- Must visit
National Museum
Prague’s flagship museum on Wenceslas Square, with major natural history, history, and cultural collections in a monumental Neo-Renaissance building.
Flights from Santorini (Island) to Prague depart on average 13 times per day, taking around 3h 11m. Cheap flight tickets for this journey start at $153 (€123) if you book in advance.
The earliest flight runs at 05:10, the last at 22:30. The fastest flight covers the 1094 miles (1761 km) distance in 5h 10m. February is the cheapest month to fly.
Distance 1094 miles (1761 km) |
Average flight duration 3h 11m |
Cheapest ticket price $153 (€123) |
Flights per day 13 |
Fastest flight 5h 10m |
First flight 5:10 AM |
Last flight 10:30 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 84 days |
Cheapest price
$317
Average price
$551
Fastest journey
6 h 40 m
Average duration
8 h 47 m
Flights per day
9
Distance
1761 km
The best way to find a cheap flight ticket from Santorini (Island) to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santorini (Island) to Prague will cost around $551 if you buy it on the day, but the cheapest tickets can be found for only $317.
It's difficult to get from Santorini (Island) to Prague without transferring at least once.
A3357 · A3866
A3349 · A3866
A3351 · A3866
A3353 · A3866
A3355 · A3866
A3357 · A3866
A3355 · A3866
BA689 · BA858
A3349 · A3866
A3353 · A3866Omio recommends booking the flight as it is the most popular option from Santorini (Island) to Prague among Omio's users. If you are prioritising price take the flight with prices starting from $153. For those with little time consider booking a flight which can get you there in 3h 11m. The ticket price range depends on the travel mode: a flight costs an average of $153, and a flight costs an average of $153.
Distance: 1094 miles (1761 km)
Most popular Flight | Driving |
|---|---|
$255 Average price Cheapest | $130 Average price (fuel + tolls) |
6h 11m Average total duration Fastest 3h 11m Onboard + 3h 0m Additional time* | 29h 30m Average total duration (door-to-door) |
![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options |
The table below shows live departures for Santorini (Island) to Prague flights for today, Sunday, May 31. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
A3355 · A3866 | 11:35 AM Santorini (Thira) National Airport | 7h30 | 6:05 PM Prague Vaclav Havel Airport | 1 transfer | |
EW9663 · EW9774 | 11:50 AM Santorini (Thira) National Airport | 9h05 | 7:55 PM Prague Vaclav Havel Airport | 1 transfer | |
A3357 · A3866 | 12:30 PM Santorini (Thira) National Airport | 6h35 | 6:05 PM Prague Vaclav Havel Airport | 1 transfer | |
BA689 · BA850 | 5:10 PM Santorini (Thira) National Airport | 17h20 | 9:30 AM Prague Vaclav Havel Airport | 1 transfer | |
BA689 · BA852 | 5:10 PM Santorini (Thira) National Airport | 21h25 | 1:35 PM Prague Vaclav Havel Airport | 1 transfer | |
LH123 · LH1392+ LH4339 | 5:45 PM Santorini (Thira) National Airport | 15h40 | 8:25 AM Prague Vaclav Havel Airport | 2 transfers | |
LH1688+ LH4339 | 5:45 PM Santorini (Thira) National Airport | 16h10 | 8:55 AM Prague Vaclav Havel Airport | 1 transfer | |
LH1402+ LH4363 | 6:10 PM Santorini (Thira) National Airport | 6h05 | 11:15 PM Prague Vaclav Havel Airport | 1 transfer | |
LH1392+ LH4363 | 6:10 PM Santorini (Thira) National Airport | 15h15 | 8:25 AM Prague Vaclav Havel Airport | 1 transfer | |
LH1394+ LH4363 | 6:10 PM Santorini (Thira) National Airport | 17h35 | 10:45 AM Prague Vaclav Havel Airport | 1 transfer | |
LH1402+ 4Y1221 | 6:10 PM Santorini (Thira) National Airport | 6h05 | 11:15 PM Prague Vaclav Havel Airport | 1 transfer | |
LH1392+ 4Y1221 | 6:10 PM Santorini (Thira) National Airport | 15h15 | 8:25 AM Prague Vaclav Havel Airport | 1 transfer | |
OS148 · OS643+ LX8337 | 8:55 PM Santorini (Thira) National Airport | 14h40 | 10:35 AM Prague Vaclav Havel Airport | 2 transfers | |
LH1394+ LX8337 · LX1068 | 8:55 PM Santorini (Thira) National Airport | 14h50 | 10:45 AM Prague Vaclav Havel Airport | 2 transfers | |
LX1484+ LX8337 | 8:55 PM Santorini (Thira) National Airport | 12h50 | 8:45 AM Prague Vaclav Havel Airport | 1 transfer | |
A3351 · A3866 | 6:00 AM Santorini (Thira) National Airport | 13h05 | 6:05 PM Prague Vaclav Havel Airport | 1 transfer | |
A3353 · A3866 | 8:25 AM Santorini (Thira) National Airport | 10h40 | 6:05 PM Prague Vaclav Havel Airport | 1 transfer | |
A3349 · A3866 | 9:20 AM Santorini (Thira) National Airport | 9h45 | 6:05 PM Prague Vaclav Havel Airport | 1 transfer | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Prague — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Prague trip today.
Prague’s flagship museum on Wenceslas Square, with major natural history, history, and cultural collections in a monumental Neo-Renaissance building.
A major museum complex preserving Prague’s Jewish heritage through synagogues, ceremonial objects, archives, and cemetery access.
A leading contemporary art venue in Holešovice known for ambitious exhibitions, design, and the striking Gulliver airship installation.
Prague’s historic central square, surrounded by major landmarks and lively at all hours, making it an essential first stop.
A picturesque district of Baroque streets, embassies, gardens, and hidden corners beneath Prague Castle, ideal for walking and photography.
A broad boulevard-like square central to modern Czech history, shopping, and city life, anchored by the National Museum.
Marinated beef sirloin with creamy root-vegetable sauce, bread dumplings, cranberry sauce, and whipped cream. One of the most classic Czech celebratory dishes.
Roast pork served with bread dumplings and braised cabbage. A cornerstone of traditional Czech home cooking and pub menus.
Czech-style goulash, usually beef, slower-cooked and less soupy than the Hungarian version, commonly served with dumplings. A staple in Prague pubs.
Michelin-starred restaurant offering contemporary Czech fine dining with seasonal ingredients and a sophisticated atmosphere.
Well-known restaurant near Old Town Square offering refined Czech classics in a polished but approachable setting.
Elegant grand cafe and restaurant known for excellent breakfasts, pastries, and upscale Czech and Central European dishes.
Moderate by European standards. Beer, transit, and casual meals are affordable; central hotels cost more.
Around 10% in restaurants for good service, often rounded up. Tip taxis modestly by rounding up. Not expected for counter service, but appreciated.
Official public transport app
Václav Havel Airport Prague, Prague -> Praha hlavní nádraží, Prague
Find answers to the most common questions about traveling from Santorini (Island) to Prague by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need