santa Margherita Ligure-Portofino | 3h05 | 7:00 PM Milan Centrale | 1 transfer | |
Regionale 12416 · Regionale Veloce 3079 | 4:17 PM Santa Margherita Ligure-Portofino | 3h18 | 7:35 PM Milan Centrale | 1 transfer | |
Regionale Veloce 3274 · Regionale 12076 · Regionale Veloce 3079 | 4:46 PM Santa Margherita Ligure-Portofino | 2h49 | 7:35 PM Milan Centrale | 2 transfers | |
Intercity 680 | 5:46 PM Santa Margherita Ligure-Portofino | 2h19 | 8:05 PM Milan Centrale | 0 transfersDirect | |
Regionale Veloce 3096+ FRECCIABIANCA 8620 | 6:03 PM Santa Margherita Ligure-Portofino | 2h37 | 8:40 PM Milan Centrale | 1 transfer | |
Regionale 12438+ Intercity 681 | 6:10 PM Santa Margherita Ligure-Portofino | 2h55 | 9:05 PM Milan Centrale | 1 transfer | |
Regionale Veloce 3278 · Regionale Veloce 3044 | 6:46 PM Santa Margherita Ligure-Portofino | 2h49 | 9:35 PM Milan Centrale | 1 transfer | |
Intercity 684 | 7:46 PM Santa Margherita Ligure-Portofino | 2h14 | 10:00 PM Milan Centrale | 0 transfersDirect | |
Regionale 12452 · Regionale Veloce 3047 | 7:55 PM Santa Margherita Ligure-Portofino | 3h40 | 11:35 PM Milan Centrale | 1 transfer | |
Regionale 12452+ Intercity 639 | 7:55 PM Santa Margherita Ligure-Portofino | 3h00 | 10:55 PM Milan Centrale | 1 transfer | |
Regionale 12458 · Regionale Veloce 2146 · Regionale Veloce 3047 | 8:14 PM Santa Margherita Ligure-Portofino | 3h21 | 11:35 PM Milan Centrale | 2 transfers | |
Intercity 679 · Intercity 514+ Regionale Veloce 3047 | 8:16 PM Santa Margherita Ligure-Portofino | 3h19 | 11:35 PM Milan Centrale | 2 transfers | |
| Sunday, June 21 | |||||
Regionale Veloce 3016 | 4:55 AM Santa Margherita Ligure-Portofino | 2h40 | 7:35 AM Milan Centrale | 0 transfersDirect | |
Intercity 652 | 6:07 AM Santa Margherita Ligure-Portofino | 2h18 | 8:25 AM Milan Centrale | 0 transfersDirect | |
Regionale 12316 · Regionale Veloce 3019 | 6:32 AM Santa Margherita Ligure-Portofino | 3h03 | 9:35 AM Milan Centrale | 1 transfer | |
Regionale 3257 · Regionale TTPER 19238 · Regionale Veloce TTPER 2466 | 6:37 AM Santa Margherita Ligure-Portofino | 6h08 | 12:45 PM Milan Centrale | 2 transfers | |
Regionale 12324 · Regionale Veloce 2120 · Regionale Veloce 2023 | 7:20 AM Santa Margherita Ligure-Portofino | 5h25 | 12:45 PM Milan Centrale | 2 transfers | |
Intercity 658 | 7:39 AM Santa Margherita Ligure-Portofino | 2h21 | 10:00 AM Milan Centrale | 0 transfersDirect | |
Regionale 12216+ Intercity 662 | 8:20 AM Santa Margherita Ligure-Portofino | 2h35 | 10:55 AM Milan Centrale | 1 transfer | |
Regionale Veloce 3261 · Regionale Veloce 3028 | 10:58 AM Santa Margherita Ligure-Portofino | 2h37 | 1:35 PM Milan Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Santa Margherita Ligure-Portofino to Milan Centrale run on average 23 times per day, taking around 2h 31m. Cheap train tickets for this journey start at $19 (€16) but you can travel from only $6 (€5) by bus.
There are 5 trains per day. The earliest train runs at 02:55, the last at 19:14. The fastest train covers the 79 miles (128 km) distance in 2h 18m.
Distance 79 miles (128 km) |
Average train duration 2h 31m |
Cheapest ticket price $19 (€16) |
Trains per day 23 |
Direct trains 5 |
Fastest train 2h 18m |
First train 2:55 AM |
Last train 7:14 PM |
Cheapest Month Jun |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Mon |
Least Busy Day Wed |
Discover the best of Milano Centrale — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milano Centrale trip today.
One of Milan’s premier art museums, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Italy’s largest science museum, featuring Leonardo-inspired displays, transport collections, and interactive exhibits in a former monastery.
A major museum of 20th-century Italian art facing Piazza del Duomo, especially noted for Futurist works and its central location.
Milan’s central square and the city’s main gathering point, ideal for first-time visitors and iconic city views.
A charming historic district known for elegant streets, art atmosphere, boutiques, and a classic Milanese walking experience.
Milan’s canal district, very popular for waterside walks, photos, and lively urban atmosphere, especially in the evening.
Milan’s signature saffron risotto, rich with butter and cheese, celebrated for its golden color and elegant, comforting flavor.
A classic Milanese breaded veal cutlet, traditionally cooked in butter and prized as one of the city’s most iconic dishes.
Braised veal shank, often served with risotto alla Milanese, valued for its tender meat and rich marrow-filled sauce.
Long-standing fine dining destination and one of Milan’s best-known vegetarian restaurants, refined and creative in style.
Well-known Milanese restaurant with a modern approach to Lombard classics such as risotto and mondeghili in a stylish setting.
Historic traditional trattoria known for classic Milanese dishes, old-world atmosphere, and a strong local reputation.
Prices are above the Italian average, especially near the station. Casual meals are manageable, but hotels and sit-down dining cost more.
Service is often included or covered by a coperto. Tipping is not mandatory; round up or leave EUR 1-5 for good service. Taxis can be rounded up.
Official public transport app
Milano Centrale, Milan -> Duomo di Milano, Milan
Find answers to the most common questions about traveling from Santa Margherita Ligure-Portofino to Milan Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

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