- Must visit
Museo del Territorio Ugo Granafei
Archaeological museum inside the castle with finds from the Messapian and Roman periods; essential for understanding the area's deep history.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest trains from Milan to Mesagne
Showing times and prices for Aug 22
Cheapest price
$109
Average price
$148
Fastest journey
9 h 16 m
Average duration
9 h 46 m
Trains per day
12
Distance
887 km
Cheap tickets
The best way to find a cheap train ticket from Milan to Mesagne is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Mesagne will cost around $148 if you buy it on the day, but the cheapest tickets can be found for only $109.
Fast trains
It's difficult to get from Milan to Mesagne without transferring at least once.
Intercity 603+
Regionale 343105:25 AM11h29Milan Centrale4:54 PMBrindisi Cittadella Della Ricerca$1091One-way1 transfer- Intercity 603+Regionale 343105:25 AM11h33Milan Centrale4:58 PMMesagne$1091One-way1 transfer
- Intercity 607+Regionale 343149:10 AM11h21Milan Porta Garibaldi8:31 PMMesagne$1091One-way1 transfer
- Intercity 607+Regionale 343149:10 AM11h17Milan Porta Garibaldi8:27 PMBrindisi Cittadella Della Ricerca$1091One-way1 transfer
FRECCIAROSSA 9805+Regionale 3431410:13 AM10h14Milan Porta Garibaldi8:27 PMBrindisi Cittadella Della Ricerca$1621One-way1 transfer
- FRECCIAROSSA 8807+Intercity 607+Regionale 3431411:15 AM9h16Milan Centrale8:31 PMMesagne$1681One-way2 transfers
- FRECCIAROSSA 9805+
Autobus FS Sud Est 5011310:13 AM9h22Milan Porta Garibaldi7:35 PMMesagne$1621One-way1 transfer - FRECCIAROSSA 9515 · FRECCIAROSSA 8801+Regionale 343107:00 AM9h58Milan Centrale4:58 PMMesagne$1971One-way2 transfers
- FRECCIAROSSA 9805+Regionale 3431410:30 AM10h01Milan Rogoredo8:31 PMMesagne$1621One-way1 transfer
- FRECCIAROSSA 9805+Regionale 3431410:13 AM10h14Milan Porta Garibaldi8:27 PMBrindisi Cittadella Della Ricerca$1621One-way1 transfer
Travel Information
Compare bus, flight, and train for Milan to Mesagne
Omio recommends booking the bus as it is the most popular option from Milan to Mesagne among Omio's users. If you are prioritising price take the train with prices starting from $93. For those with little time consider booking a flight which can get you there in 2h 28m. The ticket price range depends on the travel mode: a train costs an average of $93, and a flight costs an average of $30.
Distance: 551 miles (887 km)
Compare train with
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$93 Average price Cheapest | $107 Average price | $113 Average price | $206 Average price (fuel + tolls) |
13h 55m Average total duration 13h 25m Onboard + 30m Additional time* | 14h 20m Average total duration 13h 50m Onboard + 30m Additional time* | 5h 28m Average total duration Fastest 2h 28m Onboard + 3h 0m Additional time* | 10h 17m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Milan to Mesagne is a train with an average price of $93 (€75).
This is compared to other travel options from Milan to Mesagne:
A train is $14 (€11) less than a bus for this route with tickets for a bus from Milan to Mesagne costing on average $107 (€86).
A train is $19 (€16) less than a flight for this route with tickets for a flight from Milan to Mesagne costing on average $113 (€91).
The fastest way to travel from Milan to Mesagne is by flight with an average journey time of 2h 28m.
Other travel options to Mesagne take longer:
Train takes on average 13h 25m.
Bus takes on average 13h 50m.
It's helpful to compare your options as there are 3 ways to travel between Milan and Mesagne including taking a bus, flight, and train.
