Travel Information
Compare bus, train, and flight for Maryland Heights, MO to Chicago, IL
Omio recommends booking the train as it is the most popular option from Maryland Heights, MO to Chicago, IL among Omio's users. If you are prioritising price take the train with prices starting from €33. For those with little time consider booking a flight which can get you there in 1h 25m. The ticket price range depends on the travel mode: a train costs an average of €33, and a flight costs an average of €288.
Distance: 261 miles (421 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
€40 Average price Cheapest | €302 Average price | €45 Average price |
5h 12m Average total duration 4h 42m Onboard + 30m Additional time* | 4h 25m Average total duration Fastest 1h 25m Onboard + 3h 0m Additional time* | 7h 23m Average total duration 6h 53m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Maryland Heights, MO to Chicago, IL train times
The table below shows live departures for Maryland Heights, MO to Chicago, IL trains for today, Saturday, December 20. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:24 PM Maryland Heights, MO | 4h19 | 3:43 AM Chicago, IL | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Maryland Heights, MO to Chicago, IL by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
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Dec 27
Why should you book Maryland Heights to Chicago trains with Omio?
Amtrak operates all train services from Maryland Heights to Chicago. Omio is the only official third party seller for Amtrak tickets.
Why book with Omio vs Amtrak?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Amtrak with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Maryland Heights to Chicago.
Why book with Omio over Trainline and Rail Europe?
- Official reseller: Amtrak tickets can only be bought on Omio or Amtrak's website as Omio is the only official third party seller for Amtrak tickets. Trainline, RailEurope, and Rail.Ninja do not sell Amtrak tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Maryland Heights to Chicago.
Journey information
Overview: Train from Maryland Heights, MO to Chicago, IL
Trains from Maryland Heights, MO to Chicago, IL run on average 12 times per day, taking around 4h 42m. Cheap train tickets for this journey start at $41 (€33) if you book in advance.
There are 9 trains per day. The earliest train runs at 07:15, the last at 20:05. The fastest train covers the 261 miles (421 km) distance in 4h 11m.
Distance 261 miles (421 km) |
Average train duration 4h 42m |
Cheapest ticket price $41 (€33) |
Trains per day 12 |
Direct trains 9 |
Fastest train 4h 11m |
First train 07:15 |
Last train 20:05 |
Train companies: Amtrak from Maryland Heights, MO to Chicago, IL trainsAmtrak trains will get you between Maryland Heights, MO and Chicago, IL from $41 (€33). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from Maryland Heights, MO to Chicago, IL
Find answers to the most common questions about traveling from Maryland Heights, MO to Chicago, IL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Maryland Heights, MO to Chicago, IL
- 5:00 AM - 12:00 AM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 12:00 a.m. Departures can be made outside of opening hours. Access via Canal Street.
- The Chicago Firehouse Restaurant
- Lou Mitchell's
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $1
- The Kimpton Gray Hotel
- JW Marriott Chicago
- W Chicago - City Center
- Located in the main hall
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, Amtrak services
- Hall 2: Metra services
- Hall 3: food court and retail shops
- Bus: Several lines available
- CTA: Blue Line, Pink Line
More options for your journey from Maryland Heights, MO to Chicago, IL
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