Florence Santa Maria Novella to Rome Tiburtina train with Italo

Tue, Jul 28
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Italo
Frecciarossa
Regionale
Intercity
Frecciargento
2,000+ travel companies
Italo
Frecciarossa
Regionale
Intercity
Frecciargento
2,000+ travel companies
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The cheapest and fastest trains from Florence Santa Maria Novella to Rome Tiburtina

Showing times and prices for Jul 28

Cheapest price

$31

Average price

$51

Fastest journey

2 h 30 m

Average duration

2 h 30 m

Trains per day

21

Distance

232 km

Cheap tickets

The best way to find a cheap train ticket from Florence Santa Maria Novella to Rome Tiburtina is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence Santa Maria Novella to Rome Tiburtina will cost around $51 if you buy it on the day, but the cheapest tickets can be found for only $31.

Fast trains

It's difficult to get from Florence Santa Maria Novella to Rome Tiburtina without transferring at least once.

  • RegionaleTreno 18251 effettuato con bus FI653 · Regionale Veloce 4125 · Regionale 20607
    12:40 AM9h20
    Florence Santa Maria Novella
    10:00 AMRome Tiburtina
    $311One-way
    2 transfers
  • RegionaleRegionale 4043 · Regionale 4137 · Regionale 23273
    4:28 PM5h50
    Florence Santa Maria Novella
    10:18 PMRome Tiburtina
    $311One-way
    2 transfers
  • RegionaleRegionale 18355 · Regionale 4129 · Regionale 20639
    6:08 AM6h07
    Florence Santa Maria Novella
    12:15 PMRome Tiburtina
    $311One-way
    2 transfers
  • RegionaleRegionale 4021 · Regionale 4131 · Regionale 20677
    10:28 AM5h32
    Florence Santa Maria Novella
    4:00 PMRome Tiburtina
    $311One-way
    2 transfers
  • RegionaleRegionale 4033+IntercityIntercity 511+RegionaleRegionale 20703
    1:28 PM4h47
    Florence Santa Maria Novella
    6:15 PMRome Tiburtina
    $481One-way
    2 transfers

Travel Information

Compare train, bus, and flight for Florence Santa Maria Novella to Rome Tiburtina

Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Rome Tiburtina among Omio's users. If you are prioritising price take the bus with prices starting from $6. For those with little time consider booking a flight which can get you there in 53m. The ticket price range depends on the travel mode: a bus costs an average of $6, and a flight costs an average of $63.

Distance: 144 miles (232 km)

Compare train with

Most popular
Train
Bus
Flight
Driving

$27

Average price

$15

Average price

Cheapest

$141

Average price

$65

Average price

(fuel + tolls)

2h 54m

Average total duration

2h 24m

Onboard

+

30m

Additional time*

4h 8m

Average total duration

3h 38m

Onboard

+

30m

Additional time*

3h 53m

Average total duration

Fastest

53m

Onboard

+

3h 0m

Additional time*

2h 53m

Average total duration

(door-to-door)

Italo

Most popular train company

FlixBus

Most popular bus company

ITA

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Florence Santa Maria Novella to Rome Tiburtina is a bus with an average price of $15 (€15).

This is compared to other travel options from Florence Santa Maria Novella to Rome Tiburtina:

A bus is $12 (€12) less than a train for this route with tickets for a train from Florence Santa Maria Novella to Rome Tiburtina costing on average $27 (€27).

A bus is $125 (€125) less than a flight for this route with tickets for a flight from Florence Santa Maria Novella to Rome Tiburtina costing on average $141 (€141).

The fastest way to travel from Florence Santa Maria Novella to Rome Tiburtina is by flight with an average journey time of 53m.

Other travel options to Rome Tiburtina take longer:

Train takes on average 2h 24m.

Bus takes on average 3h 38m.

It's helpful to compare your options as there are 3 ways to travel between Florence Santa Maria Novella and Rome Tiburtina including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Florence Santa Maria Novella to Rome Tiburtina among Omio's users.
Take the train. On this route, it beats driving on both time and money.