We recommend using the bus as it is the most popular way to get from Milan to Mesagne among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around $93 (€75) compared to roughly $206 (€165) in fuel and tolls — a saving of about $112 (€90). The journey takes 13h 25m versus 10h 17m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Milan to Mesagne train times
The table below shows live departures for Milan to Mesagne trains for tomorrow, Saturday, August 22. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| Intercity 603+Regionale 34310 | 5:25 AM Milan Centrale | 11h29 | 4:54 PM Brindisi Cittadella Della Ricerca | 1 transfer | |
| Intercity 603+Regionale 34310 | 5:25 AM Milan Centrale | 11h33 | 4:58 PM Mesagne | 1 transfer | |
| FRECCIAROSSA 9511+Regionale 34310 | 5:55 AM Milan Centrale | 11h03 | 4:58 PM Mesagne | 1 transfer | |
| FRECCIAROSSA 9515 · FRECCIAROSSA 8801+Regionale 34310 | 7:00 AM Milan Centrale | 9h58 | 4:58 PM Mesagne | 2 transfers | |
| FRECCIAROSSA 8803+Regionale 4417 · Regionale 34312 | 7:15 AM Milan Centrale | 11h21 | 6:36 PM Mesagne | 2 transfers | |
| Intercity 607+Regionale 34314 | 9:10 AM Milan Porta Garibaldi | 11h21 | 8:31 PM Mesagne | 1 transfer | |
| Intercity 607+Regionale 34314 | 9:10 AM Milan Porta Garibaldi | 11h17 | 8:27 PM Brindisi Cittadella Della Ricerca | 1 transfer | |
| FRECCIAROSSA 9805+Regionale 34314 | 10:13 AM Milan Porta Garibaldi | 10h14 | 8:27 PM Brindisi Cittadella Della Ricerca | 1 transfer | |
| FRECCIAROSSA 9805+Regionale 34314 | 10:13 AM Milan Porta Garibaldi | 10h18 | 8:31 PM Mesagne | 1 transfer | |
| FRECCIAROSSA 9805+Autobus FS Sud Est 50113 | 10:13 AM Milan Porta Garibaldi | 9h22 | 7:35 PM Mesagne | 1 transfer | |
| FRECCIAROSSA 9805+Regionale 34314 | 10:30 AM Milan Rogoredo | 10h01 | 8:31 PM Mesagne | 1 transfer | |
| FRECCIAROSSA 8807+Intercity 607+Regionale 34314 | 11:15 AM Milan Centrale | 9h16 | 8:31 PM Mesagne | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan to Mesagne by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sat
Aug 22
Aug 22
Sun
Aug 23
Aug 23
Mon
Aug 24
Aug 24
Tue
Aug 25
Aug 25
Wed
Aug 26
Aug 26
Thu
Aug 27
Aug 27
Fri
Aug 28
Aug 28
Journey information
Overview: Train from Milan to Mesagne
ItalyItaly
Trains from Milan to Mesagne run on average 7 times per day, taking around 13h 25m. Cheap train tickets for this journey start at $93 (€75) but you can travel from only $30 (€24) by flight.
The earliest train runs at 05:00, the last at 23:25. The fastest train covers the 551 miles (887 km) distance in 13h 25m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $30 (€24)
Distance 551 miles (887 km) |
Average train duration 13h 25m |
Cheapest ticket price $93 (€75) |
Trains per day 7 |
Fastest train 13h 25m |
First train 5:00 AM |
Last train 11:25 PM |
Cheapest Month Apr |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Sat |
Least Busy Day Sat |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $30 (€24)
Complete guide to Mesagne
Things to do in Mesagne
Discover the best of Mesagne — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Mesagne trip today.
- Recommended
Sale Espositive del Castello
Contemporary exhibition venue in the castle complex that hosts major temporary art shows, making Mesagne unexpectedly strong for culture.
- Recommended
Pinacoteca Civica
Civic exhibition rooms within a historic setting, often used for cultural programming that complements the castle museum visit.
- Must visit
Piazza Orsini del Balzo
Main square by the castle, ideal for orienting yourself and admiring the historic center's architecture and lively civic atmosphere.
- Must visit
Centro Storico di Mesagne
Mesagne's old town is a maze of whitewashed lanes, courtyards, and churches; the best area for walking and soaking up local character.
- Recommended
Piazza IV Novembre
Elegant central square framed by historic buildings and everyday local life; a pleasant stop between monuments and evening walks.
- Vegetarian
Orecchiette
Hand-rolled orecchiette pasta, often served with tomato sauce or greens. It is a hallmark of Puglian home cooking and widely eaten in Mesagne.
- Vegetarian
- Vegan
- Gluten-free
Fave E Cicorie
Broad bean purée with wild chicory. This rustic Puglian classic is traditional in the Brindisi area for its simple farm ingredients and bittersweet flavor.
- Vegetarian
Pittule
Small fried dough balls, plain or filled with tomato, olives, or capers. A beloved Salento street food and bakery snack eaten throughout Mesagne.
Ristorante Lily
Refined restaurant in a historic setting, known for creative Apulian cuisine and polished service. Suitable for a special dinner in Mesagne.
