The cheapest and fastest trains from Milan to Mesagne
Cheapest price
$109
Average price
$109
Fastest journey
12 h 53 m
Average duration
12 h 53 m
Trains per day
1
Distance
887 km
The best way to find a cheap train ticket from Milan to Mesagne is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Mesagne will cost around $109 if you buy it on the day, but the cheapest tickets can be found for only $109.
Of the 1 trains that leave Milan for Mesagne on Thu, May 14, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 14 the direct trains cover the 887 km distance in an average of 12 h 53 m but if you time it right, some trains will get you there in just 12 h 53 m .
On Thu, May 14 the slowest trains will take 12 h 53 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
6:05 AM12h53Milan6:58 PMMesagne$1091One-way0 transfers
6:05 AM12h53Milan6:58 PMMesagne$1091One-way0 transfers
Travel Information
Compare bus, train, and flight for Milan to Mesagne
Omio recommends booking the bus as it is the most popular option from Milan to Mesagne among Omio's users. If you are prioritising price take the train with prices starting from $94. For those with little time consider booking a flight which can get you there in 2h 20m. The ticket price range depends on the travel mode: a train costs an average of $94, and a flight costs an average of $118.
Distance: 551 miles (887 km)
Compare train with
| Train | Most popular Bus | Flight | Driving |
|---|---|---|---|
$101 Average price Cheapest | $110 Average price | $135 Average price | $204 Average price (fuel + tolls) |
13h 53m Average total duration 13h 23m Onboard + 30m Additional time* | 14h 8m Average total duration 13h 38m Onboard + 30m Additional time* | 5h 20m Average total duration Fastest 2h 20m Onboard + 3h 0m Additional time* | 10h 17m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Milan to Mesagne:
A train is $9 (€7) less than a bus for this route with tickets for a bus from Milan to Mesagne costing on average $110 (€88).
A train is $34 (€27) less than a flight for this route with tickets for a flight from Milan to Mesagne costing on average $135 (€108).
Other travel options to Mesagne take longer:
Train takes on average 13h 23m.
Bus takes on average 13h 38m.
Tickets start at around $101 (€81) compared to roughly $204 (€163) in fuel and tolls — a saving of about $102 (€82). The journey takes 13h 23m versus 10h 17m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Milan to Mesagne train times
The table below shows live departures for Milan to Mesagne trains for today, Wednesday, May 13. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Intercity 607+ Autobus FS Sud Est 50115 | 9:10 AM Milan Porta Garibaldi | 11h45 | 8:55 PM Mesagne | 1 transfer | |
FRECCIAROSSA 9805+ Treno 19984 effettuato con Bus BA414 | 10:13 AM Milan Porta Garibaldi | 9h32 | 7:45 PM Brindisi Cittadella Della Ricerca | 1 transfer | |
FRECCIAROSSA 9805+ Treno 19984 effettuato con Bus BA414 | 10:13 AM Milan Porta Garibaldi | 9h45 | 7:58 PM Mesagne | 1 transfer | |
InterCityNotte 755+ Treno 19974 effettuato con Bus BA404 | 9:50 PM Milan Centrale | 13h53 | 11:43 AM Mesagne | 1 transfer | |
InterCityNotte 755+ Autobus FS Sud Est 50031 | 9:50 PM Milan Centrale | 12h45 | 10:35 AM Mesagne | 1 transfer | |
InterCityNotte 755+ Treno 19974 effettuato con Bus BA404 | 9:50 PM Milan Centrale | 13h40 | 11:30 AM Brindisi Cittadella Della Ricerca | 1 transfer | |
| Thursday, May 14 | |||||
![]() | 6:05 AM Milan | 12h53 | 6:58 PM Mesagne | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan to Mesagne by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 14
May 15
May 16
May 17
May 18
May 19
May 20
Journey information
Overview: Train from Milan to Mesagne
Trains from Milan to Mesagne run on average 6 times per day, taking around 13h 23m. Cheap train tickets for this journey start at $94 (€75) if you book in advance.
The earliest train runs at 05:00, the last at 23:25. The fastest train covers the 551 miles (887 km) distance in 12h 53m.
Distance 551 miles (887 km) |
Average train duration 13h 23m |
Cheapest ticket price $94 (€75) |
Trains per day 6 |
Fastest train 12h 53m |
First train 5:00 AM |
Last train 11:25 PM |
Cheapest Month Apr |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Sat |
Least Busy Day Sat |
FAQs: Trains from Milan to Mesagne
Find answers to the most common questions about traveling from Milan to Mesagne by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Mesagne, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan to Mesagne
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
- Free Wi-Fi in the station.
- Caffeteria Panni Caldi
- Princi
- Burgez
- Bricco Café
- U! Come tu mi vuoi
- Autogrill
- Culto
- Accessible facilities such as ticket machines, toilets, and ramps and additional assistance as needed from 07:45 to 22:30.
- Hotel NH Milano Palazzo Moscova
- AC Hotel by Marriott Milano
- Tocq Hotel
- Metro lines: M2, M5
- Bus lines: 43, 56, 70, 94
- Train lines: R21, R31, S1, S11, S2, S5, S7, S8
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access is available from Via G Battista Cassinis.
- Ristorante Pizzeria Il Moro
- Osteria La Piola
- Outside the main entrance.
- Elevators, ramps.
- €1
- Starhotels Business Palace
- Hotel Mistral
- Hotel Brenta Milano
- Located in the main hall
- Avis
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-8 for trains to various destinations
- Hall 2: metro connections
- Metro: Line M3
- Bus: Several lines available
- Train: Regional and high-speed services
More options for your journey from Milan to Mesagne
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