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Journey information
Overview: St. Louis, MO to Columbia, SC flight
USAUSA
Take a flight from St. Louis, MO to Columbia, SC and enjoy the approximately 601 miles (968 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest flight runs at 05:00, the last at 20:15. June is the cheapest month to fly.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $537 (€433)
Distance 601 miles (968 km) |
Average flight duration 4h 57m |
Flights per day 35 |
First flight 5:00 AM |
Last flight 8:15 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Best time to book 28 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $537 (€433)
Travel Information
Compare train for St. Louis, MO to Columbia, SC
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Columbia, SC among Omio's users. If you are prioritising price take the train with prices starting from $537. For those with little time consider booking a train which can get you there in 40h 10m. The ticket price range depends on the travel mode: a train costs an average of $537, and a train costs an average of $537.
Distance: 601 miles (968 km)
Compare train with
Most popular Train | Driving |
|---|---|
$537 Average price Cheapest | $153 Average price (fuel + tolls) |
40h 40m Average total duration Fastest 40h 10m Onboard + 30m Additional time* | 11h 26m Average total duration (door-to-door) |
Direct Options | Direct Options |
The cheapest way to travel from St. Louis, MO to Columbia, SC is a train with an average price of $537 (€433).
The fastest way to travel from St. Louis, MO to Columbia, SC is by flight with an average journey time of 4h 57m.
Other travel options to Columbia, SC take longer:
Train takes on average 40h 10m.
Yes, you can take a train between St. Louis, MO and Columbia, SC.
We recommend using the flight as it is the most popular way to get from St. Louis, MO to Columbia, SC among Omio's users.
Compare prices and tickets St. Louis, MO to Columbia, SC by train
Compare train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Airlines: Republic Airlines from St. Louis, MO to Columbia, SCFind the best flights between St. Louis, MO to Columbia, SC with Omio's travel partners Republic Airlines from $537 (€433). We can find you the best deals, schedules and tickets when comparing and booking the best trip.
Republic Airlines
About
Republic Airways is a major regional airline in the United States, operating as a subsidiary of Republic Airways Holdings. It provides scheduled passenger service for American Airlines (as American Eagle), Delta Air Lines (as Delta Connection), and United Airlines (as United Express) using a fleet of Embraer 170 and 175 regional jets. Headquartered in Indianapolis, Indiana, Republic Airways operates over 900 daily flights to more than 80 cities across the U.S. and Canada. The company is known for its large fleet of Embraer E-Jets and its state-of-the-art training facilities. In April 2025, Republic Airways Holdings announced its acquisition of Mesa Air Group, which is expected to create the second-largest regional carrier in the U.S.
Luggage & cancellation policy
Republic Airlines frequency
3 a day
Luggage included
One carry-on bag (24 x 16 x 10) and one personal item
Additional luggage
Checked bags for a fee
Cancellation Policy
Tickets are non-refundable but may be cancelled for future flight credit minus applicable fees
Pregnant on board
Passengers can fly up to the end of their 36th week for single pregnancies and the end of their 32nd week for multiple pregnancies
Unaccompagned minor
Unaccompanied minor service is available for children ages 5-14. Must be booked directly with Republic Airlines
Amenities on board the airplane
USB plugs
Accessibility
Republic Airlines offers assistance for passengers with reduced mobility, including wheelchair services and priority boarding. Passengers are advised to request these services in advance to ensure availability and proper arrangements.
FAQs: St. Louis, MO to Columbia, SC Flight
Find answers to the most common questions about traveling from St. Louis, MO to Columbia, SC by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Columbia, SC, this guide helps you travel smarter and with confidence.
The earliest flight from St. Louis, MO to Columbia, SC leaves at 5:00 AM. Plan your trip with the Journey Planner from Omio.
The latest flight from St. Louis, MO to Columbia, SC leaves at 8:15 PM.
There are 35 flights a day from St. Louis, MO to Columbia, SC which require at least one change with Republic Airlines. Schedules can vary on holidays or weekends with fewer flights.
When taking a flight from St. Louis, MO to Columbia, SC, you can count on Republic Airlines for the best way to get you to Columbia, SC. You can also check all possible airlines who offer a service between St. Louis, MO and Columbia, SC and compare the amenities they offer before buying a plane ticket.
The cheapest month for a flight from St. Louis, MO to Columbia, SC is June.
Yes, you can take a train between St. Louis, MO and Columbia, SC.