Osteria Del Vicoletto
Traditional local restaurant serving Puglian dishes, pasta, and grilled specialties in a warm, established atmosphere popular with residents.
Pizzeria Core Verde
Casual pizzeria and restaurant appreciated for wood-fired pizza and straightforward regional cooking. Good for an easy family meal.
Euro (€)
Mesagne is cheaper than major Italian tourist cities. Hotels, dining, and local transport are usually reasonably priced, with good value outside peak summer.
Average meal costs
- Budget
- €8-12 for a simple meal or takeaway.
- Mid-range
- €18-30 per person for a restaurant meal.
- Fine dining
- €50+ per person for upscale dining.
- Coffee
- €1.20-2.50 for coffee or cappuccino.
Tipping culture
Service is often included or modest. Round up or leave 5-10% at restaurants for good service. Taxis are usually rounded up. Small change is fine at cafes.
Ferrovie del Sud Est
Get the appOfficial public transport app
Prices
- Single ticket
- €1.10
- Day pass
- None
To the city center
Mesagne railway station -> Piazza Vittorio Emanuele II, Mesagne
- Distance
- 1 km
- Travel time
- 15 min
- Buy local bus tickets before boarding; sales are commonly at tobacconists or authorized shops.
- Card or contactless payment on board is not reliably available; carry a validated paper ticket or cash for taxis.
FAQs: Trains from Milan to Mesagne
Find answers to the most common questions about traveling from Milan to Mesagne by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mesagne, this guide helps you travel smarter and with confidence.
Train ticket prices from Milan to Mesagne can vary. The cheapest ticket starts at $93 (€75), while the average price is around $93 (€75).
The train from Milan to Mesagne takes 13h 25m and runs 7 per day.
The first train from Milan to Mesagne leaves at 5:00 AM.
The distance by train from Milan to Mesagne is 551 miles (887 km).
The last train from Milan to Mesagne leaves at 11:25 PM.
Unfortunately, there is no night train available from Milan to Mesagne.
The train station in Milan that goes to Mesagne is Milan Centrale, which connects to Mesagne.
The cheapest way to get from Milan to Mesagne is by flight, with a cost of around $30 (€24).
The train journey from Milan to Mesagne offers varied scenery, including views of the Po Valley, the Apennine Mountains, and the picturesque countryside of southern Italy, making it a pleasant and scenic route.
A day trip from Milan to Mesagne is not feasible as the journey takes 13h 25m and covers 551 miles (887 km). However, trains operate 7 times per day.
For a relaxed visit, spending 2 to 3 days in Mesagne allows ample time to explore its charming old town, historic sites, and enjoy local cuisine.
No, you cannot take the train from Milan to Mesagne.
Since both Milan and Mesagne are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Mesagne include Brindisi, Lecce, Taranto, Francavilla Fontana, Bari.
We recommend using the bus as it is the most popular way to get from Milan to Mesagne among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Mesagne, travelers should be cautious of petty theft such as pickpocketing, especially in crowded areas and public transportation. It's advisable to avoid poorly lit or isolated streets at night. Common scams are minimal but remaining vigilant when using taxis or booking transportation is recommended to ensure fair pricing. Overall, standard safety precautions typical for small Italian towns apply.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Milan to Mesagne
Most Milan to Mesagne trains use the Milano Centrale to Mesagne station pair, with some services arriving at Brindisi Cittadella Della Ricerca. Use this guide to compare Milan and Mesagne train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in Milan
Arrival train stations in Mesagne
Which Milan station do trains to Mesagne leave from?
Trains from Milan to Mesagne leave from Milano Centrale. The station is 1 miles (3 km) from Milan city centre at Piazza Duca d'Aosta, 1, 20124 Milan, Italy.
Milano CentralePiazza Duca d'Aosta, 1, 20124 Milan, Italy+39 892021
City-centre transport
Getting to Milano Centrale from Milan city centre
Milano Centrale is 2 km from Milan city centre. Public transport options include:
TrainRe51 · 11m · $2 · every ~5 min
BusNm3 · 9m · $2 · every ~1 min
60 · 31m · $2 · every ~10 min
Tram9 · 27m · $2 · every ~16 min
Subway3 · 11m · $2 · every ~25 min
Milano Centrale train station facilities and services
Milano Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: Venchi, Panzera Coffee, Burger King, Bar Motta, Caffè Napoli, VyTA Boulangerie, Spontini, Starbucks, Dispensa Emilia, McDonald's, & many more
Wi-Fi and ATMs
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
Tickets and information
The ticket office is open Mon - Sun: 05:50 - 22:20. Information desks are located next to the ticket office on the ground floor in the shopping gallery.
