Travel Information
Compare bus and train for Mainz to Enschede
Omio recommends booking the train as it is the most popular option from Mainz to Enschede among Omio's users. If you are prioritising price take the bus with prices starting from €37. For those with little time consider booking a train which can get you there in 5h 2m. The ticket price range depends on the travel mode: a bus costs an average of €37, and a train costs an average of €33.
Distance: 165 miles (267 km)
Compare train with
Most popular Train | Bus |
|---|---|
€55 Average price | €44 Average price Cheapest |
5h 32m Average total duration Fastest 5h 2m Onboard + 30m Additional time* | 13h 40m Average total duration 13h 10m Onboard + 30m Additional time* |
Direct Options | Direct Options |
Compare prices and tickets Mainz to Enschede by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Mainz to Enschede trains with Omio?
Deutsche Bahn (ICE,RB) as well as vlexx offer trains services from Mainz to Enschede. Omio is an official ticket reseller for all your travel options from Mainz to Enschede.
Why book with Omio vs Deutsche Bahn (ICE,RB)?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn (ICE,RB), but also compare tickets for the likes of vlexx to find the best option for your trip from Mainz to Enschede.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn (ICE,RB) with all available travel options, which are bus and train to ensure you get the best deal for traveling from Mainz to Enschede.
Why book with Omio over Trainline and Rail Europe?
- Multiple travel company options: While Deutsche Bahn (ICE,RB) tickets can be bought on Deutsche Bahn (ICE,RB)'s website or third party sellers, Omio allows you to compare with the likes of vlexx to help you choose the right option for your journey from Mainz to Enschede.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Mainz to Enschede.
Journey information
Overview: Train from Mainz to Enschede
Trains from Mainz to Enschede run on average 12 times per day, taking around 5h 2m. Cheap train tickets for this journey start at $41 (€33) if you book in advance.
The earliest train runs at 00:33, the last at 22:33. The fastest train covers the 165 miles (267 km) distance in 5h 24m.
Distance 165 miles (267 km) |
Average train duration 5h 2m |
Cheapest ticket price $41 (€33) |
Trains per day 12 |
Fastest train 5h 24m |
First train 00:33 |
Last train 22:33 |
Train companies: Deutsche Bahn, vlexx from Mainz to Enschede trainsDeutsche Bahn, vlexx trains will get you between Mainz and Enschede from $41 (€33). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
vlexx
FAQs: Trains from Mainz to Enschede
Find answers to the most common questions about traveling from Mainz to Enschede by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Enschede, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Mainz to Enschede
- Monday: 06:00 - 21:15
- Tuesday: 06:00 - 21:15
- Wednesday: 06:00 - 21:15
- Thursday: 06:00 - 21:15
- Friday: 06:00 - 21:15
- Saturday: 07:00 - 19:00
- Sunday: 08:00 - 20:00
- Mangal
- Asia Wok
- Bistrorante Midi
- McDonald's
- Advena Europa Hotel
- GuestHouse Mainz
- Terminus
- Hotel Moguntia
- McDonald's
- Cafe Extrablatt
- Hans im Glück
- The Big Easy
- Hyatt Regency Mainz
- Favorite Parkhotel
- Ibis Hotel Mainz City
- Hof Ehrenfels
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 1:00 a.m. Departures can be made outside of opening hours. Access via Stationsplein.
- Restaurant Fellini Enschede
- De Kater
- Outside the main entrance.
- Ramps, restrooms.
- €0.50
- IntercityHotel Enschede
- Van der Valk Hotel Enschede
- U Parkhotel
- Located in the main hall
- 885 places, covered
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany and regional destinations
- Bus: Several lines available
- Train: Intercity and Sprinter services
Most popular train connections from Mainz
More options for your journey from Mainz to Enschede
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