Since neither St. Louis, MO nor Columbia, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
There is a time difference of 1 h between St. Louis, MO and Columbia, SC all year round.
The best events to attend in Columbia, SC include:
- Columbia Food and Wine Festival, a culinary celebration featuring local chefs, wine tastings, and gourmet experiences
- South Carolina State Fair, an annual fair with rides, games, and live entertainment celebrating the state's culture
- Columbia Artista Festival, a vibrant showcase of local artists, musicians, and performers in the heart of downtown.
The best holidays to experience in Columbia, SC include:
- Memorial Day, the unofficial start of summer with vibrant local events and outdoor activities
- Independence Day, spectacular fireworks and festive celebrations throughout the city
- Labor Day, a great time for enjoying warm weather and local festivals.
The best season to visit Columbia, SC is Spring or Fall. The best weather to explore Columbia, SC is during May-September.
We recommend using the flight as it is the most popular way to get from St. Louis, MO to Columbia, SC among Omio's users.
For domestic flights we recommend to arrive 1.5 to 2 hours before departure. Please check the website of your departure airport if in doubt. Some airports may offer booking time slots for security checks or offer additional information on when to get there based on time of day.
Most airlines permit carry-on bags that fit within specific dimensions (e.g., 22 x 14 x 9 inches or 56 x 36 x 23 cm), including handles and wheels. Bags must fit in the overhead bin or under the seat in front of you.
Many airlines impose weight limits, commonly ranging between 7 kg (15 lbs) and 12 kg (26 lbs). Typically, passengers are allowed one carry-on bag and one personal item (for example a purse, laptop bag, or backpack). Personal items must fit under the seat in front of you. Budget Airlines (like Ryanair or Wizz Air) have stricter size and weight limits, often requiring fees for larger carry-ons. Full-Service Airlines have more lenient policies, sometimes including more spacious dimensions or higher weight limits depending on your ticket class.
The list of items prohibited on an airplane varies by country and airline, but in general, the following items are not allowed in carry-on or checked baggage: Weapons and self-defence items, sharp objects, flammable materials, explosives, toxic substances, or liquids over 100ml (except for medications and baby essentials). In checked baggage, firearms (without authorization), explosives, large lithium batteries, and hazardous chemicals are prohibited. Electronic cigarettes must be in carry-on bags, while alcohol and dry ice have restrictions. Always check with your airline for specific regulations.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Columbia, SC, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded or tourist-heavy areas. Common scams include overcharging by unofficial taxi or rideshare drivers and fraudulent ticket sales for local events. It's advisable to use licensed transportation services and avoid displaying valuables openly to reduce risk.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular airports
Popular airports from St. Louis, MO to Columbia, SC
St. Louis
Columbia
The major airport for departures in St. Louis is St. Louis Lambert International Airport. Find all the information you need to know about services, amenities and connections at St. Louis Lambert International Airport for your trip from St. Louis to Columbia.
Amenities at airport
Wifi
Shopping
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Shower
Lounge
Lost and Found Office
Car Rentalinformation
Distance to city center
2 km
Car connection
I-70, Exit 236Wifi
- Free Wi-Fi available throughout the airport.
Shopping
- Shops in both terminals, including Hudson News and Tech on the Go.
Parking
- Parking available with short-term and long-term options, approximately 1.42€ ($1.50) per hour.
Dining
- Restaurants in both terminals, including fast food and sit-down options like Starbucks and Chili's
Taxis
- Available outside the terminal.
Accessibility
- Elevators, ramps
WC
- Available throughout both terminals.
Hotel
- Hotels nearby, such as Marriott St. Louis Airport within walking distance.
Shower
- Showers available in some lounges, access may require lounge fee.
Lounge
- Lounges available, including American Airlines Admirals Club.
Lost and Found Office
- Lost and Found located in terminal 1, contact airport for details.
Car Rental
- Car rental services available, including Hertz and Enterprise in terminal 1
Public transit options for St. Louis Lambert International Airport
- MetroLink Red Line, Lambert Airport terminal 1 & 2 stations, 35 minutes
The major airport for arrivals in Columbia is Columbia Metropolitan Airport. Find all the information you need to know about services, amenities and connections at Columbia Metropolitan Airport for your journey to Columbia from St. Louis.
Columbia Metropolitan Airport (CAE)
information
More options for your journey from St. Louis, MO to Columbia, SC
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Most popular flights to and from Columbia, SC and St. Louis, MO
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