Luggage and lost property
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
Parking, taxis and toilets
Available at Milano Centrale: Parking, Taxis, WC.
Bike and car services
Available at Milano Centrale: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Milano Centrale: Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
Shops, hotels and contact
Nearby hotels include Glam Hotel Milano, NYX MIlan, iQ Hotel Milano.
Milano Porta GaribaldiPiazza Sigmund Freud, 1, Milan, Italy+39 892021
City-centre transport
Getting to Milano Porta Garibaldi from Milan city centre
Milano Porta Garibaldi is 2 km from Milan city centre. Public transport options include:
BusNm2 · 10m · $2 · every ~1 min
Tram2, 4 · 20m · $2 · every ~20 min
Subway2 · 8m · $2 · every ~30 min
Milano Porta Garibaldi train station facilities and services
Milano Porta Garibaldi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Bike Parking, and Bike Rental.
Food and drink
Food options include: Caffeteria Panni Caldi, Princi, Burgez, Bricco Café, U! Come tu mi vuoi, Autogrill, Culto
Wi-Fi and ATMs
Free Wi-Fi in the station. ATMs are located in the main hall.
Parking, taxis and toilets
Available at Milano Porta Garibaldi: Parking, Taxis, WC.
Bike and car services
Available at Milano Porta Garibaldi: Bike Parking, Bike Rental.
Accessibility
Accessibility facilities are available at Milano Porta Garibaldi: Accessible facilities such as ticket machines, toilets, and ramps and additional assistance as needed from 07:45 to 22:30.
Shops, hotels and contact
Nearby hotels include Hotel NH Milano Palazzo Moscova, AC Hotel by Marriott Milano, Tocq Hotel.
Milano RogoredoVia G Battista Cassinis 76, Milan, 20139, Italy+39 02 7740 4318
City-centre transport
Getting to Milano Rogoredo from Milan city centre
Milano Rogoredo is 5 km from Milan city centre. Public transport options include:
TrainRe, 2363, 2375, 2391, 2399, 3013, 3017, 3025, 3029, 3033, 3037, 3041, 3045, 3057, 3067, 3069, 3073, 3077, 33375 · 8m · $1 · every ~1 min
S1, S2, S13, S12 · 13m · $2 · every ~13 min
BusNm3 · 15m · $2 · every ~1 min
Bus · 28m
Subway3 · 10m · $2 · every ~25 min
Milano Rogoredo train station facilities and services
Milano Rogoredo has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Ristorante Pizzeria Il Moro, Osteria La Piola
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Milano Rogoredo. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Milano Rogoredo. Lost and found is available at the station.
Parking, taxis and toilets
Available at Milano Rogoredo: Parking, Taxis, WC.
Bike and car services
Available at Milano Rogoredo: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Milano Rogoredo: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Starhotels Business Palace, Hotel Mistral, Hotel Brenta Milano.
Which Mesagne station do trains from Milan arrive at?
Trains from Milan to Mesagne most often arrive at Mesagne. Some services arrive at Brindisi Cittadella Della Ricerca, so check your ticket before travel to confirm your Mesagne arrival station.
Mesagne72023 Mesagne, BR, Italy
Mesagne train station facilities and services
Mesagne has practical services for this route, including Accessibility.
Accessibility
Accessibility facilities are available at Mesagne.
Brindisi Cittadella Della Ricerca72100 Brindisi, BR, Italy
City-centre transport
Getting to Brindisi Cittadella Della Ricerca from Mesagne city centre
Brindisi Cittadella Della Ricerca is 4 km from Mesagne city centre. Public transport options include:
TrainRe · 5m · $1
Brindisi Cittadella Della Ricerca train station facilities and services
Brindisi Cittadella Della Ricerca has practical services for this route, including Accessibility.
Accessibility
Accessibility facilities are available at Brindisi Cittadella Della Ricerca.
Mesagne, Via Brindisi (Piazza Vittorio Emanuele II)72023 Mesagne, BR, Italy
Mesagne, Via Brindisi (Piazza Vittorio Emanuele II) train station facilities and services
Mesagne, Via Brindisi (Piazza Vittorio Emanuele II) has practical services for this route, including Accessibility.
Accessibility
Accessibility facilities are available at Mesagne, Via Brindisi (Piazza Vittorio Emanuele II).
More options for your journey from Milan to Mesagne
Here are some other resources that might have the information you need
Most popular trains to and from Mesagne and Milan
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