The journey is about 29m faster (2h 24m by train vs 2h 53m by car) and roughly $38 (€38) cheaper once you factor in fuel and tolls ($27 (€27) vs $65 (€65)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.

Direct services run with Italo, Frecciarossa, Regionale.

Driving is still worth considering if you want to stop along the way or need a car once you arrive.

Live departures

Florence Santa Maria Novella to Rome Tiburtina train times

The table below shows live departures for Florence Santa Maria Novella to Rome Tiburtina trains for today, Monday, July 27. You can also manually refresh the results below to see updated train journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
RegionaleRegionale Veloce 4045+IntercityIntercity 597+RegionaleRegionale 207355:00 PM Florence Santa Maria Novella
4h30
9:30 PM Rome Tiburtina2 transfers
FrecciarossaFRECCIAROSSA 9551+RegionaleRegionale 4110+TrenitaliaBUS FR4255:10 PM Florence Santa Maria Novella
3h09
8:19 PM Rome Tiburtina2 transfers
FrecciarossaFRECCIAROSSA 9555+RegionaleRegionale Veloce 4160+TrenitaliaBUS FR4276:10 PM Florence Santa Maria Novella
3h13
9:23 PM Rome Tiburtina2 transfers
FrecciarossaFRECCIAROSSA 9559+TrenitaliaBUS FR4317:10 PM Florence Santa Maria Novella
2h30
9:40 PM Rome Tiburtina1 transfer
FrecciarossaFRECCIAROSSA 89179+TrenitaliaBUS FR4338:10 PM Florence Santa Maria Novella
2h44
10:54 PM Rome Tiburtina1 transfer
FrecciarossaFRECCIAROSSA 89183+TrenitaliaBUS FR4359:10 PM Florence Santa Maria Novella
2h30
11:40 PM Rome Tiburtina1 transfer
Tuesday, July 28
RegionaleTreno 18251 effettuato con bus FI653 · Regionale Veloce 4125 · Regionale 2060712:40 AM Florence Santa Maria Novella
9h20
10:00 AM Rome Tiburtina2 transfers
RegionaleRegionale 18255+IntercityIntercity 501+RegionaleRegionale 232535:35 AM Florence Santa Maria Novella
5h02
10:37 AM Rome Tiburtina2 transfers
RegionaleRegionale 18355 · Regionale 4129 · Regionale 206396:08 AM Florence Santa Maria Novella
6h07
12:15 PM Rome Tiburtina2 transfers
RegionaleRegionale 4019+IntercityIntercity 583+RegionaleRegionale 206599:28 AM Florence Santa Maria Novella
4h47
2:15 PM Rome Tiburtina2 transfers
FrecciarossaFRECCIAROSSA 9583+TrenitaliaBUS FR40510:10 AM Florence Santa Maria Novella
2h30
12:40 PM Rome Tiburtina1 transfer
RegionaleRegionale 4021 · Regionale 4131 · Regionale 2067710:28 AM Florence Santa Maria Novella
5h32
4:00 PM Rome Tiburtina2 transfers
FrecciarossaFRECCIAROSSA 9527+TrenitaliaBUS FR40911:10 AM Florence Santa Maria Novella
2h30
1:40 PM Rome Tiburtina1 transfer
FrecciarossaFRECCIAROSSA 9587+TrenitaliaBUS FR41112:10 PM Florence Santa Maria Novella
2h30
2:40 PM Rome Tiburtina1 transfer
FrecciarossaFRECCIAROSSA 9535+TrenitaliaBUS FR4131:10 PM Florence Santa Maria Novella
2h30
3:40 PM Rome Tiburtina1 transfer
RegionaleRegionale 4033+IntercityIntercity 511+RegionaleRegionale 207031:28 PM Florence Santa Maria Novella
4h47
6:15 PM Rome Tiburtina2 transfers
RegionaleRegionale 4033+IntercityIntercity 511+RegionaleRegionale 207031:28 PM Florence Santa Maria Novella
4h47
6:15 PM Rome Tiburtina2 transfers
FrecciarossaFRECCIAROSSA 9539+TrenitaliaBUS FR4152:10 PM Florence Santa Maria Novella
2h30
4:40 PM Rome Tiburtina1 transfer
FrecciarossaFRECCIAROSSA 9543+RegionaleRegionale Veloce 4732+TrenitaliaBUS FR4193:10 PM Florence Santa Maria Novella
3h00
6:10 PM Rome Tiburtina2 transfers
FrecciarossaFRECCIAROSSA 9547+TrenitaliaBUS FR4214:10 PM Florence Santa Maria Novella
2h30
6:40 PM Rome Tiburtina1 transfer
RegionaleRegionale 4043 · Regionale 4137 · Regionale 232734:28 PM Florence Santa Maria Novella
5h50
10:18 PM Rome Tiburtina2 transfers

