- Must visit
Centro Botín
Major contemporary art center on Santander’s waterfront, known for international exhibitions, cultural programming, and its striking Renzo Piano design.
Omio recommends booking the flight as it is the most popular option from Milan to Santander among Omio's users. If you are prioritising price take the bus with prices starting from $60. For those with little time consider booking a flight which can get you there in 2h 43m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.1 - 2.6kg. The ticket price range depends on the travel mode: a bus costs an average of $60, and a flight costs an average of $53.
Distance: 654 miles (1054 km)
Most popular Flight | Bus | Driving |
|---|---|---|
$251 Average price | $151 Average price Cheapest | $453 Average price (fuel + tolls) |
5h 43m Average total duration Fastest 2h 43m Onboard + 3h 0m Additional time* | 26h 10m Average total duration 25h 40m Onboard + 30m Additional time* | 14h 17m Average total duration (door-to-door) |
3.2 - 6.3kg CO2 emissions | 1.1 - 2.6kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Milan to Santander:
A bus is $100 (€82) less than a flight for this route with tickets for a flight from Milan to Santander costing on average $251 (€206).
Other travel options to Santander take longer:
Bus takes on average 25h 40m.
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a train from Milan to Santander and enjoy the approximately 654 miles (1054 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 05:00, the last at 13:58.
Distance 654 miles (1054 km) |
First train 5:00 AM |
Last train 1:58 PM |
High Season Oct - Dec |
Low Season Apr - Jun |
Busiest Day Wed |
Least Busy Day Wed |
Discover the best of Santander — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Santander trip today.
Major contemporary art center on Santander’s waterfront, known for international exhibitions, cultural programming, and its striking Renzo Piano design.
Important archaeological museum presenting prehistoric cave culture, Roman material, and key finds from across Cantabria.
Leading maritime museum covering Cantabrian Sea ecology, fishing, naval history, and aquariums; a strong family-friendly cultural stop.
Scenic headland combining gardens, sea views, beaches, and the palace grounds; ideal for walking and one of the city’s top experiences.
Santander’s best-known beach area, famous for its elegant promenade, broad sands, and lively atmosphere in good weather.
Grand waterfront promenade lined with historic buildings, sculptures, and access to the bay; essential for a first walk through Santander.
Lightly battered and fried squid rings, one of Santander’s most iconic tapas, especially popular for aperitif time by the bay.
High-quality Cantabrian anchovies, usually served in olive oil on bread or as a tapa; a flagship product of the region.
White tuna from the Cantabrian Sea, prized for its delicate texture and often served grilled, stewed, or preserved in olive oil.
Michelin-starred restaurant known for contemporary tasting menus rooted in Cantabrian products, with polished service and elegant ambiance.
Well-known Santander restaurant and tapas bar, famous for refined Cantabrian cuisine, seafood, and a lively central atmosphere.
Historic and established dining room serving classic Cantabrian dishes in a traditional setting with strong local character.
Moderate by Spanish standards: tapas and set lunches are affordable, while waterfront dining and summer stays cost more.
Tipping is modest. Round up or leave 5-10% in restaurants for good service. Small change in cafes is enough. Taxis are usually rounded up, and hotel tips are appreciated but not expected.
Official public transport app
Santander Airport, Santander -> Santander Railway Station, Santander
Find answers to the most common questions about traveling from Milan to Santander by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Santander, this guide helps you travel smarter and with confidence.

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