- Must visit
Royal Museums of Fine Arts of Belgium
Major museum complex with Old Masters, Magritte works, and Belgian art; one of the city’s essential cultural visits.
Flights from Santorini (Island) to Brussels depart on average 24 times per day, taking around 4h 9m. Cheap flight tickets for this journey start at $115 (€94) if you book in advance.
The earliest flight runs at 05:50, the last at 23:55. The fastest flight covers the 1443 miles (2323 km) distance in 5h 0m. June is the cheapest month to fly.
Distance 1443 miles (2323 km) |
Average flight duration 4h 9m |
Cheapest ticket price $115 (€94) |
Flights per day 24 |
Fastest flight 5h 0m |
First flight 5:50 AM |
Last flight 11:55 PM |
Cheapest Month Jun |
Cheapest Day Thu |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Tue |
Best time to book 3 days |
Cheapest price
$180
Average price
$398
Fastest journey
5 h 20 m
Average duration
6 h 35 m
Flights per day
23
Distance
2323 km
The best way to find a cheap flight ticket from Santorini (Island) to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santorini (Island) to Brussels will cost around $398 if you buy it on the day, but the cheapest tickets can be found for only $180.
It's difficult to get from Santorini (Island) to Brussels without transferring at least once.
A3361 · A3620
OS842 · OS331+
SN2094
OS842 · OS291
OS842+
OS8171
LH2625+
LH5628
A3351 · A3620
GQ341 · GQ800
A3353+
A33001
A3357 · A3622
A3351+
A33001Omio recommends booking the flight as it is the most popular option from Santorini (Island) to Brussels among Omio's users. If you are prioritising price take the flight with prices starting from $115. For those with little time consider booking a flight which can get you there in 4h 9m. The ticket price range depends on the travel mode: a flight costs an average of $115, and a flight costs an average of $115.
Distance: 1443 miles (2323 km)
Most popular Flight | Driving |
|---|---|
$259 Average price Cheapest | $175 Average price (fuel + tolls) |
7h 9m Average total duration Fastest 4h 9m Onboard + 3h 0m Additional time* | 37h 24m Average total duration (door-to-door) |
![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options |
The table below shows live departures for Santorini (Island) to Brussels flights for today, Friday, June 19. You can also manually refresh the results below to see updated flight journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
LH5632+ LH4339 | 7:25 PM Santorini (Thira) National Airport | 13h30 | 7:55 AM Brussels Airport | 1 transfer | |
LX786+ LX8337 | 8:00 PM Santorini (Thira) National Airport | 13h50 | 8:50 AM Brussels Airport | 1 transfer | |
VY2591 · VY8980 | 8:30 PM Santorini (Thira) National Airport | 14h15 | 9:45 AM Brussels Airport | 1 transfer | |
A3361 · A3620 | 10:00 PM Santorini (Thira) National Airport | 13h20 | 10:20 AM Brussels Airport | 1 transfer | |
| Saturday, June 20 | |||||
A3351+ A33001 | 6:00 AM Santorini (Thira) National Airport | 8h25 | 1:25 PM Brussels Airport | 1 transfer | |
A3351 · A3620 | 6:00 AM Santorini (Thira) National Airport | 5h20 | 10:20 AM Brussels Airport | 1 transfer | |
A3351 · A3622 | 6:00 AM Santorini (Thira) National Airport | 14h05 | 7:05 PM Brussels Airport | 1 transfer | |
A3353+ A33001 | 8:25 AM Santorini (Thira) National Airport | 6h00 | 1:25 PM Brussels Airport | 1 transfer | |
A3353 · A3622 | 8:25 AM Santorini (Thira) National Airport | 11h40 | 7:05 PM Brussels Airport | 1 transfer | |
GQ341 · GQ800 | 8:30 AM Santorini (Thira) National Airport | 5h35 | 1:05 PM Brussels Airport | 1 transfer | |
A3349 · A3622 | 9:20 AM Santorini (Thira) National Airport | 10h45 | 7:05 PM Brussels Airport | 1 transfer | |
A3355 · A3622 | 11:35 AM Santorini (Thira) National Airport | 8h30 | 7:05 PM Brussels Airport | 1 transfer | |
A3357 · A3622 | 12:30 PM Santorini (Thira) National Airport | 7h35 | 7:05 PM Brussels Airport | 1 transfer | |
LH206+ SN2592+ LH4363 | 5:35 PM Santorini (Thira) National Airport | 15h45 | 8:20 AM Brussels Airport | 2 transfers | |
LH832+ SN2268+ LH4363 | 5:35 PM Santorini (Thira) National Airport | 15h50 | 8:25 AM Brussels Airport | 2 transfers | |
GQ353 · GQ800 | 5:55 PM Santorini (Thira) National Airport | 26h00 | 6:55 PM Brussels Airport | 1 transfer | |
GQ800 · GQ355 | 6:15 PM Santorini (Thira) National Airport | 25h40 | 6:55 PM Brussels Airport | 1 transfer | |
This is the last flight of the day. | |||||
Find all the dates and times for this journey
Compare flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Discover the best of Brussels — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brussels trip today.
Major museum complex with Old Masters, Magritte works, and Belgian art; one of the city’s essential cultural visits.
Dedicated to René Magritte, with the world’s largest collection of his surrealist works in a central historic setting.
Celebrated museum in an Art Nouveau building, known for its global instrument collection and audio-guided displays.
Popular cultural hill and viewpoint linking the upper and lower city, especially photogenic at sunset.
Historic covered arcade of elegant passages, shops, and architecture, often highlighted in social media imagery.
Stylish square known for antiques, refined atmosphere, and easy access to nearby churches and museums.
Brussels classic of mussels steamed with white wine, celery, onions, or cream, served with crisp fries. It is one of the city’s most iconic comfort dishes.
Traditional Belgian beef and onion stew slowly cooked with dark beer, often slightly sweet-sour and served with fries or bread. A staple in Brussels brasseries.
Rustic mashed potatoes mixed with vegetables such as carrots, leeks, or spinach, often served with sausage or meat. The base preparation is a classic local side dish.
One of Brussels’ most famous fine-dining restaurants, celebrated for refined Belgian and French cuisine in an elegant Art Nouveau setting.
Respected restaurant specializing in carefully prepared Belgian cuisine and strong beer pairings, with a cozy, polished brasserie feel.
Well-known old-school restaurant serving generous Belgian specialties such as carbonnade, stoemp, and sausage in a rustic, bustling atmosphere.
Moderate by Western European standards. Food and transport are manageable, but central hotels cost more.
Service is usually included. Rounding up or leaving 5-10% for great restaurant service is appreciated, not required. Round up taxi fares; no tip is expected for bars or cafés.
Official public transport app
Brussels South Charleroi Airport, Brussels -> Bruxelles-Central, Brussels
Find answers to the most common questions about traveling from Santorini (Island) to Brussels by flight. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest flight, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

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