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Florence Santa Maria Novella to Rome Tiburtina by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Florence Santa Maria Novella to Rome Tiburtina trains with Omio?

Italo as well as Frecciarossa, Regionale, Intercity, Frecciargento and more offer trains services from Florence Santa Maria Novella to Rome Tiburtina.
Omio is the only official third party seller for Italo tickets.

Why book with Omio vs Italo?

  • Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Regionale, Intercity or Frecciargento to find the best option for your trip from Florence Santa Maria Novella to Rome Tiburtina.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Italo with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Florence Santa Maria Novella to Rome Tiburtina.

Journey information

Overview: Train from Florence Santa Maria Novella to Rome Tiburtina

ItalyItaly
ItalyItaly
Icon of train

Trains from Florence Santa Maria Novella to Rome Tiburtina run on average 53 times per day, taking around 2h 24m. Cheap train tickets for this journey start at $20 (€20) but you can travel from only $6 (€6) by bus.

There are 43 trains per day. The earliest train runs at 03:45, the last at 21:43. The fastest train covers the 144 miles (232 km) distance in 1h 26m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $6 (€6)
Distance
144 miles (232 km)
Average train duration
2h 24m
Cheapest ticket price
$20 (€20)
Trains per day
53
Direct trains
43
Fastest train
1h 26m
First train
3:45 AM
Last train
9:43 PM
Cheapest Month
Jun
Cheapest Day
Sat
High Season
Apr - Jun
Low Season
Jan - Mar
Busiest Day
Thu
Least Busy Day
Mon
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $6 (€6)

Train companies: Italo, Frecciarossa, Regionale, Intercity, Frecciargento from Florence Santa Maria Novella to Rome Tiburtina trainsItalo, Frecciarossa, Regionale, Intercity, Frecciargento trains will get you between Florence Santa Maria Novella and Rome Tiburtina from $6 (€6). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Italo

About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Average Duration
1h 26m
Cheapest Price
$26 (€26)
Italo frequency
22 a day
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone

Frecciarossa

About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
1h 24m
Cheapest Price
$65 (€65)
Frecciarossa frequency
25 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone

Regionale

About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
3h 20m
Cheapest Price
$25 (€25)
Regionale frequency
8 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone

Intercity

About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Duration
3h 15m
Cheapest Price
$20 (€20)
Intercity frequency
4 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone

Frecciargento

About
Frecciargento is a high-speed train service operated by Trenitalia, the national railway company of Italy. It runs on the most popular routes throughout the country, connecting major cities such as Rome, Milan, Florence, and Venice. Frecciargento trains offer a comfortable and convenient way to travel, with a range of ticket types available, including Economy, Standard, and Business. Onboard facilities include air-conditioning, power sockets, and free Wi-Fi. Frecciargento trains are fast and reliable, with journey times of up to four hours between Rome and Milan. They are a great way to explore Italy in style and comfort.
Luggage & cancellation policy
Frecciargento frequency
2 a day
Luggage included
1 carry-on bag and 1 piece of luggage included
Luggage storage
Overhead racks, luggage areas at end of carriages, between seats
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Bar-bistro service with snacks, drinks, and light meals. At-seat service in First Class
Seat reservation
Seat reservation included in ticket price for all classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone

