Travel Information
Compare bus, train, and flight for Milan to Mesagne
Omio recommends booking the bus as it is the most popular option from Milan to Mesagne among Omio's users. If you are prioritising price take the train with prices starting from $91. For those with little time consider booking a flight which can get you there in 2h 20m. The ticket price range depends on the travel mode: a train costs an average of $91, and a flight costs an average of $114.
Distance: 551 miles (887 km)
Compare train with
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$98 Average price Cheapest | $107 Average price | $131 Average price | $197 Average price (fuel + tolls) |
13h 53m Average total duration 13h 23m Onboard + 30m Additional time* | 14h 8m Average total duration 13h 38m Onboard + 30m Additional time* | 5h 20m Average total duration Fastest 2h 20m Onboard + 3h 0m Additional time* | 10h 17m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Milan to Mesagne:
A train is $9 (€7) less than a bus for this route with tickets for a bus from Milan to Mesagne costing on average $107 (€88).
A train is $33 (€27) less than a flight for this route with tickets for a flight from Milan to Mesagne costing on average $131 (€108).
Other travel options to Mesagne take longer:
Train takes on average 13h 23m.
Bus takes on average 13h 38m.
Tickets start at around $98 (€81) compared to roughly $197 (€163) in fuel and tolls — a saving of about $99 (€82). The journey takes 13h 23m versus 10h 17m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Milan to Mesagne train times
The table below shows live departures for Milan to Mesagne trains for today, Thursday, July 2. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 6:05 AM Milan | 12h53 | 6:58 PM Mesagne | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan to Mesagne by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jul 03
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Journey information
Overview: Train from Milan to Mesagne
Trains from Milan to Mesagne run on average 6 times per day, taking around 13h 23m. Cheap train tickets for this journey start at $91 (€75) if you book in advance.
The earliest train runs at 05:00, the last at 23:25. The fastest train covers the 551 miles (887 km) distance in 12h 53m.
Distance 551 miles (887 km) |
Average train duration 13h 23m |
Cheapest ticket price $91 (€75) |
Trains per day 6 |
Fastest train 12h 53m |
First train 5:00 AM |
Last train 11:25 PM |
Cheapest Month Apr |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
FAQs: Trains from Milan to Mesagne
Find answers to the most common questions about traveling from Milan to Mesagne by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mesagne, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan to Mesagne
Most Milan to Mesagne trains use the Milano Centrale to Mesagne station pair, with some services arriving at Brindisi Cittadella Della Ricerca. Use this guide to compare Milan and Mesagne train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Which Milan station do trains to Mesagne leave from?
Getting to Milano Centrale from Milan city centre
Milano Centrale is 2 km from Milan city centre. Public transport options include:
Milano Centrale train station facilities and services
Milano Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: Venchi, Panzera Coffee, Burger King, Bar Motta, Caffè Napoli, VyTA Boulangerie, Spontini, Starbucks, Dispensa Emilia, McDonald's, & many more
Wi-Fi and ATMs
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
Tickets and information
The ticket office is open Mon - Sun: 05:50 - 22:20. Information desks are located next to the ticket office on the ground floor in the shopping gallery.
Luggage and lost property
Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
Parking, taxis and toilets
Available at Milano Centrale: Parking, Taxis, WC.
Bike and car services
Available at Milano Centrale: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Milano Centrale: Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
Shops, hotels and contact
Nearby hotels include Glam Hotel Milano, NYX MIlan, iQ Hotel Milano.
Getting to Milano Porta Garibaldi from Milan city centre
Milano Porta Garibaldi is 2 km from Milan city centre. Public transport options include:
Milano Porta Garibaldi train station facilities and services
Milano Porta Garibaldi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Bike Parking, and Bike Rental.
Food and drink
Food options include: Caffeteria Panni Caldi, Princi, Burgez, Bricco Café, U! Come tu mi vuoi, Autogrill, Culto
Wi-Fi and ATMs
Free Wi-Fi in the station. ATMs are located in the main hall.
Parking, taxis and toilets
Available at Milano Porta Garibaldi: Parking, Taxis, WC.
Bike and car services
Available at Milano Porta Garibaldi: Bike Parking, Bike Rental.
Accessibility
Accessibility facilities are available at Milano Porta Garibaldi: Accessible facilities such as ticket machines, toilets, and ramps and additional assistance as needed from 07:45 to 22:30.
Shops, hotels and contact
Nearby hotels include Hotel NH Milano Palazzo Moscova, AC Hotel by Marriott Milano, Tocq Hotel.
Getting to Milano Rogoredo from Milan city centre
Milano Rogoredo is 5 km from Milan city centre. Public transport options include:
Milano Rogoredo train station facilities and services
Milano Rogoredo has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Ristorante Pizzeria Il Moro, Osteria La Piola
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Milano Rogoredo. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Milano Rogoredo. Lost and found is available at the station.
Parking, taxis and toilets
Available at Milano Rogoredo: Parking, Taxis, WC.
Bike and car services
Available at Milano Rogoredo: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Milano Rogoredo: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Starhotels Business Palace, Hotel Mistral, Hotel Brenta Milano.
Which Mesagne station do trains from Milan arrive at?
Mesagne train station facilities and services
Mesagne has practical services for this route, including Accessibility.
Accessibility
Accessibility facilities are available at Mesagne.
Getting to Brindisi Cittadella Della Ricerca from Mesagne city centre
Brindisi Cittadella Della Ricerca is 4 km from Mesagne city centre. Public transport options include:
Brindisi Cittadella Della Ricerca train station facilities and services
Brindisi Cittadella Della Ricerca has practical services for this route, including Accessibility.
Accessibility
Accessibility facilities are available at Brindisi Cittadella Della Ricerca.
Mesagne, Via Brindisi (Piazza Vittorio Emanuele II) train station facilities and services
Mesagne, Via Brindisi (Piazza Vittorio Emanuele II) has practical services for this route, including Accessibility.
Accessibility
Accessibility facilities are available at Mesagne, Via Brindisi (Piazza Vittorio Emanuele II).
More options for your journey from Milan to Mesagne
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