- Must visit
USS Midway Museum
A large aircraft carrier museum on the waterfront with restored aircraft, flight deck exhibits, and naval history. One of the city's most visited cultural attractions.
Cheapest price
$975
Average price
$975
Fastest journey
2 d 9 h 20 m
Average duration
2 d 9 h 20 m
Trains per day
1
Distance
2499 km
The best way to find a cheap train ticket from Brentwood, MO to San Diego, CA is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brentwood, MO to San Diego, CA will cost around $975 if you buy it on the day, but the cheapest tickets can be found for only $975.
It's difficult to get from Brentwood, MO to San Diego, CA without transferring at least 3 times.


Omio recommends booking the flight as it is the most popular option from Brentwood, MO to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $227. For those with little time consider booking a flight which can get you there in 8h 18m. The ticket price range depends on the travel mode: a bus costs an average of $227, and a train costs an average of $347.
Distance: 1552 miles (2499 km)
| Train | Most popular Flight | Bus | Driving |
|---|---|---|---|
$416 Average price | $232 Average price | $228 Average price Cheapest | $361 Average price (fuel + tolls) |
64h 24m Average total duration 63h 54m Onboard + 30m Additional time* | 11h 18m Average total duration Fastest 8h 18m Onboard + 3h 0m Additional time* | 48h 40m Average total duration 48h 10m Onboard + 30m Additional time* | 26h 26m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Brentwood, MO to San Diego, CA:
A bus is $4 (€3) less than a flight for this route with tickets for a flight from Brentwood, MO to San Diego, CA costing on average $232 (€191).
A bus is $188 (€155) less than a train for this route with tickets for a train from Brentwood, MO to San Diego, CA costing on average $416 (€342).
Other travel options to San Diego, CA take longer:
Bus takes on average 48h 10m.
Train takes on average 63h 54m.
Tickets start at around $416 (€342) compared to roughly $361 (€297) in fuel and tolls — a saving of about $-55.12 (€-45.34). The journey takes 63h 54m versus 26h 26m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
The table below shows live departures for Brentwood, MO to San Diego, CA trains for tomorrow, Monday, July 13. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:44 AM Brentwood, MO | 57h20 | 10:04 AM San Diego, CA | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Brentwood, MO to San Diego, CA run on average 1 times per day, taking around 63h 54m. Cheap train tickets for this journey start at $347 (€285) but you can travel from only $227 (€187) by bus.
The earliest train runs at 02:10, the last at 02:10. The fastest train covers the 1552 miles (2499 km) distance in 63h 54m.
Distance 1552 miles (2499 km) |
Average train duration 63h 54m |
Cheapest ticket price $347 (€285) |
Trains per day 1 |
Fastest train 63h 54m |
First train 2:10 AM |
Last train 2:10 AM |
Cheapest Month Feb |
Cheapest Day Fri |
High Season Jan - Mar |
Low Season Jan - Mar |
Discover the best of San Diego — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect San Diego trip today.
A large aircraft carrier museum on the waterfront with restored aircraft, flight deck exhibits, and naval history. One of the city's most visited cultural attractions.
Balboa Park's flagship art museum, known for European old masters, South Asian art, and major rotating exhibitions in a landmark Spanish Colonial building.
Contemporary art museum with a major La Jolla campus and strong collection of postwar and current works, plus ocean-view architecture and installations.
San Diego's signature urban park, filled with gardens, plazas, museums, and Spanish Colonial architecture. It is one of the city's essential places to explore.
A scenic coastal area known for sea lions, turquoise water, dramatic cliffs, and some of the most photographed ocean views in San Diego.
A popular waterfront walking area with bay views, promenades, and public spaces near downtown, especially appealing at sunset and on casual strolls.
Baja-style fish tacos are a San Diego staple, usually made with battered or grilled local fish, cabbage, crema, and salsa in a corn tortilla.
A classic San Diego burrito filled with carne asada, fries, cheese, and salsa, reflecting the city’s Mexican borderland food culture.
A beloved local late-night dish of fries topped with carne asada, cheese, guacamole, sour cream, and salsa.
An iconic casual spot in Barrio Logan known for house-made tortillas, rice, beans, and traditional Mexican plates with a no-frills atmosphere.
A long-running waterfront seafood market and eatery loved for fresh fish sandwiches, chowder, and a classic San Diego harbor setting.
A popular casual restaurant serving upscale fried chicken, sandwiches, and local beers in a lively indoor-outdoor setting.
San Diego is pricey by U.S. standards, especially for hotels and dining near beaches and downtown.
Tip 18-20% at restaurants; 20%+ for great service. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff USD 2-5.
Find answers to the most common questions about traveling from Brentwood, MO to San Diego, CA by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

Most Brentwood, MO to San Diego, CA trains use the St. Louis Station to Santa Fe Depot station pair. Use this guide to compare Brentwood, MO and San Diego, CA train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Santa Fe Depot is 1 km from San Diego city centre. Public transport options include:
Santa Fe Depot has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food options include: The Fish Market, Karl Strauss Brewing Company
Free. ATMs are available in the train station.
Ticket office support is available at Santa Fe Depot. Information desks are located in the main hall.
Luggage storage is available at Santa Fe Depot. Lost and found is available at the station.
Available at Santa Fe Depot: Parking, Taxis, WC.
Available at Santa Fe Depot: Bike Parking, Car Rental.
Accessibility facilities are available at Santa Fe Depot: Ramps.
Nearby hotels include The Westin San Diego, The Guild Hotel, San Diego, a Tribute Portfolio Hotel, Embassy Suites by Hilton San Diego Bay Downtown.
Here are some other resources that might have the information you need