FAQs: Trains from Florence Santa Maria Novella to Rome Tiburtina

Find answers to the most common questions about traveling from Florence Santa Maria Novella to Rome Tiburtina by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome Tiburtina, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Florence Santa Maria Novella to Rome Tiburtina can vary. The cheapest ticket starts at $20 (€20), while the average price is around $27 (€27).
The train from Florence Santa Maria Novella to Rome Tiburtina takes 1h 26m and runs 53 per day.
The first train from Florence Santa Maria Novella to Rome Tiburtina leaves at 3:45 AM.
The distance by train from Florence Santa Maria Novella to Rome Tiburtina is 144 miles (232 km).
The last train from Florence Santa Maria Novella to Rome Tiburtina leaves at 9:43 PM.
Yes, there is a high-speed train from Florence Santa Maria Novella to Rome Tiburtina.
Yes, there is a direct train from Florence Santa Maria Novella to Rome Tiburtina. This service operates 43 times per day, provided by Italo, Frecciarossa, Regionale.
Unfortunately, there is no night train available from Florence Santa Maria Novella to Rome Tiburtina.
The cheapest way to get from Florence Santa Maria Novella to Rome Tiburtina is by bus, with a cost of around $6 (€6).
The train journey from Firenze Santa Maria Novella to Roma Tiburtina offers scenic views of the Tuscan countryside, rolling hills, and charming Italian villages, providing a picturesque experience for travelers.
Yes, a day trip from Firenze Santa Maria Novella to Roma Tiburtina is feasible with a journey time of 1h 26m and a distance of 144 miles (232 km). There are 49 trains per day.
Yes, you can take the train from Florence Santa Maria Novella to Rome Tiburtina.
Since both Florence Santa Maria Novella and Rome Tiburtina are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Rome Tiburtina include Fiumicino, Tivoli, Terni, Orte, Monterotondo.
We recommend using the train as it is the most popular way to get from Florence Santa Maria Novella to Rome Tiburtina among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular train stations

Popular train stations from Florence Santa Maria Novella to Rome Tiburtina

Most Florence Santa Maria Novella to Rome Tiburtina trains use the Firenze Santa Maria Novella to Roma Termini station pair. Use this guide to compare Florence Santa Maria Novella and Rome Tiburtina train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.

Departure train stations in Florence
Arrival train stations in Rome
Firenze Santa Maria NovellaPiazza della Stazione, 1, 50123 Florence, Italy+39 0552352595WifiLockersParkingDiningATMTaxisAccessibilityWCHotelTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
City-centre transport

Getting to Firenze Santa Maria Novella from Florence city centre

Firenze Santa Maria Novella is 1 km from Florence city centre. Public transport options include:

TramT2 · 4m · $2 · every ~21 min

Firenze Santa Maria Novella train station facilities and services

Firenze Santa Maria Novella has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.

Food and drink

Food options include: 12oz Coffee Joint, Casa Maioli, Don Nino, Fratelli Cuore, McDonald´s, Panella, Segafredo Zanetti, Spizzico, Venchi, & many more

Wi-Fi and ATMs

Free WiFi (30 minutes limit). ATMs are located in the basement in the shopping center next to the Feltrinelli bookshop and between Celio and Mango shops.

Tickets and information

The ticket office is open Mon - Sun: 06:00 - 21:00. Information desks are located inside and outside the station.

Luggage and lost property

Luggage storage is provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.

Parking, taxis and toilets

Available at Firenze Santa Maria Novella: Parking, Taxis, WC.

Bike and car services

Available at Firenze Santa Maria Novella: Bike Parking, Bike Rental, Car Rental.

Accessibility

Accessibility facilities are available at Firenze Santa Maria Novella: Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.

Shops, hotels and contact

Nearby hotels include Hotel Luxor Florence, Joy Hotel Florence, Diplomat Hotel Florence.

More options for your journey from Florence Santa Maria Novella to Rome Tiburtina

Here are some other resources that might have the information you need

Most popular trains to and from Rome Tiburtina and Florence Santa Maria Novella

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